Antivirals for Respiratory Viral Infections: Problems and Prospects.
Identifieur interne : 002C90 ( Ncbi/Curation ); précédent : 002C89; suivant : 002C91Antivirals for Respiratory Viral Infections: Problems and Prospects.
Auteurs : Qiang Liu [République populaire de Chine] ; Yuan-Hong Zhou [République populaire de Chine] ; Feng Ye [République populaire de Chine] ; Zhan-Qiu Yang [République populaire de Chine]Source :
- Seminars in respiratory and critical care medicine [ 1098-9048 ] ; 2016.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (usage thérapeutique), Coronavirus du syndrome respiratoire du Moyen-Orient, Humains, Infections de l'appareil respiratoire (traitement médicamenteux), Infections de l'appareil respiratoire (virologie), Infections à coronavirus (traitement médicamenteux), Infections à coronavirus (virologie), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS.
- MESH :
- traitement médicamenteux : Infections de l'appareil respiratoire, Infections à coronavirus, Syndrome respiratoire aigu sévère.
- usage thérapeutique : Antiviraux.
- virologie : Infections de l'appareil respiratoire, Infections à coronavirus, Syndrome respiratoire aigu sévère.
- Animaux, Coronavirus du syndrome respiratoire du Moyen-Orient, Humains, Virus du SRAS.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (therapeutic use), Coronavirus Infections (drug therapy), Coronavirus Infections (virology), Humans, Middle East Respiratory Syndrome Coronavirus, Respiratory Tract Infections (drug therapy), Respiratory Tract Infections (virology), SARS Virus, Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (virology).
- MESH :
- chemical , therapeutic use : Antiviral Agents.
- drug therapy : Coronavirus Infections, Respiratory Tract Infections, Severe Acute Respiratory Syndrome.
- virology : Coronavirus Infections, Respiratory Tract Infections, Severe Acute Respiratory Syndrome.
- Animals, Humans, Middle East Respiratory Syndrome Coronavirus, SARS Virus.
Abstract
In the past two decades, several newly emerging and reemerging viral respiratory pathogens including several influenza viruses (avian influenza and pandemic influenza), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV), have continued to challenge medical and public health systems. Thereafter, the development of cost-effective, broad-spectrum antiviral agents is the urgent mission of both virologists and pharmacologists. Current antiviral developments have focused targets on viral entry, replication, release, and intercellular pathways essential for viral life cycle. Here, we review the current literature on challenges and prospects in the development of these antivirals.
DOI: 10.1055/s-0036-1584803
PubMed: 27486742
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pubmed:27486742Le document en format XML
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<term>Coronavirus Infections (virology)</term>
<term>Humans</term>
<term>Middle East Respiratory Syndrome Coronavirus</term>
<term>Respiratory Tract Infections (drug therapy)</term>
<term>Respiratory Tract Infections (virology)</term>
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<term>Infections de l'appareil respiratoire (traitement médicamenteux)</term>
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<term>Infections à coronavirus (traitement médicamenteux)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Syndrome respiratoire aigu sévère (traitement médicamenteux)</term>
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<front><div type="abstract" xml:lang="en">In the past two decades, several newly emerging and reemerging viral respiratory pathogens including several influenza viruses (avian influenza and pandemic influenza), severe acute respiratory syndrome coronavirus (SARS-CoV), and Middle East respiratory syndrome coronavirus (MERS-CoV), have continued to challenge medical and public health systems. Thereafter, the development of cost-effective, broad-spectrum antiviral agents is the urgent mission of both virologists and pharmacologists. Current antiviral developments have focused targets on viral entry, replication, release, and intercellular pathways essential for viral life cycle. Here, we review the current literature on challenges and prospects in the development of these antivirals.</div>
</front>
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