Cost-effectiveness Analysis of Hospital Infection Control Response to an Epidemic Respiratory Virus Threat
Identifieur interne : 002041 ( Ncbi/Merge ); précédent : 002040; suivant : 002042Cost-effectiveness Analysis of Hospital Infection Control Response to an Epidemic Respiratory Virus Threat
Auteurs : Yock Young Dan ; Paul A. Tambyah ; Joe Sim ; Jeremy Lim ; Li Yang Hsu ; Wai Leng Chow ; Dale A. Fisher ; Yue Sie Wong ; Khek Yu HoSource :
- Emerging Infectious Diseases [ 1080-6040 ] ; 2009.
Descripteurs français
- KwdFr :
- MESH :
- Wicri :
- geographic : Singapour.
English descriptors
- KwdEn :
- Cost-Benefit Analysis, Cross Infection (prevention & control), Disease Outbreaks, Humans, Influenza A Virus, H1N1 Subtype, Influenza, Human (epidemiology), Influenza, Human (prevention & control), Markov Chains, Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (prevention & control), Singapore.
- MESH :
- geographic : Singapore.
- epidemiology : Influenza, Human, Severe Acute Respiratory Syndrome.
- prevention & control : Cross Infection, Influenza, Human, Severe Acute Respiratory Syndrome.
- Cost-Benefit Analysis, Disease Outbreaks, Humans, Influenza A Virus, H1N1 Subtype, Markov Chains.
Abstract
Pandemic (H1N1) 2009 can be contained with less expensive measures than some other viruses.
Url:
DOI: 10.3201/eid1512.090902
PubMed: 19961669
PubMed Central: 3044543
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PMC:3044543Le document en format XML
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Fisher</name></author><author><name sortKey="Wong, Yue Sie" sort="Wong, Yue Sie" uniqKey="Wong Y" first="Yue Sie" last="Wong">Yue Sie Wong</name></author><author><name sortKey="Ho, Khek Yu" sort="Ho, Khek Yu" uniqKey="Ho K" first="Khek Yu" last="Ho">Khek Yu Ho</name></author></analytic><series><title level="j">Emerging Infectious Diseases</title><idno type="ISSN">1080-6040</idno><idno type="eISSN">1080-6059</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cost-Benefit Analysis</term><term>Cross Infection (prevention & control)</term><term>Disease Outbreaks</term><term>Humans</term><term>Influenza A Virus, H1N1 Subtype</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (prevention & control)</term><term>Markov Chains</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (prevention & control)</term><term>Singapore</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analyse coût-bénéfice</term><term>Chaines de Markov</term><term>Flambées de maladies</term><term>Grippe humaine ()</term><term>Grippe humaine (épidémiologie)</term><term>Humains</term><term>Infection croisée ()</term><term>Singapour</term><term>Sous-type H1N1 du virus de la grippe A</term><term>Syndrome respiratoire aigu sévère ()</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Singapore</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cross Infection</term><term>Influenza, Human</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Grippe humaine</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cost-Benefit Analysis</term><term>Disease Outbreaks</term><term>Humans</term><term>Influenza A Virus, H1N1 Subtype</term><term>Markov Chains</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse coût-bénéfice</term><term>Chaines de Markov</term><term>Flambées de maladies</term><term>Grippe humaine</term><term>Humains</term><term>Infection croisée</term><term>Singapour</term><term>Sous-type H1N1 du virus de la grippe A</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Singapour</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Pandemic (H1N1) 2009 can be contained with less expensive measures than some other viruses.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><double pmid="19961669"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cost-effectiveness Analysis of Hospital Infection Control Response to an Epidemic Respiratory Virus Threat</title><author><name sortKey="Dan, Yock Young" sort="Dan, Yock Young" uniqKey="Dan Y" first="Yock Young" last="Dan">Yock Young Dan</name></author><author><name sortKey="Tambyah, Paul A" sort="Tambyah, Paul A" uniqKey="Tambyah P" first="Paul A." last="Tambyah">Paul A. Tambyah</name></author><author><name sortKey="Sim, Joe" sort="Sim, Joe" uniqKey="Sim J" first="Joe" last="Sim">Joe Sim</name></author><author><name sortKey="Lim, Jeremy" sort="Lim, Jeremy" uniqKey="Lim J" first="Jeremy" last="Lim">Jeremy Lim</name></author><author><name sortKey="Hsu, Li Yang" sort="Hsu, Li Yang" uniqKey="Hsu L" first="Li Yang" last="Hsu">Li Yang Hsu</name></author><author><name sortKey="Chow, Wai Leng" sort="Chow, Wai Leng" uniqKey="Chow W" first="Wai Leng" last="Chow">Wai Leng Chow</name></author><author><name sortKey="Fisher, Dale A" sort="Fisher, Dale A" uniqKey="Fisher D" first="Dale A." last="Fisher">Dale A. Fisher</name></author><author><name sortKey="Wong, Yue Sie" sort="Wong, Yue Sie" uniqKey="Wong Y" first="Yue Sie" last="Wong">Yue Sie Wong</name></author><author><name sortKey="Ho, Khek Yu" sort="Ho, Khek Yu" uniqKey="Ho K" first="Khek Yu" last="Ho">Khek Yu Ho</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">19961669</idno><idno type="pmc">3044543</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044543</idno><idno type="RBID">PMC:3044543</idno><idno type="doi">10.3201/eid1512.090902</idno><date when="2009">2009</date><idno type="wicri:Area/Pmc/Corpus">000F74</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000F74</idno><idno type="wicri:Area/Pmc/Curation">000F74</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000F74</idno><idno type="wicri:Area/Pmc/Checkpoint">000D36</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000D36</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Cost-effectiveness Analysis of Hospital Infection Control Response to an Epidemic Respiratory Virus Threat</title><author><name sortKey="Dan, Yock Young" sort="Dan, Yock Young" uniqKey="Dan Y" first="Yock Young" last="Dan">Yock Young Dan</name></author><author><name sortKey="Tambyah, Paul A" sort="Tambyah, Paul A" uniqKey="Tambyah P" first="Paul A." last="Tambyah">Paul A. Tambyah</name></author><author><name sortKey="Sim, Joe" sort="Sim, Joe" uniqKey="Sim J" first="Joe" last="Sim">Joe Sim</name></author><author><name sortKey="Lim, Jeremy" sort="Lim, Jeremy" uniqKey="Lim J" first="Jeremy" last="Lim">Jeremy Lim</name></author><author><name sortKey="Hsu, Li Yang" sort="Hsu, Li Yang" uniqKey="Hsu L" first="Li Yang" last="Hsu">Li Yang Hsu</name></author><author><name sortKey="Chow, Wai Leng" sort="Chow, Wai Leng" uniqKey="Chow W" first="Wai Leng" last="Chow">Wai Leng Chow</name></author><author><name sortKey="Fisher, Dale A" sort="Fisher, Dale A" uniqKey="Fisher D" first="Dale A." last="Fisher">Dale A. Fisher</name></author><author><name sortKey="Wong, Yue Sie" sort="Wong, Yue Sie" uniqKey="Wong Y" first="Yue Sie" last="Wong">Yue Sie Wong</name></author><author><name sortKey="Ho, Khek Yu" sort="Ho, Khek Yu" uniqKey="Ho K" first="Khek Yu" last="Ho">Khek Yu Ho</name></author></analytic><series><title level="j">Emerging Infectious Diseases</title><idno type="ISSN">1080-6040</idno><idno type="eISSN">1080-6059</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Pandemic (H1N1) 2009 can be contained with less expensive measures than some other viruses.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI></pmc><pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Cost-effectiveness analysis of hospital infection control response to an epidemic respiratory virus threat.</title><author><name sortKey="Dan, Yock Young" sort="Dan, Yock Young" uniqKey="Dan Y" first="Yock Young" last="Dan">Yock Young Dan</name><affiliation wicri:level="1"><nlm:affiliation>National University Health System, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>National University Health System</wicri:regionArea></affiliation></author><author><name sortKey="Tambyah, Paul A" sort="Tambyah, Paul A" uniqKey="Tambyah P" first="Paul A" last="Tambyah">Paul A. Tambyah</name></author><author><name sortKey="Sim, Joe" sort="Sim, Joe" uniqKey="Sim J" first="Joe" last="Sim">Joe Sim</name></author><author><name sortKey="Lim, Jeremy" sort="Lim, Jeremy" uniqKey="Lim J" first="Jeremy" last="Lim">Jeremy Lim</name></author><author><name sortKey="Hsu, Li Yang" sort="Hsu, Li Yang" uniqKey="Hsu L" first="Li Yang" last="Hsu">Li Yang Hsu</name></author><author><name sortKey="Chow, Wai Leng" sort="Chow, Wai Leng" uniqKey="Chow W" first="Wai Leng" last="Chow">Wai Leng Chow</name></author><author><name sortKey="Fisher, Dale A" sort="Fisher, Dale A" uniqKey="Fisher D" first="Dale A" last="Fisher">Dale A. Fisher</name></author><author><name sortKey="Wong, Yue Sie" sort="Wong, Yue Sie" uniqKey="Wong Y" first="Yue Sie" last="Wong">Yue Sie Wong</name></author><author><name sortKey="Ho, Khek Yu" sort="Ho, Khek Yu" uniqKey="Ho K" first="Khek Yu" last="Ho">Khek Yu Ho</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:19961669</idno><idno type="pmid">19961669</idno><idno type="doi">10.3201/eid1512.090902</idno><idno type="wicri:Area/PubMed/Corpus">001784</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001784</idno><idno type="wicri:Area/PubMed/Curation">001784</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001784</idno><idno type="wicri:Area/PubMed/Checkpoint">001913</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001913</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Cost-effectiveness analysis of hospital infection control response to an epidemic respiratory virus threat.</title><author><name sortKey="Dan, Yock Young" sort="Dan, Yock Young" uniqKey="Dan Y" first="Yock Young" last="Dan">Yock Young Dan</name><affiliation wicri:level="1"><nlm:affiliation>National University Health System, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>National University Health System</wicri:regionArea></affiliation></author><author><name sortKey="Tambyah, Paul A" sort="Tambyah, Paul A" uniqKey="Tambyah P" first="Paul A" last="Tambyah">Paul A. Tambyah</name></author><author><name sortKey="Sim, Joe" sort="Sim, Joe" uniqKey="Sim J" first="Joe" last="Sim">Joe Sim</name></author><author><name sortKey="Lim, Jeremy" sort="Lim, Jeremy" uniqKey="Lim J" first="Jeremy" last="Lim">Jeremy Lim</name></author><author><name sortKey="Hsu, Li Yang" sort="Hsu, Li Yang" uniqKey="Hsu L" first="Li Yang" last="Hsu">Li Yang Hsu</name></author><author><name sortKey="Chow, Wai Leng" sort="Chow, Wai Leng" uniqKey="Chow W" first="Wai Leng" last="Chow">Wai Leng Chow</name></author><author><name sortKey="Fisher, Dale A" sort="Fisher, Dale A" uniqKey="Fisher D" first="Dale A" last="Fisher">Dale A. Fisher</name></author><author><name sortKey="Wong, Yue Sie" sort="Wong, Yue Sie" uniqKey="Wong Y" first="Yue Sie" last="Wong">Yue Sie Wong</name></author><author><name sortKey="Ho, Khek Yu" sort="Ho, Khek Yu" uniqKey="Ho K" first="Khek Yu" last="Ho">Khek Yu Ho</name></author></analytic><series><title level="j">Emerging infectious diseases</title><idno type="eISSN">1080-6059</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cost-Benefit Analysis</term><term>Cross Infection (prevention & control)</term><term>Disease Outbreaks</term><term>Humans</term><term>Influenza A Virus, H1N1 Subtype</term><term>Influenza, Human (epidemiology)</term><term>Influenza, Human (prevention & control)</term><term>Markov Chains</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (prevention & control)</term><term>Singapore</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Analyse coût-bénéfice</term><term>Chaines de Markov</term><term>Flambées de maladies</term><term>Grippe humaine ()</term><term>Grippe humaine (épidémiologie)</term><term>Humains</term><term>Infection croisée ()</term><term>Singapour</term><term>Sous-type H1N1 du virus de la grippe A</term><term>Syndrome respiratoire aigu sévère ()</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Singapore</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Influenza, Human</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cross Infection</term><term>Influenza, Human</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Grippe humaine</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cost-Benefit Analysis</term><term>Disease Outbreaks</term><term>Humans</term><term>Influenza A Virus, H1N1 Subtype</term><term>Markov Chains</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse coût-bénéfice</term><term>Chaines de Markov</term><term>Flambées de maladies</term><term>Grippe humaine</term><term>Humains</term><term>Infection croisée</term><term>Singapour</term><term>Sous-type H1N1 du virus de la grippe A</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Singapour</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The outbreak of influenza A pandemic (H1N1) 2009 prompted many countries in Asia, previously strongly affected by severe acute respiratory syndrome (SARS), to respond with stringent measures, particularly in preventing outbreaks in hospitals. We studied actual direct costs and cost-effectiveness of different response measures from a hospital perspective in tertiary hospitals in Singapore by simulating outbreaks of SARS, pandemic (H1N1) 2009, and 1918 Spanish influenza. Protection measures targeting only infected patients yielded lowest incremental cost/death averted of 23,000 (US dollars) for pandemic (H1N1) 2009. Enforced protection in high-risk areas (Yellow Alert) and full protection throughout the hospital (Orange Alert) averted deaths but came at an incremental cost of up to $2.5 million/death averted. SARS and Spanish influenza favored more stringent measures. High case-fatality rates, virulence, and high proportion of atypical manifestations impacted cost-effectiveness the most. A calibrated approach in accordance with viral characteristics and community risks may help refine responses to future epidemics.</div></front></TEI></pubmed></double></record>Pour manipuler ce document sous Unix (Dilib)
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