Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection.
Identifieur interne : 001F00 ( Ncbi/Checkpoint ); précédent : 001E99; suivant : 001F01Lack of association between polymorphisms of MASP2 and susceptibility to SARS coronavirus infection.
Auteurs : Yan Wang [République populaire de Chine] ; Jiangwei Yan ; Yuling Shi ; Ping Li ; Chuanxuan Liu ; Qingjun Ma ; Ruifu Yang ; Xiaoyi Wang ; Lina Zhu ; Xiao Yang ; Cheng CaoSource :
- BMC infectious diseases [ 1471-2334 ] ; 2009.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Analyse de séquence d'ADN, Chine, Facteurs de risque, Femelle, Fréquence d'allèle, Génotype, Humains, Jeune adulte, Mannose-Binding Protein-Associated Serine Proteases (génétique), Mâle, Polymorphisme de nucléotide simple, Prédisposition génétique à une maladie, Syndrome respiratoire aigu sévère (génétique), Virus du SRAS, Études cas-témoins.
- MESH :
- génétique : Mannose-Binding Protein-Associated Serine Proteases, Syndrome respiratoire aigu sévère.
- Adolescent, Adulte, Adulte d'âge moyen, Analyse de séquence d'ADN, Chine, Facteurs de risque, Femelle, Fréquence d'allèle, Génotype, Humains, Jeune adulte, Mâle, Polymorphisme de nucléotide simple, Prédisposition génétique à une maladie, Virus du SRAS, Études cas-témoins.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Adolescent, Adult, Case-Control Studies, China, Female, Gene Frequency, Genetic Predisposition to Disease, Genotype, Humans, Male, Mannose-Binding Protein-Associated Serine Proteases (genetics), Middle Aged, Polymorphism, Single Nucleotide, Risk Factors, SARS Virus, Sequence Analysis, DNA, Severe Acute Respiratory Syndrome (genetics), Young Adult.
- MESH :
- chemical , genetics : Mannose-Binding Protein-Associated Serine Proteases.
- geographic : China.
- genetics : Severe Acute Respiratory Syndrome.
- Adolescent, Adult, Case-Control Studies, Female, Gene Frequency, Genetic Predisposition to Disease, Genotype, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Risk Factors, SARS Virus, Sequence Analysis, DNA, Young Adult.
Abstract
The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population.
DOI: 10.1186/1471-2334-9-51
PubMed: 19405982
Affiliations:
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pubmed:19405982Le document en format XML
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<author><name sortKey="Yang, Xiao" sort="Yang, Xiao" uniqKey="Yang X" first="Xiao" last="Yang">Xiao Yang</name>
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<author><name sortKey="Cao, Cheng" sort="Cao, Cheng" uniqKey="Cao C" first="Cheng" last="Cao">Cheng Cao</name>
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<series><title level="j">BMC infectious diseases</title>
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<term>Gene Frequency</term>
<term>Genetic Predisposition to Disease</term>
<term>Genotype</term>
<term>Humans</term>
<term>Male</term>
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<term>Chine</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Fréquence d'allèle</term>
<term>Génotype</term>
<term>Humains</term>
<term>Jeune adulte</term>
<term>Mannose-Binding Protein-Associated Serine Proteases (génétique)</term>
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<term>Études cas-témoins</term>
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<term>Genotype</term>
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<front><div type="abstract" xml:lang="en">The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population.</div>
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<name sortKey="Liu, Chuanxuan" sort="Liu, Chuanxuan" uniqKey="Liu C" first="Chuanxuan" last="Liu">Chuanxuan Liu</name>
<name sortKey="Ma, Qingjun" sort="Ma, Qingjun" uniqKey="Ma Q" first="Qingjun" last="Ma">Qingjun Ma</name>
<name sortKey="Shi, Yuling" sort="Shi, Yuling" uniqKey="Shi Y" first="Yuling" last="Shi">Yuling Shi</name>
<name sortKey="Wang, Xiaoyi" sort="Wang, Xiaoyi" uniqKey="Wang X" first="Xiaoyi" last="Wang">Xiaoyi Wang</name>
<name sortKey="Yan, Jiangwei" sort="Yan, Jiangwei" uniqKey="Yan J" first="Jiangwei" last="Yan">Jiangwei Yan</name>
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<name sortKey="Zhu, Lina" sort="Zhu, Lina" uniqKey="Zhu L" first="Lina" last="Zhu">Lina Zhu</name>
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