| Ident. | Authors (with country if any) | Title |
|---|
| 001A60 (2007) |
Arun K. Ghosh [États-Unis] ; Kai Xi [États-Unis] ; Valerie Grum-Tokars [États-Unis] ; Xiaoming Xu [États-Unis] ; Kiira Ratia [États-Unis] ; Wentao Fu [États-Unis] ; Katherine V. Houser [États-Unis] ; Susan C. Baker [États-Unis] ; Michael E. Johnson [États-Unis] ; Andrew D. Mesecar [États-Unis] | Structure-based design, synthesis, and biological evaluation of peptidomimetic SARS-CoV 3CLpro inhibitors |
| 001D35 (2008) |
Yuli Xie [États-Unis] ; Anthony Raffo [États-Unis] ; Masanori Ichise [États-Unis] ; Shixian Deng [États-Unis] ; Paul E. Harris [États-Unis] ; Donald W. Landry [États-Unis] | Novel Hypoglycemic Dihydropyridones Serendipitously Discovered from O-versus C-Alkylation in The Synthesis of VMAT2 Antagonists |
| 001D48 (2008) |
Arun K. Ghosh [États-Unis] ; Gangli Gong [États-Unis] ; Valerie Grum-Tokars [États-Unis] ; Debbie C. Mulhearn [États-Unis] ; Susan C. Baker [États-Unis] ; Melissa Coughlin [États-Unis] ; Bellur S. Prabhakar [États-Unis] ; Katrina Sleeman [États-Unis] ; Michael E. Johnson [États-Unis] ; Andrew D. Mesecar [États-Unis] | Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors |
| 001E54 (2009) |
Chaewoon Lee [Corée du Sud] ; Jin Moo Lee ; Na-Ra Lee ; Bong-Suk Jin ; Kyoung Jin Jang ; Dong-Eun Kim ; Yong-Joo Jeong ; Youhoon Chong | Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase. |
| 001E87 (2009) |
Thomas Regnier [Japon] ; Diganta Sarma ; Koushi Hidaka ; Usman Bacha ; Ernesto Freire ; Yoshio Hayashi ; Yoshiaki Kiso | New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors. |
| 001F37 (2009) |
Christopher Mcguigan [Royaume-Uni] ; Mary Rose Kelleher ; Plinio Perrone ; Sinead Mulready ; Giovanna Luoni ; Felice Daverio ; Sonal Rajyaguru ; Sophie Le Pogam ; Isabel Najera ; Joseph A. Martin ; Klaus Klumpp ; David B. Smith | The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4'-azidocytidine (R1479). |
| 001F66 (2009) |
Chaewoon Lee [Corée du Sud] ; Jin Moo Lee ; Na-Ra Lee ; Dong-Eun Kim ; Yong-Joo Jeong ; Youhoon Chong | Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives. |
| 002006 (2009) |
Iou-Jiun Kang [République populaire de Chine] ; Li-Wen Wang ; Sheng-Ju Hsu ; Chung-Chi Lee ; Yen-Chun Lee ; Yen-Shian Wu ; Andrew Yueh ; Jing-Chyi Wang ; Tsu-An Hsu ; Yu-Sheng Chao ; Jyh-Haur Chern | Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors. |
| 002082 (2010) |
Young Bae Ryu [Corée du Sud] ; Su-Jin Park ; Young Min Kim ; Ju-Yeon Lee ; Woo Duck Seo ; Jong Sun Chang ; Ki Hun Park ; Mun-Chual Rho ; Woo Song Lee | SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii. |
| 002142 (2010) |
Xianfeng Li [États-Unis] ; Yong-Kang Zhang ; Yang Liu ; Charles Z. Ding ; Qun Li ; Yasheen Zhou ; Jacob J. Plattner ; Stephen J. Baker ; Xuelei Qian ; Dazhong Fan ; Liang Liao ; Zhi-Jie Ni ; Gemma V. White ; Jackie E. Mordaunt ; Linos X. Lazarides ; Martin J. Slater ; Richard L. Jarvest ; Pia Thommes ; Malcolm Ellis ; Colin M. Edge ; Julia A. Hubbard ; Don Somers ; Paul Rowland ; Pamela Nassau ; Bill Mcdowell ; Tadeusz J. Skarzynski ; Wieslaw M. Kazmierski ; Richard M. Grimes ; Lois L. Wright ; Gary K. Smith ; Wuxin Zou ; Jon Wright ; Lewis E. Pennicott | Synthesis and evaluation of novel alpha-amino cyclic boronates as inhibitors of HCV NS3 protease. |
| 002144 (2010) |
R. Ramajayam [Taïwan] ; Kian-Pin Tan ; Hun-Ge Liu ; Po-Huang Liang | Synthesis, docking studies, and evaluation of pyrimidines as inhibitors of SARS-CoV 3CL protease. |
| 002324 (2011) |
Thi Thanh Hanh Nguyen [Corée du Sud] ; Hwa-Ja Ryu ; Se-Hoon Lee ; Soonwook Hwang ; Vincent Breton ; Joon Haeng Rhee ; Doman Kim | Virtual screening identification of novel severe acute respiratory syndrome 3C-like protease inhibitors and in vitro confirmation. |
| 002487 (2012) |
Li-Jun Wang [République populaire de Chine] ; Chang-An Geng ; Yun-Bao Ma ; Xiao-Yan Huang ; Jie Luo ; Hao Chen ; Xue-Mei Zhang ; Ji-Jun Chen | Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents. |
| 002499 (2012) |
Mi-Sun Yu [Corée du Sud] ; June Lee [Corée du Sud] ; Jin Moo Lee [Corée du Sud] ; Younggyu Kim [Corée du Sud] ; Young-Won Chin [Corée du Sud] ; Jun-Goo Jee [Corée du Sud] ; Young-Sam Keum [Corée du Sud] ; Yong-Joo Jeong [Corée du Sud] | Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13 |
| 002683 (2013) |
Sivakoteswara Rao Mandadapu [États-Unis] ; Pathum M. Weerawarna ; Allan M. Prior ; Roxanne Adeline Z. Uy ; Sridhar Aravapalli ; Kevin R. Alliston ; Gerald H. Lushington ; Yunjeong Kim ; Duy H. Hua ; Kyeong-Ok Chang ; William C. Groutas | Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus. |
| 002759 (2013) |
Mark Turlington [États-Unis] ; Aspen Chun ; Sakshi Tomar ; Aimee Eggler ; Valerie Grum-Tokars ; Jon Jacobs ; J Scott Daniels ; Eric Dawson ; Adrian Saldanha ; Peter Chase ; Yahira M. Baez-Santos ; Craig W. Lindsley ; Peter Hodder ; Andrew D. Mesecar ; Shaun R. Stauffer | Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. |
| 002873 (2014) |
Hao Chen [République populaire de Chine] ; Yun-Bao Ma [République populaire de Chine] ; Xiao-Yan Huang [République populaire de Chine] ; Chang-An Geng [République populaire de Chine] ; Yong Zhao [République populaire de Chine] ; Li-Jun Wang [République populaire de Chine] ; Rui-Hua Guo [République populaire de Chine] ; Wen-Juan Liang [République populaire de Chine] ; Xue-Mei Zhang [République populaire de Chine] ; Ji-Jun Chen [République populaire de Chine] | Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. |
| 002885 (2014) |
Bo Su [République populaire de Chine] ; Chunlong Cai [République populaire de Chine] ; Meng Deng [République populaire de Chine] ; Demin Liang [République populaire de Chine] ; Lizhong Wang [République populaire de Chine] ; Qingmin Wang [République populaire de Chine] | Design, synthesis, antiviral activity, and SARs of 13a-substituted phenanthroindolizidine alkaloid derivatives. |
| 002A42 (2015) |
Yong Zhao [République populaire de Chine] ; Chang-An Geng [République populaire de Chine] ; Hao Chen [République populaire de Chine] ; Yun-Bao Ma [République populaire de Chine] ; Xiao-Yan Huang [République populaire de Chine] ; Tuan-Wu Cao [République populaire de Chine] ; Kang He [République populaire de Chine] ; Hao Wang [République populaire de Chine] ; Xue-Mei Zhang [République populaire de Chine] ; Ji-Jun Chen [République populaire de Chine] | Isolation, synthesis and anti-hepatitis B virus evaluation of p-hydroxyacetophenone derivatives from Artemisia capillaris. |
| 002A43 (2015) |
Chang-An Geng [République populaire de Chine] ; Xiao-Yan Huang [République populaire de Chine] ; Yun-Bao Ma [République populaire de Chine] ; Xue-Mei Zhang [République populaire de Chine] ; Ji-Jun Chen [République populaire de Chine] | Synthesis of erythrocentaurin derivatives as a new class of hepatitis B virus inhibitors. |
| 002A84 (2015) |
Hannah L. Peters [États-Unis] ; Dirk Jochmans [Belgique] ; Adriaan H. De Wilde [Pays-Bas] ; Clara C. Posthuma [Pays-Bas] ; Eric J. Snijder [Pays-Bas] ; Johan Neyts [Belgique] ; Katherine L. Seley-Radtke [États-Unis] | Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity. |
