Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019.
Identifieur interne : 003890 ( Ncbi/Merge ); précédent : 003889; suivant : 003891Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019.
Auteurs : Yu-Han Xing [République populaire de Chine] ; Wei Ni [République populaire de Chine] ; Qin Wu [République populaire de Chine] ; Wen-Jie Li [République populaire de Chine] ; Guo-Ju Li [République populaire de Chine] ; Wen-Di Wang [République populaire de Chine] ; Jian-Ning Tong [République populaire de Chine] ; Xiu-Feng Song [République populaire de Chine] ; Gary Wing-Kin Wong [République populaire de Chine] ; Quan-Sheng Xing [République populaire de Chine]Source :
- Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi [ 1995-9133 ] ; 2020.
Abstract
To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19).
DOI: 10.1016/j.jmii.2020.03.021
PubMed: 32276848
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Electronic address: xingqs0532@163.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32276848</idno><idno type="pmid">32276848</idno><idno type="doi">10.1016/j.jmii.2020.03.021</idno><idno type="wicri:Area/PubMed/Corpus">000226</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000226</idno><idno type="wicri:Area/PubMed/Curation">000226</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000226</idno><idno type="wicri:Area/PubMed/Checkpoint">000293</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000293</idno><idno 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Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author><author><name sortKey="Wu, Qin" sort="Wu, Qin" uniqKey="Wu Q" first="Qin" last="Wu">Qin Wu</name><affiliation wicri:level="1"><nlm:affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author><author><name sortKey="Li, Wen Jie" sort="Li, Wen Jie" uniqKey="Li W" first="Wen-Jie" last="Li">Wen-Jie Li</name><affiliation wicri:level="1"><nlm:affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author><author><name sortKey="Li, Guo Ju" sort="Li, Guo Ju" uniqKey="Li G" first="Guo-Ju" last="Li">Guo-Ju Li</name><affiliation wicri:level="1"><nlm:affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Wen Di" sort="Wang, Wen Di" uniqKey="Wang W" first="Wen-Di" last="Wang">Wen-Di Wang</name><affiliation wicri:level="1"><nlm:affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author><author><name sortKey="Tong, Jian Ning" sort="Tong, Jian Ning" uniqKey="Tong J" first="Jian-Ning" last="Tong">Jian-Ning Tong</name><affiliation wicri:level="1"><nlm:affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author><author><name sortKey="Song, Xiu Feng" sort="Song, Xiu Feng" uniqKey="Song X" first="Xiu-Feng" last="Song">Xiu-Feng Song</name><affiliation wicri:level="1"><nlm:affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author><author><name sortKey="Wing Kin Wong, Gary" sort="Wing Kin Wong, Gary" uniqKey="Wing Kin Wong G" first="Gary" last="Wing-Kin Wong">Gary Wing-Kin Wong</name><affiliation wicri:level="4"><nlm:affiliation>Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: wingkinwong@cuhk.edu.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Xing, Quan Sheng" sort="Xing, Quan Sheng" uniqKey="Xing Q" first="Quan-Sheng" last="Xing">Quan-Sheng Xing</name><affiliation wicri:level="1"><nlm:affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China. Electronic address: xingqs0532@163.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province</wicri:regionArea><wicri:noRegion>Shandong Province</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</title><idno type="eISSN">1995-9133</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19).</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32276848</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>14</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1995-9133</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Mar</Month><Day>28</Day></PubDate></JournalIssue><Title>Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi</Title><ISOAbbreviation>J Microbiol Immunol Infect</ISOAbbreviation></Journal><ArticleTitle>Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">S1684-1182(20)30081-5</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jmii.2020.03.021</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">From January 17, 2020 to February 23, 2020, three paediatric cases of COVID-19 were reported in Qingdao, Shandong Province, China. Epidemiological, clinical, laboratory, and radiological characteristics and treatment data were collected. Patients were followed up to March 10, 2020, and dynamic profiles of nucleic acid testing results in throat swabs and fecal specimens were closely monitored.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Clearance of SARS-CoV-2 in respiratory tract occurred within two weeks after abatement of fever, whereas viral RNA remained detectable in stools of pediatric patients for longer than 4 weeks. Two children had fecal SARS-CoV-2 undetectable 20 days after throat swabs showing negative, while that of another child lagged behind for 8 days.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">SARS-CoV-2 may exist in children's gastrointestinal tract for a longer time than respiratory system. Persistent shedding of SARS-CoV-2 in stools of infected children raises the possibility that the virus might be transmitted through contaminated fomites. Massive efforts should be made at all levels to prevent spreading of the infection among children after reopening of kindergartens and schools.</AbstractText><CopyrightInformation>Copyright © 2020. Published by Elsevier B.V.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Xing</LastName><ForeName>Yu-Han</ForeName><Initials>YH</Initials><AffiliationInfo><Affiliation>Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ni</LastName><ForeName>Wei</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wu</LastName><ForeName>Qin</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Wen-Jie</ForeName><Initials>WJ</Initials><AffiliationInfo><Affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Guo-Ju</ForeName><Initials>GJ</Initials><AffiliationInfo><Affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Wen-Di</ForeName><Initials>WD</Initials><AffiliationInfo><Affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tong</LastName><ForeName>Jian-Ning</ForeName><Initials>JN</Initials><AffiliationInfo><Affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Song</LastName><ForeName>Xiu-Feng</ForeName><Initials>XF</Initials><AffiliationInfo><Affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wing-Kin Wong</LastName><ForeName>Gary</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Department of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China. Electronic address: wingkinwong@cuhk.edu.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xing</LastName><ForeName>Quan-Sheng</ForeName><Initials>QS</Initials><AffiliationInfo><Affiliation>Qingdao Women and Children's Hospital, Qingdao University, Qingdao, Shandong Province, China. Electronic address: xingqs0532@163.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>28</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Microbiol Immunol Infect</MedlineTA><NlmUniqueID>100956211</NlmUniqueID><ISSNLinking>1684-1182</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Fecal shedding</Keyword><Keyword MajorTopicYN="N">Pediatric patient</Keyword><Keyword MajorTopicYN="N">SARS-CoV-2</Keyword></KeywordList><CoiStatement>Declaration of Competing Interest None reported.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>03</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>03</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>03</Month><Day>25</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>4</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>4</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32276848</ArticleId><ArticleId IdType="pii">S1684-1182(20)30081-5</ArticleId><ArticleId IdType="doi">10.1016/j.jmii.2020.03.021</ArticleId><ArticleId 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Tin</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Xing, Yu Han" sort="Xing, Yu Han" uniqKey="Xing Y" first="Yu-Han" last="Xing">Yu-Han Xing</name></noRegion><name sortKey="Li, Guo Ju" sort="Li, Guo Ju" uniqKey="Li G" first="Guo-Ju" last="Li">Guo-Ju Li</name><name sortKey="Li, Wen Jie" sort="Li, Wen Jie" uniqKey="Li W" first="Wen-Jie" last="Li">Wen-Jie Li</name><name sortKey="Ni, Wei" sort="Ni, Wei" uniqKey="Ni W" first="Wei" last="Ni">Wei Ni</name><name sortKey="Song, Xiu Feng" sort="Song, Xiu Feng" uniqKey="Song X" first="Xiu-Feng" last="Song">Xiu-Feng Song</name><name sortKey="Tong, Jian Ning" sort="Tong, Jian Ning" uniqKey="Tong J" first="Jian-Ning" last="Tong">Jian-Ning Tong</name><name sortKey="Wang, Wen Di" sort="Wang, Wen Di" uniqKey="Wang W" first="Wen-Di" last="Wang">Wen-Di Wang</name><name sortKey="Wing Kin Wong, Gary" sort="Wing Kin Wong, Gary" uniqKey="Wing Kin Wong G" first="Gary" last="Wing-Kin Wong">Gary Wing-Kin Wong</name><name sortKey="Wu, Qin" sort="Wu, Qin" uniqKey="Wu Q" first="Qin" last="Wu">Qin Wu</name><name sortKey="Xing, Quan Sheng" sort="Xing, Quan Sheng" uniqKey="Xing Q" first="Quan-Sheng" last="Xing">Quan-Sheng Xing</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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