Mosaic evolution of the severe acute respiratory syndrome coronavirus.
Identifieur interne : 000501 ( Ncbi/Merge ); précédent : 000500; suivant : 000502Mosaic evolution of the severe acute respiratory syndrome coronavirus.
Auteurs : John Stavrinides [Canada] ; David S. GuttmanSource :
- Journal of virology [ 0022-538X ] ; 2004.
Descripteurs français
- KwdFr :
- Animaux, Biologie informatique (), Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (génétique), Humains, Phylogénie, Polyprotéines (génétique), Protéines de l'enveloppe virale (génétique), Protéines de la matrice virale (génétique), Protéines nucléocapside (génétique), Protéines virales (génétique), Recombinaison génétique, Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (génétique), Évolution biologique.
- MESH :
- génétique : Glycoprotéines membranaires, Polyprotéines, Protéines de l'enveloppe virale, Protéines de la matrice virale, Protéines nucléocapside, Protéines virales, Virus du SRAS.
- virologie : Syndrome respiratoire aigu sévère.
- Animaux, Biologie informatique, Glycoprotéine de spicule des coronavirus, Humains, Phylogénie, Recombinaison génétique, Évolution biologique.
English descriptors
- KwdEn :
- Animals, Biological Evolution, Computational Biology (methods), Humans, Membrane Glycoproteins (genetics), Nucleocapsid Proteins (genetics), Phylogeny, Polyproteins (genetics), Recombination, Genetic, SARS Virus (genetics), Severe Acute Respiratory Syndrome (virology), Spike Glycoprotein, Coronavirus, Viral Envelope Proteins (genetics), Viral Matrix Proteins (genetics), Viral Proteins (genetics).
- MESH :
- chemical , genetics : Membrane Glycoproteins, Nucleocapsid Proteins, Polyproteins, Viral Envelope Proteins, Viral Matrix Proteins, Viral Proteins.
- genetics : SARS Virus.
- methods : Computational Biology.
- virology : Severe Acute Respiratory Syndrome.
- Animals, Biological Evolution, Humans, Phylogeny, Recombination, Genetic, Spike Glycoprotein, Coronavirus.
Abstract
Severe acute respiratory syndrome (SARS) is a deadly form of pneumonia caused by a novel coronavirus, a viral family responsible for mild respiratory tract infections in a wide variety of animals including humans, pigs, cows, mice, cats, and birds. Analyses to date have been unable to identify the precise origin of the SARS coronavirus. We used Bayesian, neighbor-joining, and split decomposition phylogenetic techniques on the SARS virus replicase, surface spike, matrix, and nucleocapsid proteins to reveal the evolutionary origin of this recently emerging infectious agent. The analyses support a mammalian-like origin for the replicase protein, an avian-like origin for the matrix and nucleocapsid proteins, and a mammalian-avian mosaic origin for the host-determining spike protein. A bootscan recombination analysis of the spike gene revealed high nucleotide identity between the SARS virus and a feline infectious peritonitis virus throughout the gene, except for a 200- base-pair region of high identity to an avian sequence. These data support the phylogenetic analyses and suggest a possible past recombination event between mammalian-like and avian-like parent viruses. This event occurred near a region that has been implicated to be the human receptor binding site and may have been directly responsible for the switch of host of the SARS coronavirus from animals to humans.
DOI: 10.1128/jvi.78.1.76-82.2004
PubMed: 14671089
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 003048
- to stream PubMed, to step Curation: 003048
- to stream PubMed, to step Checkpoint: 002B85
Links to Exploration step
pubmed:14671089Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mosaic evolution of the severe acute respiratory syndrome coronavirus.</title><author><name sortKey="Stavrinides, John" sort="Stavrinides, John" uniqKey="Stavrinides J" first="John" last="Stavrinides">John Stavrinides</name><affiliation wicri:level="4"><nlm:affiliation>Department of Botany, University of Toronto, Toronto, Ontario M5S 3B2, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Botany, University of Toronto, Toronto, Ontario M5S 3B2</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Guttman, David S" sort="Guttman, David S" uniqKey="Guttman D" first="David S" last="Guttman">David S. Guttman</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2004">2004</date><idno type="RBID">pubmed:14671089</idno><idno type="pmid">14671089</idno><idno type="doi">10.1128/jvi.78.1.76-82.2004</idno><idno type="wicri:Area/PubMed/Corpus">003048</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003048</idno><idno type="wicri:Area/PubMed/Curation">003048</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003048</idno><idno type="wicri:Area/PubMed/Checkpoint">002B85</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002B85</idno><idno type="wicri:Area/Ncbi/Merge">000501</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Mosaic evolution of the severe acute respiratory syndrome coronavirus.</title><author><name sortKey="Stavrinides, John" sort="Stavrinides, John" uniqKey="Stavrinides J" first="John" last="Stavrinides">John Stavrinides</name><affiliation wicri:level="4"><nlm:affiliation>Department of Botany, University of Toronto, Toronto, Ontario M5S 3B2, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Botany, University of Toronto, Toronto, Ontario M5S 3B2</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Guttman, David S" sort="Guttman, David S" uniqKey="Guttman D" first="David S" last="Guttman">David S. Guttman</name></author></analytic><series><title level="j">Journal of virology</title><idno type="ISSN">0022-538X</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Biological Evolution</term><term>Computational Biology (methods)</term><term>Humans</term><term>Membrane Glycoproteins (genetics)</term><term>Nucleocapsid Proteins (genetics)</term><term>Phylogeny</term><term>Polyproteins (genetics)</term><term>Recombination, Genetic</term><term>SARS Virus (genetics)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Spike Glycoprotein, Coronavirus</term><term>Viral Envelope Proteins (genetics)</term><term>Viral Matrix Proteins (genetics)</term><term>Viral Proteins (genetics)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Biologie informatique ()</term><term>Glycoprotéine de spicule des coronavirus</term><term>Glycoprotéines membranaires (génétique)</term><term>Humains</term><term>Phylogénie</term><term>Polyprotéines (génétique)</term><term>Protéines de l'enveloppe virale (génétique)</term><term>Protéines de la matrice virale (génétique)</term><term>Protéines nucléocapside (génétique)</term><term>Protéines virales (génétique)</term><term>Recombinaison génétique</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Virus du SRAS (génétique)</term><term>Évolution biologique</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Membrane Glycoproteins</term><term>Nucleocapsid Proteins</term><term>Polyproteins</term><term>Viral Envelope Proteins</term><term>Viral Matrix Proteins</term><term>Viral Proteins</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Glycoprotéines membranaires</term><term>Polyprotéines</term><term>Protéines de l'enveloppe virale</term><term>Protéines de la matrice virale</term><term>Protéines nucléocapside</term><term>Protéines virales</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Computational Biology</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Biological Evolution</term><term>Humans</term><term>Phylogeny</term><term>Recombination, Genetic</term><term>Spike Glycoprotein, Coronavirus</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Biologie informatique</term><term>Glycoprotéine de spicule des coronavirus</term><term>Humains</term><term>Phylogénie</term><term>Recombinaison génétique</term><term>Évolution biologique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is a deadly form of pneumonia caused by a novel coronavirus, a viral family responsible for mild respiratory tract infections in a wide variety of animals including humans, pigs, cows, mice, cats, and birds. Analyses to date have been unable to identify the precise origin of the SARS coronavirus. We used Bayesian, neighbor-joining, and split decomposition phylogenetic techniques on the SARS virus replicase, surface spike, matrix, and nucleocapsid proteins to reveal the evolutionary origin of this recently emerging infectious agent. The analyses support a mammalian-like origin for the replicase protein, an avian-like origin for the matrix and nucleocapsid proteins, and a mammalian-avian mosaic origin for the host-determining spike protein. A bootscan recombination analysis of the spike gene revealed high nucleotide identity between the SARS virus and a feline infectious peritonitis virus throughout the gene, except for a 200- base-pair region of high identity to an avian sequence. These data support the phylogenetic analyses and suggest a possible past recombination event between mammalian-like and avian-like parent viruses. This event occurred near a region that has been implicated to be the human receptor binding site and may have been directly responsible for the switch of host of the SARS coronavirus from animals to humans.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">14671089</PMID><DateCompleted><Year>2004</Year><Month>01</Month><Day>20</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-538X</ISSN><JournalIssue CitedMedium="Print"><Volume>78</Volume><Issue>1</Issue><PubDate><Year>2004</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Journal of virology</Title><ISOAbbreviation>J. Virol.</ISOAbbreviation></Journal><ArticleTitle>Mosaic evolution of the severe acute respiratory syndrome coronavirus.</ArticleTitle><Pagination><MedlinePgn>76-82</MedlinePgn></Pagination><Abstract><AbstractText>Severe acute respiratory syndrome (SARS) is a deadly form of pneumonia caused by a novel coronavirus, a viral family responsible for mild respiratory tract infections in a wide variety of animals including humans, pigs, cows, mice, cats, and birds. Analyses to date have been unable to identify the precise origin of the SARS coronavirus. We used Bayesian, neighbor-joining, and split decomposition phylogenetic techniques on the SARS virus replicase, surface spike, matrix, and nucleocapsid proteins to reveal the evolutionary origin of this recently emerging infectious agent. The analyses support a mammalian-like origin for the replicase protein, an avian-like origin for the matrix and nucleocapsid proteins, and a mammalian-avian mosaic origin for the host-determining spike protein. A bootscan recombination analysis of the spike gene revealed high nucleotide identity between the SARS virus and a feline infectious peritonitis virus throughout the gene, except for a 200- base-pair region of high identity to an avian sequence. These data support the phylogenetic analyses and suggest a possible past recombination event between mammalian-like and avian-like parent viruses. This event occurred near a region that has been implicated to be the human receptor binding site and may have been directly responsible for the switch of host of the SARS coronavirus from animals to humans.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Stavrinides</LastName><ForeName>John</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Botany, University of Toronto, Toronto, Ontario M5S 3B2, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Guttman</LastName><ForeName>David S</ForeName><Initials>DS</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Virol</MedlineTA><NlmUniqueID>0113724</NlmUniqueID><ISSNLinking>0022-538X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008562">Membrane Glycoproteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D019590">Nucleocapsid Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D020815">Polyproteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D064370">Spike Glycoprotein, Coronavirus</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014759">Viral Envelope Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014763">Viral Matrix Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014764">Viral Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C099602">nucleocapsid protein, Coronavirus</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C578557">spike glycoprotein, SARS-CoV</NameOfSubstance></Chemical><Chemical><RegistryNumber>108502-71-2</RegistryNumber><NameOfSubstance UI="C067997">M protein, Coronavirus</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005075" MajorTopicYN="Y">Biological Evolution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019295" MajorTopicYN="N">Computational Biology</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008562" MajorTopicYN="N">Membrane Glycoproteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019590" MajorTopicYN="N">Nucleocapsid Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020815" MajorTopicYN="N">Polyproteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011995" MajorTopicYN="Y">Recombination, Genetic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D064370" MajorTopicYN="N">Spike Glycoprotein, Coronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014759" MajorTopicYN="N">Viral Envelope Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014763" MajorTopicYN="N">Viral Matrix Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014764" MajorTopicYN="N">Viral Proteins</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>12</Month><Day>13</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2004</Year><Month>1</Month><Day>21</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>12</Month><Day>13</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">14671089</ArticleId><ArticleId IdType="pmc">PMC303383</ArticleId><ArticleId IdType="doi">10.1128/jvi.78.1.76-82.2004</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Science. 2003 May 30;300(5624):1399-404</Citation><ArticleIdList><ArticleId IdType="pubmed">12730501</ArticleId></ArticleIdList></Reference><Reference><Citation>Acta Biochim Pol. 2001;48(2):391-407</Citation><ArticleIdList><ArticleId IdType="pubmed">11732610</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1999 Jan;73(1):152-60</Citation><ArticleIdList><ArticleId IdType="pubmed">9847317</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioinformatics. 2001 Dec;17(12):1244-5</Citation><ArticleIdList><ArticleId IdType="pubmed">11751241</ArticleId></ArticleIdList></Reference><Reference><Citation>Adv Exp Med Biol. 2001;494:173-81</Citation><ArticleIdList><ArticleId IdType="pubmed">11774465</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2002 Mar 1;294(1):222-36</Citation><ArticleIdList><ArticleId IdType="pubmed">11886280</ArticleId></ArticleIdList></Reference><Reference><Citation>Vaccine. 2002 May 15;20 Suppl 2:S16-20</Citation><ArticleIdList><ArticleId IdType="pubmed">12110250</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2002 Sep 15;301(1):109-20</Citation><ArticleIdList><ArticleId IdType="pubmed">12359451</ArticleId></ArticleIdList></Reference><Reference><Citation>Med Microbiol Immunol. 2002 Oct;191(2):63-74</Citation><ArticleIdList><ArticleId IdType="pubmed">12410344</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2002 Dec;76(24):12491-502</Citation><ArticleIdList><ArticleId IdType="pubmed">12438575</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Cells. 2002 Oct 31;14(2):295-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12442904</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2003 Jan;77(2):841-50</Citation><ArticleIdList><ArticleId IdType="pubmed">12502800</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2003 Feb;77(4):2530-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12551991</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2003 Apr;77(8):4528-38</Citation><ArticleIdList><ArticleId IdType="pubmed">12663759</ArticleId></ArticleIdList></Reference><Reference><Citation>Intervirology. 2003;46(2):71-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12684545</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2003 Apr 19;361(9366):1319-25</Citation><ArticleIdList><ArticleId IdType="pubmed">12711465</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1967-76</Citation><ArticleIdList><ArticleId IdType="pubmed">12690091</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1948-51</Citation><ArticleIdList><ArticleId IdType="pubmed">12748314</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 May 30;300(5624):1394-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12730500</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 May 30;300(5624):1351</Citation><ArticleIdList><ArticleId IdType="pubmed">12775803</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2003 May 24;361(9371):1779-85</Citation><ArticleIdList><ArticleId IdType="pubmed">12781537</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 Jun 13;300(5626):1763-7</Citation><ArticleIdList><ArticleId IdType="pubmed">12746549</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 Jun 20;300(5627):1961-6</Citation><ArticleIdList><ArticleId IdType="pubmed">12766206</ArticleId></ArticleIdList></Reference><Reference><Citation>Wkly Epidemiol Rec. 2003 Jun 6;78(23):197-200</Citation><ArticleIdList><ArticleId IdType="pubmed">12854302</ArticleId></ArticleIdList></Reference><Reference><Citation>Science. 2003 Oct 10;302(5643):276-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12958366</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1989 Nov;63(11):4603-8</Citation><ArticleIdList><ArticleId IdType="pubmed">2795713</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 1992 Jun 4;357(6377):420-2</Citation><ArticleIdList><ArticleId IdType="pubmed">1350662</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1994 Aug;68(8):4738-46</Citation><ArticleIdList><ArticleId IdType="pubmed">8035476</ArticleId></ArticleIdList></Reference><Reference><Citation>AIDS Res Hum Retroviruses. 1995 Nov;11(11):1423-5</Citation><ArticleIdList><ArticleId IdType="pubmed">8573403</ArticleId></ArticleIdList></Reference><Reference><Citation>Comput Appl Biosci. 1996 Aug;12(4):357-8</Citation><ArticleIdList><ArticleId IdType="pubmed">8902363</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 1997 Dec 15;25(24):4876-82</Citation><ArticleIdList><ArticleId IdType="pubmed">9396791</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioinformatics. 1998;14(1):68-73</Citation><ArticleIdList><ArticleId IdType="pubmed">9520503</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 1999 Sep;73(9):7607-18</Citation><ArticleIdList><ArticleId IdType="pubmed">10438851</ArticleId></ArticleIdList></Reference><Reference><Citation>Exp Clin Immunogenet. 1998;15(3):154-70</Citation><ArticleIdList><ArticleId IdType="pubmed">9813413</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioinformatics. 2001 Aug;17(8):754-5</Citation><ArticleIdList><ArticleId IdType="pubmed">11524383</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><noCountry><name sortKey="Guttman, David S" sort="Guttman, David S" uniqKey="Guttman D" first="David S" last="Guttman">David S. Guttman</name></noCountry><country name="Canada"><region name="Ontario"><name sortKey="Stavrinides, John" sort="Stavrinides, John" uniqKey="Stavrinides J" first="John" last="Stavrinides">John Stavrinides</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Ncbi/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000501 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd -nk 000501 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Ncbi
|étape= Merge
|type= RBID
|clé= pubmed:14671089
|texte= Mosaic evolution of the severe acute respiratory syndrome coronavirus.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Merge/RBID.i -Sk "pubmed:14671089" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Merge/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |