Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats
Identifieur interne : 004888 ( Main/Merge ); précédent : 004887; suivant : 004889Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats
Auteurs : Susanna K. P. Lau ; Patrick C. Y. Woo ; Kenneth S. M. Li ; Yi Huang ; Hoi-Wah Tsoi ; Beatrice H. L. Wong ; Samson S. Y. Wong ; Suet-Yi Leung [République populaire de Chine] ; Kwok-Hung Chan ; Kwok-Yung YuenSource :
- Proceedings of the National Academy of Sciences of the United States of America [ 0027-8424 ] ; 2005.
Descripteurs français
- KwdFr :
- Analyse de séquence d'ADN, Animaux, Chiroptera (virologie), Données de séquences moléculaires, Génome viral, Hong Kong, Phylogénie, Protéines virales (génétique), Protéines virales (sang), Séquence d'acides aminés, Séquence nucléotidique, Virus du SRAS (), Virus du SRAS (génétique), Virus du SRAS (isolement et purification).
- MESH :
- génétique : Protéines virales, Virus du SRAS.
- isolement et purification : Virus du SRAS.
- sang : Protéines virales.
- virologie : Chiroptera.
- Analyse de séquence d'ADN, Animaux, Données de séquences moléculaires, Génome viral, Hong Kong, Phylogénie, Séquence d'acides aminés, Séquence nucléotidique, Virus du SRAS.
- Wicri :
- geographic : Hong Kong.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Viral Proteins.
- chemical , genetics : Viral Proteins.
- geographic : Hong Kong.
- classification : SARS Virus.
- genetics : SARS Virus.
- isolation & purification : SARS Virus.
- virology : Chiroptera.
- Amino Acid Sequence, Animals, Base Sequence, Genome, Viral, Molecular Sequence Data, Phylogeny, Sequence Analysis, DNA.
Abstract
Although the finding of severe acute respiratory syndrome coronavirus (SARS-CoV) in caged palm civets from live animal markets in China has provided evidence for interspecies transmission in the genesis of the SARS epidemic, subsequent studies suggested that the civet may have served only as an amplification host for SARS-CoV. In a surveillance study for CoV in noncaged animals from the wild areas of the Hong Kong Special Administration Region, we identified a CoV closely related to SARS-CoV (bat-SARS-CoV) from 23 (39%) of 59 anal swabs of wild Chinese horseshoe bats (
Url:
DOI: 10.1073/pnas.0506735102
PubMed: 16169905
PubMed Central: 1236580
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000746
- to stream Pmc, to step Curation: 000746
- to stream Pmc, to step Checkpoint: 001227
- to stream PubMed, to step Corpus: 002538
- to stream PubMed, to step Curation: 002538
- to stream PubMed, to step Checkpoint: 002483
- to stream Ncbi, to step Merge: 001165
- to stream Ncbi, to step Curation: 001165
- to stream Ncbi, to step Checkpoint: 001165
Links to Exploration step
PMC:1236580Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats</title>
<author><name sortKey="Lau, Susanna K P" sort="Lau, Susanna K P" uniqKey="Lau S" first="Susanna K. P." last="Lau">Susanna K. P. Lau</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Research Centre of Infection and Immunology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="N0x9b35768.0x9ac1b40">State Key Laboratory of Emerging Infectious Diseases</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Woo, Patrick C Y" sort="Woo, Patrick C Y" uniqKey="Woo P" first="Patrick C. Y." last="Woo">Patrick C. Y. Woo</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Research Centre of Infection and Immunology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="N0x9b35768.0x9ac1b40">State Key Laboratory of Emerging Infectious Diseases</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Li, Kenneth S M" sort="Li, Kenneth S M" uniqKey="Li K" first="Kenneth S. M." last="Li">Kenneth S. M. Li</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Huang, Yi" sort="Huang, Yi" uniqKey="Huang Y" first="Yi" last="Huang">Yi Huang</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tsoi, Hoi Wah" sort="Tsoi, Hoi Wah" uniqKey="Tsoi H" first="Hoi-Wah" last="Tsoi">Hoi-Wah Tsoi</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wong, Beatrice H L" sort="Wong, Beatrice H L" uniqKey="Wong B" first="Beatrice H. L." last="Wong">Beatrice H. L. Wong</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wong, Samson S Y" sort="Wong, Samson S Y" uniqKey="Wong S" first="Samson S. Y." last="Wong">Samson S. Y. Wong</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Research Centre of Infection and Immunology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="N0x9b35768.0x9ac1b40">State Key Laboratory of Emerging Infectious Diseases</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Leung, Suet Yi" sort="Leung, Suet Yi" uniqKey="Leung S" first="Suet-Yi" last="Leung">Suet-Yi Leung</name>
<affiliation wicri:level="1"><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Pathology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pathology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region</wicri:regionArea>
<wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chan, Kwok Hung" sort="Chan, Kwok Hung" uniqKey="Chan K" first="Kwok-Hung" last="Chan">Kwok-Hung Chan</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Research Centre of Infection and Immunology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="N0x9b35768.0x9ac1b40">State Key Laboratory of Emerging Infectious Diseases</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">16169905</idno>
<idno type="pmc">1236580</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236580</idno>
<idno type="RBID">PMC:1236580</idno>
<idno type="doi">10.1073/pnas.0506735102</idno>
<date when="2005">2005</date>
<idno type="wicri:Area/Pmc/Corpus">000746</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000746</idno>
<idno type="wicri:Area/Pmc/Curation">000746</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000746</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001227</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001227</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:16169905</idno>
<idno type="wicri:Area/PubMed/Corpus">002538</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002538</idno>
<idno type="wicri:Area/PubMed/Curation">002538</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002538</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002483</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002483</idno>
<idno type="wicri:Area/Ncbi/Merge">001165</idno>
<idno type="wicri:Area/Ncbi/Curation">001165</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001165</idno>
<idno type="wicri:doubleKey">0027-8424:2005:Lau S:severe:acute:respiratory</idno>
<idno type="wicri:Area/Main/Merge">004888</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats</title>
<author><name sortKey="Lau, Susanna K P" sort="Lau, Susanna K P" uniqKey="Lau S" first="Susanna K. P." last="Lau">Susanna K. P. Lau</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Research Centre of Infection and Immunology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="N0x9b35768.0x9ac1b40">State Key Laboratory of Emerging Infectious Diseases</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Woo, Patrick C Y" sort="Woo, Patrick C Y" uniqKey="Woo P" first="Patrick C. Y." last="Woo">Patrick C. Y. Woo</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Research Centre of Infection and Immunology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="N0x9b35768.0x9ac1b40">State Key Laboratory of Emerging Infectious Diseases</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Li, Kenneth S M" sort="Li, Kenneth S M" uniqKey="Li K" first="Kenneth S. M." last="Li">Kenneth S. M. Li</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Huang, Yi" sort="Huang, Yi" uniqKey="Huang Y" first="Yi" last="Huang">Yi Huang</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tsoi, Hoi Wah" sort="Tsoi, Hoi Wah" uniqKey="Tsoi H" first="Hoi-Wah" last="Tsoi">Hoi-Wah Tsoi</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wong, Beatrice H L" sort="Wong, Beatrice H L" uniqKey="Wong B" first="Beatrice H. L." last="Wong">Beatrice H. L. Wong</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Wong, Samson S Y" sort="Wong, Samson S Y" uniqKey="Wong S" first="Samson S. Y." last="Wong">Samson S. Y. Wong</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Research Centre of Infection and Immunology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="N0x9b35768.0x9ac1b40">State Key Laboratory of Emerging Infectious Diseases</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Leung, Suet Yi" sort="Leung, Suet Yi" uniqKey="Leung S" first="Suet-Yi" last="Leung">Suet-Yi Leung</name>
<affiliation wicri:level="1"><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Pathology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China</nlm:aff>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Pathology, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region</wicri:regionArea>
<wicri:noRegion>Hong Kong Special Administrative Region</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chan, Kwok Hung" sort="Chan, Kwok Hung" uniqKey="Chan K" first="Kwok-Hung" last="Chan">Kwok-Hung Chan</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Department of Microbiology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="N0x9b35768.0x9ac1b40">Research Centre of Infection and Immunology,</nlm:aff>
</affiliation>
<affiliation><nlm:aff wicri:cut=", and" id="N0x9b35768.0x9ac1b40">State Key Laboratory of Emerging Infectious Diseases</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Proceedings of the National Academy of Sciences of the United States of America</title>
<idno type="ISSN">0027-8424</idno>
<idno type="eISSN">1091-6490</idno>
<imprint><date when="2005">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino Acid Sequence</term>
<term>Animals</term>
<term>Base Sequence</term>
<term>Chiroptera (virology)</term>
<term>Genome, Viral</term>
<term>Hong Kong</term>
<term>Molecular Sequence Data</term>
<term>Phylogeny</term>
<term>SARS Virus (classification)</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (isolation & purification)</term>
<term>Sequence Analysis, DNA</term>
<term>Viral Proteins (blood)</term>
<term>Viral Proteins (genetics)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Analyse de séquence d'ADN</term>
<term>Animaux</term>
<term>Chiroptera (virologie)</term>
<term>Données de séquences moléculaires</term>
<term>Génome viral</term>
<term>Hong Kong</term>
<term>Phylogénie</term>
<term>Protéines virales (génétique)</term>
<term>Protéines virales (sang)</term>
<term>Séquence d'acides aminés</term>
<term>Séquence nucléotidique</term>
<term>Virus du SRAS ()</term>
<term>Virus du SRAS (génétique)</term>
<term>Virus du SRAS (isolement et purification)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Viral Proteins</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Hong Kong</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines virales</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Protéines virales</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Chiroptera</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Chiroptera</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term>
<term>Animals</term>
<term>Base Sequence</term>
<term>Genome, Viral</term>
<term>Molecular Sequence Data</term>
<term>Phylogeny</term>
<term>Sequence Analysis, DNA</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Analyse de séquence d'ADN</term>
<term>Animaux</term>
<term>Données de séquences moléculaires</term>
<term>Génome viral</term>
<term>Hong Kong</term>
<term>Phylogénie</term>
<term>Séquence d'acides aminés</term>
<term>Séquence nucléotidique</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Hong Kong</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>Although the finding of severe acute respiratory syndrome coronavirus (SARS-CoV) in caged palm civets from live animal markets in China has provided evidence for interspecies transmission in the genesis of the SARS epidemic, subsequent studies suggested that the civet may have served only as an amplification host for SARS-CoV. In a surveillance study for CoV in noncaged animals from the wild areas of the Hong Kong Special Administration Region, we identified a CoV closely related to SARS-CoV (bat-SARS-CoV) from 23 (39%) of 59 anal swabs of wild Chinese horseshoe bats (<italic>Rhinolophus sinicus</italic>
) by using RT-PCR. Sequencing and analysis of three bat-SARS-CoV genomes from samples collected at different dates showed that bat-SARS-CoV is closely related to SARS-CoV from humans and civets. Phylogenetic analysis showed that bat-SARS-CoV formed a distinct cluster with SARS-CoV as group 2b CoV, distantly related to known group 2 CoV. Most differences between the bat-SARS-CoV and SARS-CoV genomes were observed in the spike genes, ORF 3 and ORF 8, which are the regions where most variations also were observed between human and civet SARS-CoV genomes. In addition, the presence of a 29-bp insertion in ORF 8 of bat-SARS-CoV genome, not in most human SARS-CoV genomes, suggests that it has a common ancestor with civet SARS-CoV. Antibody against recombinant bat-SARS-CoV nucleocapsid protein was detected in 84% of Chinese horseshoe bats by using an enzyme immunoassay. Neutralizing antibody to human SARS-CoV also was detected in bats with lower viral loads. Precautions should be exercised in the handling of these animals.</p>
</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004888 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 004888 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= Main |étape= Merge |type= RBID |clé= PMC:1236580 |texte= Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:16169905" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |