Indomethacin has a potent antiviral activity against SARS coronavirus.
Identifieur interne : 001873 ( Ncbi/Curation ); précédent : 001872; suivant : 001874Indomethacin has a potent antiviral activity against SARS coronavirus.
Auteurs : Carla Amici [Italie] ; Antonino Di Caro ; Alessandra Ciucci ; Lucia Chiappa ; Concetta Castilletti ; Vito Martella ; Nicola Decaro ; Canio Buonavoglia ; Maria R. Capobianchi ; M Gabriella SantoroSource :
- Antiviral therapy [ 1359-6535 ] ; 2006.
Descripteurs français
- KwdFr :
- ARN viral (isolement et purification), Acide acétylsalicylique (pharmacologie), Animaux, Antiviraux (pharmacologie), Antiviraux (usage thérapeutique), Chiens, Coronavirus canin (), Fèces (virologie), Humains, Indométacine (pharmacologie), Indométacine (usage thérapeutique), Infections à coronavirus (médecine vétérinaire), Infections à coronavirus (traitement médicamenteux), Interféron alpha (pharmacologie), Lignée cellulaire, Maladies des chiens (traitement médicamenteux), Relation dose-effet des médicaments, Ribavirine (pharmacologie), Réplication virale (), Virus du SRAS ().
- MESH :
- isolement et purification : ARN viral.
- médecine vétérinaire : Infections à coronavirus.
- pharmacologie : Acide acétylsalicylique, Antiviraux, Indométacine, Interféron alpha, Ribavirine.
- traitement médicamenteux : Infections à coronavirus, Maladies des chiens.
- usage thérapeutique : Antiviraux, Indométacine.
- virologie : Fèces.
- Animaux, Chiens, Coronavirus canin, Humains, Lignée cellulaire, Relation dose-effet des médicaments, Réplication virale, Virus du SRAS.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (pharmacology), Antiviral Agents (therapeutic use), Aspirin (pharmacology), Cell Line, Chlorocebus aethiops, Coronavirus Infections (drug therapy), Coronavirus Infections (veterinary), Coronavirus, Canine (drug effects), Dog Diseases (drug therapy), Dogs, Dose-Response Relationship, Drug, Feces (virology), Humans, Indomethacin (pharmacology), Indomethacin (therapeutic use), Interferon-alpha (pharmacology), RNA, Viral (isolation & purification), Ribavirin (pharmacology), SARS Virus (drug effects), Virus Replication (drug effects).
- MESH :
- chemical , isolation & purification : RNA, Viral.
- chemical , pharmacology : Antiviral Agents, Aspirin, Indomethacin, Interferon-alpha, Ribavirin.
- chemical , therapeutic use : Antiviral Agents, Indomethacin.
- drug effects : Coronavirus, Canine, SARS Virus, Virus Replication.
- drug therapy : Coronavirus Infections, Dog Diseases.
- veterinary : Coronavirus Infections.
- virology : Feces.
- Animals, Cell Line, Chlorocebus aethiops, Dogs, Dose-Response Relationship, Drug, Humans.
Abstract
Severe acute respiratory syndrome (SARS) is a newly emerging, highly transmissible and fatal disease caused by a previously unknown coronavirus (SARS-CoV). Existing in non-identified animal reservoirs, SARS-CoV continues to represent a threat to humans because there is no effective specific antiviral therapy for coronavirus infections.
PubMed: 17302372
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001E95
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :001E95
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002144
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :001873
Links to Exploration step
pubmed:17302372Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Indomethacin has a potent antiviral activity against SARS coronavirus.</title><author><name sortKey="Amici, Carla" sort="Amici, Carla" uniqKey="Amici C" first="Carla" last="Amici">Carla Amici</name><affiliation wicri:level="3"><nlm:affiliation>Department of Biology, University of Rome Tor Vergata, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Biology, University of Rome Tor Vergata, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Di Caro, Antonino" sort="Di Caro, Antonino" uniqKey="Di Caro A" first="Antonino" last="Di Caro">Antonino Di Caro</name></author><author><name sortKey="Ciucci, Alessandra" sort="Ciucci, Alessandra" uniqKey="Ciucci A" first="Alessandra" last="Ciucci">Alessandra Ciucci</name></author><author><name sortKey="Chiappa, Lucia" sort="Chiappa, Lucia" uniqKey="Chiappa L" first="Lucia" last="Chiappa">Lucia Chiappa</name></author><author><name sortKey="Castilletti, Concetta" sort="Castilletti, Concetta" uniqKey="Castilletti C" first="Concetta" last="Castilletti">Concetta Castilletti</name></author><author><name sortKey="Martella, Vito" sort="Martella, Vito" uniqKey="Martella V" first="Vito" last="Martella">Vito Martella</name></author><author><name sortKey="Decaro, Nicola" sort="Decaro, Nicola" uniqKey="Decaro N" first="Nicola" last="Decaro">Nicola Decaro</name></author><author><name sortKey="Buonavoglia, Canio" sort="Buonavoglia, Canio" uniqKey="Buonavoglia C" first="Canio" last="Buonavoglia">Canio Buonavoglia</name></author><author><name sortKey="Capobianchi, Maria R" sort="Capobianchi, Maria R" uniqKey="Capobianchi M" first="Maria R" last="Capobianchi">Maria R. Capobianchi</name></author><author><name sortKey="Santoro, M Gabriella" sort="Santoro, M Gabriella" uniqKey="Santoro M" first="M Gabriella" last="Santoro">M Gabriella Santoro</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2006">2006</date><idno type="RBID">pubmed:17302372</idno><idno type="pmid">17302372</idno><idno type="wicri:Area/PubMed/Corpus">001E95</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001E95</idno><idno type="wicri:Area/PubMed/Curation">001E95</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001E95</idno><idno type="wicri:Area/PubMed/Checkpoint">002144</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002144</idno><idno type="wicri:Area/Ncbi/Merge">001873</idno><idno type="wicri:Area/Ncbi/Curation">001873</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Indomethacin has a potent antiviral activity against SARS coronavirus.</title><author><name sortKey="Amici, Carla" sort="Amici, Carla" uniqKey="Amici C" first="Carla" last="Amici">Carla Amici</name><affiliation wicri:level="3"><nlm:affiliation>Department of Biology, University of Rome Tor Vergata, Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Biology, University of Rome Tor Vergata, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Di Caro, Antonino" sort="Di Caro, Antonino" uniqKey="Di Caro A" first="Antonino" last="Di Caro">Antonino Di Caro</name></author><author><name sortKey="Ciucci, Alessandra" sort="Ciucci, Alessandra" uniqKey="Ciucci A" first="Alessandra" last="Ciucci">Alessandra Ciucci</name></author><author><name sortKey="Chiappa, Lucia" sort="Chiappa, Lucia" uniqKey="Chiappa L" first="Lucia" last="Chiappa">Lucia Chiappa</name></author><author><name sortKey="Castilletti, Concetta" sort="Castilletti, Concetta" uniqKey="Castilletti C" first="Concetta" last="Castilletti">Concetta Castilletti</name></author><author><name sortKey="Martella, Vito" sort="Martella, Vito" uniqKey="Martella V" first="Vito" last="Martella">Vito Martella</name></author><author><name sortKey="Decaro, Nicola" sort="Decaro, Nicola" uniqKey="Decaro N" first="Nicola" last="Decaro">Nicola Decaro</name></author><author><name sortKey="Buonavoglia, Canio" sort="Buonavoglia, Canio" uniqKey="Buonavoglia C" first="Canio" last="Buonavoglia">Canio Buonavoglia</name></author><author><name sortKey="Capobianchi, Maria R" sort="Capobianchi, Maria R" uniqKey="Capobianchi M" first="Maria R" last="Capobianchi">Maria R. Capobianchi</name></author><author><name sortKey="Santoro, M Gabriella" sort="Santoro, M Gabriella" uniqKey="Santoro M" first="M Gabriella" last="Santoro">M Gabriella Santoro</name></author></analytic><series><title level="j">Antiviral therapy</title><idno type="ISSN">1359-6535</idno><imprint><date when="2006" type="published">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antiviral Agents (pharmacology)</term><term>Antiviral Agents (therapeutic use)</term><term>Aspirin (pharmacology)</term><term>Cell Line</term><term>Chlorocebus aethiops</term><term>Coronavirus Infections (drug therapy)</term><term>Coronavirus Infections (veterinary)</term><term>Coronavirus, Canine (drug effects)</term><term>Dog Diseases (drug therapy)</term><term>Dogs</term><term>Dose-Response Relationship, Drug</term><term>Feces (virology)</term><term>Humans</term><term>Indomethacin (pharmacology)</term><term>Indomethacin (therapeutic use)</term><term>Interferon-alpha (pharmacology)</term><term>RNA, Viral (isolation & purification)</term><term>Ribavirin (pharmacology)</term><term>SARS Virus (drug effects)</term><term>Virus Replication (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (isolement et purification)</term><term>Acide acétylsalicylique (pharmacologie)</term><term>Animaux</term><term>Antiviraux (pharmacologie)</term><term>Antiviraux (usage thérapeutique)</term><term>Chiens</term><term>Coronavirus canin ()</term><term>Fèces (virologie)</term><term>Humains</term><term>Indométacine (pharmacologie)</term><term>Indométacine (usage thérapeutique)</term><term>Infections à coronavirus (médecine vétérinaire)</term><term>Infections à coronavirus (traitement médicamenteux)</term><term>Interféron alpha (pharmacologie)</term><term>Lignée cellulaire</term><term>Maladies des chiens (traitement médicamenteux)</term><term>Relation dose-effet des médicaments</term><term>Ribavirine (pharmacologie)</term><term>Réplication virale ()</term><term>Virus du SRAS ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antiviral Agents</term><term>Aspirin</term><term>Indomethacin</term><term>Interferon-alpha</term><term>Ribavirin</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Indomethacin</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Coronavirus, Canine</term><term>SARS Virus</term><term>Virus Replication</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Dog Diseases</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>ARN viral</term></keywords><keywords scheme="MESH" qualifier="médecine vétérinaire" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Acide acétylsalicylique</term><term>Antiviraux</term><term>Indométacine</term><term>Interféron alpha</term><term>Ribavirine</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term><term>Maladies des chiens</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term><term>Indométacine</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Fèces</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Feces</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Line</term><term>Chlorocebus aethiops</term><term>Dogs</term><term>Dose-Response Relationship, Drug</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Chiens</term><term>Coronavirus canin</term><term>Humains</term><term>Lignée cellulaire</term><term>Relation dose-effet des médicaments</term><term>Réplication virale</term><term>Virus du SRAS</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is a newly emerging, highly transmissible and fatal disease caused by a previously unknown coronavirus (SARS-CoV). Existing in non-identified animal reservoirs, SARS-CoV continues to represent a threat to humans because there is no effective specific antiviral therapy for coronavirus infections.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001873 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 001873 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= pubmed:17302372
|texte= Indomethacin has a potent antiviral activity against SARS coronavirus.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:17302372" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |