| Ident. | Authors (with country if any) | Title |
|---|
| 000C03 (2018) |
Dominik Dolles [Allemagne] ; Matthias Hoffmann [Allemagne] ; Sandra Gunesch [Allemagne] ; Oliviero Marinelli [Italie] ; Jan Möller [Allemagne] ; Giorgio Santoni [Italie] ; Arnaud Chatonnet [France] ; Martin J. Lohse [Allemagne] ; Hans-Joachim Wittmann [Allemagne] ; Andrea Strasser [Allemagne] ; Massimo Nabissi [Italie] ; Tangui Maurice [France] ; Michael Decker [Allemagne] | Structure–activity relationships and computational investigations into the development of potent and balanced dual-acting butyrylcholinesterase inhibitors and human cannabinoid receptor 2 ligands with pro-cognitive in vivo profiles |
| 001085 (2016) |
Thanigaimalai Pillaiyar [Allemagne] ; Manoj Manickam [Corée du Sud] ; Vigneshwaran Namasivayam [Allemagne] ; Yoshio Hayashi [Japon] ; Sang-Hun Jung [Corée du Sud] | An Overview of
Severe Acute Respiratory Syndrome–Coronavirus
(SARS-CoV) 3CL Protease Inhibitors: Peptidomimetics and Small Molecule
Chemotherapy |
| 001387 (2015) |
Sanjeev Kumar V. Vernekar [États-Unis] ; Li Qiu [États-Unis] ; Jing Zhang [États-Unis] ; Jayakanth Kankanala [États-Unis] ; Hongmin Li [États-Unis] ; Robert J. Geraghty [États-Unis] ; Zhengqiang Wang [États-Unis] | 5′-Silylated 3′-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus |
| 001808 (2013-09-26) |
Sabrina Taliani [Italie] ; Isabella Pugliesi [Italie] ; Elisabetta Barresi [Italie] ; Silvia Salerno [Italie] ; Christophe Marchand [États-Unis] ; Keli Agama [États-Unis] ; Francesca Simorini [Italie] ; Concettina La Motta [Italie] ; Anna Maria Marini [Italie] ; Francesco Saverio Di Leva ; Luciana Marinelli ; Sandro Cosconati [Italie] ; Ettore Novellino [Italie] ; Yves Pommier [France] ; Roberto Di Santo [Italie] ; Federico Da Settimo [Italie] | Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin topoisomerase I (Top1) inhibitors. |
| 002483 (2010) |
Arun K. Ghosh [États-Unis] ; Jun Takayama [États-Unis] ; Kalapala Venkateswara Rao [États-Unis] ; Kiira Ratia [États-Unis] ; Rima Chaudhuri [États-Unis] ; Debbie C. Mulhearn [États-Unis] ; Hyun Lee [États-Unis] ; Daniel B. Nichols [États-Unis] ; Surendranath Baliji [États-Unis] ; Susan C. Baker [États-Unis] ; Michael E. Johnson [États-Unis] ; Andrew D. Mesecar [États-Unis] | Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Novel Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation |
| 002A52 (2009) |
Arun K. Ghosh [États-Unis] ; Jun Takayama [États-Unis] ; Yoann Aubin [États-Unis] ; Kiira Ratia [États-Unis] ; Rima Chaudhuri [États-Unis] ; Yahira Baez [États-Unis] ; Katrina Sleeman [États-Unis] ; Melissa Coughlin [États-Unis] ; Daniel B. Nichols [États-Unis] ; Debbie C. Mulhearn [États-Unis] ; Bellur S. Prabhakar [États-Unis] ; Susan C. Baker [États-Unis] ; Michael E. Johnson [États-Unis] ; Andrew D. Mesecar [États-Unis] | Structure-Based Design, Synthesis, and Biological Evaluation of a Series of Novel and Reversible Inhibitors for the Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Protease |
| 002F60 (2009) |
Arun K. Ghosh [États-Unis] ; Jun Takayama [États-Unis] ; Yoann Aubin [États-Unis] ; Kiira Ratia [États-Unis] ; Rima Chaudhuri [États-Unis] ; Yahira Baez [États-Unis] ; Katrina Sleeman [États-Unis] ; Melissa Coughlin [États-Unis] ; Daniel B. Nichols [États-Unis] ; Debbie C. Mulhearn [États-Unis] ; Bellur S. Prabhakar [États-Unis] ; Susan C. Bakery [États-Unis] ; Michael E. Johnson [États-Unis] ; Andrew D. Mesecar [États-Unis] | Structure-Based Design, Synthesis, and Biological Evaluation of a Series of Novel and Reversible Inhibitors for the Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Protease |
| 003243 (2008) |
Tao Ma [République populaire de Chine] ; Li Liu ; Hai Xue ; Li Li ; Chunyan Han ; Lin Wang ; Zhiwei Chen ; Gang Liu | Chemical library and structure-activity relationships of 11-demethyl-12-oxo calanolide A analogues as anti-HIV-1 agents. |
| 003621 (2008) |
TAO MA [République populaire de Chine] ; LI LIU [Hong Kong] ; HAI XUE [République populaire de Chine] ; LI LI [République populaire de Chine] ; CHUNYAN HAN [République populaire de Chine] ; LIN WANG [République populaire de Chine] ; ZHIWEI CHEN [Hong Kong] ; GANG LIU [République populaire de Chine] | Chemical Library and Structure-Activity Relationships of 11-Demethyl-12-oxo Calanolide A Analogues as Anti-HIV-1 Agents |
| 003708 (2007) |
Chih-Chun Wen [République populaire de Chine] ; Yueh-Hsiung Kuo ; Jia-Tsrong Jan ; Po-Huang Liang ; Sheng-Yang Wang ; Hong-Gi Liu ; Ching-Kuo Lee ; Shang-Tzen Chang ; Chih-Jung Kuo ; Shoei-Sheng Lee ; Chia-Chung Hou ; Pei-Wen Hsiao ; Shih-Chang Chien ; Lie-Fen Shyur ; Ning-Sun Yang | Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus. |
| 003965 (2007) |
Igor A. Schepetkin [Russie] ; Andrei I. Khlebnikov [Russie] ; Mark T. Quinn [Russie, États-Unis] | N-Benzoylpyrazoles Are Novel Small-Molecule Inhibitors of Human Neutrophil Elastase |
| 003C78 (2007) |
Chih-Chun Wen [Taïwan] ; Yueh-Hsiung Kuo [Taïwan] ; Jia-Tsrong Jan [Taïwan] ; Po-Huang Liang [Taïwan] ; Sheng-Yang Wang [Taïwan] ; Hong-Gi Liu [Taïwan] ; Ching-Kuo Lee [Taïwan] ; Shang-Tzen Chang [Taïwan] ; Chih-Jung Kuo [Taïwan] ; Shoei-Sheng Lee [Taïwan] ; Chia-Chung Hou [Taïwan] ; Pei-Wen Hsiao [Taïwan] ; Shih-Chang Chien [Taïwan] ; Lie-Fen Shyur [Taïwan] ; Ning-Sun Yang [Taïwan] | Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus |
| 003D37 (2007) |
JIANMIN ZHANG [Canada] ; Hanna I. Pettersson [Canada] ; Carly Huitema [Canada] ; CHUNYING NIU [Canada] ; JIANG YIN [Canada] ; Michael N. G. James [Canada] ; Lindsay D. Eltis [Canada] ; John C. Vederas [Canada] | Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters |
| 003E43 (2006) |
Syaulan Yang [République populaire de Chine] ; Shu-Jen Chen ; Min-Feng Hsu ; Jen-Dar Wu ; Chien-Te K. Tseng ; Yu-Fan Liu ; Hua-Chien Chen ; Chun-Wei Kuo ; Chi-Shen Wu ; Li-Wen Chang ; Wen-Chang Chen ; Shao-Ying Liao ; Teng-Yuan Chang ; Hsin-Hui Hung ; Hui-Lin Shr ; Cheng-Yuan Liu ; Yu-An Huang ; Ling-Yin Chang ; Jen-Chi Hsu ; Clarence J. Peters ; Andrew H-J Wang ; Ming-Chu Hsu | Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor. |
| 003E45 (2006) |
Jong Hyun Cho [États-Unis] ; Dale L. Bernard ; Robert W. Sidwell ; Earl R. Kern ; Chung K. Chu | Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS. |
| 003F78 (2006) |
Roberto Di Santo [Italie] ; Roberta Costi ; Alessandra Roux ; Marino Artico ; Antonio Lavecchia ; Luciana Marinelli ; Ettore Novellino ; Lucia Palmisano ; Mauro Andreotti ; Roberta Amici ; Clementina Maria Galluzzo ; Lucia Nencioni ; Anna Teresa Palamara ; Yves Pommier ; Christophe Marchand | Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action. |
| 004019 (2006) |
Lu Zhou [République populaire de Chine] ; Ying Liu ; Weilin Zhang ; Ping Wei ; Changkang Huang ; Jianfeng Pei ; Yaxia Yuan ; Luhua Lai | Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors. |
| 004128 (2006) |
Han-Zhong Zhang [États-Unis] ; Hong Zhang ; William Kemnitzer ; Ben Tseng ; Jindrich Cinatl ; Martin Michaelis ; Hans Wilhelm Doerr ; Sui Xiong Cai | Design and synthesis of dipeptidyl glutaminyl fluoromethyl ketones as potent severe acute respiratory syndrome coronovirus (SARS-CoV) inhibitors. |
| 004186 (2006) |
Christopher Mcguigan [Royaume-Uni] ; Alshaimaa Hassan-Abdallah ; Sheila Srinivasan ; Yikang Wang ; Adam Siddiqui ; Susan M. Daluge ; Kristjan S. Gudmundsson ; Huiqiang Zhou ; Ed W. Mclean ; Jennifer P. Peckham ; Thimysta C. Burnette ; Harry Marr ; Richard Hazen ; Lynn D. Condreay ; Lance Johnson ; Jan Balzarini | Application of phosphoramidate ProTide technology significantly improves antiviral potency of carbocyclic adenosine derivatives. |
| 004257 (2006) |
I-Lin Lu [République populaire de Chine] ; Neeraj Mahindroo [République populaire de Chine] ; Po-Huang Liang [République populaire de Chine] ; Yi-Hui Peng [République populaire de Chine] ; Chih-Jung Kuo [République populaire de Chine] ; Keng-Chang Tsai [République populaire de Chine] ; Hsing-Pang Hsieh [République populaire de Chine] ; Yu-Sheng Chao [République populaire de Chine] ; Su-Ying Wu [République populaire de Chine, Taïwan] | Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Main Protease |
| 004274 (2006) |
Igor A. Schepetkin [Russie] ; Andrei I. Khlebnikov [Russie] ; Liliya N. Kirpotina [Russie] ; Mark T. Quinn [Russie, États-Unis] | Novel Small-Molecule Inhibitors of Anthrax Lethal Factor Identified by High-Throughput Screening |
