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Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis

Identifieur interne : 000E78 ( Ncbi/Merge ); précédent : 000E77; suivant : 000E79

Annulling a dangerous liaison: vaccination strategies against AIDS and tuberculosis

Auteurs : Stefan H E. Kaufmann [Allemagne] ; Andrew J. Mcmichael

Source :

RBID : PMC:7095892

Descripteurs français

English descriptors

Abstract

Human immunodeficiency virus (HIV) and Mycobacterium tuberculosis annually cause 3 million and 2 million deaths, respectively. Last year, 600,000 individuals, doubly infected with HIV and M. tuberculosis, died. Since World War I, approximately 150 million people have succumbed to these two infections—more total deaths than in all wars in the last 2,000 years. Although the perceived threats of new infections such as SARS, new variant Creutzfeldt-Jakob disease and anthrax are real, these outbreaks have caused less than 1,000 deaths globally, a death toll AIDS and tuberculosis exact every 2 h. In 2003, 40 million people were infected with HIV, 2 billion with M. tuberculosis, and 15 million with both. Last year, 5 million and 50 million were newly infected with HIV or M. tuberculosis, respectively, with 2 million new double infections. Better control measures are urgently needed.


Url:
DOI: 10.1038/nm1221
PubMed: 15812488
PubMed Central: 7095892

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PMC:7095892

Le document en format XML

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<p id="Par1">Human immunodeficiency virus (HIV) and
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<italic>M. tuberculosis</italic>
, died. Since World War I, approximately 150 million people have succumbed to these two infections—more total deaths than in all wars in the last 2,000 years. Although the perceived threats of new infections such as SARS, new variant Creutzfeldt-Jakob disease and anthrax are real, these outbreaks have caused less than 1,000 deaths globally, a death toll AIDS and tuberculosis exact every 2 h. In 2003, 40 million people were infected with HIV, 2 billion with
<italic>M. tuberculosis</italic>
, and 15 million with both. Last year, 5 million and 50 million were newly infected with HIV or
<italic>M. tuberculosis</italic>
, respectively, with 2 million new double infections. Better control measures are urgently needed.</p>
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<institution-id institution-id-type="ISNI">0000 0001 2306 7492</institution-id>
<institution>Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington,</institution>
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Oxford, OX3 9DS UK</nlm:aff>
<wicri:noCountry code="subfield">OX3 9DS UK</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Nature Medicine</title>
<idno type="ISSN">1078-8956</idno>
<idno type="eISSN">1546-170X</idno>
<imprint>
<date when="2005">2005</date>
</imprint>
</series>
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</fileDesc>
<profileDesc>
<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p id="Par1">Human immunodeficiency virus (HIV) and
<italic>Mycobacterium tuberculosis</italic>
annually cause 3 million and 2 million deaths, respectively. Last year, 600,000 individuals, doubly infected with HIV and
<italic>M. tuberculosis</italic>
, died. Since World War I, approximately 150 million people have succumbed to these two infections—more total deaths than in all wars in the last 2,000 years. Although the perceived threats of new infections such as SARS, new variant Creutzfeldt-Jakob disease and anthrax are real, these outbreaks have caused less than 1,000 deaths globally, a death toll AIDS and tuberculosis exact every 2 h. In 2003, 40 million people were infected with HIV, 2 billion with
<italic>M. tuberculosis</italic>
, and 15 million with both. Last year, 5 million and 50 million were newly infected with HIV or
<italic>M. tuberculosis</italic>
, respectively, with 2 million new double infections. Better control measures are urgently needed.</p>
</div>
</front>
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<term>Mycobacterium bovis (immunologie)</term>
<term>Mycobacterium tuberculosis (génétique)</term>
<term>Mycobacterium tuberculosis (immunologie)</term>
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<term>Humains</term>
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<div type="abstract" xml:lang="en">Human immunodeficiency virus (HIV) and Mycobacterium tuberculosis annually cause 3 million and 2 million deaths, respectively. Last year, 600,000 individuals, doubly infected with HIV and M. tuberculosis, died. Since World War I, approximately 150 million people have succumbed to these two infections--more total deaths than in all wars in the last 2,000 years. Although the perceived threats of new infections such as SARS, new variant Creutzfeldt-Jakob disease and anthrax are real, these outbreaks have caused less than 1,000 deaths globally, a death toll AIDS and tuberculosis exact every 2 h. In 2003, 40 million people were infected with HIV, 2 billion with M. tuberculosis, and 15 million with both. Last year, 5 million and 50 million were newly infected with HIV or M. tuberculosis, respectively, with 2 million new double infections. Better control measures are urgently needed.</div>
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