In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infection.
Identifieur interne : 001924 ( Main/Merge ); précédent : 001923; suivant : 001925In-vitro renal epithelial cell infection reveals a viral kidney tropism as a potential mechanism for acute renal failure during Middle East Respiratory Syndrome (MERS) Coronavirus infection.
Auteurs : Isabella Eckerle ; Marcel A. Müller ; Stephan Kallies ; Daniel N. Gotthardt ; Christian Drosten [Allemagne]Source :
- Virology journal [ 1743-422X ] ; 2013.
Descripteurs français
- KwdFr :
- MESH :
- physiologie : Coronavirus.
- virologie : Atteinte rénale aigüe, Cellules épithéliales.
- Adulte, Adulte d'âge moyen, Cellules cultivées, Humains, Infections à coronavirus, Mâle, Sujet âgé, Tropisme viral.
English descriptors
- KwdEn :
- MESH :
- complications : Coronavirus Infections.
- physiology : Coronavirus.
- virology : Acute Kidney Injury, Epithelial Cells.
- Adult, Aged, Cells, Cultured, Humans, Male, Middle Aged, Viral Tropism.
Abstract
The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes symptoms similar to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), yet involving an additional component of acute renal failure (ARF) according to several published case reports. Impairment of the kidney is not typically seen in Coronavirus infections. The role of kidney infection in MERS is not understood.
DOI: 10.1186/1743-422X-10-359
PubMed: 24364985
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pubmed:24364985Le document en format XML
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<front><div type="abstract" xml:lang="en">The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) causes symptoms similar to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), yet involving an additional component of acute renal failure (ARF) according to several published case reports. Impairment of the kidney is not typically seen in Coronavirus infections. The role of kidney infection in MERS is not understood.</div>
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