Children's vaccines do not induce cross reactivity against SARS‐CoV
Identifieur interne : 001858 ( Ncbi/Merge ); précédent : 001857; suivant : 001859Children's vaccines do not induce cross reactivity against SARS‐CoV
Auteurs : Yang Yu ; Huali Jin ; Ze Chen ; Qingling L. Yu ; Yijie J. Ma ; Xiaolin L. Sun ; Bin WangSource :
- Journal of Clinical Pathology [ 0021-9746 ] ; 2007.
Descripteurs français
- KwdFr :
- Animaux, Anticorps antiviraux (sang), Enfant, Enfant d'âge préscolaire, Humains, Immunisation, Lymphocytes T (immunologie), Nourrisson, Réactions croisées (immunologie), Souris, Souris de lignée C57BL, Syndrome respiratoire aigu sévère (immunologie), Sérums immuns (immunologie), Test ELISA (), Vaccins (immunologie), Virus du SRAS (immunologie).
- MESH :
English descriptors
- KwdEn :
- Animals, Antibodies, Viral (blood), Child, Child, Preschool, Cross Reactions (immunology), Enzyme-Linked Immunosorbent Assay (methods), Humans, Immune Sera (immunology), Immunization, Infant, Mice, Mice, Inbred C57BL, SARS Virus (immunology), Severe Acute Respiratory Syndrome (immunology), T-Lymphocytes (immunology), Vaccines (immunology).
- MESH :
- chemical , blood : Antibodies, Viral.
- immunology : Cross Reactions, Immune Sera, SARS Virus, Severe Acute Respiratory Syndrome, T-Lymphocytes, Vaccines.
- methods : Enzyme-Linked Immunosorbent Assay.
- Animals, Child, Child, Preschool, Humans, Immunization, Infant, Mice, Mice, Inbred C57BL.
Abstract
In contrast with adults, children infected by severe acute respiratory syndrome‐corona virus (SARS‐CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS‐CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS‐CoV. The results showed no marked cross reactivity against SARS‐CoV, which implies that the reduced symptoms among children infected by SARS‐CoV may be caused by other factors.
Url:
DOI: 10.1136/jcp.2006.038893
PubMed: 17264247
PubMed Central: 1860633
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PMC:1860633Le document en format XML
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<front><div type="abstract" xml:lang="en">In contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.</div>
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