A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo
Identifieur interne : 002017 ( Ncbi/Checkpoint ); précédent : 002016; suivant : 002018A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo
Auteurs : Craig W. Day [États-Unis] ; Ralph Baric [États-Unis] ; Sui Xiong Cai [États-Unis] ; Matt Frieman [États-Unis] ; Yohichi Kumaki [États-Unis] ; John D. Morrey [États-Unis] ; Donald F. Smee [États-Unis] ; Dale L. Barnard [États-Unis]Source :
- Virology [ 0042-6822 ] ; 2009.
Descripteurs français
- KwdFr :
- Animaux, Antiviraux (pharmacologie), Cytokines (métabolisme), Femelle, Génome viral, Mutation, Poumon (anatomopathologie), Poumon (métabolisme), Protéines virales (génétique), Protéines virales (métabolisme), Régulation de l'expression des gènes (physiologie), Souris, Souris de lignée BALB C, Syndrome respiratoire aigu sévère (métabolisme), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (physiologie).
- MESH :
- anatomopathologie : Poumon.
- génétique : Protéines virales.
- métabolisme : Cytokines, Poumon, Protéines virales, Syndrome respiratoire aigu sévère.
- pharmacologie : Antiviraux.
- physiologie : Régulation de l'expression des gènes, Virus du SRAS.
- traitement médicamenteux : Syndrome respiratoire aigu sévère.
- virologie : Syndrome respiratoire aigu sévère.
- Animaux, Femelle, Génome viral, Mutation, Souris, Souris de lignée BALB C.
English descriptors
- KwdEn :
- Animals, Antiviral Agents (pharmacology), Cytokines (metabolism), Female, Gene Expression Regulation (physiology), Genome, Viral, Lung (metabolism), Lung (pathology), Mice, Mice, Inbred BALB C, Mutation, SARS Virus (physiology), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (metabolism), Severe Acute Respiratory Syndrome (virology), Viral Proteins (genetics), Viral Proteins (metabolism).
- MESH :
- chemical , genetics : Viral Proteins.
- chemical , metabolism : Cytokines, Viral Proteins.
- chemical , pharmacology : Antiviral Agents.
- drug therapy : Severe Acute Respiratory Syndrome.
- metabolism : Lung, Severe Acute Respiratory Syndrome.
- pathology : Lung.
- physiology : Gene Expression Regulation, SARS Virus.
- virology : Severe Acute Respiratory Syndrome.
- Animals, Female, Genome, Viral, Mice, Mice, Inbred BALB C, Mutation.
Abstract
Severe acute respiratory syndrome (SARS) is a highly lethal emerging disease caused by coronavirus SARS-CoV. New lethal animal models for SARS were needed to facilitate antiviral research. We adapted and characterized a new strain of SARS-CoV (strain v2163) that was highly lethal in 5- to 6-week-old BALB/c mice. It had nine mutations affecting 10 amino acid residues. Strain v2163 increased IL-1α, IL-6, MIP-1α, MCP-1, and RANTES in mice, and high IL-6 expression correlated with mortality. The infection largely mimicked human disease, but lung pathology lacked hyaline membrane formation. In vitro efficacy against v2163 was shown with known inhibitors of SARS-CoV replication. In v2163-infected mice, Ampligen™ was fully protective, stinging nettle lectin (UDA) was partially protective, ribavirin was disputable and possibly exacerbated disease, and EP128533 was inactive. Ribavirin, UDA, and Ampligen™ decreased IL-6 expression. Strain v2163 provided a valuable model for anti-SARS research.
Url:
DOI: 10.1016/j.virol.2009.09.023
PubMed: 19853271
PubMed Central: 2787736
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001542
- to stream Pmc, to step Curation: 001542
- to stream Pmc, to step Checkpoint: 000D55
- to stream PubMed, to step Corpus: 001810
- to stream PubMed, to step Curation: 001810
- to stream PubMed, to step Checkpoint: 001955
- to stream Ncbi, to step Merge: 002017
- to stream Ncbi, to step Curation: 002017
Links to Exploration step
PMC:2787736Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo</title><author><name sortKey="Day, Craig W" sort="Day, Craig W" uniqKey="Day C" first="Craig W." last="Day">Craig W. Day</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name><affiliation wicri:level="2"><nlm:aff id="aff2">Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Cai, Sui Xiong" sort="Cai, Sui Xiong" uniqKey="Cai S" first="Sui Xiong" last="Cai">Sui Xiong Cai</name><affiliation wicri:level="2"><nlm:aff id="aff4">Epicept Corporation, 6650 Nancy Ridge Drive, San Diego, CA 92121, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epicept Corporation, 6650 Nancy Ridge Drive, San Diego, CA 92121</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Frieman, Matt" sort="Frieman, Matt" uniqKey="Frieman M" first="Matt" last="Frieman">Matt Frieman</name><affiliation wicri:level="2"><nlm:aff id="aff3">University of North Carolina, 3105 Hooker Research Center, Chapel Hill, NC 27713, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of North Carolina, 3105 Hooker Research Center, Chapel Hill, NC 27713</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Kumaki, Yohichi" sort="Kumaki, Yohichi" uniqKey="Kumaki Y" first="Yohichi" last="Kumaki">Yohichi Kumaki</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Morrey, John D" sort="Morrey, John D" uniqKey="Morrey J" first="John D." last="Morrey">John D. Morrey</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Smee, Donald F" sort="Smee, Donald F" uniqKey="Smee D" first="Donald F." last="Smee">Donald F. Smee</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Barnard, Dale L" sort="Barnard, Dale L" uniqKey="Barnard D" first="Dale L." last="Barnard">Dale L. Barnard</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">19853271</idno><idno type="pmc">2787736</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787736</idno><idno type="RBID">PMC:2787736</idno><idno type="doi">10.1016/j.virol.2009.09.023</idno><date when="2009">2009</date><idno type="wicri:Area/Pmc/Corpus">001542</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001542</idno><idno type="wicri:Area/Pmc/Curation">001542</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001542</idno><idno type="wicri:Area/Pmc/Checkpoint">000D55</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000D55</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:19853271</idno><idno type="wicri:Area/PubMed/Corpus">001810</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001810</idno><idno type="wicri:Area/PubMed/Curation">001810</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001810</idno><idno type="wicri:Area/PubMed/Checkpoint">001955</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001955</idno><idno type="wicri:Area/Ncbi/Merge">002017</idno><idno type="wicri:Area/Ncbi/Curation">002017</idno><idno type="wicri:Area/Ncbi/Checkpoint">002017</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo</title><author><name sortKey="Day, Craig W" sort="Day, Craig W" uniqKey="Day C" first="Craig W." last="Day">Craig W. Day</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name><affiliation wicri:level="2"><nlm:aff id="aff2">Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Cai, Sui Xiong" sort="Cai, Sui Xiong" uniqKey="Cai S" first="Sui Xiong" last="Cai">Sui Xiong Cai</name><affiliation wicri:level="2"><nlm:aff id="aff4">Epicept Corporation, 6650 Nancy Ridge Drive, San Diego, CA 92121, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Epicept Corporation, 6650 Nancy Ridge Drive, San Diego, CA 92121</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Frieman, Matt" sort="Frieman, Matt" uniqKey="Frieman M" first="Matt" last="Frieman">Matt Frieman</name><affiliation wicri:level="2"><nlm:aff id="aff3">University of North Carolina, 3105 Hooker Research Center, Chapel Hill, NC 27713, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of North Carolina, 3105 Hooker Research Center, Chapel Hill, NC 27713</wicri:regionArea><placeName><region type="state">Caroline du Nord</region></placeName></affiliation></author><author><name sortKey="Kumaki, Yohichi" sort="Kumaki, Yohichi" uniqKey="Kumaki Y" first="Yohichi" last="Kumaki">Yohichi Kumaki</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Morrey, John D" sort="Morrey, John D" uniqKey="Morrey J" first="John D." last="Morrey">John D. Morrey</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Smee, Donald F" sort="Smee, Donald F" uniqKey="Smee D" first="Donald F." last="Smee">Donald F. Smee</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Barnard, Dale L" sort="Barnard, Dale L" uniqKey="Barnard D" first="Dale L." last="Barnard">Dale L. Barnard</name><affiliation wicri:level="2"><nlm:aff id="aff1">Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Institute for Antiviral Research, Utah State University, UMC 5600, Logan, UT 84322-5600</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author></analytic><series><title level="j">Virology</title><idno type="ISSN">0042-6822</idno><idno type="eISSN">1096-0341</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Antiviral Agents (pharmacology)</term><term>Cytokines (metabolism)</term><term>Female</term><term>Gene Expression Regulation (physiology)</term><term>Genome, Viral</term><term>Lung (metabolism)</term><term>Lung (pathology)</term><term>Mice</term><term>Mice, Inbred BALB C</term><term>Mutation</term><term>SARS Virus (physiology)</term><term>Severe Acute Respiratory Syndrome (drug therapy)</term><term>Severe Acute Respiratory Syndrome (metabolism)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Viral Proteins (genetics)</term><term>Viral Proteins (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Antiviraux (pharmacologie)</term><term>Cytokines (métabolisme)</term><term>Femelle</term><term>Génome viral</term><term>Mutation</term><term>Poumon (anatomopathologie)</term><term>Poumon (métabolisme)</term><term>Protéines virales (génétique)</term><term>Protéines virales (métabolisme)</term><term>Régulation de l'expression des gènes (physiologie)</term><term>Souris</term><term>Souris de lignée BALB C</term><term>Syndrome respiratoire aigu sévère (métabolisme)</term><term>Syndrome respiratoire aigu sévère (traitement médicamenteux)</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Virus du SRAS (physiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Viral Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Cytokines</term><term>Viral Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antiviral Agents</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Poumon</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines virales</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lung</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cytokines</term><term>Poumon</term><term>Protéines virales</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lung</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Antiviraux</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Régulation de l'expression des gènes</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Gene Expression Regulation</term><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Female</term><term>Genome, Viral</term><term>Mice</term><term>Mice, Inbred BALB C</term><term>Mutation</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Femelle</term><term>Génome viral</term><term>Mutation</term><term>Souris</term><term>Souris de lignée BALB C</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Severe acute respiratory syndrome (SARS) is a highly lethal emerging disease caused by coronavirus SARS-CoV. New lethal animal models for SARS were needed to facilitate antiviral research. We adapted and characterized a new strain of SARS-CoV (strain v2163) that was highly lethal in 5- to 6-week-old BALB/c mice. It had nine mutations affecting 10 amino acid residues. Strain v2163 increased IL-1α, IL-6, MIP-1α, MCP-1, and RANTES in mice, and high IL-6 expression correlated with mortality. The infection largely mimicked human disease, but lung pathology lacked hyaline membrane formation. In vitro efficacy against v2163 was shown with known inhibitors of SARS-CoV replication. In v2163-infected mice, Ampligen™ was fully protective, stinging nettle lectin (UDA) was partially protective, ribavirin was disputable and possibly exacerbated disease, and EP128533 was inactive. Ribavirin, UDA, and Ampligen™ decreased IL-6 expression. Strain v2163 provided a valuable model for anti-SARS research.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Balzarini, J" uniqKey="Balzarini J">J. Balzarini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barnard, D L" uniqKey="Barnard D">D.L. Barnard</name></author><author><name sortKey="Day, C W" uniqKey="Day C">C.W. Day</name></author><author><name sortKey="Bailey, K" uniqKey="Bailey K">K. Bailey</name></author><author><name sortKey="Heiner, M" uniqKey="Heiner M">M. Heiner</name></author><author><name sortKey="Montgomery, R" uniqKey="Montgomery R">R. Montgomery</name></author><author><name sortKey="Lauridsen, L" uniqKey="Lauridsen L">L. Lauridsen</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barnard, D L" uniqKey="Barnard D">D.L. Barnard</name></author><author><name sortKey="Day, C W" uniqKey="Day C">C.W. Day</name></author><author><name sortKey="Bailey, K" uniqKey="Bailey K">K. Bailey</name></author><author><name sortKey="Heiner, M" uniqKey="Heiner M">M. Heiner</name></author><author><name sortKey="Montgomery, R" uniqKey="Montgomery R">R. Montgomery</name></author><author><name sortKey="Lauridsen, L" uniqKey="Lauridsen L">L. Lauridsen</name></author><author><name sortKey="Jung, K H" uniqKey="Jung K">K.H. Jung</name></author><author><name sortKey="Li, J K" uniqKey="Li J">J.K. Li</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barnard, D L" uniqKey="Barnard D">D.L. Barnard</name></author><author><name sortKey="Day, C W" uniqKey="Day C">C.W. Day</name></author><author><name sortKey="Bailey, K" uniqKey="Bailey K">K. Bailey</name></author><author><name sortKey="Heiner, M" uniqKey="Heiner M">M. Heiner</name></author><author><name sortKey="Montgomery, R" uniqKey="Montgomery R">R. Montgomery</name></author><author><name sortKey="Lauridsen, L" uniqKey="Lauridsen L">L. Lauridsen</name></author><author><name sortKey="Winslow, S" uniqKey="Winslow S">S. Winslow</name></author><author><name sortKey="Hoopes, J" uniqKey="Hoopes J">J. Hoopes</name></author><author><name sortKey="Li, J K" uniqKey="Li J">J.K. Li</name></author><author><name sortKey="Lee, J" uniqKey="Lee J">J. Lee</name></author><author><name sortKey="Carson, D A" uniqKey="Carson D">D.A. Carson</name></author><author><name sortKey="Cottam, H B" uniqKey="Cottam H">H.B. Cottam</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barnard, D L" uniqKey="Barnard D">D.L. Barnard</name></author><author><name sortKey="Hubbard, V D" uniqKey="Hubbard V">V.D. Hubbard</name></author><author><name sortKey="Burton, J" uniqKey="Burton J">J. Burton</name></author><author><name sortKey="Smee, D F" uniqKey="Smee D">D.F. Smee</name></author><author><name sortKey="Morrey, J D" uniqKey="Morrey J">J.D. Morrey</name></author><author><name sortKey="Otto, M J" uniqKey="Otto M">M.J. Otto</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Becker, M M" uniqKey="Becker M">M.M. Becker</name></author><author><name sortKey="Graham, R L" uniqKey="Graham R">R.L. Graham</name></author><author><name sortKey="Donaldson, E F" uniqKey="Donaldson E">E.F. Donaldson</name></author><author><name sortKey="Rockx, B" uniqKey="Rockx B">B. Rockx</name></author><author><name sortKey="Sims, A C" uniqKey="Sims A">A.C. Sims</name></author><author><name sortKey="Sheahan, T" uniqKey="Sheahan T">T. Sheahan</name></author><author><name sortKey="Pickles, R J" uniqKey="Pickles R">R.J. Pickles</name></author><author><name sortKey="Corti, D" uniqKey="Corti D">D. Corti</name></author><author><name sortKey="Johnston, R E" uniqKey="Johnston R">R.E. Johnston</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author><author><name sortKey="Denison, M R" uniqKey="Denison M">M.R. Denison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cameron, M J" uniqKey="Cameron M">M.J. Cameron</name></author><author><name sortKey="Bermejo Martin, J F" uniqKey="Bermejo Martin J">J.F. Bermejo-Martin</name></author><author><name sortKey="Danesh, A" uniqKey="Danesh A">A. Danesh</name></author><author><name sortKey="Muller, M P" uniqKey="Muller M">M.P. Muller</name></author><author><name sortKey="Kelvin, D J" uniqKey="Kelvin D">D.J. Kelvin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carter, W A" uniqKey="Carter W">W.A. Carter</name></author><author><name sortKey="Pitha, P M" uniqKey="Pitha P">P.M. Pitha</name></author><author><name sortKey="Marshall, L W" uniqKey="Marshall L">L.W. Marshall</name></author><author><name sortKey="Tazawa, I" uniqKey="Tazawa I">I. Tazawa</name></author><author><name sortKey="Tazawa, S" uniqKey="Tazawa S">S. Tazawa</name></author><author><name sortKey="Ts O, P O" uniqKey="Ts O P">P.O. Ts'o</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, J" uniqKey="Chen J">J. Chen</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheung, O Y" uniqKey="Cheung O">O.Y. Cheung</name></author><author><name sortKey="Chan, J W" uniqKey="Chan J">J.W. Chan</name></author><author><name sortKey="Ng, C K" uniqKey="Ng C">C.K. Ng</name></author><author><name sortKey="Koo, C K" uniqKey="Koo C">C.K. Koo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chowers, M Y" uniqKey="Chowers M">M.Y. Chowers</name></author><author><name sortKey="Lang, R" uniqKey="Lang R">R. Lang</name></author><author><name sortKey="Nassar, F" uniqKey="Nassar F">F. Nassar</name></author><author><name sortKey="Ben David, D" uniqKey="Ben David D">D. Ben-David</name></author><author><name sortKey="Giladi, M" uniqKey="Giladi M">M. Giladi</name></author><author><name sortKey="Rubinshtein, E" uniqKey="Rubinshtein E">E. Rubinshtein</name></author><author><name sortKey="Itzhaki, A" uniqKey="Itzhaki A">A. Itzhaki</name></author><author><name sortKey="Mishal, J" uniqKey="Mishal J">J. Mishal</name></author><author><name sortKey="Siegman Igra, Y" uniqKey="Siegman Igra Y">Y. Siegman-Igra</name></author><author><name sortKey="Kitzes, R" uniqKey="Kitzes R">R. Kitzes</name></author><author><name sortKey="Pick, N" uniqKey="Pick N">N. Pick</name></author><author><name sortKey="Landau, Z" uniqKey="Landau Z">Z. Landau</name></author><author><name sortKey="Wolf, D" uniqKey="Wolf D">D. Wolf</name></author><author><name sortKey="Bin, H" uniqKey="Bin H">H. Bin</name></author><author><name sortKey="Mendelson, E" uniqKey="Mendelson E">E. Mendelson</name></author><author><name sortKey="Pitlik, S D" uniqKey="Pitlik S">S.D. Pitlik</name></author><author><name sortKey="Weinberger, M" uniqKey="Weinberger M">M. Weinberger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, Y K" uniqKey="Chu Y">Y.-K. Chu</name></author><author><name sortKey="Ali, G D" uniqKey="Ali G">G.D. Ali</name></author><author><name sortKey="Jia, F" uniqKey="Jia F">F. Jia</name></author><author><name sortKey="Li, Q" uniqKey="Li Q">Q. Li</name></author><author><name sortKey="Kelvin, D" uniqKey="Kelvin D">D. Kelvin</name></author><author><name sortKey="Couch, R C" uniqKey="Couch R">R.C. Couch</name></author><author><name sortKey="Harrod, K S" uniqKey="Harrod K">K.S. Harrod</name></author><author><name sortKey="Hutt, J A" uniqKey="Hutt J">J.A. Hutt</name></author><author><name sortKey="Cameron, C" uniqKey="Cameron C">C. Cameron</name></author><author><name sortKey="Weiss, S R" uniqKey="Weiss S">S.R. Weiss</name></author><author><name sortKey="Jonsson, C B" uniqKey="Jonsson C">C.B. Jonsson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J. Cinatl</name></author><author><name sortKey="Morgenstern, B" uniqKey="Morgenstern B">B. Morgenstern</name></author><author><name sortKey="Bauer, G" uniqKey="Bauer G">G. Bauer</name></author><author><name sortKey="Chandra, P" uniqKey="Chandra P">P. Chandra</name></author><author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H. Rabenau</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Clercq, E" uniqKey="De Clercq E">E. De Clercq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ding, Y" uniqKey="Ding Y">Y. Ding</name></author><author><name sortKey="He, L" uniqKey="He L">L. He</name></author><author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q. Zhang</name></author><author><name sortKey="Huang, Z" uniqKey="Huang Z">Z. Huang</name></author><author><name sortKey="Che, X" uniqKey="Che X">X. Che</name></author><author><name sortKey="Hou, J" uniqKey="Hou J">J. Hou</name></author><author><name sortKey="Wang, H" uniqKey="Wang H">H. Wang</name></author><author><name sortKey="Shen, H" uniqKey="Shen H">H. Shen</name></author><author><name sortKey="Qiu, L" uniqKey="Qiu L">L. Qiu</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z. Li</name></author><author><name sortKey="Geng, J" uniqKey="Geng J">J. Geng</name></author><author><name sortKey="Cai, J" uniqKey="Cai J">J. Cai</name></author><author><name sortKey="Han, H" uniqKey="Han H">H. Han</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Kang, W" uniqKey="Kang W">W. Kang</name></author><author><name sortKey="Weng, D" uniqKey="Weng D">D. Weng</name></author><author><name sortKey="Liang, P" uniqKey="Liang P">P. Liang</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Gunther, S" uniqKey="Gunther S">S. Gunther</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W. Preiser</name></author><author><name sortKey="Van Der Werf, S" uniqKey="Van Der Werf S">S. van der Werf</name></author><author><name sortKey="Brodt, H R" uniqKey="Brodt H">H.R. Brodt</name></author><author><name sortKey="Becker, S" uniqKey="Becker S">S. Becker</name></author><author><name sortKey="Rabenau, H" uniqKey="Rabenau H">H. Rabenau</name></author><author><name sortKey="Panning, M" uniqKey="Panning M">M. Panning</name></author><author><name sortKey="Kolesnikova, L" uniqKey="Kolesnikova L">L. Kolesnikova</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Berger, A" uniqKey="Berger A">A. Berger</name></author><author><name sortKey="Burguiere, A M" uniqKey="Burguiere A">A.M. Burguiere</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J. Cinatl</name></author><author><name sortKey="Eickmann, M" uniqKey="Eickmann M">M. Eickmann</name></author><author><name sortKey="Escriou, N" uniqKey="Escriou N">N. Escriou</name></author><author><name sortKey="Grywna, K" uniqKey="Grywna K">K. Grywna</name></author><author><name sortKey="Kramme, S" uniqKey="Kramme S">S. Kramme</name></author><author><name sortKey="Manuguerra, J C" uniqKey="Manuguerra J">J.C. Manuguerra</name></author><author><name sortKey="Muller, S" uniqKey="Muller S">S. Muller</name></author><author><name sortKey="Rickerts, V" uniqKey="Rickerts V">V. Rickerts</name></author><author><name sortKey="Sturmer, M" uniqKey="Sturmer M">M. Sturmer</name></author><author><name sortKey="Vieth, S" uniqKey="Vieth S">S. Vieth</name></author><author><name sortKey="Klenk, H D" uniqKey="Klenk H">H.D. Klenk</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Schmitz, H" uniqKey="Schmitz H">H. Schmitz</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W. Preiser</name></author><author><name sortKey="Gunther, S" uniqKey="Gunther S">S. Gunther</name></author><author><name sortKey="Schmitz, H" uniqKey="Schmitz H">H. Schmitz</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Du, L" uniqKey="Du L">L. Du</name></author><author><name sortKey="He, Y" uniqKey="He Y">Y. He</name></author><author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y. Zhou</name></author><author><name sortKey="Liu, S" uniqKey="Liu S">S. Liu</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="Jiang, S" uniqKey="Jiang S">S. Jiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Finter, N B" uniqKey="Finter N">N.B. Finter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T. Kuiken</name></author><author><name sortKey="Schutten, M" uniqKey="Schutten M">M. Schutten</name></author><author><name sortKey="Van Amerongen, G" uniqKey="Van Amerongen G">G. van Amerongen</name></author><author><name sortKey="Van Doornum, G J" uniqKey="Van Doornum G">G.J. van Doornum</name></author><author><name sortKey="Van Den Hoogen, B G" uniqKey="Van Den Hoogen B">B.G. van den Hoogen</name></author><author><name sortKey="Peiris, M" uniqKey="Peiris M">M. Peiris</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Stohr, K" uniqKey="Stohr K">K. Stohr</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Franks, T J" uniqKey="Franks T">T.J. Franks</name></author><author><name sortKey="Chong, P Y" uniqKey="Chong P">P.Y. Chong</name></author><author><name sortKey="Chui, P" uniqKey="Chui P">P. Chui</name></author><author><name sortKey="Galvin, J R" uniqKey="Galvin J">J.R. Galvin</name></author><author><name sortKey="Lourens, R M" uniqKey="Lourens R">R.M. Lourens</name></author><author><name sortKey="Reid, A H" uniqKey="Reid A">A.H. Reid</name></author><author><name sortKey="Selbs, E" uniqKey="Selbs E">E. Selbs</name></author><author><name sortKey="Mcevoy, C P" uniqKey="Mcevoy C">C.P. McEvoy</name></author><author><name sortKey="Hayden, C D" uniqKey="Hayden C">C.D. Hayden</name></author><author><name sortKey="Fukuoka, J" uniqKey="Fukuoka J">J. Fukuoka</name></author><author><name sortKey="Taubenberger, J K" uniqKey="Taubenberger J">J.K. Taubenberger</name></author><author><name sortKey="Travis, W D" uniqKey="Travis W">W.D. Travis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Frieman, M" uniqKey="Frieman M">M. Frieman</name></author><author><name sortKey="Heise, M" uniqKey="Heise M">M. Heise</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Glass, W G" uniqKey="Glass W">W.G. Glass</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author><author><name sortKey="Murphy, B" uniqKey="Murphy B">B. Murphy</name></author><author><name sortKey="Murphy, P M" uniqKey="Murphy P">P.M. Murphy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gowen, B B" uniqKey="Gowen B">B.B. Gowen</name></author><author><name sortKey="Hoopes, J D" uniqKey="Hoopes J">J.D. Hoopes</name></author><author><name sortKey="Wong, M H" uniqKey="Wong M">M.H. Wong</name></author><author><name sortKey="Jung, K H" uniqKey="Jung K">K.H. Jung</name></author><author><name sortKey="Isakson, K C" uniqKey="Isakson K">K.C. Isakson</name></author><author><name sortKey="Alexopoulou, L" uniqKey="Alexopoulou L">L. Alexopoulou</name></author><author><name sortKey="Flavell, R A" uniqKey="Flavell R">R.A. Flavell</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gowen, B B" uniqKey="Gowen B">B.B. Gowen</name></author><author><name sortKey="Wong, M H" uniqKey="Wong M">M.H. Wong</name></author><author><name sortKey="Jung, K H" uniqKey="Jung K">K.H. Jung</name></author><author><name sortKey="Sanders, A B" uniqKey="Sanders A">A.B. Sanders</name></author><author><name sortKey="Mitchell, W M" uniqKey="Mitchell W">W.M. Mitchell</name></author><author><name sortKey="Alexopoulou, L" uniqKey="Alexopoulou L">L. Alexopoulou</name></author><author><name sortKey="Flavell, R A" uniqKey="Flavell R">R.A. Flavell</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greenough, T C" uniqKey="Greenough T">T.C. Greenough</name></author><author><name sortKey="Carville, A" uniqKey="Carville A">A. Carville</name></author><author><name sortKey="Coderre, J" uniqKey="Coderre J">J. Coderre</name></author><author><name sortKey="Somasundaran, M" uniqKey="Somasundaran M">M. Somasundaran</name></author><author><name sortKey="Sullivan, J L" uniqKey="Sullivan J">J.L. Sullivan</name></author><author><name sortKey="Luzuriaga, K" uniqKey="Luzuriaga K">K. Luzuriaga</name></author><author><name sortKey="Mansfield, K" uniqKey="Mansfield K">K. Mansfield</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="He, Y Q" uniqKey="He Y">Y.Q. He</name></author><author><name sortKey="Liu, X L" uniqKey="Liu X">X.L. Liu</name></author><author><name sortKey="Zhuang, Z X" uniqKey="Zhuang Z">Z.X. Zhuang</name></author><author><name sortKey="Cheung, C L" uniqKey="Cheung C">C.L. Cheung</name></author><author><name sortKey="Luo, S W" uniqKey="Luo S">S.W. Luo</name></author><author><name sortKey="Li, P H" uniqKey="Li P">P.H. Li</name></author><author><name sortKey="Zhang, L J" uniqKey="Zhang L">L.J. Zhang</name></author><author><name sortKey="Guan, Y J" uniqKey="Guan Y">Y.J. Guan</name></author><author><name sortKey="Butt, K M" uniqKey="Butt K">K.M. Butt</name></author><author><name sortKey="Wong, K L" uniqKey="Wong K">K.L. Wong</name></author><author><name sortKey="Chan, K W" uniqKey="Chan K">K.W. Chan</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Shortridge, K F" uniqKey="Shortridge K">K.F. Shortridge</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, Y" uniqKey="Guo Y">Y. Guo</name></author><author><name sortKey="Korteweg, C" uniqKey="Korteweg C">C. Korteweg</name></author><author><name sortKey="Mcnutt, M A" uniqKey="Mcnutt M">M.A. McNutt</name></author><author><name sortKey="Gu, J" uniqKey="Gu J">J. Gu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hegde, S" uniqKey="Hegde S">S. Hegde</name></author><author><name sortKey="Pahne, J" uniqKey="Pahne J">J. Pahne</name></author><author><name sortKey="Smola Hess, S" uniqKey="Smola Hess S">S. Smola-Hess</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hon, C C" uniqKey="Hon C">C.C. Hon</name></author><author><name sortKey="Lam, T Y" uniqKey="Lam T">T.Y. Lam</name></author><author><name sortKey="Shi, Z L" uniqKey="Shi Z">Z.L. Shi</name></author><author><name sortKey="Drummond, A J" uniqKey="Drummond A">A.J. Drummond</name></author><author><name sortKey="Yip, C W" uniqKey="Yip C">C.W. Yip</name></author><author><name sortKey="Zeng, F" uniqKey="Zeng F">F. Zeng</name></author><author><name sortKey="Lam, P Y" uniqKey="Lam P">P.Y. Lam</name></author><author><name sortKey="Leung, F C" uniqKey="Leung F">F.C. Leung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsiao, C H" uniqKey="Hsiao C">C.H. Hsiao</name></author><author><name sortKey="Wu, M Z" uniqKey="Wu M">M.Z. Wu</name></author><author><name sortKey="Chen, C L" uniqKey="Chen C">C.L. Chen</name></author><author><name sortKey="Hsueh, P R" uniqKey="Hsueh P">P.R. Hsueh</name></author><author><name sortKey="Hsieh, S W" uniqKey="Hsieh S">S.W. Hsieh</name></author><author><name sortKey="Yang, P C" uniqKey="Yang P">P.C. Yang</name></author><author><name sortKey="Su, I J" uniqKey="Su I">I.J. Su</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsueh, P R" uniqKey="Hsueh P">P.R. Hsueh</name></author><author><name sortKey="Chen, P J" uniqKey="Chen P">P.J. Chen</name></author><author><name sortKey="Hsiao, C H" uniqKey="Hsiao C">C.H. Hsiao</name></author><author><name sortKey="Yeh, S H" uniqKey="Yeh S">S.H. Yeh</name></author><author><name sortKey="Cheng, W C" uniqKey="Cheng W">W.C. Cheng</name></author><author><name sortKey="Wang, J L" uniqKey="Wang J">J.L. Wang</name></author><author><name sortKey="Chiang, B L" uniqKey="Chiang B">B.L. Chiang</name></author><author><name sortKey="Chang, S C" uniqKey="Chang S">S.C. Chang</name></author><author><name sortKey="Chang, F Y" uniqKey="Chang F">F.Y. Chang</name></author><author><name sortKey="Wong, W W" uniqKey="Wong W">W.W. Wong</name></author><author><name sortKey="Kao, C L" uniqKey="Kao C">C.L. Kao</name></author><author><name sortKey="Yang, P C" uniqKey="Yang P">P.C. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, Y H" uniqKey="Huang Y">Y.H. Huang</name></author><author><name sortKey="Lei, H Y" uniqKey="Lei H">H.Y. Lei</name></author><author><name sortKey="Liu, H S" uniqKey="Liu H">H.S. Liu</name></author><author><name sortKey="Lin, Y S" uniqKey="Lin Y">Y.S. Lin</name></author><author><name sortKey="Liu, C C" uniqKey="Liu C">C.C. Liu</name></author><author><name sortKey="Yeh, T M" uniqKey="Yeh T">T.M. Yeh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hultgren, C" uniqKey="Hultgren C">C. Hultgren</name></author><author><name sortKey="Milich, D R" uniqKey="Milich D">D.R. Milich</name></author><author><name sortKey="Weiland, O" uniqKey="Weiland O">O. Weiland</name></author><author><name sortKey="Sallberg, M" uniqKey="Sallberg M">M. Sallberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jiang, Y" uniqKey="Jiang Y">Y. Jiang</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J. Xu</name></author><author><name sortKey="Zhou, C" uniqKey="Zhou C">C. Zhou</name></author><author><name sortKey="Wu, Z" uniqKey="Wu Z">Z. Wu</name></author><author><name sortKey="Zhong, S" uniqKey="Zhong S">S. Zhong</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J. Liu</name></author><author><name sortKey="Luo, W" uniqKey="Luo W">W. Luo</name></author><author><name sortKey="Chen, T" uniqKey="Chen T">T. Chen</name></author><author><name sortKey="Qin, Q" uniqKey="Qin Q">Q. Qin</name></author><author><name sortKey="Deng, P" uniqKey="Deng P">P. Deng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jiang, Z" uniqKey="Jiang Z">Z. Jiang</name></author><author><name sortKey="Kunimoto, M" uniqKey="Kunimoto M">M. Kunimoto</name></author><author><name sortKey="Patel, J A" uniqKey="Patel J">J.A. Patel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, B M" uniqKey="Jones B">B.M. Jones</name></author><author><name sortKey="Ma, E S" uniqKey="Ma E">E.S. Ma</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Wong, P C" uniqKey="Wong P">P.C. Wong</name></author><author><name sortKey="Ho, J C" uniqKey="Ho J">J.C. Ho</name></author><author><name sortKey="Lam, B" uniqKey="Lam B">B. Lam</name></author><author><name sortKey="Lai, K N" uniqKey="Lai K">K.N. Lai</name></author><author><name sortKey="Tsang, K W" uniqKey="Tsang K">K.W. Tsang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Julander, J G" uniqKey="Julander J">J.G. Julander</name></author><author><name sortKey="Skirpstunas, R" uniqKey="Skirpstunas R">R. Skirpstunas</name></author><author><name sortKey="Siddharthan, V" uniqKey="Siddharthan V">V. Siddharthan</name></author><author><name sortKey="Shafer, K" uniqKey="Shafer K">K. Shafer</name></author><author><name sortKey="Hoopes, J D" uniqKey="Hoopes J">J.D. Hoopes</name></author><author><name sortKey="Smee, D F" uniqKey="Smee D">D.F. Smee</name></author><author><name sortKey="Morrey, J D" uniqKey="Morrey J">J.D. Morrey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keyaerts, E" uniqKey="Keyaerts E">E. Keyaerts</name></author><author><name sortKey="Vijgen, L" uniqKey="Vijgen L">L. Vijgen</name></author><author><name sortKey="Pannecouque, C" uniqKey="Pannecouque C">C. Pannecouque</name></author><author><name sortKey="Van Damme, E" uniqKey="Van Damme E">E. Van Damme</name></author><author><name sortKey="Peumans, W" uniqKey="Peumans W">W. Peumans</name></author><author><name sortKey="Egberink, H" uniqKey="Egberink H">H. Egberink</name></author><author><name sortKey="Balzarini, J" uniqKey="Balzarini J">J. Balzarini</name></author><author><name sortKey="Van Ranst, M" uniqKey="Van Ranst M">M. Van Ranst</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kopf, M" uniqKey="Kopf M">M. Kopf</name></author><author><name sortKey="Baumann, H" uniqKey="Baumann H">H. Baumann</name></author><author><name sortKey="Freer, G" uniqKey="Freer G">G. Freer</name></author><author><name sortKey="Freudenberg, M" uniqKey="Freudenberg M">M. Freudenberg</name></author><author><name sortKey="Lamers, M" uniqKey="Lamers M">M. Lamers</name></author><author><name sortKey="Kishimoto, T" uniqKey="Kishimoto T">T. Kishimoto</name></author><author><name sortKey="Zinkernagel, R" uniqKey="Zinkernagel R">R. Zinkernagel</name></author><author><name sortKey="Bluethmann, H" uniqKey="Bluethmann H">H. Bluethmann</name></author><author><name sortKey="Kohler, G" uniqKey="Kohler G">G. Kohler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ksiazek, T G" uniqKey="Ksiazek T">T.G. Ksiazek</name></author><author><name sortKey="Erdman, D" uniqKey="Erdman D">D. Erdman</name></author><author><name sortKey="Goldsmith, C S" uniqKey="Goldsmith C">C.S. Goldsmith</name></author><author><name sortKey="Zaki, S R" uniqKey="Zaki S">S.R. Zaki</name></author><author><name sortKey="Peret, T" uniqKey="Peret T">T. Peret</name></author><author><name sortKey="Emery, S" uniqKey="Emery S">S. Emery</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author><author><name sortKey="Urbani, C" uniqKey="Urbani C">C. Urbani</name></author><author><name sortKey="Comer, J A" uniqKey="Comer J">J.A. Comer</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Rollin, P E" uniqKey="Rollin P">P.E. Rollin</name></author><author><name sortKey="Dowell, S F" uniqKey="Dowell S">S.F. Dowell</name></author><author><name sortKey="Ling, A E" uniqKey="Ling A">A.E. Ling</name></author><author><name sortKey="Humphrey, C D" uniqKey="Humphrey C">C.D. Humphrey</name></author><author><name sortKey="Shieh, W J" uniqKey="Shieh W">W.J. Shieh</name></author><author><name sortKey="Guarner, J" uniqKey="Guarner J">J. Guarner</name></author><author><name sortKey="Paddock, C D" uniqKey="Paddock C">C.D. Paddock</name></author><author><name sortKey="Rota, P" uniqKey="Rota P">P. Rota</name></author><author><name sortKey="Fields, B" uniqKey="Fields B">B. Fields</name></author><author><name sortKey="Derisi, J" uniqKey="Derisi J">J. DeRisi</name></author><author><name sortKey="Yang, J Y" uniqKey="Yang J">J.Y. Yang</name></author><author><name sortKey="Cox, N" uniqKey="Cox N">N. Cox</name></author><author><name sortKey="Hughes, J M" uniqKey="Hughes J">J.M. Hughes</name></author><author><name sortKey="Leduc, J W" uniqKey="Leduc J">J.W. LeDuc</name></author><author><name sortKey="Bellini, W J" uniqKey="Bellini W">W.J. Bellini</name></author><author><name sortKey="Anderson, L J" uniqKey="Anderson L">L.J. Anderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kumaki, Y" uniqKey="Kumaki Y">Y. Kumaki</name></author><author><name sortKey="Day, C W" uniqKey="Day C">C.W. Day</name></author><author><name sortKey="Wandersee, M K" uniqKey="Wandersee M">M.K. Wandersee</name></author><author><name sortKey="Schow, B P" uniqKey="Schow B">B.P. Schow</name></author><author><name sortKey="Madsen, J S" uniqKey="Madsen J">J.S. Madsen</name></author><author><name sortKey="Grant, D" uniqKey="Grant D">D. Grant</name></author><author><name sortKey="Roth, J P" uniqKey="Roth J">J.P. Roth</name></author><author><name sortKey="Smee, D F" uniqKey="Smee D">D.F. Smee</name></author><author><name sortKey="Blatt, L M" uniqKey="Blatt L">L.M. Blatt</name></author><author><name sortKey="Barnard, D L" uniqKey="Barnard D">D.L. Barnard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuri, T" uniqKey="Kuri T">T. Kuri</name></author><author><name sortKey="Zhang, X" uniqKey="Zhang X">X. Zhang</name></author><author><name sortKey="Habjan, M" uniqKey="Habjan M">M. Habjan</name></author><author><name sortKey="Martinez Sobrido, L" uniqKey="Martinez Sobrido L">L. Martinez-Sobrido</name></author><author><name sortKey="Garcia Sastre, A" uniqKey="Garcia Sastre A">A. Garcia-Sastre</name></author><author><name sortKey="Yuan, Z" uniqKey="Yuan Z">Z. Yuan</name></author><author><name sortKey="Weber, F" uniqKey="Weber F">F. Weber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kurt Jones, E A" uniqKey="Kurt Jones E">E.A. Kurt-Jones</name></author><author><name sortKey="Belko, J" uniqKey="Belko J">J. Belko</name></author><author><name sortKey="Yu, C" uniqKey="Yu C">C. Yu</name></author><author><name sortKey="Newburger, P E" uniqKey="Newburger P">P.E. Newburger</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Chan, M" uniqKey="Chan M">M. Chan</name></author><author><name sortKey="Knipe, D M" uniqKey="Knipe D">D.M. Knipe</name></author><author><name sortKey="Finberg, R W" uniqKey="Finberg R">R.W. Finberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lang, Z" uniqKey="Lang Z">Z. Lang</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Meng, X" uniqKey="Meng X">X. Meng</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Song, C" uniqKey="Song C">C. Song</name></author><author><name sortKey="Sun, L" uniqKey="Sun L">L. Sun</name></author><author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y. Zhou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leyssen, P" uniqKey="Leyssen P">P. Leyssen</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Paning, M" uniqKey="Paning M">M. Paning</name></author><author><name sortKey="Charlier, N" uniqKey="Charlier N">N. Charlier</name></author><author><name sortKey="Paeshuyse, J" uniqKey="Paeshuyse J">J. Paeshuyse</name></author><author><name sortKey="De Clercq, E" uniqKey="De Clercq E">E. De Clercq</name></author><author><name sortKey="Neyts, J" uniqKey="Neyts J">J. Neyts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, F" uniqKey="Li F">F. Li</name></author><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Farzan, M" uniqKey="Farzan M">M. Farzan</name></author><author><name sortKey="Harrison, S C" uniqKey="Harrison S">S.C. Harrison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Moore, M J" uniqKey="Moore M">M.J. Moore</name></author><author><name sortKey="Vasilieva, N" uniqKey="Vasilieva N">N. Vasilieva</name></author><author><name sortKey="Sui, J" uniqKey="Sui J">J. Sui</name></author><author><name sortKey="Wong, S K" uniqKey="Wong S">S.K. Wong</name></author><author><name sortKey="Berne, M A" uniqKey="Berne M">M.A. Berne</name></author><author><name sortKey="Somasundaran, M" uniqKey="Somasundaran M">M. Somasundaran</name></author><author><name sortKey="Sullivan, J L" uniqKey="Sullivan J">J.L. Sullivan</name></author><author><name sortKey="Luzuriaga, K" uniqKey="Luzuriaga K">K. Luzuriaga</name></author><author><name sortKey="Greenough, T C" uniqKey="Greenough T">T.C. Greenough</name></author><author><name sortKey="Choe, H" uniqKey="Choe H">H. Choe</name></author><author><name sortKey="Farzan, M" uniqKey="Farzan M">M. Farzan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Shi, Z" uniqKey="Shi Z">Z. Shi</name></author><author><name sortKey="Yu, M" uniqKey="Yu M">M. Yu</name></author><author><name sortKey="Ren, W" uniqKey="Ren W">W. Ren</name></author><author><name sortKey="Smith, C" uniqKey="Smith C">C. Smith</name></author><author><name sortKey="Epstein, J H" uniqKey="Epstein J">J.H. Epstein</name></author><author><name sortKey="Wang, H" uniqKey="Wang H">H. Wang</name></author><author><name sortKey="Crameri, G" uniqKey="Crameri G">G. Crameri</name></author><author><name sortKey="Hu, Z" uniqKey="Hu Z">Z. Hu</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H. Zhang</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Mceachern, J" uniqKey="Mceachern J">J. McEachern</name></author><author><name sortKey="Field, H" uniqKey="Field H">H. Field</name></author><author><name sortKey="Daszak, P" uniqKey="Daszak P">P. Daszak</name></author><author><name sortKey="Eaton, B T" uniqKey="Eaton B">B.T. Eaton</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Wang, L F" uniqKey="Wang L">L.F. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martina, B E" uniqKey="Martina B">B.E. Martina</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B.L. Haagmans</name></author><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T. Kuiken</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Rimmelzwaan, G F" uniqKey="Rimmelzwaan G">G.F. Rimmelzwaan</name></author><author><name sortKey="Van Amerongen, G" uniqKey="Van Amerongen G">G. Van Amerongen</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcmanus, N H" uniqKey="Mcmanus N">N.H. McManus</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcroy, W C" uniqKey="Mcroy W">W.C. McRoy</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morgenstern, B" uniqKey="Morgenstern B">B. Morgenstern</name></author><author><name sortKey="Michaelis, M" uniqKey="Michaelis M">M. Michaelis</name></author><author><name sortKey="Baer, P C" uniqKey="Baer P">P.C. Baer</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J. Cinatl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morrey, J D" uniqKey="Morrey J">J.D. Morrey</name></author><author><name sortKey="Day, C W" uniqKey="Day C">C.W. Day</name></author><author><name sortKey="Julander, J G" uniqKey="Julander J">J.G. Julander</name></author><author><name sortKey="Blatt, L M" uniqKey="Blatt L">L.M. Blatt</name></author><author><name sortKey="Smee, D F" uniqKey="Smee D">D.F. Smee</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagata, N" uniqKey="Nagata N">N. Nagata</name></author><author><name sortKey="Iwata, N" uniqKey="Iwata N">N. Iwata</name></author><author><name sortKey="Hasegawa, H" uniqKey="Hasegawa H">H. Hasegawa</name></author><author><name sortKey="Fukushi, S" uniqKey="Fukushi S">S. Fukushi</name></author><author><name sortKey="Yokoyama, M" uniqKey="Yokoyama M">M. Yokoyama</name></author><author><name sortKey="Harashima, A" uniqKey="Harashima A">A. Harashima</name></author><author><name sortKey="Sato, Y" uniqKey="Sato Y">Y. Sato</name></author><author><name sortKey="Saijo, M" uniqKey="Saijo M">M. Saijo</name></author><author><name sortKey="Morikawa, S" uniqKey="Morikawa S">S. Morikawa</name></author><author><name sortKey="Sata, T" uniqKey="Sata T">T. Sata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nagata, N" uniqKey="Nagata N">N. Nagata</name></author><author><name sortKey="Iwata, N" uniqKey="Iwata N">N. Iwata</name></author><author><name sortKey="Hasegawa, H" uniqKey="Hasegawa H">H. Hasegawa</name></author><author><name sortKey="Fukushi, S" uniqKey="Fukushi S">S. Fukushi</name></author><author><name sortKey="Harashima, A" uniqKey="Harashima A">A. Harashima</name></author><author><name sortKey="Sato, Y" uniqKey="Sato Y">Y. Sato</name></author><author><name sortKey="Saijo, M" uniqKey="Saijo M">M. Saijo</name></author><author><name sortKey="Taguchi, F" uniqKey="Taguchi F">F. Taguchi</name></author><author><name sortKey="Morikawa, S" uniqKey="Morikawa S">S. Morikawa</name></author><author><name sortKey="Sata, T" uniqKey="Sata T">T. Sata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nicholls, J M" uniqKey="Nicholls J">J.M. Nicholls</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Lee, K C" uniqKey="Lee K">K.C. Lee</name></author><author><name sortKey="Ng, W F" uniqKey="Ng W">W.F. Ng</name></author><author><name sortKey="Lai, S T" uniqKey="Lai S">S.T. Lai</name></author><author><name sortKey="Leung, C Y" uniqKey="Leung C">C.Y. Leung</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Hui, P K" uniqKey="Hui P">P.K. Hui</name></author><author><name sortKey="Mak, K L" uniqKey="Mak K">K.L. Mak</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Yan, K W" uniqKey="Yan K">K.W. Yan</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Tsang, N C" uniqKey="Tsang N">N.C. Tsang</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Niu, J" uniqKey="Niu J">J. Niu</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Dixon, R" uniqKey="Dixon R">R. Dixon</name></author><author><name sortKey="Bowden, S" uniqKey="Bowden S">S. Bowden</name></author><author><name sortKey="Qiao, M" uniqKey="Qiao M">M. Qiao</name></author><author><name sortKey="Einck, L" uniqKey="Einck L">L. Einck</name></author><author><name sortKey="Locarnini, S" uniqKey="Locarnini S">S. Locarnini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pacciarini, F" uniqKey="Pacciarini F">F. Pacciarini</name></author><author><name sortKey="Ghezzi, S" uniqKey="Ghezzi S">S. Ghezzi</name></author><author><name sortKey="Canducci, F" uniqKey="Canducci F">F. Canducci</name></author><author><name sortKey="Sims, A" uniqKey="Sims A">A. Sims</name></author><author><name sortKey="Sampaolo, M" uniqKey="Sampaolo M">M. Sampaolo</name></author><author><name sortKey="Ferioli, E" uniqKey="Ferioli E">E. Ferioli</name></author><author><name sortKey="Clementi, M" uniqKey="Clementi M">M. Clementi</name></author><author><name sortKey="Poli, G" uniqKey="Poli G">G. Poli</name></author><author><name sortKey="Conaldi, P G" uniqKey="Conaldi P">P.G. Conaldi</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author><author><name sortKey="Vicenzi, E" uniqKey="Vicenzi E">E. Vicenzi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Padalko, E" uniqKey="Padalko E">E. Padalko</name></author><author><name sortKey="Nuyens, D" uniqKey="Nuyens D">D. Nuyens</name></author><author><name sortKey="De Palma, A" uniqKey="De Palma A">A. De Palma</name></author><author><name sortKey="Verbeken, E" uniqKey="Verbeken E">E. Verbeken</name></author><author><name sortKey="Aerts, J L" uniqKey="Aerts J">J.L. Aerts</name></author><author><name sortKey="De Clercq, E" uniqKey="De Clercq E">E. De Clercq</name></author><author><name sortKey="Carmeliet, P" uniqKey="Carmeliet P">P. Carmeliet</name></author><author><name sortKey="Neyts, J" uniqKey="Neyts J">J. Neyts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, J S M" uniqKey="Peiris J">J.S.M. Peiris</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Cheng, V C C" uniqKey="Cheng V">V.C.C. Cheng</name></author><author><name sortKey="Chan, K S" uniqKey="Chan K">K.S. Chan</name></author><author><name sortKey="Hung, I F N" uniqKey="Hung I">I.F.N. Hung</name></author><author><name sortKey="Poon, L L M" uniqKey="Poon L">L.L.M. Poon</name></author><author><name sortKey="Law, K I" uniqKey="Law K">K.I. Law</name></author><author><name sortKey="Tang, B S F" uniqKey="Tang B">B.S.F. Tang</name></author><author><name sortKey="Hon, T Y W" uniqKey="Hon T">T.Y.W. Hon</name></author><author><name sortKey="Chan, C S" uniqKey="Chan C">C.S. Chan</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Ng, J S C" uniqKey="Ng J">J.S.C. Ng</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="Ng, W L" uniqKey="Ng W">W.L. Ng</name></author><author><name sortKey="Lai, R W M" uniqKey="Lai R">R.W.M. Lai</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, J S M" uniqKey="Peiris J">J.S.M. Peiris</name></author><author><name sortKey="Lai, S T" uniqKey="Lai S">S.T. Lai</name></author><author><name sortKey="Poon, L L M" uniqKey="Poon L">L.L.M. Poon</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Yam, L Y C" uniqKey="Yam L">L.Y.C. Yam</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Nicholls, J" uniqKey="Nicholls J">J. Nicholls</name></author><author><name sortKey="Yee, W K S" uniqKey="Yee W">W.K.S. Yee</name></author><author><name sortKey="Yan, W W" uniqKey="Yan W">W.W. Yan</name></author><author><name sortKey="Cheung, M T" uniqKey="Cheung M">M.T. Cheung</name></author><author><name sortKey="Cheng, V C C" uniqKey="Cheng V">V.C.C. Cheng</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Tsang, D N C" uniqKey="Tsang D">D.N.C. Tsang</name></author><author><name sortKey="Yung, R W H" uniqKey="Yung R">R.W.H. Yung</name></author><author><name sortKey="Ng, T K" uniqKey="Ng T">T.K. Ng</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Dandekar, A A" uniqKey="Dandekar A">A.A. Dandekar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pinto, A J" uniqKey="Pinto A">A.J. Pinto</name></author><author><name sortKey="Morahan, P S" uniqKey="Morahan P">P.S. Morahan</name></author><author><name sortKey="Brinton, M A" uniqKey="Brinton M">M.A. Brinton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pyrc, K" uniqKey="Pyrc K">K. Pyrc</name></author><author><name sortKey="Berkhout, B" uniqKey="Berkhout B">B. Berkhout</name></author><author><name sortKey="Van Der Hoek, L" uniqKey="Van Der Hoek L">L. van der Hoek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reed, L J" uniqKey="Reed L">L.J. Reed</name></author><author><name sortKey="Muench, M" uniqKey="Muench M">M. Muench</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roberts, A" uniqKey="Roberts A">A. Roberts</name></author><author><name sortKey="Deming, D" uniqKey="Deming D">D. Deming</name></author><author><name sortKey="Paddock, C D" uniqKey="Paddock C">C.D. Paddock</name></author><author><name sortKey="Cheng, A" uniqKey="Cheng A">A. Cheng</name></author><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Vogel, L" uniqKey="Vogel L">L. Vogel</name></author><author><name sortKey="Herman, B D" uniqKey="Herman B">B.D. Herman</name></author><author><name sortKey="Sheahan, T" uniqKey="Sheahan T">T. Sheahan</name></author><author><name sortKey="Heise, M" uniqKey="Heise M">M. Heise</name></author><author><name sortKey="Genrich, G L" uniqKey="Genrich G">G.L. Genrich</name></author><author><name sortKey="Zaki, S R" uniqKey="Zaki S">S.R. Zaki</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roberts, A" uniqKey="Roberts A">A. Roberts</name></author><author><name sortKey="Paddock, C" uniqKey="Paddock C">C. Paddock</name></author><author><name sortKey="Vogel, L" uniqKey="Vogel L">L. Vogel</name></author><author><name sortKey="Butler, E" uniqKey="Butler E">E. Butler</name></author><author><name sortKey="Zaki, S" uniqKey="Zaki S">S. Zaki</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roberts, A" uniqKey="Roberts A">A. Roberts</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roberts, A" uniqKey="Roberts A">A. Roberts</name></author><author><name sortKey="Thomas, W D" uniqKey="Thomas W">W.D. Thomas</name></author><author><name sortKey="Guarner, J" uniqKey="Guarner J">J. Guarner</name></author><author><name sortKey="Lamirande, E W" uniqKey="Lamirande E">E.W. Lamirande</name></author><author><name sortKey="Babcock, G J" uniqKey="Babcock G">G.J. Babcock</name></author><author><name sortKey="Greenough, T C" uniqKey="Greenough T">T.C. Greenough</name></author><author><name sortKey="Vogel, L" uniqKey="Vogel L">L. Vogel</name></author><author><name sortKey="Hayes, N" uniqKey="Hayes N">N. Hayes</name></author><author><name sortKey="Sullivan, J L" uniqKey="Sullivan J">J.L. Sullivan</name></author><author><name sortKey="Zaki, S" uniqKey="Zaki S">S. Zaki</name></author><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author><author><name sortKey="Ambrosino, D M" uniqKey="Ambrosino D">D.M. Ambrosino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rockx, B" uniqKey="Rockx B">B. Rockx</name></author><author><name sortKey="Sheahan, T" uniqKey="Sheahan T">T. Sheahan</name></author><author><name sortKey="Donaldson, E" uniqKey="Donaldson E">E. Donaldson</name></author><author><name sortKey="Harkema, J" uniqKey="Harkema J">J. Harkema</name></author><author><name sortKey="Sims, A" uniqKey="Sims A">A. Sims</name></author><author><name sortKey="Heise, M" uniqKey="Heise M">M. Heise</name></author><author><name sortKey="Pickles, R" uniqKey="Pickles R">R. Pickles</name></author><author><name sortKey="Cameron, M" uniqKey="Cameron M">M. Cameron</name></author><author><name sortKey="Kelvin, D" uniqKey="Kelvin D">D. Kelvin</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sadler, A J" uniqKey="Sadler A">A.J. Sadler</name></author><author><name sortKey="Williams, B R" uniqKey="Williams B">B.R. Williams</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Samuel, C E" uniqKey="Samuel C">C.E. Samuel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sheahan, T" uniqKey="Sheahan T">T. Sheahan</name></author><author><name sortKey="Rockx, B" uniqKey="Rockx B">B. Rockx</name></author><author><name sortKey="Donaldson, E" uniqKey="Donaldson E">E. Donaldson</name></author><author><name sortKey="Sims, A" uniqKey="Sims A">A. Sims</name></author><author><name sortKey="Pickles, R" uniqKey="Pickles R">R. Pickles</name></author><author><name sortKey="Corti, D" uniqKey="Corti D">D. Corti</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author><author><name sortKey="Huffman, J H" uniqKey="Huffman J">J.H. Huffman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author><author><name sortKey="Huffman, J H" uniqKey="Huffman J">J.H. Huffman</name></author><author><name sortKey="Barnard, D L" uniqKey="Barnard D">D.L. Barnard</name></author><author><name sortKey="Smee, D F" uniqKey="Smee D">D.F. Smee</name></author><author><name sortKey="Warren, R P" uniqKey="Warren R">R.P. Warren</name></author><author><name sortKey="Chirigos, M A" uniqKey="Chirigos M">M.A. Chirigos</name></author><author><name sortKey="Kende, M" uniqKey="Kende M">M. Kende</name></author><author><name sortKey="Huggins, J" uniqKey="Huggins J">J. Huggins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author><author><name sortKey="Huffman, J H" uniqKey="Huffman J">J.H. Huffman</name></author><author><name sortKey="Khare, G P" uniqKey="Khare G">G.P. Khare</name></author><author><name sortKey="Allen, L B" uniqKey="Allen L">L.B. Allen</name></author><author><name sortKey="Witkowski, J T" uniqKey="Witkowski J">J.T. Witkowski</name></author><author><name sortKey="Robins, R K" uniqKey="Robins R">R.K. Robins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smee, D F" uniqKey="Smee D">D.F. Smee</name></author><author><name sortKey="Gilbert, J" uniqKey="Gilbert J">J. Gilbert</name></author><author><name sortKey="Leonhardt, J A" uniqKey="Leonhardt J">J.A. Leonhardt</name></author><author><name sortKey="Barnett, B B" uniqKey="Barnett B">B.B. Barnett</name></author><author><name sortKey="Huggins, J H" uniqKey="Huggins J">J.H. Huggins</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smee, D F" uniqKey="Smee D">D.F. Smee</name></author><author><name sortKey="Morris, J L" uniqKey="Morris J">J.L. Morris</name></author><author><name sortKey="Leonhardt, J A" uniqKey="Leonhardt J">J.A. Leonhardt</name></author><author><name sortKey="Mead, J R" uniqKey="Mead J">J.R. Mead</name></author><author><name sortKey="Holy, A" uniqKey="Holy A">A. Holy</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stockman, L J" uniqKey="Stockman L">L.J. Stockman</name></author><author><name sortKey="Bellamy, R" uniqKey="Bellamy R">R. Bellamy</name></author><author><name sortKey="Garner, P" uniqKey="Garner P">P. Garner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Streeter, D G" uniqKey="Streeter D">D.G. Streeter</name></author><author><name sortKey="Witkowski, J T" uniqKey="Witkowski J">J.T. Witkowski</name></author><author><name sortKey="Khare, G P" uniqKey="Khare G">G.P. Khare</name></author><author><name sortKey="Sidwell, R W" uniqKey="Sidwell R">R.W. Sidwell</name></author><author><name sortKey="Bauer, R J" uniqKey="Bauer R">R.J. Bauer</name></author><author><name sortKey="Robins, R K" uniqKey="Robins R">R.K. Robins</name></author><author><name sortKey="Simon, L N" uniqKey="Simon L">L.N. Simon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stroher, U" uniqKey="Stroher U">U. Stroher</name></author><author><name sortKey="Dicaro, A" uniqKey="Dicaro A">A. DiCaro</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Strong, J E" uniqKey="Strong J">J.E. Strong</name></author><author><name sortKey="Aoki, F" uniqKey="Aoki F">F. Aoki</name></author><author><name sortKey="Plummer, F" uniqKey="Plummer F">F. Plummer</name></author><author><name sortKey="Jones, S M" uniqKey="Jones S">S.M. Jones</name></author><author><name sortKey="Feldmann, H" uniqKey="Feldmann H">H. Feldmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Subbarao, K" uniqKey="Subbarao K">K. Subbarao</name></author><author><name sortKey="Roberts, A" uniqKey="Roberts A">A. Roberts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tong, T R" uniqKey="Tong T">T.R. Tong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tong, T R" uniqKey="Tong T">T.R. Tong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Den Brand, J M" uniqKey="Van Den Brand J">J.M. van den Brand</name></author><author><name sortKey="Haagmans, B L" uniqKey="Haagmans B">B.L. Haagmans</name></author><author><name sortKey="Leijten, L" uniqKey="Leijten L">L. Leijten</name></author><author><name sortKey="Van Riel, D" uniqKey="Van Riel D">D. van Riel</name></author><author><name sortKey="Martina, B E" uniqKey="Martina B">B.E. Martina</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T. Kuiken</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Meer, F J" uniqKey="Van Der Meer F">F.J. van der Meer</name></author><author><name sortKey="De Haan, C A" uniqKey="De Haan C">C.A. de Haan</name></author><author><name sortKey="Schuurman, N M" uniqKey="Schuurman N">N.M. Schuurman</name></author><author><name sortKey="Haijema, B J" uniqKey="Haijema B">B.J. Haijema</name></author><author><name sortKey="Peumans, W J" uniqKey="Peumans W">W.J. Peumans</name></author><author><name sortKey="Van Damme, E J" uniqKey="Van Damme E">E.J. Van Damme</name></author><author><name sortKey="Delputte, P L" uniqKey="Delputte P">P.L. Delputte</name></author><author><name sortKey="Balzarini, J" uniqKey="Balzarini J">J. Balzarini</name></author><author><name sortKey="Egberink, H F" uniqKey="Egberink H">H.F. Egberink</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Meer, F J" uniqKey="Van Der Meer F">F.J. van der Meer</name></author><author><name sortKey="De Haan, C A" uniqKey="De Haan C">C.A. de Haan</name></author><author><name sortKey="Schuurman, N M" uniqKey="Schuurman N">N.M. Schuurman</name></author><author><name sortKey="Haijema, B J" uniqKey="Haijema B">B.J. Haijema</name></author><author><name sortKey="Verheije, M H" uniqKey="Verheije M">M.H. Verheije</name></author><author><name sortKey="Bosch, B J" uniqKey="Bosch B">B.J. Bosch</name></author><author><name sortKey="Balzarini, J" uniqKey="Balzarini J">J. Balzarini</name></author><author><name sortKey="Egberink, H F" uniqKey="Egberink H">H.F. Egberink</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, C H" uniqKey="Wang C">C.-H. Wang</name></author><author><name sortKey="Liu, C Y" uniqKey="Liu C">C.-Y. Liu</name></author><author><name sortKey="Wan, Y L" uniqKey="Wan Y">Y.-L. Wan</name></author><author><name sortKey="Chou, C L" uniqKey="Chou C">C.-L. Chou</name></author><author><name sortKey="Huang, K H" uniqKey="Huang K">K.-H. Huang</name></author><author><name sortKey="Lin, H C" uniqKey="Lin H">H.-C. Lin</name></author><author><name sortKey="Lin, S M" uniqKey="Lin S">S.-M. Lin</name></author><author><name sortKey="Lin, T Y" uniqKey="Lin T">T.-Y. Lin</name></author><author><name sortKey="Chung, K" uniqKey="Chung K">K. Chung</name></author><author><name sortKey="Kuo, H P" uniqKey="Kuo H">H.-P. Kuo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, W K" uniqKey="Wang W">W.-K. Wang</name></author><author><name sortKey="Chen, S Y" uniqKey="Chen S">S.-Y. Chen</name></author><author><name sortKey="Liu, I J" uniqKey="Liu I">I.J. Liu</name></author><author><name sortKey="Kao, C L" uniqKey="Kao C">C.-L. Kao</name></author><author><name sortKey="Chen, H L" uniqKey="Chen H">H.-L. Chen</name></author><author><name sortKey="Chiang, B L" uniqKey="Chiang B">B.-L. Chiang</name></author><author><name sortKey="Wang, J T" uniqKey="Wang J">J.-T. Wang</name></author><author><name sortKey="Sheng, W H" uniqKey="Sheng W">W.-H. Sheng</name></author><author><name sortKey="Hsueh, P R" uniqKey="Hsueh P">P.-R. Hsueh</name></author><author><name sortKey="Yang, C F" uniqKey="Yang C">C.-F. Yang</name></author><author><name sortKey="Yang, P C" uniqKey="Yang P">P.-C. Yang</name></author><author><name sortKey="Chang, S C" uniqKey="Chang S">S.-C. Chang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Y S" uniqKey="Wu Y">Y.S. Wu</name></author><author><name sortKey="Lin, W H" uniqKey="Lin W">W.H. Lin</name></author><author><name sortKey="Hsu, J T" uniqKey="Hsu J">J.T. Hsu</name></author><author><name sortKey="Hsieh, H P" uniqKey="Hsieh H">H.P. Hsieh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ye, J" uniqKey="Ye J">J. Ye</name></author><author><name sortKey="Zhang, B" uniqKey="Zhang B">B. Zhang</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J. Xu</name></author><author><name sortKey="Chang, Q" uniqKey="Chang Q">Q. Chang</name></author><author><name sortKey="Mcnutt, M A" uniqKey="Mcnutt M">M.A. McNutt</name></author><author><name sortKey="Korteweg, C" uniqKey="Korteweg C">C. Korteweg</name></author><author><name sortKey="Gong, E" uniqKey="Gong E">E. Gong</name></author><author><name sortKey="Gu, J" uniqKey="Gu J">J. Gu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yeung, K S" uniqKey="Yeung K">K.S. Yeung</name></author><author><name sortKey="Meanwell, N A" uniqKey="Meanwell N">N.A. Meanwell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, H Z" uniqKey="Zhang H">H.Z. Zhang</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H. Zhang</name></author><author><name sortKey="Kemnitzer, W" uniqKey="Kemnitzer W">W. Kemnitzer</name></author><author><name sortKey="Tseng, B" uniqKey="Tseng B">B. Tseng</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J. Cinatl</name></author><author><name sortKey="Michaelis, M" uniqKey="Michaelis M">M. Michaelis</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author><author><name sortKey="Cai, S X" uniqKey="Cai S">S.X. Cai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhu, M" uniqKey="Zhu M">M. Zhu</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Caroline du Nord</li><li>Utah</li></region></list><tree><country name="États-Unis"><region name="Utah"><name sortKey="Day, Craig W" sort="Day, Craig W" uniqKey="Day C" first="Craig W." last="Day">Craig W. Day</name></region><name sortKey="Baric, Ralph" sort="Baric, Ralph" uniqKey="Baric R" first="Ralph" last="Baric">Ralph Baric</name><name sortKey="Barnard, Dale L" sort="Barnard, Dale L" uniqKey="Barnard D" first="Dale L." last="Barnard">Dale L. Barnard</name><name sortKey="Cai, Sui Xiong" sort="Cai, Sui Xiong" uniqKey="Cai S" first="Sui Xiong" last="Cai">Sui Xiong Cai</name><name sortKey="Frieman, Matt" sort="Frieman, Matt" uniqKey="Frieman M" first="Matt" last="Frieman">Matt Frieman</name><name sortKey="Kumaki, Yohichi" sort="Kumaki, Yohichi" uniqKey="Kumaki Y" first="Yohichi" last="Kumaki">Yohichi Kumaki</name><name sortKey="Morrey, John D" sort="Morrey, John D" uniqKey="Morrey J" first="John D." last="Morrey">John D. Morrey</name><name sortKey="Smee, Donald F" sort="Smee, Donald F" uniqKey="Smee D" first="Donald F." last="Smee">Donald F. Smee</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002017 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 002017 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= PMC:2787736
|texte= A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:19853271" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |