[Primary investigation on the changing mode of plasma specific IgG antibody in SARS patients and their physicians and nurses].
Identifieur interne : 000285 ( Ncbi/Merge ); précédent : 000284; suivant : 000286[Primary investigation on the changing mode of plasma specific IgG antibody in SARS patients and their physicians and nurses].
Auteurs : Guobin Xu [République populaire de Chine] ; Haiying Lu ; Jie Li ; Yonghua Li ; Zhenru Feng ; Na Hou ; Guangfa Wang ; Zhen-Dong Zhao ; Guohua Zhang ; Cunling Yan ; Haixia Li ; Xiaoming Gao ; Xiaoyuan Xu ; Guiqiang Wang ; Hui ZhuangSource :
- Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences [ 1671-167X ] ; 2003.
Descripteurs français
- KwdFr :
- MESH :
- immunologie : Syndrome respiratoire aigu sévère, Virus du SRAS.
- sang : Anticorps antiviraux, Immunoglobuline G.
- épidémiologie : Chine, Syndrome respiratoire aigu sévère.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, Sensibilité et spécificité, Test ELISA.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Adult, Antibodies, Viral (blood), China (epidemiology), Enzyme-Linked Immunosorbent Assay, Female, Humans, Immunoglobulin G (blood), Male, Middle Aged, SARS Virus (immunology), Sensitivity and Specificity, Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (immunology).
- MESH :
- chemical , blood : Antibodies, Viral, Immunoglobulin G.
- geographic , epidemiology : China.
- epidemiology : Severe Acute Respiratory Syndrome.
- immunology : SARS Virus, Severe Acute Respiratory Syndrome.
- Adult, Enzyme-Linked Immunosorbent Assay, Female, Humans, Male, Middle Aged, Sensitivity and Specificity.
Abstract
To primarily investigate the changing mode of anti-SARS coronavirus IgG antibody in clinically diagnosed SARS patients and the possibility of subclinical infection in physicians and nurses through close association with SARS patients.
PubMed: 12914210
Links toward previous steps (curation, corpus...)
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pubmed:12914210Le document en format XML
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Li</name></author><author><name sortKey="Feng, Zhenru" sort="Feng, Zhenru" uniqKey="Feng Z" first="Zhenru" last="Feng">Zhenru Feng</name></author><author><name sortKey="Hou, Na" sort="Hou, Na" uniqKey="Hou N" first="Na" last="Hou">Na Hou</name></author><author><name sortKey="Wang, Guangfa" sort="Wang, Guangfa" uniqKey="Wang G" first="Guangfa" last="Wang">Guangfa Wang</name></author><author><name sortKey="Zhao, Zhen Dong" sort="Zhao, Zhen Dong" uniqKey="Zhao Z" first="Zhen-Dong" last="Zhao">Zhen-Dong Zhao</name></author><author><name sortKey="Zhang, Guohua" sort="Zhang, Guohua" uniqKey="Zhang G" first="Guohua" last="Zhang">Guohua Zhang</name></author><author><name sortKey="Yan, Cunling" sort="Yan, Cunling" uniqKey="Yan C" first="Cunling" last="Yan">Cunling Yan</name></author><author><name sortKey="Li, Haixia" sort="Li, Haixia" uniqKey="Li H" first="Haixia" last="Li">Haixia Li</name></author><author><name sortKey="Gao, Xiaoming" sort="Gao, Xiaoming" uniqKey="Gao X" first="Xiaoming" last="Gao">Xiaoming Gao</name></author><author><name sortKey="Xu, Xiaoyuan" sort="Xu, Xiaoyuan" uniqKey="Xu X" first="Xiaoyuan" last="Xu">Xiaoyuan Xu</name></author><author><name sortKey="Wang, Guiqiang" sort="Wang, Guiqiang" uniqKey="Wang G" first="Guiqiang" last="Wang">Guiqiang Wang</name></author><author><name sortKey="Zhuang, Hui" sort="Zhuang, Hui" uniqKey="Zhuang H" first="Hui" last="Zhuang">Hui Zhuang</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2003">2003</date><idno type="RBID">pubmed:12914210</idno><idno type="pmid">12914210</idno><idno type="wicri:Area/PubMed/Corpus">003228</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003228</idno><idno type="wicri:Area/PubMed/Curation">003228</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003228</idno><idno type="wicri:Area/PubMed/Checkpoint">002F20</idno><idno type="wicri:explorRef" 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sortKey="Li, Yonghua" sort="Li, Yonghua" uniqKey="Li Y" first="Yonghua" last="Li">Yonghua Li</name></author><author><name sortKey="Feng, Zhenru" sort="Feng, Zhenru" uniqKey="Feng Z" first="Zhenru" last="Feng">Zhenru Feng</name></author><author><name sortKey="Hou, Na" sort="Hou, Na" uniqKey="Hou N" first="Na" last="Hou">Na Hou</name></author><author><name sortKey="Wang, Guangfa" sort="Wang, Guangfa" uniqKey="Wang G" first="Guangfa" last="Wang">Guangfa Wang</name></author><author><name sortKey="Zhao, Zhen Dong" sort="Zhao, Zhen Dong" uniqKey="Zhao Z" first="Zhen-Dong" last="Zhao">Zhen-Dong Zhao</name></author><author><name sortKey="Zhang, Guohua" sort="Zhang, Guohua" uniqKey="Zhang G" first="Guohua" last="Zhang">Guohua Zhang</name></author><author><name sortKey="Yan, Cunling" sort="Yan, Cunling" uniqKey="Yan C" first="Cunling" last="Yan">Cunling Yan</name></author><author><name sortKey="Li, Haixia" sort="Li, Haixia" uniqKey="Li H" first="Haixia" last="Li">Haixia Li</name></author><author><name sortKey="Gao, Xiaoming" sort="Gao, Xiaoming" uniqKey="Gao X" first="Xiaoming" last="Gao">Xiaoming Gao</name></author><author><name sortKey="Xu, Xiaoyuan" sort="Xu, Xiaoyuan" uniqKey="Xu X" first="Xiaoyuan" last="Xu">Xiaoyuan Xu</name></author><author><name sortKey="Wang, Guiqiang" sort="Wang, Guiqiang" uniqKey="Wang G" first="Guiqiang" last="Wang">Guiqiang Wang</name></author><author><name sortKey="Zhuang, Hui" sort="Zhuang, Hui" uniqKey="Zhuang H" first="Hui" last="Zhuang">Hui Zhuang</name></author></analytic><series><title level="j">Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences</title><idno type="ISSN">1671-167X</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Antibodies, Viral (blood)</term><term>China (epidemiology)</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Female</term><term>Humans</term><term>Immunoglobulin G (blood)</term><term>Male</term><term>Middle Aged</term><term>SARS Virus (immunology)</term><term>Sensitivity and Specificity</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Anticorps antiviraux (sang)</term><term>Chine (épidémiologie)</term><term>Femelle</term><term>Humains</term><term>Immunoglobuline G (sang)</term><term>Mâle</term><term>Sensibilité et spécificité</term><term>Syndrome respiratoire aigu sévère (immunologie)</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term><term>Test ELISA</term><term>Virus du SRAS (immunologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term><term>Immunoglobulin G</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>China</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>SARS Virus</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term><term>Immunoglobuline G</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Chine</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Sensitivity and Specificity</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Sensibilité et spécificité</term><term>Test ELISA</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To primarily investigate the changing mode of anti-SARS coronavirus IgG antibody in clinically diagnosed SARS patients and the possibility of subclinical infection in physicians and nurses through close association with SARS patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12914210</PMID><DateCompleted><Year>2003</Year><Month>08</Month><Day>26</Day></DateCompleted><DateRevised><Year>2017</Year><Month>11</Month><Day>16</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1671-167X</ISSN><JournalIssue CitedMedium="Print"><Volume>35 Suppl</Volume><PubDate><Year>2003</Year><Month>May</Month><Day>31</Day></PubDate></JournalIssue><Title>Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences</Title><ISOAbbreviation>Beijing Da Xue Xue Bao</ISOAbbreviation></Journal><ArticleTitle>[Primary investigation on the changing mode of plasma specific IgG antibody in SARS patients and their physicians and nurses].</ArticleTitle><Pagination><MedlinePgn>23-5</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To primarily investigate the changing mode of anti-SARS coronavirus IgG antibody in clinically diagnosed SARS patients and the possibility of subclinical infection in physicians and nurses through close association with SARS patients.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The plasma levels of anti-SARS coronavirus IgG antibody of 57 normal subjects, 127 physicians and nurses worked in SARS wards for one month and 73 SARS patients with different course of SARS were measured by enzyme linked immunosorbent assay.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Plasma anti-SARS coronavirus IgG antibody was not detected in normal subjects and the clinical personnel. After 0-7 days, 8-10 days, 11-14 days, 15-20 days of onset of disease, the positive rates were 0.33%, 52%, 86% respectively, and the general positive rate was 61%.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The specificity and sensitivity of ELISA to detect plasma anti-SARS IgG antibody were satisfactory. Cases with positive reaction could be diagnosed as patients already infected by the virus. The specific IgG antibody didn't emerge in some patients in the early stage of the disease, and the negative results didn't indicate that they were not infected. And follow-up investigation should be made in those patients. Unlike common epidemic infectious diseases, SARS probably hadn't the potentiality of subclinical infection.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Xu</LastName><ForeName>Guobin</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Peking University First Hospital, Beijing, 100034, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lu</LastName><ForeName>Haiying</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Jie</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Yonghua</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Feng</LastName><ForeName>Zhenru</ForeName><Initials>Z</Initials></Author><Author ValidYN="Y"><LastName>Hou</LastName><ForeName>Na</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Guangfa</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Zhen-dong</ForeName><Initials>ZD</Initials></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Guohua</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Yan</LastName><ForeName>Cunling</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Haixia</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Gao</LastName><ForeName>Xiaoming</ForeName><Initials>X</Initials></Author><Author ValidYN="Y"><LastName>Xu</LastName><ForeName>Xiaoyuan</ForeName><Initials>X</Initials></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Guiqiang</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Zhuang</LastName><ForeName>Hui</ForeName><Initials>H</Initials></Author></AuthorList><Language>chi</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>China</Country><MedlineTA>Beijing Da Xue Xue Bao Yi Xue Ban</MedlineTA><NlmUniqueID>101125284</NlmUniqueID><ISSNLinking>1671-167X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000914">Antibodies, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007074">Immunoglobulin G</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000914" MajorTopicYN="N">Antibodies, Viral</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002681" MajorTopicYN="N" Type="Geographic">China</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004797" MajorTopicYN="N">Enzyme-Linked Immunosorbent Assay</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007074" MajorTopicYN="N">Immunoglobulin G</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012680" MajorTopicYN="N">Sensitivity and Specificity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>8</Month><Day>14</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2003</Year><Month>8</Month><Day>27</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>8</Month><Day>14</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">12914210</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><noCountry><name sortKey="Feng, Zhenru" sort="Feng, Zhenru" uniqKey="Feng Z" first="Zhenru" last="Feng">Zhenru Feng</name><name sortKey="Gao, Xiaoming" sort="Gao, Xiaoming" uniqKey="Gao X" first="Xiaoming" last="Gao">Xiaoming Gao</name><name sortKey="Hou, Na" sort="Hou, Na" uniqKey="Hou N" first="Na" last="Hou">Na Hou</name><name sortKey="Li, Haixia" sort="Li, Haixia" uniqKey="Li H" first="Haixia" last="Li">Haixia Li</name><name sortKey="Li, Jie" sort="Li, Jie" uniqKey="Li J" first="Jie" last="Li">Jie Li</name><name sortKey="Li, Yonghua" sort="Li, Yonghua" uniqKey="Li Y" first="Yonghua" last="Li">Yonghua Li</name><name sortKey="Lu, Haiying" sort="Lu, Haiying" uniqKey="Lu H" first="Haiying" last="Lu">Haiying Lu</name><name sortKey="Wang, Guangfa" sort="Wang, Guangfa" uniqKey="Wang G" first="Guangfa" last="Wang">Guangfa Wang</name><name sortKey="Wang, Guiqiang" sort="Wang, Guiqiang" uniqKey="Wang G" first="Guiqiang" last="Wang">Guiqiang Wang</name><name sortKey="Xu, Xiaoyuan" sort="Xu, Xiaoyuan" uniqKey="Xu X" first="Xiaoyuan" last="Xu">Xiaoyuan Xu</name><name sortKey="Yan, Cunling" sort="Yan, Cunling" uniqKey="Yan C" first="Cunling" last="Yan">Cunling Yan</name><name sortKey="Zhang, Guohua" sort="Zhang, Guohua" uniqKey="Zhang G" first="Guohua" last="Zhang">Guohua Zhang</name><name sortKey="Zhao, Zhen Dong" sort="Zhao, Zhen Dong" uniqKey="Zhao Z" first="Zhen-Dong" last="Zhao">Zhen-Dong Zhao</name><name sortKey="Zhuang, Hui" sort="Zhuang, Hui" uniqKey="Zhuang H" first="Hui" last="Zhuang">Hui Zhuang</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Xu, Guobin" sort="Xu, Guobin" uniqKey="Xu G" first="Guobin" last="Xu">Guobin Xu</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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