Covid-19 in Critically Ill Patients in the Seattle Region - Case Series.
Identifieur interne : 003636 ( Ncbi/Merge ); précédent : 003635; suivant : 003637Covid-19 in Critically Ill Patients in the Seattle Region - Case Series.
Auteurs : Pavan K. Bhatraju [États-Unis] ; Bijan J. Ghassemieh [États-Unis] ; Michelle Nichols [États-Unis] ; Richard Kim [États-Unis] ; Keith R. Jerome [États-Unis] ; Arun K. Nalla [États-Unis] ; Alexander L. Greninger [États-Unis] ; Sudhakar Pipavath [États-Unis] ; Mark M. Wurfel [États-Unis] ; Laura Evans [États-Unis] ; Patricia A. Kritek [États-Unis] ; T Eoin West [États-Unis] ; Andrew Luks [États-Unis] ; Anthony Gerbino [États-Unis] ; Chris R. Dale [États-Unis] ; Jason D. Goldman [États-Unis] ; Shane O'Mahony [États-Unis] ; Carmen Mikacenic [États-Unis]Source :
- The New England journal of medicine [ 1533-4406 ] ; 2020.
Abstract
Community transmission of coronavirus 2019 (Covid-19) was detected in the state of Washington in February 2020.
DOI: 10.1056/NEJMoa2004500
PubMed: 32227758
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Covid-19 in Critically Ill Patients in the Seattle Region - Case Series.</title><author><name sortKey="Bhatraju, Pavan K" sort="Bhatraju, Pavan K" uniqKey="Bhatraju P" first="Pavan K" last="Bhatraju">Pavan K. Bhatraju</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Ghassemieh, Bijan J" sort="Ghassemieh, Bijan J" uniqKey="Ghassemieh B" first="Bijan J" last="Ghassemieh">Bijan J. Ghassemieh</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Nichols, Michelle" sort="Nichols, Michelle" uniqKey="Nichols M" first="Michelle" last="Nichols">Michelle Nichols</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kim, Richard" sort="Kim, Richard" uniqKey="Kim R" first="Richard" last="Kim">Richard Kim</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Jerome, Keith R" sort="Jerome, Keith R" uniqKey="Jerome K" first="Keith R" last="Jerome">Keith R. Jerome</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Nalla, Arun K" sort="Nalla, Arun K" uniqKey="Nalla A" first="Arun K" last="Nalla">Arun K. Nalla</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Greninger, Alexander L" sort="Greninger, Alexander L" uniqKey="Greninger A" first="Alexander L" last="Greninger">Alexander L. Greninger</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Pipavath, Sudhakar" sort="Pipavath, Sudhakar" uniqKey="Pipavath S" first="Sudhakar" last="Pipavath">Sudhakar Pipavath</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Wurfel, Mark M" sort="Wurfel, Mark M" uniqKey="Wurfel M" first="Mark M" last="Wurfel">Mark M. Wurfel</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Evans, Laura" sort="Evans, Laura" uniqKey="Evans L" first="Laura" last="Evans">Laura Evans</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kritek, Patricia A" sort="Kritek, Patricia A" uniqKey="Kritek P" first="Patricia A" last="Kritek">Patricia A. Kritek</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="West, T Eoin" sort="West, T Eoin" uniqKey="West T" first="T Eoin" last="West">T Eoin West</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Luks, Andrew" sort="Luks, Andrew" uniqKey="Luks A" first="Andrew" last="Luks">Andrew Luks</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Gerbino, Anthony" sort="Gerbino, Anthony" uniqKey="Gerbino A" first="Anthony" last="Gerbino">Anthony Gerbino</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Dale, Chris R" sort="Dale, Chris R" uniqKey="Dale C" first="Chris R" last="Dale">Chris R. Dale</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Goldman, Jason D" sort="Goldman, Jason D" uniqKey="Goldman J" first="Jason D" last="Goldman">Jason D. Goldman</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="O Mahony, Shane" sort="O Mahony, Shane" uniqKey="O Mahony S" first="Shane" last="O'Mahony">Shane O'Mahony</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mikacenic, Carmen" sort="Mikacenic, Carmen" uniqKey="Mikacenic C" first="Carmen" last="Mikacenic">Carmen Mikacenic</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32227758</idno><idno type="pmid">32227758</idno><idno type="doi">10.1056/NEJMoa2004500</idno><idno type="wicri:Area/PubMed/Corpus">000454</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000454</idno><idno type="wicri:Area/PubMed/Curation">000454</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000454</idno><idno type="wicri:Area/PubMed/Checkpoint">000592</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000592</idno><idno type="wicri:Area/Ncbi/Merge">003636</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Covid-19 in Critically Ill Patients in the Seattle Region - Case Series.</title><author><name sortKey="Bhatraju, Pavan K" sort="Bhatraju, Pavan K" uniqKey="Bhatraju P" first="Pavan K" last="Bhatraju">Pavan K. Bhatraju</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Ghassemieh, Bijan J" sort="Ghassemieh, Bijan J" uniqKey="Ghassemieh B" first="Bijan J" last="Ghassemieh">Bijan J. Ghassemieh</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Nichols, Michelle" sort="Nichols, Michelle" uniqKey="Nichols M" first="Michelle" last="Nichols">Michelle Nichols</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kim, Richard" sort="Kim, Richard" uniqKey="Kim R" first="Richard" last="Kim">Richard Kim</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Jerome, Keith R" sort="Jerome, Keith R" uniqKey="Jerome K" first="Keith R" last="Jerome">Keith R. Jerome</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Nalla, Arun K" sort="Nalla, Arun K" uniqKey="Nalla A" first="Arun K" last="Nalla">Arun K. Nalla</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Greninger, Alexander L" sort="Greninger, Alexander L" uniqKey="Greninger A" first="Alexander L" last="Greninger">Alexander L. Greninger</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Pipavath, Sudhakar" sort="Pipavath, Sudhakar" uniqKey="Pipavath S" first="Sudhakar" last="Pipavath">Sudhakar Pipavath</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Wurfel, Mark M" sort="Wurfel, Mark M" uniqKey="Wurfel M" first="Mark M" last="Wurfel">Mark M. Wurfel</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Evans, Laura" sort="Evans, Laura" uniqKey="Evans L" first="Laura" last="Evans">Laura Evans</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Kritek, Patricia A" sort="Kritek, Patricia A" uniqKey="Kritek P" first="Patricia A" last="Kritek">Patricia A. Kritek</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="West, T Eoin" sort="West, T Eoin" uniqKey="West T" first="T Eoin" last="West">T Eoin West</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Luks, Andrew" sort="Luks, Andrew" uniqKey="Luks A" first="Andrew" last="Luks">Andrew Luks</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Gerbino, Anthony" sort="Gerbino, Anthony" uniqKey="Gerbino A" first="Anthony" last="Gerbino">Anthony Gerbino</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Dale, Chris R" sort="Dale, Chris R" uniqKey="Dale C" first="Chris R" last="Dale">Chris R. Dale</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Goldman, Jason D" sort="Goldman, Jason D" uniqKey="Goldman J" first="Jason D" last="Goldman">Jason D. Goldman</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="O Mahony, Shane" sort="O Mahony, Shane" uniqKey="O Mahony S" first="Shane" last="O'Mahony">Shane O'Mahony</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Mikacenic, Carmen" sort="Mikacenic, Carmen" uniqKey="Mikacenic C" first="Carmen" last="Mikacenic">Carmen Mikacenic</name><affiliation wicri:level="4"><nlm:affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</nlm:affiliation><orgName type="university">Université de Washington</orgName><country>États-Unis</country><placeName><settlement type="city">Seattle</settlement><region type="state">Washington (État)</region></placeName></affiliation></author></analytic><series><title level="j">The New England journal of medicine</title><idno type="eISSN">1533-4406</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Community transmission of coronavirus 2019 (Covid-19) was detected in the state of Washington in February 2020.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32227758</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>16</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1533-4406</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Mar</Month><Day>30</Day></PubDate></JournalIssue><Title>The New England journal of medicine</Title><ISOAbbreviation>N. Engl. J. Med.</ISOAbbreviation></Journal><ArticleTitle>Covid-19 in Critically Ill Patients in the Seattle Region - Case Series.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1056/NEJMoa2004500</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Community transmission of coronavirus 2019 (Covid-19) was detected in the state of Washington in February 2020.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We identified patients from nine Seattle-area hospitals who were admitted to the intensive care unit (ICU) with confirmed infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Clinical data were obtained through review of medical records. The data reported here are those available through March 23, 2020. Each patient had at least 14 days of follow-up.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">We identified 24 patients with confirmed Covid-19. The mean (±SD) age of the patients was 64±18 years, 63% were men, and symptoms began 7±4 days before admission. The most common symptoms were cough and shortness of breath; 50% of patients had fever on admission, and 58% had diabetes mellitus. All the patients were admitted for hypoxemic respiratory failure; 75% (18 patients) needed mechanical ventilation. Most of the patients (17) also had hypotension and needed vasopressors. No patient tested positive for influenza A, influenza B, or other respiratory viruses. Half the patients (12) died between ICU day 1 and day 18, including 4 patients who had a do-not-resuscitate order on admission. Of the 12 surviving patients, 5 were discharged home, 4 were discharged from the ICU but remained in the hospital, and 3 continued to receive mechanical ventilation in the ICU.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">During the first 3 weeks of the Covid-19 outbreak in the Seattle area, the most common reasons for admission to the ICU were hypoxemic respiratory failure leading to mechanical ventilation, hypotension requiring vasopressor treatment, or both. Mortality among these critically ill patients was high. (Funded by the National Institutes of Health.).</AbstractText><CopyrightInformation>Copyright © 2020 Massachusetts Medical Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bhatraju</LastName><ForeName>Pavan K</ForeName><Initials>PK</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ghassemieh</LastName><ForeName>Bijan J</ForeName><Initials>BJ</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nichols</LastName><ForeName>Michelle</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Richard</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jerome</LastName><ForeName>Keith R</ForeName><Initials>KR</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nalla</LastName><ForeName>Arun K</ForeName><Initials>AK</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Greninger</LastName><ForeName>Alexander L</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pipavath</LastName><ForeName>Sudhakar</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wurfel</LastName><ForeName>Mark M</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Evans</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kritek</LastName><ForeName>Patricia A</ForeName><Initials>PA</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>West</LastName><ForeName>T Eoin</ForeName><Initials>TE</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luks</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gerbino</LastName><ForeName>Anthony</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dale</LastName><ForeName>Chris R</ForeName><Initials>CR</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Goldman</LastName><ForeName>Jason D</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>O'Mahony</LastName><ForeName>Shane</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mikacenic</LastName><ForeName>Carmen</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0001-8966-5161</Identifier><AffiliationInfo><Affiliation>From the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine (P.K.B., B.J.G., M.N., R.K., M.M.W., L.E., P.A.K., T.E.W., A.L., C.M.), the Departments of Laboratory Medicine (K.R.J., A.K.N., A.L.G.) and Radiology (S.P.), and the Division of Allergy and Infectious Disease (J.D.G.), University of Washington, the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (K.R.J., A.K.N., A.L.G.), the Sections of Critical Care and Pulmonary Medicine, Virginia Mason Medical Center (A.G.), and the Divisions of Pulmonary and Critical Care (C.R.D., S.O.) and Infectious Disease (J.D.G.), Swedish Medical Center - all in Seattle.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>K23 DK116967</GrantID><Acronym>DK</Acronym><Agency>NIDDK NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>30</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>N Engl J Med</MedlineTA><NlmUniqueID>0255562</NlmUniqueID><ISSNLinking>0028-4793</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>4</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate 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de Washington</li></orgName></list><tree><country name="États-Unis"><region name="Washington (État)"><name sortKey="Bhatraju, Pavan K" sort="Bhatraju, Pavan K" uniqKey="Bhatraju P" first="Pavan K" last="Bhatraju">Pavan K. Bhatraju</name></region><name sortKey="Dale, Chris R" sort="Dale, Chris R" uniqKey="Dale C" first="Chris R" last="Dale">Chris R. Dale</name><name sortKey="Evans, Laura" sort="Evans, Laura" uniqKey="Evans L" first="Laura" last="Evans">Laura Evans</name><name sortKey="Gerbino, Anthony" sort="Gerbino, Anthony" uniqKey="Gerbino A" first="Anthony" last="Gerbino">Anthony Gerbino</name><name sortKey="Ghassemieh, Bijan J" sort="Ghassemieh, Bijan J" uniqKey="Ghassemieh B" first="Bijan J" last="Ghassemieh">Bijan J. Ghassemieh</name><name sortKey="Goldman, Jason D" sort="Goldman, Jason D" uniqKey="Goldman J" first="Jason D" last="Goldman">Jason D. Goldman</name><name sortKey="Greninger, Alexander L" sort="Greninger, Alexander L" uniqKey="Greninger A" first="Alexander L" last="Greninger">Alexander L. Greninger</name><name sortKey="Jerome, Keith R" sort="Jerome, Keith R" uniqKey="Jerome K" first="Keith R" last="Jerome">Keith R. Jerome</name><name sortKey="Kim, Richard" sort="Kim, Richard" uniqKey="Kim R" first="Richard" last="Kim">Richard Kim</name><name sortKey="Kritek, Patricia A" sort="Kritek, Patricia A" uniqKey="Kritek P" first="Patricia A" last="Kritek">Patricia A. Kritek</name><name sortKey="Luks, Andrew" sort="Luks, Andrew" uniqKey="Luks A" first="Andrew" last="Luks">Andrew Luks</name><name sortKey="Mikacenic, Carmen" sort="Mikacenic, Carmen" uniqKey="Mikacenic C" first="Carmen" last="Mikacenic">Carmen Mikacenic</name><name sortKey="Nalla, Arun K" sort="Nalla, Arun K" uniqKey="Nalla A" first="Arun K" last="Nalla">Arun K. Nalla</name><name sortKey="Nichols, Michelle" sort="Nichols, Michelle" uniqKey="Nichols M" first="Michelle" last="Nichols">Michelle Nichols</name><name sortKey="O Mahony, Shane" sort="O Mahony, Shane" uniqKey="O Mahony S" first="Shane" last="O'Mahony">Shane O'Mahony</name><name sortKey="Pipavath, Sudhakar" sort="Pipavath, Sudhakar" uniqKey="Pipavath S" first="Sudhakar" last="Pipavath">Sudhakar Pipavath</name><name sortKey="West, T Eoin" sort="West, T Eoin" uniqKey="West T" first="T Eoin" last="West">T Eoin West</name><name sortKey="Wurfel, Mark M" sort="Wurfel, Mark M" uniqKey="Wurfel M" first="Mark M" last="Wurfel">Mark M. Wurfel</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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