Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome.
Identifieur interne : 000F86 ( Ncbi/Merge ); précédent : 000F85; suivant : 000F87Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome.
Auteurs : Frankie W T. Cheng [Hong Kong] ; Enders K O. Ng ; Albert Martin Li ; Ellis K L. Hon ; Rossa W K. Chiu ; Y M Dennis Lo ; Pak C. NgSource :
- The Pediatric infectious disease journal [ 0891-3668 ] ; 2005.
Descripteurs français
- KwdFr :
- ARN viral (sang), Charge virale, Cytokines (sang), Facteurs temps, Femelle, Humains, Nourrisson, Syndrome respiratoire aigu sévère (immunologie), Syndrome respiratoire aigu sévère (physiopathologie), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (génétique), Virus du SRAS (isolement et purification), Virus du SRAS (physiologie).
- MESH :
- génétique : Virus du SRAS.
- immunologie : Syndrome respiratoire aigu sévère.
- isolement et purification : Virus du SRAS.
- physiologie : Virus du SRAS.
- physiopathologie : Syndrome respiratoire aigu sévère.
- sang : ARN viral, Cytokines.
- virologie : Syndrome respiratoire aigu sévère.
- Charge virale, Facteurs temps, Femelle, Humains, Nourrisson.
English descriptors
- KwdEn :
- Cytokines (blood), Female, Humans, Infant, RNA, Viral (blood), SARS Virus (genetics), SARS Virus (isolation & purification), SARS Virus (physiology), Severe Acute Respiratory Syndrome (immunology), Severe Acute Respiratory Syndrome (physiopathology), Severe Acute Respiratory Syndrome (virology), Time Factors, Viral Load.
- MESH :
- chemical , blood : Cytokines, RNA, Viral.
- genetics : SARS Virus.
- immunology : Severe Acute Respiratory Syndrome.
- isolation & purification : SARS Virus.
- physiology : SARS Virus.
- physiopathology : Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Female, Humans, Infant, Time Factors, Viral Load.
Abstract
The clinical findings, plasma viral load, cytokines and chemokines of a 4-month-old infant with severe acute respiratory syndrome (SARS) were assessed at different phases of the disease. Ribavirin failed to inhibit SARS coronavirus (SARS-CoV) replication. One-step real time reverse transcription-polymerase chain reaction for plasma SARS-CoV RNA quantification was useful for early diagnosis and monitoring viremia.
DOI: 10.1097/01.inf.0000164703.61282.3b
PubMed: 15933575
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 002704
- to stream PubMed, to step Curation: 002704
- to stream PubMed, to step Checkpoint: 002789
Links to Exploration step
pubmed:15933575Le document en format XML
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<orgName type="university">Université chinoise de Hong Kong</orgName>
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<author><name sortKey="Li, Albert Martin" sort="Li, Albert Martin" uniqKey="Li A" first="Albert Martin" last="Li">Albert Martin Li</name>
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<author><name sortKey="Hon, Ellis K L" sort="Hon, Ellis K L" uniqKey="Hon E" first="Ellis K L" last="Hon">Ellis K L. Hon</name>
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<author><name sortKey="Chiu, Rossa W K" sort="Chiu, Rossa W K" uniqKey="Chiu R" first="Rossa W K" last="Chiu">Rossa W K. Chiu</name>
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<term>Infant</term>
<term>RNA, Viral (blood)</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (isolation & purification)</term>
<term>SARS Virus (physiology)</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
<term>Severe Acute Respiratory Syndrome (physiopathology)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
<term>Time Factors</term>
<term>Viral Load</term>
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<term>Charge virale</term>
<term>Cytokines (sang)</term>
<term>Facteurs temps</term>
<term>Femelle</term>
<term>Humains</term>
<term>Nourrisson</term>
<term>Syndrome respiratoire aigu sévère (immunologie)</term>
<term>Syndrome respiratoire aigu sévère (physiopathologie)</term>
<term>Syndrome respiratoire aigu sévère (virologie)</term>
<term>Virus du SRAS (génétique)</term>
<term>Virus du SRAS (isolement et purification)</term>
<term>Virus du SRAS (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Cytokines</term>
<term>RNA, Viral</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term>
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<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Virus du SRAS</term>
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</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
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<keywords scheme="MESH" xml:lang="en"><term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Time Factors</term>
<term>Viral Load</term>
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<term>Facteurs temps</term>
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<front><div type="abstract" xml:lang="en">The clinical findings, plasma viral load, cytokines and chemokines of a 4-month-old infant with severe acute respiratory syndrome (SARS) were assessed at different phases of the disease. Ribavirin failed to inhibit SARS coronavirus (SARS-CoV) replication. One-step real time reverse transcription-polymerase chain reaction for plasma SARS-CoV RNA quantification was useful for early diagnosis and monitoring viremia.</div>
</front>
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<Month>07</Month>
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<DateRevised><Year>2019</Year>
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<Title>The Pediatric infectious disease journal</Title>
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<ArticleTitle>Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome.</ArticleTitle>
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<Abstract><AbstractText>The clinical findings, plasma viral load, cytokines and chemokines of a 4-month-old infant with severe acute respiratory syndrome (SARS) were assessed at different phases of the disease. Ribavirin failed to inhibit SARS coronavirus (SARS-CoV) replication. One-step real time reverse transcription-polymerase chain reaction for plasma SARS-CoV RNA quantification was useful for early diagnosis and monitoring viremia.</AbstractText>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Cheng</LastName>
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<AffiliationInfo><Affiliation>Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N.T.</Affiliation>
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<affiliations><list><country><li>Hong Kong</li>
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<tree><noCountry><name sortKey="Chiu, Rossa W K" sort="Chiu, Rossa W K" uniqKey="Chiu R" first="Rossa W K" last="Chiu">Rossa W K. Chiu</name>
<name sortKey="Hon, Ellis K L" sort="Hon, Ellis K L" uniqKey="Hon E" first="Ellis K L" last="Hon">Ellis K L. Hon</name>
<name sortKey="Li, Albert Martin" sort="Li, Albert Martin" uniqKey="Li A" first="Albert Martin" last="Li">Albert Martin Li</name>
<name sortKey="Lo, Y M Dennis" sort="Lo, Y M Dennis" uniqKey="Lo Y" first="Y M Dennis" last="Lo">Y M Dennis Lo</name>
<name sortKey="Ng, Enders K O" sort="Ng, Enders K O" uniqKey="Ng E" first="Enders K O" last="Ng">Enders K O. Ng</name>
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<country name="Hong Kong"><noRegion><name sortKey="Cheng, Frankie W T" sort="Cheng, Frankie W T" uniqKey="Cheng F" first="Frankie W T" last="Cheng">Frankie W T. Cheng</name>
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