COVID-19 Autopsies, Oklahoma, USA.
Identifieur interne : 003877 ( Ncbi/Merge ); précédent : 003876; suivant : 003878COVID-19 Autopsies, Oklahoma, USA.
Auteurs : Lisa M. Barton [États-Unis] ; Eric J. Duval [États-Unis] ; Edana Stroberg [États-Unis] ; Subha Ghosh [États-Unis] ; Sanjay Mukhopadhyay [États-Unis]Source :
- American journal of clinical pathology [ 1943-7722 ] ; 2020.
Abstract
To report the methods and findings of two complete autopsies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive individuals who died in Oklahoma (United States) in March 2020.
DOI: 10.1093/ajcp/aqaa062
PubMed: 32275742
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Duval</name><affiliation wicri:level="2"><nlm:affiliation>Office of the Chief Medical Examiner, Oklahoma City, OK.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>Office of the Chief Medical Examiner, Oklahoma City</wicri:cityArea></affiliation></author><author><name sortKey="Stroberg, Edana" sort="Stroberg, Edana" uniqKey="Stroberg E" first="Edana" last="Stroberg">Edana Stroberg</name><affiliation wicri:level="2"><nlm:affiliation>Office of the Chief Medical Examiner, Oklahoma City, OK.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>Office of the Chief Medical Examiner, Oklahoma City</wicri:cityArea></affiliation></author><author><name sortKey="Ghosh, Subha" sort="Ghosh, Subha" uniqKey="Ghosh S" first="Subha" last="Ghosh">Subha Ghosh</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Cleveland Clinic, Cleveland, OH.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Pathology, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Mukhopadhyay, Sanjay" sort="Mukhopadhyay, Sanjay" uniqKey="Mukhopadhyay S" first="Sanjay" last="Mukhopadhyay">Sanjay Mukhopadhyay</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Cleveland Clinic, Cleveland, OH.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Pathology, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32275742</idno><idno type="pmid">32275742</idno><idno type="doi">10.1093/ajcp/aqaa062</idno><idno type="wicri:Area/PubMed/Corpus">000235</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000235</idno><idno type="wicri:Area/PubMed/Curation">000235</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000235</idno><idno type="wicri:Area/PubMed/Checkpoint">000756</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000756</idno><idno type="wicri:Area/Ncbi/Merge">003877</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">COVID-19 Autopsies, Oklahoma, USA.</title><author><name sortKey="Barton, Lisa M" sort="Barton, Lisa M" uniqKey="Barton L" first="Lisa M" last="Barton">Lisa M. Barton</name><affiliation wicri:level="2"><nlm:affiliation>Office of the Chief Medical Examiner, Oklahoma City, OK.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>Office of the Chief Medical Examiner, Oklahoma City</wicri:cityArea></affiliation></author><author><name sortKey="Duval, Eric J" sort="Duval, Eric J" uniqKey="Duval E" first="Eric J" last="Duval">Eric J. Duval</name><affiliation wicri:level="2"><nlm:affiliation>Office of the Chief Medical Examiner, Oklahoma City, OK.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>Office of the Chief Medical Examiner, Oklahoma City</wicri:cityArea></affiliation></author><author><name sortKey="Stroberg, Edana" sort="Stroberg, Edana" uniqKey="Stroberg E" first="Edana" last="Stroberg">Edana Stroberg</name><affiliation wicri:level="2"><nlm:affiliation>Office of the Chief Medical Examiner, Oklahoma City, OK.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Oklahoma</region></placeName><wicri:cityArea>Office of the Chief Medical Examiner, Oklahoma City</wicri:cityArea></affiliation></author><author><name sortKey="Ghosh, Subha" sort="Ghosh, Subha" uniqKey="Ghosh S" first="Subha" last="Ghosh">Subha Ghosh</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Cleveland Clinic, Cleveland, OH.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Pathology, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author><author><name sortKey="Mukhopadhyay, Sanjay" sort="Mukhopadhyay, Sanjay" uniqKey="Mukhopadhyay S" first="Sanjay" last="Mukhopadhyay">Sanjay Mukhopadhyay</name><affiliation wicri:level="2"><nlm:affiliation>Department of Pathology, Cleveland Clinic, Cleveland, OH.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Ohio</region></placeName><wicri:cityArea>Department of Pathology, Cleveland Clinic, Cleveland</wicri:cityArea></affiliation></author></analytic><series><title level="j">American journal of clinical pathology</title><idno type="eISSN">1943-7722</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To report the methods and findings of two complete autopsies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive individuals who died in Oklahoma (United States) in March 2020.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32275742</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>10</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1943-7722</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Apr</Month><Day>10</Day></PubDate></JournalIssue><Title>American journal of clinical pathology</Title><ISOAbbreviation>Am. J. Clin. Pathol.</ISOAbbreviation></Journal><ArticleTitle>COVID-19 Autopsies, Oklahoma, USA.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">aqaa062</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1093/ajcp/aqaa062</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To report the methods and findings of two complete autopsies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive individuals who died in Oklahoma (United States) in March 2020.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Complete postmortem examinations were performed according to standard procedures in a negative-pressure autopsy suite/isolation room using personal protective equipment, including N95 masks, eye protection, and gowns. The diagnosis of coronavirus disease 2019 (COVID-19) was confirmed by real-time reverse transcriptase polymerase chain reaction testing on postmortem swabs.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A 77-year-old obese man with a history of hypertension, splenectomy, and 6 days of fever and chills died while being transported for medical care. He tested positive for SARS-CoV-2 on postmortem nasopharyngeal and lung parenchymal swabs. Autopsy revealed diffuse alveolar damage and chronic inflammation and edema in the bronchial mucosa. A 42-year-old obese man with a history of myotonic dystrophy developed abdominal pain followed by fever, shortness of breath, and cough. Postmortem nasopharyngeal swab was positive for SARS-CoV-2; lung parenchymal swabs were negative. Autopsy showed acute bronchopneumonia with evidence of aspiration. Neither autopsy revealed viral inclusions, mucus plugging in airways, eosinophils, or myocarditis.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">SARS-CoV-2 testing can be performed at autopsy. Autopsy findings such as diffuse alveolar damage and airway inflammation reflect true virus-related pathology; other findings represent superimposed or unrelated processes.</AbstractText><CopyrightInformation>© American Society for Clinical Pathology, 2020. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Barton</LastName><ForeName>Lisa M</ForeName><Initials>LM</Initials><AffiliationInfo><Affiliation>Office of the Chief Medical Examiner, Oklahoma City, OK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Duval</LastName><ForeName>Eric J</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>Office of the Chief Medical Examiner, Oklahoma City, OK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stroberg</LastName><ForeName>Edana</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Office of the Chief Medical Examiner, Oklahoma City, OK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ghosh</LastName><ForeName>Subha</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pathology, Cleveland Clinic, Cleveland, OH.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mukhopadhyay</LastName><ForeName>Sanjay</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pathology, Cleveland Clinic, Cleveland, OH.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>04</Month><Day>10</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Am J Clin Pathol</MedlineTA><NlmUniqueID>0370470</NlmUniqueID><ISSNLinking>0002-9173</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Acute lung injury</Keyword><Keyword MajorTopicYN="N">Autopsy</Keyword><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Coronavirus</Keyword><Keyword MajorTopicYN="N">Diffuse alveolar damage</Keyword><Keyword MajorTopicYN="N">Pulmonary pathology</Keyword><Keyword MajorTopicYN="N">SARS-CoV-2</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>4</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>4</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32275742</ArticleId><ArticleId IdType="pii">5818922</ArticleId><ArticleId IdType="doi">10.1093/ajcp/aqaa062</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Ohio</li><li>Oklahoma</li></region></list><tree><country name="États-Unis"><region name="Oklahoma"><name sortKey="Barton, Lisa M" sort="Barton, Lisa M" uniqKey="Barton L" first="Lisa M" last="Barton">Lisa M. Barton</name></region><name sortKey="Duval, Eric J" sort="Duval, Eric J" uniqKey="Duval E" first="Eric J" last="Duval">Eric J. Duval</name><name sortKey="Ghosh, Subha" sort="Ghosh, Subha" uniqKey="Ghosh S" first="Subha" last="Ghosh">Subha Ghosh</name><name sortKey="Mukhopadhyay, Sanjay" sort="Mukhopadhyay, Sanjay" uniqKey="Mukhopadhyay S" first="Sanjay" last="Mukhopadhyay">Sanjay Mukhopadhyay</name><name sortKey="Stroberg, Edana" sort="Stroberg, Edana" uniqKey="Stroberg E" first="Edana" last="Stroberg">Edana Stroberg</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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