Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China
Identifieur interne : 004D15 ( Main/Merge ); précédent : 004D14; suivant : 004D16Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China
Auteurs : Susan S. Chiu [République populaire de Chine] ; Kwok Hung Chan [République populaire de Chine] ; Ka Wing Chu [République populaire de Chine] ; See Wai Kwan [République populaire de Chine] ; Yi Guan [République populaire de Chine] ; Leo Lit Man Poon [République populaire de Chine] ; J. S. M. Peiris [République populaire de Chine, Hong Kong]Source :
- Clinical Infectious Diseases [ 1058-4838 ] ; 2005.
Descripteurs français
- KwdFr :
- Adolescent, Coronavirus (), Coronavirus (isolement et purification), Enfant, Enfant d'âge préscolaire, Hong Kong (épidémiologie), Hospitalisation, Humains, Infections de l'appareil respiratoire (diagnostic), Infections de l'appareil respiratoire (virologie), Infections de l'appareil respiratoire (épidémiologie), Infections à coronavirus (diagnostic), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Nourrisson, Saisons.
- MESH :
- diagnostic : Infections de l'appareil respiratoire, Infections à coronavirus.
- isolement et purification : Coronavirus.
- virologie : Infections de l'appareil respiratoire, Infections à coronavirus.
- épidémiologie : Hong Kong, Infections de l'appareil respiratoire, Infections à coronavirus.
- Adolescent, Coronavirus, Enfant, Enfant d'âge préscolaire, Hospitalisation, Humains, Nourrisson, Saisons.
- Wicri :
- geographic : Hong Kong.
English descriptors
- KwdEn :
- Adolescent, Child, Child, Preschool, Coronavirus (classification), Coronavirus (isolation & purification), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Coronavirus Infections (virology), Hong Kong (epidemiology), Hospitalization, Humans, Infant, Respiratory Tract Infections (diagnosis), Respiratory Tract Infections (epidemiology), Respiratory Tract Infections (virology), Seasons.
- MESH :
- geographic , epidemiology : Hong Kong.
- classification : Coronavirus.
- diagnosis : Coronavirus Infections, Respiratory Tract Infections.
- epidemiology : Coronavirus Infections, Respiratory Tract Infections.
- isolation & purification : Coronavirus.
- virology : Coronavirus Infections, Respiratory Tract Infections.
- Adolescent, Child, Child, Preschool, Hospitalization, Humans, Infant, Seasons.
Abstract
Background. Human coronavirus NL63 (HCoV-NL63) is a recently discovered human coronavirus found to cause respiratory illness in children and adults that is distinct from the severe acute respiratory syndrome (SARS) coronavirus and human coronaviruses 229E (HCoV-229E) and OC43 (HCoV-OC43). Methods. We investigated the role that HCoV-NL63, HCoV-OC43, and HCoV-229E played in children hospitalized with fever and acute respiratory symptoms in Hong Kong during the period from August 2001 through August 2002. Results. Coronavirus infections were detected in 26 (4.4%) of 587 children studied; 15 (2.6%) were positive for HCoV-NL63, 9 (1.5%) were positive for HCoV-OC43, and 2 (0.3%) were positive for HCoV-229E. In addition to causing upper respiratory disease, we found that HCoV-NL63 can present as croup, asthma exacerbation, febrile seizures, and high fever. The mean age (± standard deviation [SD]) of the infected children was 30.7 ± 19.8 months (range, 6–57 months). The mean maximum temperature (±SD) for the 12 children who were febrile was 39.3°C ± 0.9°C, and the mean total duration of fever (±SD) for all children was 2.6 ± 1.2 days (range, 1–5 days). HCoV-NL63 infections were noted in the spring and summer months of 2002, whereas HCoV-OC43 infection mainly occurred in the fall and winter months of 2001. HCoV-NL63 viruses appeared to cluster into 2 evolutionary lineages, and viruses from both lineages cocirculated in the same season. Conclusions. HCoV-NL63 is a significant pathogen that contributes to the hospitalization of children, and it was estimated to have caused 224 hospital admissions per 100,000 population aged ⩽6 years each year in Hong Kong.
Url:
DOI: 10.1086/430301
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Chiu</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Paediatrics and Adolescent Medicine</wicri:regionArea></affiliation></author><author><name sortKey="Hung Chan, Kwok" sort="Hung Chan, Kwok" uniqKey="Hung Chan K" first="Kwok" last="Hung Chan">Kwok Hung Chan</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Wing Chu, Ka" sort="Wing Chu, Ka" uniqKey="Wing Chu K" first="Ka" last="Wing Chu">Ka Wing Chu</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Kwan, See Wai" sort="Kwan, See Wai" uniqKey="Kwan S" first="See Wai" last="Kwan">See Wai Kwan</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Guan, Yi" sort="Guan, Yi" uniqKey="Guan Y" first="Yi" last="Guan">Yi Guan</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Man Poon, Leo Lit" sort="Man Poon, Leo Lit" uniqKey="Man Poon L" first="Leo Lit" last="Man Poon">Leo Lit Man Poon</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J. S. M." last="Peiris">J. S. M. Peiris</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Hong Kong</country></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Hong Kong</country><wicri:regionArea>Reprints or correspondence: Dr. J. S. M. 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Human coronavirus NL63 (HCoV-NL63) is a recently discovered human coronavirus found to cause respiratory illness in children and adults that is distinct from the severe acute respiratory syndrome (SARS) coronavirus and human coronaviruses 229E (HCoV-229E) and OC43 (HCoV-OC43). Methods. We investigated the role that HCoV-NL63, HCoV-OC43, and HCoV-229E played in children hospitalized with fever and acute respiratory symptoms in Hong Kong during the period from August 2001 through August 2002. Results. Coronavirus infections were detected in 26 (4.4%) of 587 children studied; 15 (2.6%) were positive for HCoV-NL63, 9 (1.5%) were positive for HCoV-OC43, and 2 (0.3%) were positive for HCoV-229E. In addition to causing upper respiratory disease, we found that HCoV-NL63 can present as croup, asthma exacerbation, febrile seizures, and high fever. The mean age (± standard deviation [SD]) of the infected children was 30.7 ± 19.8 months (range, 6–57 months). The mean maximum temperature (±SD) for the 12 children who were febrile was 39.3°C ± 0.9°C, and the mean total duration of fever (±SD) for all children was 2.6 ± 1.2 days (range, 1–5 days). HCoV-NL63 infections were noted in the spring and summer months of 2002, whereas HCoV-OC43 infection mainly occurred in the fall and winter months of 2001. HCoV-NL63 viruses appeared to cluster into 2 evolutionary lineages, and viruses from both lineages cocirculated in the same season. Conclusions. HCoV-NL63 is a significant pathogen that contributes to the hospitalization of children, and it was estimated to have caused 224 hospital admissions per 100,000 population aged ⩽6 years each year in Hong Kong.</div></front></TEI><double doi="10.1086/430301"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China</title><author><name sortKey="Chiu, Susan S" sort="Chiu, Susan S" uniqKey="Chiu S" first="Susan S." last="Chiu">Susan S. Chiu</name></author><author><name sortKey="Hung Chan, Kwok" sort="Hung Chan, Kwok" uniqKey="Hung Chan K" first="Kwok" last="Hung Chan">Kwok Hung Chan</name></author><author><name sortKey="Wing Chu, Ka" sort="Wing Chu, Ka" uniqKey="Wing Chu K" first="Ka" last="Wing Chu">Ka Wing Chu</name></author><author><name sortKey="Kwan, See Wai" sort="Kwan, See Wai" uniqKey="Kwan S" first="See Wai" last="Kwan">See Wai Kwan</name></author><author><name sortKey="Guan, Yi" sort="Guan, Yi" uniqKey="Guan Y" first="Yi" last="Guan">Yi Guan</name></author><author><name sortKey="Man Poon, Leo Lit" sort="Man Poon, Leo Lit" uniqKey="Man Poon L" first="Leo Lit" last="Man Poon">Leo Lit Man Poon</name></author><author><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J. S. M." last="Peiris">J. S. M. Peiris</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1B6A2802D03B86FA7217260054DBA4B1C438D974</idno><date when="2005" year="2005">2005</date><idno type="doi">10.1086/430301</idno><idno type="url">https://api.istex.fr/ark:/67375/HXZ-WRBZMT2X-V/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000618</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000618</idno><idno type="wicri:Area/Istex/Curation">000618</idno><idno type="wicri:Area/Istex/Checkpoint">001848</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001848</idno><idno type="wicri:doubleKey">1058-4838:2005:Chiu S:human:coronavirus:nl</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China</title><author><name sortKey="Chiu, Susan S" sort="Chiu, Susan S" uniqKey="Chiu S" first="Susan S." last="Chiu">Susan S. Chiu</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Paediatrics and Adolescent Medicine</wicri:regionArea></affiliation></author><author><name sortKey="Hung Chan, Kwok" sort="Hung Chan, Kwok" uniqKey="Hung Chan K" first="Kwok" last="Hung Chan">Kwok Hung Chan</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Wing Chu, Ka" sort="Wing Chu, Ka" uniqKey="Wing Chu K" first="Ka" last="Wing Chu">Ka Wing Chu</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Kwan, See Wai" sort="Kwan, See Wai" uniqKey="Kwan S" first="See Wai" last="Kwan">See Wai Kwan</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Guan, Yi" sort="Guan, Yi" uniqKey="Guan Y" first="Yi" last="Guan">Yi Guan</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Man Poon, Leo Lit" sort="Man Poon, Leo Lit" uniqKey="Man Poon L" first="Leo Lit" last="Man Poon">Leo Lit Man Poon</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation></author><author><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J. S. M." last="Peiris">J. S. M. Peiris</name><affiliation wicri:level="1"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea><wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Hong Kong</country></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Hong Kong</country><wicri:regionArea>Reprints or correspondence: Dr. J. S. M. Peiris, Dept. of Microbiology, The University Pathology Building, Queen Mary Hospital, 102 Pokfulam Rd., Pokfulam, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Clinical Infectious Diseases</title><title level="j" type="abbrev">Clinical Infectious Diseases</title><idno type="ISSN">1058-4838</idno><idno type="eISSN">1537-6591</idno><imprint><publisher>The University of Chicago Press</publisher><date type="published">2005</date><biblScope unit="vol">40</biblScope><biblScope unit="issue">12</biblScope><biblScope unit="page" from="1721">1721</biblScope><biblScope unit="page" to="1729">1729</biblScope></imprint><idno type="ISSN">1058-4838</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1058-4838</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Background. Human coronavirus NL63 (HCoV-NL63) is a recently discovered human coronavirus found to cause respiratory illness in children and adults that is distinct from the severe acute respiratory syndrome (SARS) coronavirus and human coronaviruses 229E (HCoV-229E) and OC43 (HCoV-OC43). Methods. We investigated the role that HCoV-NL63, HCoV-OC43, and HCoV-229E played in children hospitalized with fever and acute respiratory symptoms in Hong Kong during the period from August 2001 through August 2002. Results. Coronavirus infections were detected in 26 (4.4%) of 587 children studied; 15 (2.6%) were positive for HCoV-NL63, 9 (1.5%) were positive for HCoV-OC43, and 2 (0.3%) were positive for HCoV-229E. In addition to causing upper respiratory disease, we found that HCoV-NL63 can present as croup, asthma exacerbation, febrile seizures, and high fever. The mean age (± standard deviation [SD]) of the infected children was 30.7 ± 19.8 months (range, 6–57 months). The mean maximum temperature (±SD) for the 12 children who were febrile was 39.3°C ± 0.9°C, and the mean total duration of fever (±SD) for all children was 2.6 ± 1.2 days (range, 1–5 days). HCoV-NL63 infections were noted in the spring and summer months of 2002, whereas HCoV-OC43 infection mainly occurred in the fall and winter months of 2001. HCoV-NL63 viruses appeared to cluster into 2 evolutionary lineages, and viruses from both lineages cocirculated in the same season. Conclusions. HCoV-NL63 is a significant pathogen that contributes to the hospitalization of children, and it was estimated to have caused 224 hospital admissions per 100,000 population aged ⩽6 years each year in Hong Kong.</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China.</title><author><name sortKey="Chiu, Susan S" sort="Chiu, Susan S" uniqKey="Chiu S" first="Susan S" last="Chiu">Susan S. Chiu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Chan, Kwok Hung" sort="Chan, Kwok Hung" uniqKey="Chan K" first="Kwok Hung" last="Chan">Kwok Hung Chan</name></author><author><name sortKey="Chu, Ka Wing" sort="Chu, Ka Wing" uniqKey="Chu K" first="Ka Wing" last="Chu">Ka Wing Chu</name></author><author><name sortKey="Kwan, See Wai" sort="Kwan, See Wai" uniqKey="Kwan S" first="See Wai" last="Kwan">See Wai Kwan</name></author><author><name sortKey="Guan, Yi" sort="Guan, Yi" uniqKey="Guan Y" first="Yi" last="Guan">Yi Guan</name></author><author><name sortKey="Poon, Leo Lit Man" sort="Poon, Leo Lit Man" uniqKey="Poon L" first="Leo Lit Man" last="Poon">Leo Lit Man Poon</name></author><author><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J S M" last="Peiris">J S M. Peiris</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2005">2005</date><idno type="RBID">pubmed:15909257</idno><idno type="pmid">15909257</idno><idno type="doi">10.1086/430301</idno><idno type="wicri:Area/PubMed/Corpus">002724</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002724</idno><idno type="wicri:Area/PubMed/Curation">002724</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002724</idno><idno type="wicri:Area/PubMed/Checkpoint">002684</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002684</idno><idno type="wicri:Area/Ncbi/Merge">000F65</idno><idno type="wicri:Area/Ncbi/Curation">000F65</idno><idno type="wicri:Area/Ncbi/Checkpoint">000F65</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, China.</title><author><name sortKey="Chiu, Susan S" sort="Chiu, Susan S" uniqKey="Chiu S" first="Susan S" last="Chiu">Susan S. Chiu</name><affiliation wicri:level="1"><nlm:affiliation>Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong</wicri:regionArea><wicri:noRegion>Hong Kong</wicri:noRegion></affiliation></author><author><name sortKey="Chan, Kwok Hung" sort="Chan, Kwok Hung" uniqKey="Chan K" first="Kwok Hung" last="Chan">Kwok Hung Chan</name></author><author><name sortKey="Chu, Ka Wing" sort="Chu, Ka Wing" uniqKey="Chu K" first="Ka Wing" last="Chu">Ka Wing Chu</name></author><author><name sortKey="Kwan, See Wai" sort="Kwan, See Wai" uniqKey="Kwan S" first="See Wai" last="Kwan">See Wai Kwan</name></author><author><name sortKey="Guan, Yi" sort="Guan, Yi" uniqKey="Guan Y" first="Yi" last="Guan">Yi Guan</name></author><author><name sortKey="Poon, Leo Lit Man" sort="Poon, Leo Lit Man" uniqKey="Poon L" first="Leo Lit Man" last="Poon">Leo Lit Man Poon</name></author><author><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J S M" last="Peiris">J S M. Peiris</name></author></analytic><series><title level="j">Clinical infectious diseases : an official publication of the Infectious Diseases Society of America</title><idno type="eISSN">1537-6591</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Child</term><term>Child, Preschool</term><term>Coronavirus (classification)</term><term>Coronavirus (isolation & purification)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (virology)</term><term>Hong Kong (epidemiology)</term><term>Hospitalization</term><term>Humans</term><term>Infant</term><term>Respiratory Tract Infections (diagnosis)</term><term>Respiratory Tract Infections (epidemiology)</term><term>Respiratory Tract Infections (virology)</term><term>Seasons</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Coronavirus ()</term><term>Coronavirus (isolement et purification)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Hong Kong (épidémiologie)</term><term>Hospitalisation</term><term>Humains</term><term>Infections de l'appareil respiratoire (diagnostic)</term><term>Infections de l'appareil respiratoire (virologie)</term><term>Infections de l'appareil respiratoire (épidémiologie)</term><term>Infections à coronavirus (diagnostic)</term><term>Infections à coronavirus (virologie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Nourrisson</term><term>Saisons</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Hong Kong</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections de l'appareil respiratoire</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections de l'appareil respiratoire</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Hong Kong</term><term>Infections de l'appareil respiratoire</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Child</term><term>Child, Preschool</term><term>Hospitalization</term><term>Humans</term><term>Infant</term><term>Seasons</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Coronavirus</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Hospitalisation</term><term>Humains</term><term>Nourrisson</term><term>Saisons</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Hong Kong</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Human coronavirus NL63 (HCoV-NL63) is a recently discovered human coronavirus found to cause respiratory illness in children and adults that is distinct from the severe acute respiratory syndrome (SARS) coronavirus and human coronaviruses 229E (HCoV-229E) and OC43 (HCoV-OC43).</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
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