Inhibition of SARS-CoV gene expression by adenovirus-delivered small hairpin RNA.
Identifieur interne : 001782 ( Ncbi/Curation ); précédent : 001781; suivant : 001783Inhibition of SARS-CoV gene expression by adenovirus-delivered small hairpin RNA.
Auteurs : Xue Zhang [République populaire de Chine] ; Kailang Wu ; Xin Yue ; Ying Zhu ; Jianguo WuSource :
- Intervirology [ 0300-5526 ] ; 2007.
Descripteurs français
- KwdFr :
- ARN antisens (génétique), ARN viral (analyse), Adenoviridae (génétique), Animaux, Expression des gènes, Gènes rapporteurs, Humains, Lignée cellulaire, Luciferases (analyse), Protéines de l'enveloppe virale (biosynthèse), Protéines de l'enveloppe virale (génétique), Protéines nucléocapside (biosynthèse), Protéines nucléocapside (génétique), Protéines virales (analyse), RT-PCR, Réplication virale, Technique de Western, Vecteurs génétiques, Virus du SRAS (génétique), Virus du SRAS (physiologie).
- MESH :
- analyse : ARN viral, Luciferases, Protéines virales.
- biosynthèse : Protéines de l'enveloppe virale, Protéines nucléocapside.
- génétique : ARN antisens, Adenoviridae, Protéines de l'enveloppe virale, Protéines nucléocapside, Virus du SRAS.
- physiologie : Virus du SRAS.
- Animaux, Expression des gènes, Gènes rapporteurs, Humains, Lignée cellulaire, RT-PCR, Réplication virale, Technique de Western, Vecteurs génétiques.
English descriptors
- KwdEn :
- Adenoviridae (genetics), Animals, Blotting, Western, Cell Line, Chlorocebus aethiops, Gene Expression, Genes, Reporter, Genetic Vectors, Humans, Luciferases (analysis), Nucleocapsid Proteins (biosynthesis), Nucleocapsid Proteins (genetics), RNA, Antisense (genetics), RNA, Viral (analysis), Reverse Transcriptase Polymerase Chain Reaction, SARS Virus (genetics), SARS Virus (physiology), Viral Envelope Proteins (biosynthesis), Viral Envelope Proteins (genetics), Viral Proteins (analysis), Virus Replication.
- MESH :
- chemical , analysis : Luciferases, RNA, Viral, Viral Proteins.
- chemical , biosynthesis : Nucleocapsid Proteins, Viral Envelope Proteins.
- genetics : Adenoviridae, Nucleocapsid Proteins, RNA, Antisense, SARS Virus, Viral Envelope Proteins.
- physiology : SARS Virus.
- Animals, Blotting, Western, Cell Line, Chlorocebus aethiops, Gene Expression, Genes, Reporter, Genetic Vectors, Humans, Reverse Transcriptase Polymerase Chain Reaction, Virus Replication.
Abstract
Severe acute respiratory syndrome (SARS) is a highly contagious and lethal disease caused by a new type of coronavirus, SARS-associated coronavirus (SARS-CoV). Currently, there is no efficient treatment and prevention for this disease. We constructed recombinant adenoviral vectors that can express shRNAs, which inhibited the expression of SARS-CoV genes effectively in mammalian cells.
DOI: 10.1159/000097391
PubMed: 17139181
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pubmed:17139181Le document en format XML
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Currently, there is no efficient treatment and prevention for this disease. We constructed recombinant adenoviral vectors that can express shRNAs, which inhibited the expression of SARS-CoV genes effectively in mammalian cells.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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