The cytotoxicity to leukemia cells and antiviral effects of Isatis indigotica extracts on pseudorabies virus.
Identifieur interne : 001F12 ( Ncbi/Curation ); précédent : 001F11; suivant : 001F13The cytotoxicity to leukemia cells and antiviral effects of Isatis indigotica extracts on pseudorabies virus.
Auteurs : Shih-Ling Hsuan [République populaire de Chine] ; Shih-Chieh Chang ; Sheng-Yang Wang ; Tien-Ling Liao ; Ting-Ting Jong ; Maw-Sheng Chien ; Wei-Cheng Lee ; Shih-Shiung Chen ; Jiunn-Wang LiaoSource :
- Journal of ethnopharmacology [ 1872-7573 ] ; 2009.
Descripteurs français
- KwdFr :
- Animaux, Cellules HL-60, Effet cytopathogène viral, Extraits de plantes (pharmacologie), Herpèsvirus porcin de type 1 (), Herpèsvirus porcin de type 1 (pathogénicité), Herpèsvirus porcin de type 1 (physiologie), Humains, Isatis (), Leucémies (anatomopathologie), Réplication virale, Suidae, Tests de criblage d'agents antitumoraux.
- MESH :
- anatomopathologie : Leucémies.
- pathogénicité : Herpèsvirus porcin de type 1.
- pharmacologie : Extraits de plantes.
- physiologie : Herpèsvirus porcin de type 1.
- Animaux, Cellules HL-60, Effet cytopathogène viral, Herpèsvirus porcin de type 1, Humains, Isatis, Réplication virale, Suidae, Tests de criblage d'agents antitumoraux.
English descriptors
- KwdEn :
- MESH :
- chemical , pharmacology : Plant Extracts.
- chemistry : Isatis.
- drug effects : Herpesvirus 1, Suid.
- pathogenicity : Herpesvirus 1, Suid.
- pathology : Leukemia.
- physiology : Herpesvirus 1, Suid.
- Animals, Cytopathogenic Effect, Viral, Drug Screening Assays, Antitumor, HL-60 Cells, Humans, Swine, Virus Replication.
Abstract
Isatis indigotica (I. indigotica), Cruciferae, has been used in Chinese medicine for anti-leukemia and anti-severe acute respiratory syndrome (SARS). The aim of this study was to evaluate the cytotoxicity of Isatis indigotica extracts on human leukemia cell line (HL-60) and the antiviral activity on swine pseudorabies virus (PrV) in in vitro assays.
DOI: 10.1016/j.jep.2009.02.028
PubMed: 19429341
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pubmed:19429341Le document en format XML
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<term>HL-60 Cells</term>
<term>Herpesvirus 1, Suid (drug effects)</term>
<term>Herpesvirus 1, Suid (pathogenicity)</term>
<term>Herpesvirus 1, Suid (physiology)</term>
<term>Humans</term>
<term>Isatis (chemistry)</term>
<term>Leukemia (pathology)</term>
<term>Plant Extracts (pharmacology)</term>
<term>Swine</term>
<term>Virus Replication</term>
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<term>Effet cytopathogène viral</term>
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<term>Herpèsvirus porcin de type 1 ()</term>
<term>Herpèsvirus porcin de type 1 (pathogénicité)</term>
<term>Herpèsvirus porcin de type 1 (physiologie)</term>
<term>Humains</term>
<term>Isatis ()</term>
<term>Leucémies (anatomopathologie)</term>
<term>Réplication virale</term>
<term>Suidae</term>
<term>Tests de criblage d'agents antitumoraux</term>
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<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Isatis</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Leukemia</term>
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<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Extraits de plantes</term>
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<term>HL-60 Cells</term>
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<term>Virus Replication</term>
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<front><div type="abstract" xml:lang="en">Isatis indigotica (I. indigotica), Cruciferae, has been used in Chinese medicine for anti-leukemia and anti-severe acute respiratory syndrome (SARS). The aim of this study was to evaluate the cytotoxicity of Isatis indigotica extracts on human leukemia cell line (HL-60) and the antiviral activity on swine pseudorabies virus (PrV) in in vitro assays.</div>
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