Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome.
Identifieur interne : 000561 ( Ncbi/Merge ); précédent : 000560; suivant : 000562Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome.
Auteurs : Y. Guan [République populaire de Chine] ; J S M. Peiris ; B. Zheng ; L L M. Poon ; K H Chan ; F Y Zeng ; C W M. Chan ; M N Chan ; J D Chen ; K Y C. Chow ; C C Hon ; K H Hui ; J. Li ; V Y Y. Li ; Y. Wang ; S W Leung ; K Y Yuen ; F C LeungSource :
- Lancet (London, England) [ 1474-547X ] ; 2004.
Descripteurs français
- KwdFr :
- ARN viral (génétique), Bases de données d'acides nucléiques (), Canada (épidémiologie), Flambées de maladies (), Génome viral, Hong Kong (épidémiologie), Humains, Singapour (épidémiologie), Syndrome respiratoire aigu sévère (transmission), Syndrome respiratoire aigu sévère (virologie), Syndrome respiratoire aigu sévère (épidémiologie), Techniques d'amplification d'acides nucléiques (), Vietnam (épidémiologie), Virus du SRAS (génétique), Épidémiologie moléculaire.
- MESH :
- génétique : ARN viral, Virus du SRAS.
- virologie : Syndrome respiratoire aigu sévère.
- épidémiologie : Canada, Hong Kong, Singapour, Syndrome respiratoire aigu sévère, Vietnam.
- Bases de données d'acides nucléiques, Flambées de maladies, Génome viral, Humains, Techniques d'amplification d'acides nucléiques, Épidémiologie moléculaire.
- Wicri :
English descriptors
- KwdEn :
- Canada (epidemiology), Databases, Nucleic Acid (statistics & numerical data), Disease Outbreaks (statistics & numerical data), Genome, Viral, Hong Kong (epidemiology), Humans, Molecular Epidemiology, Nucleic Acid Amplification Techniques (methods), RNA, Viral (genetics), SARS Virus (genetics), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (transmission), Severe Acute Respiratory Syndrome (virology), Singapore (epidemiology), Vietnam (epidemiology).
- MESH :
- chemical , genetics : RNA, Viral.
- geographic , epidemiology : Canada, Hong Kong, Singapore, Vietnam.
- epidemiology : Severe Acute Respiratory Syndrome.
- genetics : SARS Virus.
- methods : Nucleic Acid Amplification Techniques.
- statistics & numerical data : Databases, Nucleic Acid, Disease Outbreaks.
- transmission : Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Genome, Viral, Humans, Molecular Epidemiology.
Abstract
Severe acute respiratory syndrome (SARS) is a newly emerged disease caused by a novel coronavirus (SARS-CoV), which spread globally in early 2003, affecting over 30 countries. We have used molecular epidemiology to define the patterns of spread of the virus in Hong Kong and beyond.
DOI: 10.1016/s0140-6736(03)15259-2
PubMed: 14726162
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pubmed:14726162Le document en format XML
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Guan</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, University of Hong Kong, Hong Kong SAR, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, University of Hong Kong, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author><author><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J S M" last="Peiris">J S M. Peiris</name></author><author><name sortKey="Zheng, B" sort="Zheng, B" uniqKey="Zheng B" first="B" last="Zheng">B. Zheng</name></author><author><name sortKey="Poon, L L M" sort="Poon, L L M" uniqKey="Poon L" first="L L M" last="Poon">L L M. 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We have used molecular epidemiology to define the patterns of spread of the virus in Hong Kong and beyond.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">14726162</PMID><DateCompleted><Year>2004</Year><Month>02</Month><Day>27</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>07</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1474-547X</ISSN><JournalIssue CitedMedium="Internet"><Volume>363</Volume><Issue>9403</Issue><PubDate><Year>2004</Year><Month>Jan</Month><Day>10</Day></PubDate></JournalIssue><Title>Lancet (London, England)</Title><ISOAbbreviation>Lancet</ISOAbbreviation></Journal><ArticleTitle>Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome.</ArticleTitle><Pagination><MedlinePgn>99-104</MedlinePgn></Pagination><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Severe acute respiratory syndrome (SARS) is a newly emerged disease caused by a novel coronavirus (SARS-CoV), which spread globally in early 2003, affecting over 30 countries. We have used molecular epidemiology to define the patterns of spread of the virus in Hong Kong and beyond.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The case definition of SARS was based on that recommended by WHO. We genetically sequenced the gene for the S1 unit of the viral spike protein of viruses from patients with SARS in Hong Kong (138) and Guangdong (three) in February to April, 2003. We undertook phylogenetic comparisons with 27 other sequences available from public databases (Genbank).</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">Most of the Hong Kong viruses (139/142), including those from a large outbreak in an apartment block, clustered closely together with the isolate from a single index case (HKU-33) who came from Guangdong to Hong Kong in late February. Three other isolates were genetically distinct from HKU-33 in Hong Kong during February, but none of these contributed substantially to the subsequent local outbreak. Viruses identified in Guangdong and Beijing were genetically more diverse.</AbstractText><AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">The molecular epidemiological evidence suggests that most SARS-CoV from the outbreak in Hong Kong, as well as the viruses from Canada, Vietnam, and Singapore, are genetically closely linked. Three viruses found in Hong Kong in February were phylogenetically distinct from the major cluster, which suggests that several introductions of the virus had occurred, but that only one was associated with the subsequent outbreak in Hong Kong, which in turn spread globally.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Guan</LastName><ForeName>Y</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Department of Microbiology, University of Hong Kong, Hong Kong SAR, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peiris</LastName><ForeName>J S M</ForeName><Initials>JS</Initials></Author><Author ValidYN="Y"><LastName>Zheng</LastName><ForeName>B</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Poon</LastName><ForeName>L L M</ForeName><Initials>LL</Initials></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>K H</ForeName><Initials>KH</Initials></Author><Author ValidYN="Y"><LastName>Zeng</LastName><ForeName>F Y</ForeName><Initials>FY</Initials></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>C W M</ForeName><Initials>CW</Initials></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>M N</ForeName><Initials>MN</Initials></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>J D</ForeName><Initials>JD</Initials></Author><Author ValidYN="Y"><LastName>Chow</LastName><ForeName>K Y C</ForeName><Initials>KY</Initials></Author><Author ValidYN="Y"><LastName>Hon</LastName><ForeName>C C</ForeName><Initials>CC</Initials></Author><Author ValidYN="Y"><LastName>Hui</LastName><ForeName>K H</ForeName><Initials>KH</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>V Y Y</ForeName><Initials>VY</Initials></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Y</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Leung</LastName><ForeName>S W</ForeName><Initials>SW</Initials></Author><Author ValidYN="Y"><LastName>Yuen</LastName><ForeName>K Y</ForeName><Initials>KY</Initials></Author><Author ValidYN="Y"><LastName>Leung</LastName><ForeName>F C</ForeName><Initials>FC</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>A195357</GrantID><Agency>PHS HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Lancet</MedlineTA><NlmUniqueID>2985213R</NlmUniqueID><ISSNLinking>0140-6736</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012367">RNA, Viral</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N" Type="Geographic">Canada</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D030561" MajorTopicYN="N">Databases, Nucleic Acid</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016679" MajorTopicYN="N">Genome, Viral</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006723" MajorTopicYN="N" Type="Geographic">Hong Kong</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017720" MajorTopicYN="N">Molecular Epidemiology</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D021141" MajorTopicYN="N">Nucleic Acid Amplification Techniques</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012367" MajorTopicYN="N">RNA, Viral</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS 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Chan</name><name sortKey="Chan, K H" sort="Chan, K H" uniqKey="Chan K" first="K H" last="Chan">K H Chan</name><name sortKey="Chan, M N" sort="Chan, M N" uniqKey="Chan M" first="M N" last="Chan">M N Chan</name><name sortKey="Chen, J D" sort="Chen, J D" uniqKey="Chen J" first="J D" last="Chen">J D Chen</name><name sortKey="Chow, K Y C" sort="Chow, K Y C" uniqKey="Chow K" first="K Y C" last="Chow">K Y C. Chow</name><name sortKey="Hon, C C" sort="Hon, C C" uniqKey="Hon C" first="C C" last="Hon">C C Hon</name><name sortKey="Hui, K H" sort="Hui, K H" uniqKey="Hui K" first="K H" last="Hui">K H Hui</name><name sortKey="Leung, F C" sort="Leung, F C" uniqKey="Leung F" first="F C" last="Leung">F C Leung</name><name sortKey="Leung, S W" sort="Leung, S W" uniqKey="Leung S" first="S W" last="Leung">S W Leung</name><name sortKey="Li, J" sort="Li, J" uniqKey="Li J" first="J" last="Li">J. Li</name><name sortKey="Li, V Y Y" sort="Li, V Y Y" uniqKey="Li V" first="V Y Y" last="Li">V Y Y. Li</name><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J S M" last="Peiris">J S M. Peiris</name><name sortKey="Poon, L L M" sort="Poon, L L M" uniqKey="Poon L" first="L L M" last="Poon">L L M. Poon</name><name sortKey="Wang, Y" sort="Wang, Y" uniqKey="Wang Y" first="Y" last="Wang">Y. Wang</name><name sortKey="Yuen, K Y" sort="Yuen, K Y" uniqKey="Yuen K" first="K Y" last="Yuen">K Y Yuen</name><name sortKey="Zeng, F Y" sort="Zeng, F Y" uniqKey="Zeng F" first="F Y" last="Zeng">F Y Zeng</name><name sortKey="Zheng, B" sort="Zheng, B" uniqKey="Zheng B" first="B" last="Zheng">B. Zheng</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Guan, Y" sort="Guan, Y" uniqKey="Guan Y" first="Y" last="Guan">Y. Guan</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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