| Ident. | Authors (with country if any) | Title |
|---|
| 000026 (2003) |
Angelo Ranise [Italie] ; Andrea Spallarossa ; Silvia Schenone ; Olga Bruno ; Francesco Bondavalli ; Laura Vargiu ; Tiziana Marceddu ; Massimo Mura ; Paolo La Colla ; Alessandra Pani | Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally related to phenethylthiazolylthiourea derivatives. |
| 000D46 (2005) |
Naoyuki Masuda [Japon] ; Osamu Yamamoto ; Masahiro Fujii ; Tetsuro Ohgami ; Jiro Fujiyasu ; Toru Kontani ; Ayako Moritomo ; Masaya Orita ; Hiroyuki Kurihara ; Hironobu Koga ; Shunji Kageyama ; Mitsuaki Ohta ; Hiroshi Inoue ; Toshifumi Hatta ; Masafumi Shintani ; Hiroshi Suzuki ; Kenji Sudo ; Yasuaki Shimizu ; Eiichi Kodama ; Masao Matsuoka ; Masatoshi Fujiwara ; Tomoyuki Yokota ; Shiro Shigeta ; Masanori Baba | Studies of non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: synthesis and structure-activity relationships of 2-cyano and 2-hydroxy thiazolidenebenzenesulfonamide derivatives. |
| 001256 (2005) |
Caterina Fattorusso [Italie] ; Sandra Gemma ; Stefania Butini ; Paul Huleatt ; Bruno Catalanotti ; Marco Persico ; Meri De Angelis ; Isabella Fiorini ; Vito Nacci ; Anna Ramunno ; Manuela Rodriquez ; Giovanni Greco ; Ettore Novellino ; Alberto Bergamini ; Stefano Marini ; Massimo Coletta ; Giovanni Maga ; Silvio Spadari ; Giuseppe Campiani | Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity. |
| 001B63 (2008) |
Sara Cesarini [Italie] ; Andrea Spallarossa ; Angelo Ranise ; Paola Fossa ; Paolo La Colla ; Giuseppina Sanna ; Gabriella Collu ; Roberta Loddo | Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure-activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamates. |
| 001B64 (2008) |
Sara Cesarini [Italie] ; Andrea Spallarossa ; Angelo Ranise ; Olga Bruno ; Paolo La Colla ; Barbara Secci ; Gabriella Collu ; Roberta Loddo | Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 2: Parallel synthesis, molecular modelling and structure-activity relationship studies on analogues of O-(2-phenylethyl)-N-phenylthiocarbamate. |
| 001D12 (2009) |
Yue-Ping Wang [République populaire de Chine] ; Fen-Er Chen ; Erik De Clercq ; Jan Balzarini ; Christophe Pannecouque | Synthesis and in vitro anti-HIV evaluation of a new series of 6-arylmethyl-substituted S-DABOs as potential non-nucleoside HIV-1 reverse transcriptase inhibitors. |
| 001D73 (2009) |
Andrea Spallarossa [Italie] ; Sara Cesarini ; Angelo Ranise ; Olga Bruno ; Silvia Schenone ; Paolo La Colla ; Gabriella Collu ; Giuseppina Sanna ; Barbara Secci ; Roberta Loddo | Novel modifications in the series of O-(2-phthalimidoethyl)-N-substituted thiocarbamates and their ring-opened congeners as non-nucleoside HIV-1 reverse transcriptase inhibitors. |
| 001E12 (2009) |
Andrea Spallarossa [Italie] ; Sara Cesarini ; Angelo Ranise ; Silvia Schenone ; Olga Bruno ; Alberto Borassi ; Paolo La Colla ; Margherita Pezzullo ; Giuseppina Sanna ; Gabriella Collu ; Barbara Secci ; Roberta Loddo | Parallel synthesis, molecular modelling and further structure-activity relationship studies of new acylthiocarbamates as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. |
| 002198 (2010) |
Zhu Xiaohe [République populaire de Chine] ; Qin Yu ; Yan Hong ; Song Xiuqing ; Zhong Rugang | Synthesis, biological evaluation and molecular modeling studies of N-aryl-2-arylthioacetamides as non-nucleoside HIV-1 reverse transcriptase inhibitors. |
| 002618 (2013) |
Dongyue Li [République populaire de Chine] ; Peng Zhan ; Huiqing Liu ; Christophe Pannecouque ; Jan Balzarini ; Erik De Clercq ; Xinyong Liu | Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs. |
| 002861 (2014) |
Diwakar Rai [République populaire de Chine] ; Wenmin Chen ; Peng Zhan ; Hong Liu ; Ye Tian ; Xin Liang ; Erik De Clercq ; Christophe Pannecouque ; Jan Balzarini ; Xinyong Liu | Synthesis and anti-HIV activity of 4-(naphthalen-1-yl)-1,2,5-thiadiazol-3-hydroxyl derivatives. |
| 002953 (2014) |
Xin Han [République populaire de Chine] ; Haoming Wu ; Wei Wang ; Chune Dong ; Po Tien ; Shuwen Wu ; Hai-Bing Zhou | Synthesis and SARs of indole-based α-amino acids as potent HIV-1 non-nucleoside reverse transcriptase inhibitors. |
| 002963 (2014) |
Zhaoqiang Liu [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Xinyong Liu [République populaire de Chine] | Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization. |
| 002A21 (2015) |
Boshi Huang [République populaire de Chine] ; Cuicui Li [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Tao Liu [République populaire de Chine] ; Mingyan Yu [République populaire de Chine] ; Lu Fu [République populaire de Chine] ; Yueyue Sun [République populaire de Chine] ; Huiqing Liu [République populaire de Chine] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Jan Balzarini [Belgique] ; Peng Zhan [République populaire de Chine] ; Xinyong Liu [République populaire de Chine] | Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches. |
| 002B10 (2015) |
Wenxin Li [République populaire de Chine] ; Xiao Li [République populaire de Chine] ; Erik De Clercq [Belgique] ; Peng Zhan [République populaire de Chine] ; Xinyong Liu [République populaire de Chine] | Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors from arylthioacetanilide structural motif. |
| 002B87 (2016) |
Jiapei Yang [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Dongwei Kang [République populaire de Chine] ; Xueyi Lu [République populaire de Chine] ; Xiao Li [République populaire de Chine] ; Zhaoqiang Liu [République populaire de Chine] ; Boshi Huang [République populaire de Chine] ; Dirk Daelemans [Belgique] ; Christophe Pannecouque [Belgique] ; Erik De Clercq [Belgique] ; Peng Zhan [République populaire de Chine] ; Xinyong Liu [République populaire de Chine] | Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket. |
| 002C26 (2016) |
Qing Meng [République populaire de Chine] ; Xuwang Chen [République populaire de Chine] ; Dongwei Kang [République populaire de Chine] ; Boshi Huang [République populaire de Chine] ; Wenxin Li [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Dirk Daelemans [Belgique] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Xinyong Liu [République populaire de Chine] | Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket. |
| 002E23 (2017) |
Boshi Huang [République populaire de Chine] ; Xueshun Wang [République populaire de Chine] ; Xinhao Liu [République populaire de Chine] ; Zihui Chen [République populaire de Chine] ; Wanzhuo Li [République populaire de Chine] ; Songkai Sun [République populaire de Chine] ; Huiqing Liu [République populaire de Chine] ; Dirk Daelemans [Belgique] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Peng Zhan [République populaire de Chine] ; Xinyong Liu [République populaire de Chine] | Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays. |
| 002F03 (2018) |
Zhongxia Zhou [République populaire de Chine] ; Tao Liu ; Dongwei Kang ; Zhipeng Huo ; Gaochan Wu ; Dirk Daelemans ; Erik De Clercq ; Christophe Pannecouque ; Peng Zhan ; Xinyong Liu | Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored "hydrophobic channel". |
| 002F20 (2018) |
Xueyi Lu [République populaire de Chine] ; Jiapei Yang [République populaire de Chine] ; Dongwei Kang [République populaire de Chine] ; Ping Gao [République populaire de Chine] ; Dirk Daelemans [Belgique] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Peng Zhan [République populaire de Chine] ; Xinyong Liu [République populaire de Chine] | The discovery of novel diarylpyri(mi)dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2. |
| 002F54 (2018) |
Rakhi Gawali [Inde] ; Jay Trivedi [Inde] ; Sujit Bhansali [Inde] ; Raghunath Bhosale [Inde] ; Dhiman Sarkar [Inde] ; Debashis Mitra [Inde] | Design, synthesis, docking studies and biological screening of 2-thiazolyl substituted -2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines as potent HIV-1 reverse transcriptase inhibitors. |
