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Chlamydial Zoonoses

Identifieur interne : 002104 ( Ncbi/Curation ); précédent : 002103; suivant : 002105

Chlamydial Zoonoses

Auteurs : Gernot Rohde ; Eberhard Straube ; Andreas Essig ; Petra Reinhold ; Konrad Sachse

Source :

RBID : PMC:2847324

Abstract

Background

Zoonoses were already a subject of intense interest even before the SARS and avian influenza epidemics arose. For many years, chlamydiae have been hypothesized to be important zoonotic pathogens, because of their wide distribution and their infectious cycle. This article provides an overview of the current state of knowledge on this subject.

Methods

The authors present a selective review of the literature as well as their own findings.

Results

The scientific knowledge of the distribution and infectious cycle of chlamydiae is still inadequate. The laboratory diagnosis of chlamydial zoonoses remains unsatisfactory in both human and veterinary medicine, as there are no commercially available sensitive and species-specific tests. Acute chlamydial infections are usually treated with macrolides, tetracyclines, or quinolones. Persistent varieties are not covered by standard therapy.

Conclusions

There is a considerable need for research on chlamydial infections, especially with regard to the diagnosis and treatment of persistent varieties.


Url:
DOI: 10.3238/arztebl.2010.0174
PubMed: 20358033
PubMed Central: 2847324

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Gernot Rohde
<affiliation>
<nlm:aff id="AFF1">Medizinische Klinik III – Pneumologie, Allergologie und Schlaf- und Beatmungsmedizin, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH, Ruhr-Universität Bochum</nlm:aff>
<wicri:noCountry code="subfield">Ruhr-Universität Bochum</wicri:noCountry>
</affiliation>
Eberhard Straube
<affiliation>
<nlm:aff id="AFF2">Institut für Medizinische Mikrobiologie, Friedrich-Schiller-Universität Jena</nlm:aff>
<wicri:noCountry code="subfield">Friedrich-Schiller-Universität Jena</wicri:noCountry>
</affiliation>
Andreas Essig
<affiliation>
<nlm:aff id="AFF3">Institut für Medizinische Mikrobiologie und Hygiene, Universitätsklinik Ulm</nlm:aff>
<wicri:noCountry code="subfield">Universitätsklinik Ulm</wicri:noCountry>
</affiliation>
Petra Reinhold
<affiliation>
<nlm:aff id="AFF4">Institut für Molekulare Pathogenese am Friedrich-Loeffler-Institut, Standort Jena</nlm:aff>
<wicri:noCountry code="subfield">Standort Jena</wicri:noCountry>
</affiliation>
Konrad Sachse
<affiliation>
<nlm:aff id="AFF4">Institut für Molekulare Pathogenese am Friedrich-Loeffler-Institut, Standort Jena</nlm:aff>
<wicri:noCountry code="subfield">Standort Jena</wicri:noCountry>
</affiliation>

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<title>Background</title>
<p>Zoonoses were already a subject of intense interest even before the SARS and avian influenza epidemics arose. For many years, chlamydiae have been hypothesized to be important zoonotic pathogens, because of their wide distribution and their infectious cycle. This article provides an overview of the current state of knowledge on this subject.</p>
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<title>Methods</title>
<p>The authors present a selective review of the literature as well as their own findings.</p>
</sec>
<sec id="st3">
<title>Results</title>
<p>The scientific knowledge of the distribution and infectious cycle of chlamydiae is still inadequate. The laboratory diagnosis of chlamydial zoonoses remains unsatisfactory in both human and veterinary medicine, as there are no commercially available sensitive and species-specific tests. Acute chlamydial infections are usually treated with macrolides, tetracyclines, or quinolones. Persistent varieties are not covered by standard therapy.</p>
</sec>
<sec id="st4">
<title>Conclusions</title>
<p>There is a considerable need for research on chlamydial infections, especially with regard to the diagnosis and treatment of persistent varieties.</p>
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