Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids
Identifieur interne : 002538 ( Ncbi/Checkpoint ); précédent : 002537; suivant : 002539Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids
Auteurs : Carmina Verdiá-Báguena [Espagne] ; Jose L. Nieto-Torres [Espagne] ; Antonio Alcaraz [Espagne] ; Marta L. Dediego [Espagne] ; Jaume Torres [Singapour] ; Vicente M. Aguilella [Espagne] ; Luis Enjuanes [Espagne]Source :
- Virology [ 0042-6822 ] ; 2012.
Descripteurs français
- KwdFr :
- Canaux ioniques (métabolisme), Coronavirus humain 229E (métabolisme), Données de séquences moléculaires, Humains, Lipides membranaires (métabolisme), Protéines de l'enveloppe virale (), Protéines de l'enveloppe virale (génétique), Protéines de l'enveloppe virale (métabolisme), Séquence d'acides aminés, Virus du SRAS (métabolisme).
- MESH :
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Viral Envelope Proteins.
- chemical , genetics : Viral Envelope Proteins.
- chemical , metabolism : Ion Channels, Membrane Lipids, Viral Envelope Proteins.
- metabolism : Coronavirus 229E, Human, SARS Virus.
- Amino Acid Sequence, Humans, Molecular Sequence Data.
Abstract
Coronavirus (CoV) envelope (E) protein ion channel activity was determined in channels formed in planar lipid bilayers by peptides representing either the transmembrane domain of severe acute respiratory syndrome CoV (SARS-CoV) E protein, or the full-length E protein. Both of them formed a voltage independent ion conductive pore with symmetric ion transport properties. Mutations N15A and V25F located in the transmembrane domain prevented the ion conductivity. E protein derived channels showed no cation preference in non-charged lipid membranes, whereas they behaved as pores with mild cation selectivity in negatively-charged lipid membranes. The ion conductance was also controlled by the lipid composition of the membrane. Lipid charge also regulated the selectivity of a HCoV-229E E protein derived peptide. These results suggested that the lipids are functionally involved in E protein ion channel activity, forming a protein–lipid pore, a novel concept for CoV E protein ion channel entity.
Url:
DOI: 10.1016/j.virol.2012.07.005
PubMed: 22832120
PubMed Central: 3438407
Affiliations:
- Espagne, Singapour
- Communauté de Madrid, Communauté valencienne
- Madrid
- Université autonome de Madrid
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PMC:3438407Le document en format XML
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Nieto-Torres</name><affiliation wicri:level="4"><nlm:aff id="aff2">Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region><settlement type="city">Madrid</settlement></placeName><orgName type="university">Université autonome de Madrid</orgName></affiliation></author><author><name sortKey="Alcaraz, Antonio" sort="Alcaraz, Antonio" uniqKey="Alcaraz A" first="Antonio" last="Alcaraz">Antonio Alcaraz</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Physics, Laboratory of Molecular Biophysics, Universitat Jaume I, 12071 Castellón, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Physics, Laboratory of Molecular Biophysics, Universitat Jaume I, 12071 Castellón</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté valencienne</region></placeName></affiliation></author><author><name sortKey="Dediego, Marta L" sort="Dediego, Marta L" uniqKey="Dediego M" first="Marta L." last="Dediego">Marta L. Dediego</name><affiliation wicri:level="4"><nlm:aff id="aff2">Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region><settlement type="city">Madrid</settlement></placeName><orgName type="university">Université autonome de Madrid</orgName></affiliation></author><author><name sortKey="Torres, Jaume" sort="Torres, Jaume" uniqKey="Torres J" first="Jaume" last="Torres">Jaume Torres</name><affiliation wicri:level="1"><nlm:aff id="aff3">School of Biological Sciences, Division of Structural and Computational Biology, Nanyang Technological University, Singapore 637551, Singapore</nlm:aff><country xml:lang="fr">Singapour</country><wicri:regionArea>School of Biological Sciences, Division of Structural and Computational Biology, Nanyang Technological University, Singapore 637551</wicri:regionArea><wicri:noRegion>Singapore 637551</wicri:noRegion></affiliation></author><author><name sortKey="Aguilella, Vicente M" sort="Aguilella, Vicente M" uniqKey="Aguilella V" first="Vicente M." last="Aguilella">Vicente M. Aguilella</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Physics, Laboratory of Molecular Biophysics, Universitat Jaume I, 12071 Castellón, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Physics, Laboratory of Molecular Biophysics, Universitat Jaume I, 12071 Castellón</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté valencienne</region></placeName></affiliation></author><author><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name><affiliation wicri:level="4"><nlm:aff id="aff2">Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid</wicri:regionArea><placeName><region nuts="2" type="communauté">Communauté de Madrid</region><settlement type="city">Madrid</settlement></placeName><orgName type="university">Université autonome de Madrid</orgName></affiliation></author></analytic><series><title level="j">Virology</title><idno type="ISSN">0042-6822</idno><idno type="eISSN">1096-0341</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino Acid Sequence</term><term>Coronavirus 229E, Human (metabolism)</term><term>Humans</term><term>Ion Channels (metabolism)</term><term>Membrane Lipids (metabolism)</term><term>Molecular Sequence Data</term><term>SARS Virus (metabolism)</term><term>Viral Envelope Proteins (chemistry)</term><term>Viral Envelope Proteins (genetics)</term><term>Viral Envelope Proteins (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Canaux ioniques (métabolisme)</term><term>Coronavirus humain 229E (métabolisme)</term><term>Données de séquences moléculaires</term><term>Humains</term><term>Lipides membranaires (métabolisme)</term><term>Protéines de l'enveloppe virale ()</term><term>Protéines de l'enveloppe virale (génétique)</term><term>Protéines de l'enveloppe virale (métabolisme)</term><term>Séquence d'acides aminés</term><term>Virus du SRAS (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Ion Channels</term><term>Membrane Lipids</term><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines de l'enveloppe virale</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Coronavirus 229E, Human</term><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Canaux ioniques</term><term>Coronavirus humain 229E</term><term>Lipides membranaires</term><term>Protéines de l'enveloppe virale</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term><term>Humans</term><term>Molecular Sequence Data</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Données de séquences moléculaires</term><term>Humains</term><term>Protéines de l'enveloppe virale</term><term>Séquence d'acides aminés</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Coronavirus (CoV) envelope (E) protein ion channel activity was determined in channels formed in planar lipid bilayers by peptides representing either the transmembrane domain of severe acute respiratory syndrome CoV (SARS-CoV) E protein, or the full-length E protein. Both of them formed a voltage independent ion conductive pore with symmetric ion transport properties. Mutations N15A and V25F located in the transmembrane domain prevented the ion conductivity. E protein derived channels showed no cation preference in non-charged lipid membranes, whereas they behaved as pores with mild cation selectivity in negatively-charged lipid membranes. The ion conductance was also controlled by the lipid composition of the membrane. Lipid charge also regulated the selectivity of a HCoV-229E E protein derived peptide. These results suggested that the lipids are functionally involved in E protein ion channel activity, forming a protein–lipid pore, a novel concept for CoV E protein ion channel entity.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Aguilella, V M" uniqKey="Aguilella V">V.M. Aguilella</name></author><author><name sortKey="Queralt Martin, M" uniqKey="Queralt Martin M">M. Queralt-Martin</name></author><author><name sortKey="Aguilella Arzo, M" uniqKey="Aguilella Arzo M">M. Aguilella-Arzo</name></author><author><name sortKey="Alcaraz, A" uniqKey="Alcaraz A">A. Alcaraz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alcaraz, A" uniqKey="Alcaraz A">A. Alcaraz</name></author><author><name sortKey="Nestorovich, E M" uniqKey="Nestorovich E">E.M. Nestorovich</name></author><author><name sortKey="Lopez, M L" uniqKey="Lopez M">M.L. Lopez</name></author><author><name sortKey="Garcia Gimenez, E" uniqKey="Garcia Gimenez E">E. Garcia-Gimenez</name></author><author><name sortKey="Bezrukov, S M" uniqKey="Bezrukov S">S.M. Bezrukov</name></author><author><name sortKey="Aguilella, V M" uniqKey="Aguilella V">V.M. Aguilella</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arbely, E" uniqKey="Arbely E">E. Arbely</name></author><author><name sortKey="Khattari, Z" uniqKey="Khattari Z">Z. Khattari</name></author><author><name sortKey="Brotons, G" uniqKey="Brotons G">G. Brotons</name></author><author><name sortKey="Akkawi, M" uniqKey="Akkawi M">M. Akkawi</name></author><author><name sortKey="Salditt, T" uniqKey="Salditt T">T. Salditt</name></author><author><name sortKey="Arkin, I T" uniqKey="Arkin I">I.T. Arkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bezrukov, S M" uniqKey="Bezrukov S">S.M. Bezrukov</name></author><author><name sortKey="Vodyanoy, I" uniqKey="Vodyanoy I">I. Vodyanoy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Campanella, M" uniqKey="Campanella M">M. Campanella</name></author><author><name sortKey="De Jong, A S" uniqKey="De Jong A">A.S. de Jong</name></author><author><name sortKey="Lanke, K W" uniqKey="Lanke K">K.W. Lanke</name></author><author><name sortKey="Melchers, W J" uniqKey="Melchers W">W.J. Melchers</name></author><author><name sortKey="Willems, P H" uniqKey="Willems P">P.H. Willems</name></author><author><name sortKey="Pinton, P" uniqKey="Pinton P">P. Pinton</name></author><author><name sortKey="Rizzuto, R" uniqKey="Rizzuto R">R. Rizzuto</name></author><author><name sortKey="Van Kuppeveld, F J" uniqKey="Van Kuppeveld F">F.J. van Kuppeveld</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, D K" uniqKey="Chu D">D.K. Chu</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corse, E" uniqKey="Corse E">E. Corse</name></author><author><name sortKey="Machamer, C E" uniqKey="Machamer C">C.E. Machamer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Groot, R J" uniqKey="De Groot R">R.J. de Groot</name></author><author><name sortKey="Baker, S C" uniqKey="Baker S">S.C. Baker</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author><author><name sortKey="Holmes, K V" uniqKey="Holmes K">K.V. Holmes</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Poon, L" uniqKey="Poon L">L. Poon</name></author><author><name sortKey="Rottier, P J M" uniqKey="Rottier P">P.J.M. Rottier</name></author><author><name sortKey="Talbot, P J" uniqKey="Talbot P">P.J. Talbot</name></author><author><name sortKey="Woo, P C Y" uniqKey="Woo P">P.C.Y. Woo</name></author><author><name sortKey="Ziebuhr, J" uniqKey="Ziebuhr J">J. Ziebuhr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Jong, A S" uniqKey="De Jong A">A.S. de Jong</name></author><author><name sortKey="Visch, H J" uniqKey="Visch H">H.J. Visch</name></author><author><name sortKey="De Mattia, F" uniqKey="De Mattia F">F. de Mattia</name></author><author><name sortKey="Van Dommelen, M M" uniqKey="Van Dommelen M">M.M. van Dommelen</name></author><author><name sortKey="Swarts, H G" uniqKey="Swarts H">H.G. Swarts</name></author><author><name sortKey="Luyten, T" uniqKey="Luyten T">T. Luyten</name></author><author><name sortKey="Callewaert, G" uniqKey="Callewaert G">G. Callewaert</name></author><author><name sortKey="Melchers, W J" uniqKey="Melchers W">W.J. Melchers</name></author><author><name sortKey="Willems, P H" uniqKey="Willems P">P.H. Willems</name></author><author><name sortKey="Van Kuppeveld, F J" uniqKey="Van Kuppeveld F">F.J. van Kuppeveld</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. DeDiego</name></author><author><name sortKey="Alvarez, E" uniqKey="Alvarez E">E. Alvarez</name></author><author><name sortKey="Almazan, F" uniqKey="Almazan F">F. Almazan</name></author><author><name sortKey="Rejas, M T" uniqKey="Rejas M">M.T. Rejas</name></author><author><name sortKey="Lamirande, E" uniqKey="Lamirande E">E. Lamirande</name></author><author><name sortKey="Roberts, A" uniqKey="Roberts A">A. Roberts</name></author><author><name sortKey="Shieh, W J" uniqKey="Shieh W">W.J. Shieh</name></author><author><name sortKey="Zaki, S R" uniqKey="Zaki S">S.R. Zaki</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. DeDiego</name></author><author><name sortKey="Nieto Torres, J L" uniqKey="Nieto Torres J">J.L. Nieto-Torres</name></author><author><name sortKey="Jimenez Guardeno, J M" uniqKey="Jimenez Guardeno J">J.M. Jimenez-Guardeno</name></author><author><name sortKey="Regla Nava, J A" uniqKey="Regla Nava J">J.A. Regla-Nava</name></author><author><name sortKey="Alvarez, E" uniqKey="Alvarez E">E. Alvarez</name></author><author><name sortKey="Oliveros, J C" uniqKey="Oliveros J">J.C. Oliveros</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Fett, C" uniqKey="Fett C">C. Fett</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. DeDiego</name></author><author><name sortKey="Pewe, L" uniqKey="Pewe L">L. Pewe</name></author><author><name sortKey="Alvarez, E" uniqKey="Alvarez E">E. Alvarez</name></author><author><name sortKey="Rejas, M T" uniqKey="Rejas M">M.T. Rejas</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author><author><name sortKey="Gloza Rausch, F" uniqKey="Gloza Rausch F">F. Gloza-Rausch</name></author><author><name sortKey="Glende, J" uniqKey="Glende J">J. Glende</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Muth, D" uniqKey="Muth D">D. Muth</name></author><author><name sortKey="Goettsche, M" uniqKey="Goettsche M">M. Goettsche</name></author><author><name sortKey="Seebens, A" uniqKey="Seebens A">A. Seebens</name></author><author><name sortKey="Niedrig, M" uniqKey="Niedrig M">M. Niedrig</name></author><author><name sortKey="Pfefferle, S" uniqKey="Pfefferle S">S. Pfefferle</name></author><author><name sortKey="Yordanov, S" uniqKey="Yordanov S">S. Yordanov</name></author><author><name sortKey="Zhelyazkov, L" uniqKey="Zhelyazkov L">L. Zhelyazkov</name></author><author><name sortKey="Hermanns, U" uniqKey="Hermanns U">U. Hermanns</name></author><author><name sortKey="Vallo, P" uniqKey="Vallo P">P. Vallo</name></author><author><name sortKey="Lukashev, A" uniqKey="Lukashev A">A. Lukashev</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Muller</name></author><author><name sortKey="Deng, H" uniqKey="Deng H">H. Deng</name></author><author><name sortKey="Herrler, G" uniqKey="Herrler G">G. Herrler</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Gunther, S" uniqKey="Gunther S">S. Gunther</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W. Preiser</name></author><author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S. van der Werf</name></author><author><name sortKey="Brodt, H R" uniqKey="Brodt H">H.R. Brodt</name></author><author><name sortKey="Becker, S" uniqKey="Becker S">S. Becker</name></author><author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H. Rabenau</name></author><author><name sortKey="Panning, M" uniqKey="Panning M">M. Panning</name></author><author><name sortKey="Kolesnikova, L" uniqKey="Kolesnikova L">L. Kolesnikova</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Berger, A" uniqKey="Berger A">A. Berger</name></author><author><name sortKey="Burguiere, A M" uniqKey="Burguiere A">A.M. Burguiere</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J. Cinatl</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M. Eickmann</name></author><author><name sortKey="Escriou, N" uniqKey="Escriou N">N. Escriou</name></author><author><name sortKey="Grywna, K" uniqKey="Grywna K">K. Grywna</name></author><author><name sortKey="Kramme, S" uniqKey="Kramme S">S. Kramme</name></author><author><name sortKey="Manuguerra, J C" uniqKey="Manuguerra J">J.C. Manuguerra</name></author><author><name sortKey="Muller, S" uniqKey="Muller S">S. Muller</name></author><author><name sortKey="Rickerts, V" uniqKey="Rickerts V">V. Rickerts</name></author><author><name sortKey="Sturmer, M" uniqKey="Sturmer M">M. Sturmer</name></author><author><name sortKey="Vieth, S" uniqKey="Vieth S">S. Vieth</name></author><author><name sortKey="Klenk, H D" uniqKey="Klenk H">H.D. Klenk</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Schmitz, H" uniqKey="Schmitz H">H. Schmitz</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eleftheriou, D" uniqKey="Eleftheriou D">D. Eleftheriou</name></author><author><name sortKey="Melo, M" uniqKey="Melo M">M. Melo</name></author><author><name sortKey="Marks, S D" uniqKey="Marks S">S.D. Marks</name></author><author><name sortKey="Tullus, K" uniqKey="Tullus K">K. Tullus</name></author><author><name sortKey="Sills, J" uniqKey="Sills J">J. Sills</name></author><author><name sortKey="Cleary, G" uniqKey="Cleary G">G. Cleary</name></author><author><name sortKey="Dolezalova, P" uniqKey="Dolezalova P">P. Dolezalova</name></author><author><name sortKey="Ozen, S" uniqKey="Ozen S">S. Ozen</name></author><author><name sortKey="Pilkington, C" uniqKey="Pilkington C">C. Pilkington</name></author><author><name sortKey="Woo, P" uniqKey="Woo P">P. Woo</name></author><author><name sortKey="Klein, N" uniqKey="Klein N">N. Klein</name></author><author><name sortKey="Dillon, M J" uniqKey="Dillon M">M.J. Dillon</name></author><author><name sortKey="Brogan, P A" uniqKey="Brogan P">P.A. Brogan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author><author><name sortKey="De Groot, R J" uniqKey="De Groot R">R.J. de Groot</name></author><author><name sortKey="Cowley, J A" uniqKey="Cowley J">J.A. Cowley</name></author><author><name sortKey="Ziebuhr, J" uniqKey="Ziebuhr J">J. Ziebuhr</name></author><author><name sortKey="Snijder, E J" uniqKey="Snijder E">E.J. Snijder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ewart, G D" uniqKey="Ewart G">G.D. Ewart</name></author><author><name sortKey="Sutherland, T" uniqKey="Sutherland T">T. Sutherland</name></author><author><name sortKey="Gage, P W" uniqKey="Gage P">P.W. Gage</name></author><author><name sortKey="Cox, G B" uniqKey="Cox G">G.B. Cox</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hall, J E" uniqKey="Hall J">J.E. Hall</name></author><author><name sortKey="Vodyanoy, I" uniqKey="Vodyanoy I">I. Vodyanoy</name></author><author><name sortKey="Balasubramanian, T M" uniqKey="Balasubramanian T">T.M. Balasubramanian</name></author><author><name sortKey="Marshall, G R" uniqKey="Marshall G">G.R. Marshall</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hille, B" uniqKey="Hille B">B. Hille</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hodgkin, A L" uniqKey="Hodgkin A">A.L. Hodgkin</name></author><author><name sortKey="Katz, B" uniqKey="Katz B">B. Katz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Ito, N" uniqKey="Ito N">N. Ito</name></author><author><name sortKey="Tseng, C T" uniqKey="Tseng C">C.T. Tseng</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Peters, C J" uniqKey="Peters C">C.J. Peters</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ichinohe, T" uniqKey="Ichinohe T">T. Ichinohe</name></author><author><name sortKey="Pang, I K" uniqKey="Pang I">I.K. Pang</name></author><author><name sortKey="Iwasaki, A" uniqKey="Iwasaki A">A. Iwasaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuo, L" uniqKey="Kuo L">L. Kuo</name></author><author><name sortKey="Hurst, K R" uniqKey="Hurst K">K.R. Hurst</name></author><author><name sortKey="Masters, P S" uniqKey="Masters P">P.S. Masters</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuo, L" uniqKey="Kuo L">L. Kuo</name></author><author><name sortKey="Masters, P S" uniqKey="Masters P">P.S. Masters</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lim, K P" uniqKey="Lim K">K.P. Lim</name></author><author><name sortKey="Liu, D X" uniqKey="Liu D">D.X. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maeda, J" uniqKey="Maeda J">J. Maeda</name></author><author><name sortKey="Repass, J F" uniqKey="Repass J">J.F. Repass</name></author><author><name sortKey="Maeda, A" uniqKey="Maeda A">A. Maeda</name></author><author><name sortKey="Makino, S" uniqKey="Makino S">S. Makino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Malev, V V" uniqKey="Malev V">V.V. Malev</name></author><author><name sortKey="Schagina, L V" uniqKey="Schagina L">L.V. Schagina</name></author><author><name sortKey="Gurnev, P A" uniqKey="Gurnev P">P.A. Gurnev</name></author><author><name sortKey="Takemoto, J Y" uniqKey="Takemoto J">J.Y. Takemoto</name></author><author><name sortKey="Nestorovich, E M" uniqKey="Nestorovich E">E.M. Nestorovich</name></author><author><name sortKey="Bezrukov, S M" uniqKey="Bezrukov S">S.M. Bezrukov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Montal, M" uniqKey="Montal M">M. Montal</name></author><author><name sortKey="Mueller, P" uniqKey="Mueller P">P. Mueller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Muller</name></author><author><name sortKey="Paweska, J T" uniqKey="Paweska J">J.T. Paweska</name></author><author><name sortKey="Leman, P A" uniqKey="Leman P">P.A. Leman</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Grywna, K" uniqKey="Grywna K">K. Grywna</name></author><author><name sortKey="Kemp, A" uniqKey="Kemp A">A. Kemp</name></author><author><name sortKey="Braack, L" uniqKey="Braack L">L. Braack</name></author><author><name sortKey="Sonnenberg, K" uniqKey="Sonnenberg K">K. Sonnenberg</name></author><author><name sortKey="Niedrig, M" uniqKey="Niedrig M">M. Niedrig</name></author><author><name sortKey="Swanepoel, R" uniqKey="Swanepoel R">R. Swanepoel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nal, B" uniqKey="Nal B">B. Nal</name></author><author><name sortKey="Chan, C" uniqKey="Chan C">C. Chan</name></author><author><name sortKey="Kien, F" uniqKey="Kien F">F. Kien</name></author><author><name sortKey="Siu, L" uniqKey="Siu L">L. Siu</name></author><author><name sortKey="Tse, J" uniqKey="Tse J">J. Tse</name></author><author><name sortKey="Chu, K" uniqKey="Chu K">K. Chu</name></author><author><name sortKey="Kam, J" uniqKey="Kam J">J. Kam</name></author><author><name sortKey="Staropoli, I" uniqKey="Staropoli I">I. Staropoli</name></author><author><name sortKey="Crescenzo Chaigne, B" uniqKey="Crescenzo Chaigne B">B. Crescenzo-Chaigne</name></author><author><name sortKey="Escriou, N" uniqKey="Escriou N">N. Escriou</name></author><author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S. van der Werf</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Altmeyer, R" uniqKey="Altmeyer R">R. Altmeyer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Netland, J" uniqKey="Netland J">J. Netland</name></author><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. DeDiego</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J. Zhao</name></author><author><name sortKey="Fett, C" uniqKey="Fett C">C. Fett</name></author><author><name sortKey="Alvarez, E" uniqKey="Alvarez E">E. Alvarez</name></author><author><name sortKey="Nieto Torres, J L" uniqKey="Nieto Torres J">J.L. Nieto-Torres</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nguyen, V P" uniqKey="Nguyen V">V.P. Nguyen</name></author><author><name sortKey="Hogue, B G" uniqKey="Hogue B">B.G. Hogue</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nieto Torres, J L" uniqKey="Nieto Torres J">J.L. Nieto-Torres</name></author><author><name sortKey="Dediego, M L" uniqKey="Dediego M">M.L. Dediego</name></author><author><name sortKey="Alvarez, E" uniqKey="Alvarez E">E. Alvarez</name></author><author><name sortKey="Jimenez Guardeno, J M" uniqKey="Jimenez Guardeno J">J.M. Jimenez-Guardeno</name></author><author><name sortKey="Regla Nava, J A" uniqKey="Regla Nava J">J.A. Regla-Nava</name></author><author><name sortKey="Llorente, M" uniqKey="Llorente M">M. Llorente</name></author><author><name sortKey="Kremer, L" uniqKey="Kremer L">L. Kremer</name></author><author><name sortKey="Shuo, S" uniqKey="Shuo S">S. Shuo</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oren, Z" uniqKey="Oren Z">Z. Oren</name></author><author><name sortKey="Shai, Y" uniqKey="Shai Y">Y. Shai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ortego, J" uniqKey="Ortego J">J. Ortego</name></author><author><name sortKey="Ceriani, J E" uniqKey="Ceriani J">J.E. Ceriani</name></author><author><name sortKey="Patino, C" uniqKey="Patino C">C. Patino</name></author><author><name sortKey="Plana, J" uniqKey="Plana J">J. Plana</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ortego, J" uniqKey="Ortego J">J. Ortego</name></author><author><name sortKey="Escors, D" uniqKey="Escors D">D. Escors</name></author><author><name sortKey="Laude, H" uniqKey="Laude H">H. Laude</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Netland, J" uniqKey="Netland J">J. Netland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pervushin, K" uniqKey="Pervushin K">K. Pervushin</name></author><author><name sortKey="Tan, E" uniqKey="Tan E">E. Tan</name></author><author><name sortKey="Parthasarathy, K" uniqKey="Parthasarathy K">K. Parthasarathy</name></author><author><name sortKey="Lin, X" uniqKey="Lin X">X. Lin</name></author><author><name sortKey="Jiang, F L" uniqKey="Jiang F">F.L. Jiang</name></author><author><name sortKey="Yu, D" uniqKey="Yu D">D. Yu</name></author><author><name sortKey="Vararattanavech, A" uniqKey="Vararattanavech A">A. Vararattanavech</name></author><author><name sortKey="Soong, T W" uniqKey="Soong T">T.W. Soong</name></author><author><name sortKey="Liu, D X" uniqKey="Liu D">D.X. Liu</name></author><author><name sortKey="Torres, J" uniqKey="Torres J">J. Torres</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pinto, L H" uniqKey="Pinto L">L.H. Pinto</name></author><author><name sortKey="Holsinger, L J" uniqKey="Holsinger L">L.J. Holsinger</name></author><author><name sortKey="Lamb, R A" uniqKey="Lamb R">R.A. Lamb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Quan, P L" uniqKey="Quan P">P.L. Quan</name></author><author><name sortKey="Firth, C" uniqKey="Firth C">C. Firth</name></author><author><name sortKey="Street, C" uniqKey="Street C">C. Street</name></author><author><name sortKey="Henriquez, J A" uniqKey="Henriquez J">J.A. Henriquez</name></author><author><name sortKey="Petrosov, A" uniqKey="Petrosov A">A. Petrosov</name></author><author><name sortKey="Tashmukhamedova, A" uniqKey="Tashmukhamedova A">A. Tashmukhamedova</name></author><author><name sortKey="Hutchison, S K" uniqKey="Hutchison S">S.K. Hutchison</name></author><author><name sortKey="Egholm, M" uniqKey="Egholm M">M. Egholm</name></author><author><name sortKey="Osinubi, M O" uniqKey="Osinubi M">M.O. Osinubi</name></author><author><name sortKey="Niezgoda, M" uniqKey="Niezgoda M">M. Niezgoda</name></author><author><name sortKey="Ogunkoya, A B" uniqKey="Ogunkoya A">A.B. Ogunkoya</name></author><author><name sortKey="Briese, T" uniqKey="Briese T">T. Briese</name></author><author><name sortKey="Rupprecht, C E" uniqKey="Rupprecht C">C.E. Rupprecht</name></author><author><name sortKey="Lipkin, W I" uniqKey="Lipkin W">W.I. Lipkin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Raamsman, M J B" uniqKey="Raamsman M">M.J.B. Raamsman</name></author><author><name sortKey="Locker, J K" uniqKey="Locker J">J.K. Locker</name></author><author><name sortKey="De Hooge, A" uniqKey="De Hooge A">A. de Hooge</name></author><author><name sortKey="De Vries, A A F" uniqKey="De Vries A">A.A.F. de Vries</name></author><author><name sortKey="Griffiths, G" uniqKey="Griffiths G">G. Griffiths</name></author><author><name sortKey="Vennema, H" uniqKey="Vennema H">H. Vennema</name></author><author><name sortKey="Rottier, P J M" uniqKey="Rottier P">P.J.M. Rottier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rota, P A" uniqKey="Rota P">P.A. Rota</name></author><author><name sortKey="Oberste, M S" uniqKey="Oberste M">M.S. Oberste</name></author><author><name sortKey="Monroe, S S" uniqKey="Monroe S">S.S. Monroe</name></author><author><name sortKey="Nix, W A" uniqKey="Nix W">W.A. Nix</name></author><author><name sortKey="Campganoli, R" uniqKey="Campganoli R">R. Campganoli</name></author><author><name sortKey="Icenogle, J P" uniqKey="Icenogle J">J.P. Icenogle</name></author><author><name sortKey="Pe Aranda, S" uniqKey="Pe Aranda S">S. Peñaranda</name></author><author><name sortKey="Bankamp, B" uniqKey="Bankamp B">B. Bankamp</name></author><author><name sortKey="Maher, K" uniqKey="Maher K">K. Maher</name></author><author><name sortKey="Chen, M H" uniqKey="Chen M">M.-H. Chen</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author><author><name sortKey="Tamin, A" uniqKey="Tamin A">A. Tamin</name></author><author><name sortKey="Lowe, L" uniqKey="Lowe L">L. Lowe</name></author><author><name sortKey="Frace, M" uniqKey="Frace M">M. Frace</name></author><author><name sortKey="Derisi, J L" uniqKey="Derisi J">J.L. DeRisi</name></author><author><name sortKey="Chen, Q" uniqKey="Chen Q">Q. Chen</name></author><author><name sortKey="Wang, D" uniqKey="Wang D">D. Wang</name></author><author><name sortKey="Erdman, D D" uniqKey="Erdman D">D.d. Erdman</name></author><author><name sortKey="Peret, T C T" uniqKey="Peret T">T.C.T. Peret</name></author><author><name sortKey="Burns, C" uniqKey="Burns C">C. Burns</name></author><author><name sortKey="Ksiazek, T G" uniqKey="Ksiazek T">T.G. Ksiazek</name></author><author><name sortKey="Rollin, P E" uniqKey="Rollin P">P.E. Rollin</name></author><author><name sortKey="Sanchez, A" uniqKey="Sanchez A">A. Sanchez</name></author><author><name sortKey="Liffick, S" uniqKey="Liffick S">S. Liffick</name></author><author><name sortKey="Holloway, B" uniqKey="Holloway B">B. Holloway</name></author><author><name sortKey="Limor, J" uniqKey="Limor J">J. Limor</name></author><author><name sortKey="Mccaustland, K" uniqKey="Mccaustland K">K. McCaustland</name></author><author><name sortKey="Olsen Rassmussen, M" uniqKey="Olsen Rassmussen M">M. Olsen-Rassmussen</name></author><author><name sortKey="Fouchier, R" uniqKey="Fouchier R">R. Fouchier</name></author><author><name sortKey="Gunther, S" uniqKey="Gunther S">S. Gunther</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A.D.M.E. Osterhaus</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Pallansch, M A" uniqKey="Pallansch M">M.A. Pallansch</name></author><author><name sortKey="Anderson, L J" uniqKey="Anderson L">L.J. Anderson</name></author><author><name sortKey="Bellini, W J" uniqKey="Bellini W">W.J. Bellini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ruch, T R" uniqKey="Ruch T">T.R. Ruch</name></author><author><name sortKey="Machamer, C E" uniqKey="Machamer C">C.E. Machamer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ruch, T R" uniqKey="Ruch T">T.R. Ruch</name></author><author><name sortKey="Machamer, C E" uniqKey="Machamer C">C.E. Machamer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ruch, T R" uniqKey="Ruch T">T.R. Ruch</name></author><author><name sortKey="Machamer, C E" uniqKey="Machamer C">C.E. Machamer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sani, M A" uniqKey="Sani M">M.A. Sani</name></author><author><name sortKey="Whitwell, T C" uniqKey="Whitwell T">T.C. Whitwell</name></author><author><name sortKey="Separovic, F" uniqKey="Separovic F">F. Separovic</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schaecher, S R" uniqKey="Schaecher S">S.R. Schaecher</name></author><author><name sortKey="Mackenzie, J M" uniqKey="Mackenzie J">J.M. Mackenzie</name></author><author><name sortKey="Pekosz, A" uniqKey="Pekosz A">A. Pekosz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shen, S" uniqKey="Shen S">S. Shen</name></author><author><name sortKey="Lin, P S" uniqKey="Lin P">P.S. Lin</name></author><author><name sortKey="Chao, Y C" uniqKey="Chao Y">Y.C. Chao</name></author><author><name sortKey="Zhang, A" uniqKey="Zhang A">A. Zhang</name></author><author><name sortKey="Yang, X" uniqKey="Yang X">X. Yang</name></author><author><name sortKey="Lim, S G" uniqKey="Lim S">S.G. Lim</name></author><author><name sortKey="Hong, W" uniqKey="Hong W">W. Hong</name></author><author><name sortKey="Tan, Y J" uniqKey="Tan Y">Y.J. Tan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sobko, A A" uniqKey="Sobko A">A.A. Sobko</name></author><author><name sortKey="Kotova, E A" uniqKey="Kotova E">E.A. Kotova</name></author><author><name sortKey="Antonenko, Y N" uniqKey="Antonenko Y">Y.N. Antonenko</name></author><author><name sortKey="Zakharov, S D" uniqKey="Zakharov S">S.D. Zakharov</name></author><author><name sortKey="Cramer, W A" uniqKey="Cramer W">W.A. Cramer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Teoh, K T" uniqKey="Teoh K">K.T. Teoh</name></author><author><name sortKey="Siu, Y L" uniqKey="Siu Y">Y.L. Siu</name></author><author><name sortKey="Chan, W L" uniqKey="Chan W">W.L. Chan</name></author><author><name sortKey="Schluter, M A" uniqKey="Schluter M">M.A. Schluter</name></author><author><name sortKey="Liu, C J" uniqKey="Liu C">C.J. Liu</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Bruzzone, R" uniqKey="Bruzzone R">R. Bruzzone</name></author><author><name sortKey="Margolis, B" uniqKey="Margolis B">B. Margolis</name></author><author><name sortKey="Nal, B" uniqKey="Nal B">B. Nal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Torres, J" uniqKey="Torres J">J. Torres</name></author><author><name sortKey="Maheswari, U" uniqKey="Maheswari U">U. Maheswari</name></author><author><name sortKey="Parthasarathy, K" uniqKey="Parthasarathy K">K. Parthasarathy</name></author><author><name sortKey="Ng, L" uniqKey="Ng L">L. Ng</name></author><author><name sortKey="Liu, D X" uniqKey="Liu D">D.X. Liu</name></author><author><name sortKey="Gong, X" uniqKey="Gong X">X. Gong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Torres, J" uniqKey="Torres J">J. Torres</name></author><author><name sortKey="Parthasarathy, K" uniqKey="Parthasarathy K">K. Parthasarathy</name></author><author><name sortKey="Lin, X" uniqKey="Lin X">X. Lin</name></author><author><name sortKey="Saravanan, R" uniqKey="Saravanan R">R. Saravanan</name></author><author><name sortKey="Liu, D X" uniqKey="Liu D">D.X. Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Meer, G" uniqKey="Van Meer G">G. van Meer</name></author><author><name sortKey="Voelker, D R" uniqKey="Voelker D">D.R. Voelker</name></author><author><name sortKey="Feigenson, G W" uniqKey="Feigenson G">G.W. Feigenson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, L" uniqKey="Wilson L">L. Wilson</name></author><author><name sortKey="Gage, P" uniqKey="Gage P">P. Gage</name></author><author><name sortKey="Ewart, G" uniqKey="Ewart G">G. Ewart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, L" uniqKey="Wilson L">L. Wilson</name></author><author><name sortKey="Mckinlay, C" uniqKey="Mckinlay C">C. McKinlay</name></author><author><name sortKey="Gage, P" uniqKey="Gage P">P. Gage</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wozniak, A L" uniqKey="Wozniak A">A.L. Wozniak</name></author><author><name sortKey="Griffin, S" uniqKey="Griffin S">S. Griffin</name></author><author><name sortKey="Rowlands, D" uniqKey="Rowlands D">D. Rowlands</name></author><author><name sortKey="Harris, M" uniqKey="Harris M">M. Harris</name></author><author><name sortKey="Yi, M" uniqKey="Yi M">M. Yi</name></author><author><name sortKey="Lemon, S M" uniqKey="Lemon S">S.M. Lemon</name></author><author><name sortKey="Weinman, S A" uniqKey="Weinman S">S.A. Weinman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ye, Y" uniqKey="Ye Y">Y. Ye</name></author><author><name sortKey="Hogue, B G" uniqKey="Hogue B">B.G. Hogue</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Espagne</li><li>Singapour</li></country><region><li>Communauté de Madrid</li><li>Communauté valencienne</li></region><settlement><li>Madrid</li></settlement><orgName><li>Université autonome de Madrid</li></orgName></list><tree><country name="Espagne"><region name="Communauté valencienne"><name sortKey="Verdia Baguena, Carmina" sort="Verdia Baguena, Carmina" uniqKey="Verdia Baguena C" first="Carmina" last="Verdiá-Báguena">Carmina Verdiá-Báguena</name></region><name sortKey="Aguilella, Vicente M" sort="Aguilella, Vicente M" uniqKey="Aguilella V" first="Vicente M." last="Aguilella">Vicente M. Aguilella</name><name sortKey="Alcaraz, Antonio" sort="Alcaraz, Antonio" uniqKey="Alcaraz A" first="Antonio" last="Alcaraz">Antonio Alcaraz</name><name sortKey="Dediego, Marta L" sort="Dediego, Marta L" uniqKey="Dediego M" first="Marta L." last="Dediego">Marta L. Dediego</name><name sortKey="Enjuanes, Luis" sort="Enjuanes, Luis" uniqKey="Enjuanes L" first="Luis" last="Enjuanes">Luis Enjuanes</name><name sortKey="Nieto Torres, Jose L" sort="Nieto Torres, Jose L" uniqKey="Nieto Torres J" first="Jose L." last="Nieto-Torres">Jose L. Nieto-Torres</name></country><country name="Singapour"><noRegion><name sortKey="Torres, Jaume" sort="Torres, Jaume" uniqKey="Torres J" first="Jaume" last="Torres">Jaume Torres</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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