Public health implications of using various case definitions in The Netherlands during the worldwide SARS outbreak
Identifieur interne : 001773 ( Ncbi/Merge ); précédent : 001772; suivant : 001774Public health implications of using various case definitions in The Netherlands during the worldwide SARS outbreak
Auteurs : A. Timen ; G. J. J. Van Doornum ; M. Schutten ; M. A. E. Conyn-Van Spaendonck ; J. W. M. Van Der Meer ; A. D. M. E. Osterhaus ; J. E. Van SteenbergenSource :
- Clinical Microbiology and Infection [ 1198-743X ] ; 2006.
Descripteurs français
- KwdFr :
- Allocation des ressources, Anticorps antiviraux (sang), Contrôle des maladies contagieuses (), Femelle, Flambées de maladies, Humains, Lutte contre l'infection (), Mâle, Normes de référence, Organisation mondiale de la santé, Pays-Bas (épidémiologie), Santé publique (normes), Sensibilité et spécificité, Surveillance de la population, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (épidémiologie), Virus du SRAS (génétique), Virus du SRAS (immunologie), Virus du SRAS (isolement et purification), Études rétrospectives.
- MESH :
- diagnostic : Syndrome respiratoire aigu sévère.
- génétique : Virus du SRAS.
- immunologie : Virus du SRAS.
- isolement et purification : Virus du SRAS.
- normes : Santé publique.
- sang : Anticorps antiviraux.
- épidémiologie : Pays-Bas, Syndrome respiratoire aigu sévère.
- Allocation des ressources, Contrôle des maladies contagieuses, Femelle, Flambées de maladies, Humains, Lutte contre l'infection, Mâle, Normes de référence, Organisation mondiale de la santé, Sensibilité et spécificité, Surveillance de la population, Syndrome respiratoire aigu sévère, Études rétrospectives.
- Wicri :
- geographic : Pays-Bas.
English descriptors
- KwdEn :
- Antibodies, Viral (blood), Communicable Disease Control (methods), Disease Outbreaks, Female, Humans, Infection Control (methods), Male, Netherlands (epidemiology), Population Surveillance, Public Health (standards), Reference Standards, Resource Allocation, Retrospective Studies, SARS Virus (genetics), SARS Virus (immunology), SARS Virus (isolation & purification), Sensitivity and Specificity, Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (prevention & control), World Health Organization.
- MESH :
- chemical , blood : Antibodies, Viral.
- geographic , epidemiology : Netherlands.
- diagnosis : Severe Acute Respiratory Syndrome.
- epidemiology : Severe Acute Respiratory Syndrome.
- genetics : SARS Virus.
- immunology : SARS Virus.
- isolation & purification : SARS Virus.
- methods : Communicable Disease Control, Infection Control.
- prevention & control : Severe Acute Respiratory Syndrome.
- standards : Public Health.
- Disease Outbreaks, Female, Humans, Male, Population Surveillance, Reference Standards, Resource Allocation, Retrospective Studies, Sensitivity and Specificity, World Health Organization.
Abstract
This study analysed the consequences of deviation from the WHO case definition for the assessment of patients with suspected severe acute respiratory syndrome (SARS) in The Netherlands during 2003. Between 17 March and 7 July 2003, as a result of dilemmas in balancing sensitivity and specificity, five different case definitions were used. The patients referred for SARS assessment were analysed from a public health perspective. None of the patients referred had SARS, based on serological and virological criteria. Nevertheless, all 72 patients required thorough assessment and, depending on the results of the assessment, institution of appropriate prevention and control measures. Changing case definitions caused confusion in classifying cases. A centralised assessment of the reported cases by a team with clinical and public health expertise (epidemiological and geographical risk assessment) is a practical solution for addressing differences in applying case definitions. The burden of managing non‐cases is an important issue when allocating public health resources, and should be taken into account during the preparation phase, rather than during an outbreak. This applies not only to SARS, but also to other public health threats, such as pandemic influenza or a bioterrorist episode.
Url:
DOI: 10.1111/j.1469-0691.2006.01552.x
PubMed: 17121628
PubMed Central: 7129494
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xml:lang="fr"><term>Pays-Bas</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>This study analysed the consequences of deviation from the WHO case definition for the assessment of patients with suspected severe acute respiratory syndrome (SARS) in The Netherlands during 2003. Between 17 March and 7 July 2003, as a result of dilemmas in balancing sensitivity and specificity, five different case definitions were used. The patients referred for SARS assessment were analysed from a public health perspective. None of the patients referred had SARS, based on serological and virological criteria. Nevertheless, all 72 patients required thorough assessment and, depending on the results of the assessment, institution of appropriate prevention and control measures. Changing case definitions caused confusion in classifying cases. A centralised assessment of the reported cases by a team with clinical and public health expertise (epidemiological and geographical risk assessment) is a practical solution for addressing differences in applying case definitions. The burden of managing non‐cases is an important issue when allocating public health resources, and should be taken into account during the preparation phase, rather than during an outbreak. This applies not only to SARS, but also to other public health threats, such as pandemic influenza or a bioterrorist episode.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Teutch, Sm" uniqKey="Teutch S">SM Teutch</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Knipe, Dm" uniqKey="Knipe D">DM Knipe</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><double pmid="17121628"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Public health implications of using various case definitions in The Netherlands during the worldwide SARS outbreak</title><author><name sortKey="Timen, A" sort="Timen, A" uniqKey="Timen A" first="A." last="Timen">A. Timen</name><affiliation><nlm:aff id="a1"></nlm:aff></affiliation></author><author><name sortKey="Van Doornum, G J J" sort="Van Doornum, G J J" uniqKey="Van Doornum G" first="G. J. J." last="Van Doornum">G. J. J. Van Doornum</name><affiliation><nlm:aff id="a2"></nlm:aff></affiliation></author><author><name sortKey="Schutten, M" sort="Schutten, M" uniqKey="Schutten M" first="M." last="Schutten">M. Schutten</name><affiliation><nlm:aff id="a2"></nlm:aff></affiliation></author><author><name sortKey="Conyn An Spaendonck, M A E" sort="Conyn An Spaendonck, M A E" uniqKey="Conyn An Spaendonck M" first="M. A. E." last="Conyn-Van Spaendonck">M. A. E. Conyn-Van Spaendonck</name><affiliation><nlm:aff id="a1"></nlm:aff></affiliation></author><author><name sortKey="Van Der Meer, J W M" sort="Van Der Meer, J W M" uniqKey="Van Der Meer J" first="J. W. M." last="Van Der Meer">J. W. M. Van Der Meer</name><affiliation><nlm:aff id="a3"></nlm:aff></affiliation></author><author><name sortKey="Osterhaus, A D M E" sort="Osterhaus, A D M E" uniqKey="Osterhaus A" first="A. D. M. E." last="Osterhaus">A. D. M. E. Osterhaus</name><affiliation><nlm:aff id="a2"></nlm:aff></affiliation></author><author><name sortKey="Van Steenbergen, J E" sort="Van Steenbergen, J E" uniqKey="Van Steenbergen J" first="J. E." last="Van Steenbergen">J. E. Van Steenbergen</name><affiliation><nlm:aff id="a1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">17121628</idno><idno type="pmc">7129494</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7129494</idno><idno type="RBID">PMC:7129494</idno><idno type="doi">10.1111/j.1469-0691.2006.01552.x</idno><date when="2006">2006</date><idno type="wicri:Area/Pmc/Corpus">000F07</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000F07</idno><idno type="wicri:Area/Pmc/Curation">000F07</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000F07</idno><idno type="wicri:Area/Pmc/Checkpoint">001073</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001073</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Public health implications of using various case definitions in The Netherlands during the worldwide SARS outbreak</title><author><name sortKey="Timen, A" sort="Timen, A" uniqKey="Timen A" first="A." last="Timen">A. Timen</name><affiliation><nlm:aff id="a1"></nlm:aff></affiliation></author><author><name sortKey="Van Doornum, G J J" sort="Van Doornum, G J J" uniqKey="Van Doornum G" first="G. J. J." last="Van Doornum">G. J. J. Van Doornum</name><affiliation><nlm:aff id="a2"></nlm:aff></affiliation></author><author><name sortKey="Schutten, M" sort="Schutten, M" uniqKey="Schutten M" first="M." last="Schutten">M. Schutten</name><affiliation><nlm:aff id="a2"></nlm:aff></affiliation></author><author><name sortKey="Conyn An Spaendonck, M A E" sort="Conyn An Spaendonck, M A E" uniqKey="Conyn An Spaendonck M" first="M. A. E." last="Conyn-Van Spaendonck">M. A. E. Conyn-Van Spaendonck</name><affiliation><nlm:aff id="a1"></nlm:aff></affiliation></author><author><name sortKey="Van Der Meer, J W M" sort="Van Der Meer, J W M" uniqKey="Van Der Meer J" first="J. W. M." last="Van Der Meer">J. W. M. Van Der Meer</name><affiliation><nlm:aff id="a3"></nlm:aff></affiliation></author><author><name sortKey="Osterhaus, A D M E" sort="Osterhaus, A D M E" uniqKey="Osterhaus A" first="A. D. M. E." last="Osterhaus">A. D. M. E. Osterhaus</name><affiliation><nlm:aff id="a2"></nlm:aff></affiliation></author><author><name sortKey="Van Steenbergen, J E" sort="Van Steenbergen, J E" uniqKey="Van Steenbergen J" first="J. E." last="Van Steenbergen">J. E. Van Steenbergen</name><affiliation><nlm:aff id="a1"></nlm:aff></affiliation></author></analytic><series><title level="j">Clinical Microbiology and Infection</title><idno type="ISSN">1198-743X</idno><idno type="eISSN">1469-0691</idno><imprint><date when="2006">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>This study analysed the consequences of deviation from the WHO case definition for the assessment of patients with suspected severe acute respiratory syndrome (SARS) in The Netherlands during 2003. Between 17 March and 7 July 2003, as a result of dilemmas in balancing sensitivity and specificity, five different case definitions were used. The patients referred for SARS assessment were analysed from a public health perspective. None of the patients referred had SARS, based on serological and virological criteria. Nevertheless, all 72 patients required thorough assessment and, depending on the results of the assessment, institution of appropriate prevention and control measures. Changing case definitions caused confusion in classifying cases. A centralised assessment of the reported cases by a team with clinical and public health expertise (epidemiological and geographical risk assessment) is a practical solution for addressing differences in applying case definitions. The burden of managing non‐cases is an important issue when allocating public health resources, and should be taken into account during the preparation phase, rather than during an outbreak. This applies not only to SARS, but also to other public health threats, such as pandemic influenza or a bioterrorist episode.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Teutch, Sm" uniqKey="Teutch S">SM Teutch</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Knipe, Dm" uniqKey="Knipe D">DM Knipe</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI></pmc><pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Public health implications of using various case definitions in The Netherlands during the worldwide SARS outbreak.</title><author><name sortKey="Timen, A" sort="Timen, A" uniqKey="Timen A" first="A" last="Timen">A. Timen</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. Aura.Timen@rivm.nl</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven</wicri:regionArea><wicri:noRegion>Bilthoven</wicri:noRegion></affiliation></author><author><name sortKey="Van Doornum, G J J" sort="Van Doornum, G J J" uniqKey="Van Doornum G" first="G J J" last="Van Doornum">G J J. Van Doornum</name></author><author><name sortKey="Schutten, M" sort="Schutten, M" uniqKey="Schutten M" first="M" last="Schutten">M. Schutten</name></author><author><name sortKey="Conyn Van Spaendonck, M A E" sort="Conyn Van Spaendonck, M A E" uniqKey="Conyn Van Spaendonck M" first="M A E" last="Conyn-Van Spaendonck">M A E. Conyn-Van Spaendonck</name></author><author><name sortKey="Van Der Meer, J W M" sort="Van Der Meer, J W M" uniqKey="Van Der Meer J" first="J W M" last="Van Der Meer">J W M. Van Der Meer</name></author><author><name sortKey="Osterhaus, A D M E" sort="Osterhaus, A D M E" uniqKey="Osterhaus A" first="A D M E" last="Osterhaus">A D M E. Osterhaus</name></author><author><name sortKey="Van Steenbergen, J E" sort="Van Steenbergen, J E" uniqKey="Van Steenbergen J" first="J E" last="Van Steenbergen">J E Van Steenbergen</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006</date><idno type="RBID">pubmed:17121628</idno><idno type="pmid">17121628</idno><idno type="doi">10.1111/j.1469-0691.2006.01552.x</idno><idno type="wicri:Area/PubMed/Corpus">001F81</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001F81</idno><idno type="wicri:Area/PubMed/Curation">001F81</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001F81</idno><idno type="wicri:Area/PubMed/Checkpoint">002049</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002049</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Public health implications of using various case definitions in The Netherlands during the worldwide SARS outbreak.</title><author><name sortKey="Timen, A" sort="Timen, A" uniqKey="Timen A" first="A" last="Timen">A. Timen</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. Aura.Timen@rivm.nl</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven</wicri:regionArea><wicri:noRegion>Bilthoven</wicri:noRegion></affiliation></author><author><name sortKey="Van Doornum, G J J" sort="Van Doornum, G J J" uniqKey="Van Doornum G" first="G J J" last="Van Doornum">G J J. Van Doornum</name></author><author><name sortKey="Schutten, M" sort="Schutten, M" uniqKey="Schutten M" first="M" last="Schutten">M. Schutten</name></author><author><name sortKey="Conyn Van Spaendonck, M A E" sort="Conyn Van Spaendonck, M A E" uniqKey="Conyn Van Spaendonck M" first="M A E" last="Conyn-Van Spaendonck">M A E. Conyn-Van Spaendonck</name></author><author><name sortKey="Van Der Meer, J W M" sort="Van Der Meer, J W M" uniqKey="Van Der Meer J" first="J W M" last="Van Der Meer">J W M. Van Der Meer</name></author><author><name sortKey="Osterhaus, A D M E" sort="Osterhaus, A D M E" uniqKey="Osterhaus A" first="A D M E" last="Osterhaus">A D M E. Osterhaus</name></author><author><name sortKey="Van Steenbergen, J E" sort="Van Steenbergen, J E" uniqKey="Van Steenbergen J" first="J E" last="Van Steenbergen">J E Van Steenbergen</name></author></analytic><series><title level="j">Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases</title><idno type="ISSN">1198-743X</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibodies, Viral (blood)</term><term>Communicable Disease Control (methods)</term><term>Disease Outbreaks</term><term>Female</term><term>Humans</term><term>Infection Control (methods)</term><term>Male</term><term>Netherlands (epidemiology)</term><term>Population Surveillance</term><term>Public Health (standards)</term><term>Reference Standards</term><term>Resource Allocation</term><term>Retrospective Studies</term><term>SARS Virus (genetics)</term><term>SARS Virus (immunology)</term><term>SARS Virus (isolation & purification)</term><term>Sensitivity and Specificity</term><term>Severe Acute Respiratory Syndrome (diagnosis)</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (prevention & control)</term><term>World Health Organization</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Allocation des ressources</term><term>Anticorps antiviraux (sang)</term><term>Contrôle des maladies contagieuses ()</term><term>Femelle</term><term>Flambées de maladies</term><term>Humains</term><term>Lutte contre l'infection ()</term><term>Mâle</term><term>Normes de référence</term><term>Organisation mondiale de la santé</term><term>Pays-Bas (épidémiologie)</term><term>Santé publique (normes)</term><term>Sensibilité et spécificité</term><term>Surveillance de la population</term><term>Syndrome respiratoire aigu sévère ()</term><term>Syndrome respiratoire aigu sévère (diagnostic)</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term><term>Virus du SRAS (génétique)</term><term>Virus du SRAS (immunologie)</term><term>Virus du SRAS (isolement et purification)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Netherlands</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Communicable Disease Control</term><term>Infection Control</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Santé publique</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Public Health</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Pays-Bas</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Disease Outbreaks</term><term>Female</term><term>Humans</term><term>Male</term><term>Population Surveillance</term><term>Reference Standards</term><term>Resource Allocation</term><term>Retrospective Studies</term><term>Sensitivity and Specificity</term><term>World Health Organization</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Allocation des ressources</term><term>Contrôle des maladies contagieuses</term><term>Femelle</term><term>Flambées de maladies</term><term>Humains</term><term>Lutte contre l'infection</term><term>Mâle</term><term>Normes de référence</term><term>Organisation mondiale de la santé</term><term>Sensibilité et spécificité</term><term>Surveillance de la population</term><term>Syndrome respiratoire aigu sévère</term><term>Études rétrospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Pays-Bas</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study analysed the consequences of deviation from the WHO case definition for the assessment of patients with suspected severe acute respiratory syndrome (SARS) in The Netherlands during 2003. Between 17 March and 7 July 2003, as a result of dilemmas in balancing sensitivity and specificity, five different case definitions were used. The patients referred for SARS assessment were analysed from a public health perspective. None of the patients referred had SARS, based on serological and virological criteria. Nevertheless, all 72 patients required thorough assessment and, depending on the results of the assessment, institution of appropriate prevention and control measures. Changing case definitions caused confusion in classifying cases. A centralised assessment of the reported cases by a team with clinical and public health expertise (epidemiological and geographical risk assessment) is a practical solution for addressing differences in applying case definitions. The burden of managing non-cases is an important issue when allocating public health resources, and should be taken into account during the preparation phase, rather than during an outbreak. This applies not only to SARS, but also to other public health threats, such as pandemic influenza or a bioterrorist episode.</div></front></TEI></pubmed></double></record>Pour manipuler ce document sous Unix (Dilib)
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