SrasV1, PascalFrancis, Corpus, bibRecord, 000009

Evaluating the virucidal efficacy of hydrogen peroxide vapour

Identifieur interne : 000009 ( PascalFrancis/Corpus ); précédent : 000008; suivant : 000010

Evaluating the virucidal efficacy of hydrogen peroxide vapour

Auteurs : S. M. Goyal ; Y. Chander ; S. Yezli ; J. A. Otter

Source :

The Journal of hospital infection [ 0195-6701 ] ; 2014.

RBID : Pascal:14-0118111

Descripteurs français

Pascal (Inist)
- Grippe, Gastroentérite, Syndrome respiratoire aigu sévère, Antiviral, Peroxyde Hydrogène, Désinfection, Décontamination, Papillomavirus humain, Calicivirus félin, Santé publique, Norovirus.

English descriptors

KwdEn :
- Antiviral, Decontamination, Disinfection, Feline calicivirus, Gastroenteritis, Human papillomavirus, Influenza, Norovirus, Peroxides Hydrogen, Public health, Severe acute respiratory syndrome.

Abstract

Background: Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents. Aim: To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV). Methods: The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m³ environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL. Findings: No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes. Conclusion: HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A11	`02`	`1`		`@1 CHANDER (Y.)`
A11	`03`	`1`		`@1 YEZLI (S.)`
A11	`04`	`1`		`@1 OTTER (J. A.)`
A14	`01`			`@1 Department of Veterinary Population Medicine, University of Minnesota @2 Saint Paul, MN @3 USA @Z 1 aut. @Z 2 aut.`
A14	`02`			`@1 Bioquell UK Ltd @2 Andover @3 GBR @Z 3 aut. @Z 4 aut.`
A14	`03`			`@1 Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy's and St Thomas' NHS Foundation Trust @3 GBR @Z 4 aut.`
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A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 18802 @5 354000500459300040`
A44				`@0 0000 @1 © 2014 INIST-CNRS. All rights reserved.`
A45				`@0 31 ref.`
A47	`01`	`1`		`@0 14-0118111`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 The Journal of hospital infection`
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C01	`01`		`ENG`	@0 Background: Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents. Aim: To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV). Methods: The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m³ environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL. Findings: No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes. Conclusion: HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.
C02	`01`	`X`		`@0 002B05C02C`
C02	`02`	`X`		`@0 002B02S05`
C02	`03`	`X`		`@0 002B05A02`
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C03	`01`	`X`	`ENG`	`@0 Influenza @5 01`
C03	`01`	`X`	`SPA`	`@0 Gripe @5 01`
C03	`02`	`X`	`FRE`	`@0 Gastroentérite @5 02`
C03	`02`	`X`	`ENG`	`@0 Gastroenteritis @5 02`
C03	`02`	`X`	`SPA`	`@0 Gastroenteritis @5 02`
C03	`03`	`X`	`FRE`	`@0 Syndrome respiratoire aigu sévère @2 NM @5 03`
C03	`03`	`X`	`ENG`	`@0 Severe acute respiratory syndrome @2 NM @5 03`
C03	`03`	`X`	`SPA`	`@0 Síndrome respiratorio agudo severo @2 NM @5 03`
C03	`04`	`X`	`FRE`	`@0 Antiviral @5 04`
C03	`04`	`X`	`ENG`	`@0 Antiviral @5 04`
C03	`04`	`X`	`SPA`	`@0 Antiviral @5 04`
C03	`05`	`X`	`FRE`	`@0 Peroxyde Hydrogène @2 NA @2 NC @5 07`
C03	`05`	`X`	`ENG`	`@0 Peroxides Hydrogen @2 NA @2 NC @5 07`
C03	`05`	`X`	`SPA`	`@0 Peróxido Hidrógeno @2 NA @2 NC @5 07`
C03	`06`	`X`	`FRE`	`@0 Désinfection @5 08`
C03	`06`	`X`	`ENG`	`@0 Disinfection @5 08`
C03	`06`	`X`	`SPA`	`@0 Desinfección @5 08`
C03	`07`	`X`	`FRE`	`@0 Décontamination @5 09`
C03	`07`	`X`	`ENG`	`@0 Decontamination @5 09`
C03	`07`	`X`	`SPA`	`@0 Descontaminación @5 09`
C03	`08`	`X`	`FRE`	`@0 Papillomavirus humain @2 NW @5 10`
C03	`08`	`X`	`ENG`	`@0 Human papillomavirus @2 NW @5 10`
C03	`08`	`X`	`SPA`	`@0 Human papillomavirus @2 NW @5 10`
C03	`09`	`X`	`FRE`	`@0 Calicivirus félin @2 NW @5 11`
C03	`09`	`X`	`ENG`	`@0 Feline calicivirus @2 NW @5 11`
C03	`09`	`X`	`SPA`	`@0 Feline calicivirus @2 NW @5 11`
C03	`10`	`X`	`FRE`	`@0 Santé publique @5 14`
C03	`10`	`X`	`ENG`	`@0 Public health @5 14`
C03	`10`	`X`	`SPA`	`@0 Salud pública @5 14`
C03	`11`	`X`	`FRE`	`@0 Norovirus @4 CD @5 96`
C03	`11`	`X`	`ENG`	`@0 Norovirus @4 CD @5 96`
C07	`01`	`X`	`FRE`	`@0 Virose`
C07	`01`	`X`	`ENG`	`@0 Viral disease`
C07	`01`	`X`	`SPA`	`@0 Virosis`
C07	`02`	`X`	`FRE`	`@0 Infection`
C07	`02`	`X`	`ENG`	`@0 Infection`
C07	`02`	`X`	`SPA`	`@0 Infección`
C07	`03`	`X`	`FRE`	`@0 Papillomavirus @2 NW`
C07	`03`	`X`	`ENG`	`@0 Papillomavirus @2 NW`
C07	`03`	`X`	`SPA`	`@0 Papillomavirus @2 NW`
C07	`04`	`X`	`FRE`	`@0 Papovaviridae @2 NW`
C07	`04`	`X`	`ENG`	`@0 Papovaviridae @2 NW`
C07	`04`	`X`	`SPA`	`@0 Papovaviridae @2 NW`
C07	`05`	`X`	`FRE`	`@0 Virus @2 NW`
C07	`05`	`X`	`ENG`	`@0 Virus @2 NW`
C07	`05`	`X`	`SPA`	`@0 Virus @2 NW`
C07	`06`	`X`	`FRE`	`@0 Calicivirus @2 NW`
C07	`06`	`X`	`ENG`	`@0 Calicivirus @2 NW`
C07	`06`	`X`	`SPA`	`@0 Calicivirus @2 NW`
C07	`07`	`X`	`FRE`	`@0 Caliciviridae @2 NW`
C07	`07`	`X`	`ENG`	`@0 Caliciviridae @2 NW`
C07	`07`	`X`	`SPA`	`@0 Caliciviridae @2 NW`
C07	`08`	`X`	`FRE`	`@0 Pathologie de l'appareil digestif @5 37`
C07	`08`	`X`	`ENG`	`@0 Digestive diseases @5 37`
C07	`08`	`X`	`SPA`	`@0 Aparato digestivo patología @5 37`
C07	`09`	`X`	`FRE`	`@0 Pathologie de l'estomac @5 38`
C07	`09`	`X`	`ENG`	`@0 Gastric disease @5 38`
C07	`09`	`X`	`SPA`	`@0 Estómago patología @5 38`
C07	`10`	`X`	`FRE`	`@0 Pathologie de l'intestin @5 39`
C07	`10`	`X`	`ENG`	`@0 Intestinal disease @5 39`
C07	`10`	`X`	`SPA`	`@0 Intestino patología @5 39`
C07	`11`	`X`	`FRE`	`@0 Pathologie de l'appareil respiratoire @5 40`
C07	`11`	`X`	`ENG`	`@0 Respiratory disease @5 40`
C07	`11`	`X`	`SPA`	`@0 Aparato respiratorio patología @5 40`
C07	`12`	`X`	`FRE`	`@0 Pathologie des poumons @5 41`
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C07	`12`	`X`	`SPA`	`@0 Pulmón patología @5 41`
N21				`@1 153`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Format Inist (serveur)

NO :	PASCAL 14-0118111 INIST
ET :	Evaluating the virucidal efficacy of hydrogen peroxide vapour
AU :	GOYAL (S. M.); CHANDER (Y.); YEZLI (S.); OTTER (J. A.)
AF :	Department of Veterinary Population Medicine, University of Minnesota/Saint Paul, MN/Etats-Unis (1 aut., 2 aut.); Bioquell UK Ltd/Andover/Royaume-Uni (3 aut., 4 aut.); Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy's and St Thomas' NHS Foundation Trust/Royaume-Uni (4 aut.)
DT :	Publication en série; Niveau analytique
SO :	The Journal of hospital infection; ISSN 0195-6701; Royaume-Uni; Da. 2014; Vol. 86; No. 4; Pp. 255-259; Bibl. 31 ref.
LA :	Anglais
EA :	Background: Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents. Aim: To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV). Methods: The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m³ environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL. Findings: No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes. Conclusion: HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.
CC :	002B05C02C; 002B02S05; 002B05A02
FD :	Grippe; Gastroentérite; Syndrome respiratoire aigu sévère; Antiviral; Peroxyde Hydrogène; Désinfection; Décontamination; Papillomavirus humain; Calicivirus félin; Santé publique; Norovirus
FG :	Virose; Infection; Papillomavirus; Papovaviridae; Virus; Calicivirus; Caliciviridae; Pathologie de l'appareil digestif; Pathologie de l'estomac; Pathologie de l'intestin; Pathologie de l'appareil respiratoire; Pathologie des poumons
ED :	Influenza; Gastroenteritis; Severe acute respiratory syndrome; Antiviral; Peroxides Hydrogen; Disinfection; Decontamination; Human papillomavirus; Feline calicivirus; Public health; Norovirus
EG :	Viral disease; Infection; Papillomavirus; Papovaviridae; Virus; Calicivirus; Caliciviridae; Digestive diseases; Gastric disease; Intestinal disease; Respiratory disease; Lung disease
SD :	Gripe; Gastroenteritis; Síndrome respiratorio agudo severo; Antiviral; Peróxido Hidrógeno; Desinfección; Descontaminación; Human papillomavirus; Feline calicivirus; Salud pública
LO :	INIST-18802.354000500459300040
ID :	14-0118111

Links to Exploration step

Pascal:14-0118111

Le document en format XML

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<front><div type="abstract" xml:lang="en">Background: Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents. Aim: To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV). Methods: The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m<sup>3</sup>
 environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL. Findings: No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes. Conclusion: HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.</div>
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<fA14 i1="03"><s1>Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy's and St Thomas' NHS Foundation Trust</s1>
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<fC01 i1="01" l="ENG"><s0>Background: Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents. Aim: To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV). Methods: The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m<sup>3</sup>
 environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL. Findings: No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes. Conclusion: HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B05C02C</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B02S05</s0>
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<s5>01</s5>
</fC03>
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<s5>01</s5>
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<s2>NM</s2>
<s5>03</s5>
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<s2>NM</s2>
<s5>03</s5>
</fC03>
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<s2>NM</s2>
<s5>03</s5>
</fC03>
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<s5>04</s5>
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<s5>04</s5>
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<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Peroxyde Hydrogène</s0>
<s2>NA</s2>
<s2>NC</s2>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Peroxides Hydrogen</s0>
<s2>NA</s2>
<s2>NC</s2>
<s5>07</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Peróxido Hidrógeno</s0>
<s2>NA</s2>
<s2>NC</s2>
<s5>07</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Désinfection</s0>
<s5>08</s5>
</fC03>
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<s5>08</s5>
</fC03>
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<s5>08</s5>
</fC03>
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<s5>09</s5>
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<s5>09</s5>
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<fC03 i1="07" i2="X" l="SPA"><s0>Descontaminación</s0>
<s5>09</s5>
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<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Human papillomavirus</s0>
<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Human papillomavirus</s0>
<s2>NW</s2>
<s5>10</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Calicivirus félin</s0>
<s2>NW</s2>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Feline calicivirus</s0>
<s2>NW</s2>
<s5>11</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Feline calicivirus</s0>
<s2>NW</s2>
<s5>11</s5>
</fC03>
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<s5>14</s5>
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<s5>14</s5>
</fC03>
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<s5>14</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Norovirus</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="11" i2="X" l="ENG"><s0>Norovirus</s0>
<s4>CD</s4>
<s5>96</s5>
</fC03>
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</fC07>
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</fC07>
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<fC07 i1="02" i2="X" l="SPA"><s0>Infección</s0>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Papillomavirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Papillomavirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Papillomavirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Papovaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Papovaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Papovaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Calicivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Calicivirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Calicivirus</s0>
<s2>NW</s2>
</fC07>
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<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Caliciviridae</s0>
<s2>NW</s2>
</fC07>
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<s2>NW</s2>
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<s5>37</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Digestive diseases</s0>
<s5>37</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Aparato digestivo patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Pathologie de l'estomac</s0>
<s5>38</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Gastric disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Estómago patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="10" i2="X" l="FRE"><s0>Pathologie de l'intestin</s0>
<s5>39</s5>
</fC07>
<fC07 i1="10" i2="X" l="ENG"><s0>Intestinal disease</s0>
<s5>39</s5>
</fC07>
<fC07 i1="10" i2="X" l="SPA"><s0>Intestino patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="11" i2="X" l="FRE"><s0>Pathologie de l'appareil respiratoire</s0>
<s5>40</s5>
</fC07>
<fC07 i1="11" i2="X" l="ENG"><s0>Respiratory disease</s0>
<s5>40</s5>
</fC07>
<fC07 i1="11" i2="X" l="SPA"><s0>Aparato respiratorio patología</s0>
<s5>40</s5>
</fC07>
<fC07 i1="12" i2="X" l="FRE"><s0>Pathologie des poumons</s0>
<s5>41</s5>
</fC07>
<fC07 i1="12" i2="X" l="ENG"><s0>Lung disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="12" i2="X" l="SPA"><s0>Pulmón patología</s0>
<s5>41</s5>
</fC07>
<fN21><s1>153</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
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<server><NO>PASCAL 14-0118111 INIST</NO>
<ET>Evaluating the virucidal efficacy of hydrogen peroxide vapour</ET>
<AU>GOYAL (S. M.); CHANDER (Y.); YEZLI (S.); OTTER (J. A.)</AU>
<AF>Department of Veterinary Population Medicine, University of Minnesota/Saint Paul, MN/Etats-Unis (1 aut., 2 aut.); Bioquell UK Ltd/Andover/Royaume-Uni (3 aut., 4 aut.); Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy's and St Thomas' NHS Foundation Trust/Royaume-Uni (4 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>The Journal of hospital infection; ISSN 0195-6701; Royaume-Uni; Da. 2014; Vol. 86; No. 4; Pp. 255-259; Bibl. 31 ref.</SO>
<LA>Anglais</LA>
<EA>Background: Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents. Aim: To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV). Methods: The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m<sup>3</sup>
 environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL. Findings: No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes. Conclusion: HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.</EA>
<CC>002B05C02C; 002B02S05; 002B05A02</CC>
<FD>Grippe; Gastroentérite; Syndrome respiratoire aigu sévère; Antiviral; Peroxyde Hydrogène; Désinfection; Décontamination; Papillomavirus humain; Calicivirus félin; Santé publique; Norovirus</FD>
<FG>Virose; Infection; Papillomavirus; Papovaviridae; Virus; Calicivirus; Caliciviridae; Pathologie de l'appareil digestif; Pathologie de l'estomac; Pathologie de l'intestin; Pathologie de l'appareil respiratoire; Pathologie des poumons</FG>
<ED>Influenza; Gastroenteritis; Severe acute respiratory syndrome; Antiviral; Peroxides Hydrogen; Disinfection; Decontamination; Human papillomavirus; Feline calicivirus; Public health; Norovirus</ED>
<EG>Viral disease; Infection; Papillomavirus; Papovaviridae; Virus; Calicivirus; Caliciviridae; Digestive diseases; Gastric disease; Intestinal disease; Respiratory disease; Lung disease</EG>
<SD>Gripe; Gastroenteritis; Síndrome respiratorio agudo severo; Antiviral; Peróxido Hidrógeno; Desinfección; Descontaminación; Human papillomavirus; Feline calicivirus; Salud pública</SD>
<LO>INIST-18802.354000500459300040</LO>
<ID>14-0118111</ID>
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Evaluating the virucidal efficacy of hydrogen peroxide vapour

Evaluating the virucidal efficacy of hydrogen peroxide vapour

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