Chlamydial Zoonoses
Identifieur interne : 002104 ( Ncbi/Curation ); précédent : 002103; suivant : 002105Chlamydial Zoonoses
Auteurs : Gernot Rohde ; Eberhard Straube ; Andreas Essig ; Petra Reinhold ; Konrad SachseSource :
- Deutsches Arzteblatt International [ 1866-0452 ] ; 2010.
Abstract
Zoonoses were already a subject of intense interest even before the SARS and avian influenza epidemics arose. For many years, chlamydiae have been hypothesized to be important zoonotic pathogens, because of their wide distribution and their infectious cycle. This article provides an overview of the current state of knowledge on this subject.
The authors present a selective review of the literature as well as their own findings.
The scientific knowledge of the distribution and infectious cycle of chlamydiae is still inadequate. The laboratory diagnosis of chlamydial zoonoses remains unsatisfactory in both human and veterinary medicine, as there are no commercially available sensitive and species-specific tests. Acute chlamydial infections are usually treated with macrolides, tetracyclines, or quinolones. Persistent varieties are not covered by standard therapy.
There is a considerable need for research on chlamydial infections, especially with regard to the diagnosis and treatment of persistent varieties.
Url:
DOI: 10.3238/arztebl.2010.0174
PubMed: 20358033
PubMed Central: 2847324
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Gernot Rohde<affiliation><nlm:aff id="AFF1">Medizinische Klinik III – Pneumologie, Allergologie und Schlaf- und Beatmungsmedizin, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil GmbH, Ruhr-Universität Bochum</nlm:aff>
<wicri:noCountry code="subfield">Ruhr-Universität Bochum</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="AFF2">Institut für Medizinische Mikrobiologie, Friedrich-Schiller-Universität Jena</nlm:aff>
<wicri:noCountry code="subfield">Friedrich-Schiller-Universität Jena</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="AFF3">Institut für Medizinische Mikrobiologie und Hygiene, Universitätsklinik Ulm</nlm:aff>
<wicri:noCountry code="subfield">Universitätsklinik Ulm</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="AFF4">Institut für Molekulare Pathogenese am Friedrich-Loeffler-Institut, Standort Jena</nlm:aff>
<wicri:noCountry code="subfield">Standort Jena</wicri:noCountry>
</affiliation>
<affiliation><nlm:aff id="AFF4">Institut für Molekulare Pathogenese am Friedrich-Loeffler-Institut, Standort Jena</nlm:aff>
<wicri:noCountry code="subfield">Standort Jena</wicri:noCountry>
</affiliation>
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<wicri:noCountry code="subfield">Friedrich-Schiller-Universität Jena</wicri:noCountry>
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<wicri:noCountry code="subfield">Universitätsklinik Ulm</wicri:noCountry>
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<wicri:noCountry code="subfield">Standort Jena</wicri:noCountry>
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<front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background</title>
<p>Zoonoses were already a subject of intense interest even before the SARS and avian influenza epidemics arose. For many years, chlamydiae have been hypothesized to be important zoonotic pathogens, because of their wide distribution and their infectious cycle. This article provides an overview of the current state of knowledge on this subject.</p>
</sec>
<sec id="st2"><title>Methods</title>
<p>The authors present a selective review of the literature as well as their own findings.</p>
</sec>
<sec id="st3"><title>Results</title>
<p>The scientific knowledge of the distribution and infectious cycle of chlamydiae is still inadequate. The laboratory diagnosis of chlamydial zoonoses remains unsatisfactory in both human and veterinary medicine, as there are no commercially available sensitive and species-specific tests. Acute chlamydial infections are usually treated with macrolides, tetracyclines, or quinolones. Persistent varieties are not covered by standard therapy.</p>
</sec>
<sec id="st4"><title>Conclusions</title>
<p>There is a considerable need for research on chlamydial infections, especially with regard to the diagnosis and treatment of persistent varieties.</p>
</sec>
</div>
</front>
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