| Ident. | Authors (with country if any) | Title |
|---|
| 001021 (2005) |
Jiun-Jie Shie [Taïwan] ; Jim-Min Fang ; Chih-Jung Kuo ; Tun-Hsun Kuo ; Po-Huang Liang ; Hung-Jyun Huang ; Wen-Bin Yang ; Chun-Hung Lin ; Jiun-Ling Chen ; Yin-Ta Wu ; Chi-Huey Wong | Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease. |
| 001027 (2005) |
Xiu-Xia Qu [République populaire de Chine] ; Pei Hao ; Xi-Jun Song ; Si-Ming Jiang ; Yan-Xia Liu ; Pei-Gang Wang ; Xi Rao ; Huai-Dong Song ; Sheng-Yue Wang ; Yu Zuo ; Ai-Hua Zheng ; Min Luo ; Hua-Lin Wang ; Fei Deng ; Han-Zhong Wang ; Zhi-Hong Hu ; Ming-Xiao Ding ; Guo-Ping Zhao ; Hong-Kui Deng | Identification of two critical amino acid residues of the severe acute respiratory syndrome coronavirus spike protein for its variation in zoonotic tropism transition via a double substitution strategy. |
| 001197 (2005) |
Linda A. Guarino [États-Unis] ; Kanchan Bhardwaj ; Wen Dong ; Jingchuan Sun ; Andreas Holzenburg ; Cheng Kao | Mutational analysis of the SARS virus Nsp15 endoribonuclease: identification of residues affecting hexamer formation. |
| 001210 (2005) |
Yujia Zhai [République populaire de Chine] ; Fei Sun [République populaire de Chine] ; Xuemei Li [République populaire de Chine] ; Hai Pang [République populaire de Chine] ; Xiaoling Xu [République populaire de Chine] ; Mark Bartlam [République populaire de Chine] ; Zihe Rao [République populaire de Chine] | Insights into SARS-CoV transcription and replication from the structure of the nsp7–nsp8 hexadecamer |
| 001229 (2005) |
Arun K. Ghosh [États-Unis] ; Kai Xi ; Kiira Ratia ; Bernard D. Santarsiero ; Wentao Fu ; Brian H. Harcourt ; Paul A. Rota ; Susan C. Baker ; Michael E. Johnson ; Andrew D. Mesecar | Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors. |
| 001230 (2005) |
Ulrich Kaeppler [Allemagne] ; Nikolaus Stiefl ; Markus Schiller ; Radim Vicik ; Alexander Breuning ; Werner Schmitz ; Daniel Rupprecht ; Carsten Schmuck ; Knut Baumann ; John Ziebuhr ; Tanja Schirmeister | A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods. |
| 001251 (2005) |
Kumar Singh Saikatendu ; Jeremiah S. Joseph ; Vanitha Subramanian ; Tom Clayton ; Mark Griffith ; Kin Moy ; Jeffrey Velasquez ; Benjamin W. Neuman ; Michael J. Buchmeier ; Raymond C. Stevens ; Peter Kuhn | Structural Basis of Severe Acute Respiratory Syndrome Coronavirus ADP-Ribose-1″-Phosphate Dephosphorylation by a Conserved Domain of nsP3 |
| 001256 (2005) |
Caterina Fattorusso [Italie] ; Sandra Gemma ; Stefania Butini ; Paul Huleatt ; Bruno Catalanotti ; Marco Persico ; Meri De Angelis ; Isabella Fiorini ; Vito Nacci ; Anna Ramunno ; Manuela Rodriquez ; Giovanni Greco ; Ettore Novellino ; Alberto Bergamini ; Stefano Marini ; Massimo Coletta ; Giovanni Maga ; Silvio Spadari ; Giuseppe Campiani | Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity. |
| 001294 (2006) |
Andrea J. Dooley [États-Unis] ; Nice Shindo ; Barbara Taggart ; Jewn-Giew Park ; Yuan-Ping Pang | From genome to drug lead: identification of a small-molecule inhibitor of the SARS virus. |
| 001326 (2005) |
Jan Balzarini ; Els Keyaerts ; Leen Vijgen ; Frank Vandermeer ; Miguel Stevens ; Erik De Clercq ; Herman Egberink ; Marc Van Ranst | Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture |
| 001330 (2006) |
Pi-Hui Liang [Taïwan] ; Wei-Chieh Cheng ; Yi-Ling Lee ; Han-Pang Yu ; Ying-Ta Wu ; Yi-Ling Lin ; Chi-Huey Wong | Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis. |
| 001361 (2006) |
Jong Hyun Cho [États-Unis] ; Dale L. Bernard ; Robert W. Sidwell ; Earl R. Kern ; Chung K. Chu | Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS. |
| 001419 (2006) |
Roberto Di Santo [Italie] ; Roberta Costi ; Alessandra Roux ; Marino Artico ; Antonio Lavecchia ; Luciana Marinelli ; Ettore Novellino ; Lucia Palmisano ; Mauro Andreotti ; Roberta Amici ; Clementina Maria Galluzzo ; Lucia Nencioni ; Anna Teresa Palamara ; Yves Pommier ; Christophe Marchand | Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action. |
| 001507 (2006) |
D-Q Wei [République populaire de Chine] ; R. Zhang ; Q-S Du ; W-N Gao ; Y. Li ; H. Gao ; S-Q Wang ; X. Zhang ; A-X Li ; S. Sirois ; K-C Chou | Anti-SARS drug screening by molecular docking. |
| 001520 (2006) |
Xingnan Li [États-Unis] ; Robert Vince | Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors. |
| 001526 (2006) |
Rakesh Kumar [Canada] ; Wassila Semaine ; Monika Johar ; D Lorne J. Tyrrell ; Babita Agrawal | Effect of various pyrimidines possessing the 1-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl] moiety, able to mimic natural 2'-deoxyribose, on wild-type and mutant hepatitis B virus replication. |
| 001563 (2006) |
Hui Li [États-Unis] ; John Tatlock ; Angelica Linton ; Javier Gonzalez ; Allen Borchardt ; Peter Dragovich ; Tanya Jewell ; Tom Prins ; Ru Zhou ; Julie Blazel ; Hans Parge ; Robert Love ; Michael Hickey ; Chau Doan ; Stephanie Shi ; Rohit Duggal ; Cristina Lewis ; Shella Fuhrman | Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors. |
| 001593 (2006) |
Yue-Qing Li [République populaire de Chine] ; Ze-Lin Li ; Wei-Jie Zhao ; Rui-Xing Wen ; Qing-Wei Meng ; Yi Zeng | Synthesis of stilbene derivatives with inhibition of SARS coronavirus replication. |
| 001599 (2006) |
Syaulan Yang [République populaire de Chine] ; Shu-Jen Chen ; Min-Feng Hsu ; Jen-Dar Wu ; Chien-Te K. Tseng ; Yu-Fan Liu ; Hua-Chien Chen ; Chun-Wei Kuo ; Chi-Shen Wu ; Li-Wen Chang ; Wen-Chang Chen ; Shao-Ying Liao ; Teng-Yuan Chang ; Hsin-Hui Hung ; Hui-Lin Shr ; Cheng-Yuan Liu ; Yu-An Huang ; Ling-Yin Chang ; Jen-Chi Hsu ; Clarence J. Peters ; Andrew H-J Wang ; Ming-Chu Hsu | Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor. |
| 001614 (2006) |
Pamela Hamill [Canada] ; Derek Hudson ; Richard Y. Kao ; Polly Chow ; Meera Raj ; Hongyan Xu ; Martin J. Richer ; François Jean | Development of a red-shifted fluorescence-based assay for SARS-coronavirus 3CL protease: identification of a novel class of anti-SARS agents from the tropical marine sponge Axinella corrugata. |
| 001621 (2006) |
Marie-Pierre Egloff [France] ; Hélène Malet ; Akos Putics ; Maarit Heinonen ; Hélène Dutartre ; Antoine Frangeul ; Arnaud Gruez ; Valérie Campanacci ; Christian Cambillau ; John Ziebuhr ; Tero Ahola ; Bruno Canard | Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains. |
