SrasV1, PascalFrancis, Checkpoint, bibRecord, 000831

In vitro inhibition of SARS virus replication by human interferons

Identifieur interne : 000831 ( PascalFrancis/Checkpoint ); précédent : 000830; suivant : 000832

In vitro inhibition of SARS virus replication by human interferons

Auteurs : Helena Dahl [Suède] ; Annika Linde [Suède] ; Örjan Strannegard [Suède]

Source :

Scandinavian journal of infectious diseases [ 0036-5548 ] ; 2004.

RBID : Pascal:05-0060697

Descripteurs français

Pascal (Inist)
- Syndrome respiratoire aigu sévère, Interféron, In vitro, Réplication, Homme, Virus.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Human, In vitro, Interferon, Replication, Severe acute respiratory syndrome, Virus.

Abstract

Four different types of human interferon, interferon-β (IFN-β), recombinant IFN-α2a and IFN-a2b and natural IFN-α were tested for antiviral activity against SARS-coronavirus. The experiments were performed using in vitro cultivated monkey Vero E6 cells. IFN-β was found to be the most highly active antiviral agent, followed by natural IFN-a, whereas the 2 recombinant IFN-a2 species were poorly active in the system used. These results suggest that IFN-β as well as natural IFN-a may be used for the treatment of SARS.

Affiliations:

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Pascal:05-0060697

Le document en format XML

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In vitro inhibition of SARS virus replication by human interferons

In vitro inhibition of SARS virus replication by human interferons

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri