Ident. | Authors (with country if any) | Title |
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000A85 (2019) |
Naoko Iwata-Yoshikawa [Japon] ; Tadashi Okamura [Japon] ; Yukiko Shimizu [Japon] ; Hideki Hasegawa [Japon] ; Makoto Takeda [Japon] ; Noriyo Nagata [Japon] | TMPRSS2 Contributes to Virus Spread and Immunopathology in the Airways of Murine Models after Coronavirus Infection. |
000C96 (2018) |
Alicia Regueiro-Ren ; Jacob J. Swidorski ; Zheng Liu ; Yan Chen ; Ny Sin ; Sing-Yuen Sit ; Jie Chen ; Brian L. Venables ; Juliang Zhu ; Beata Nowicka-Sans ; Tricia Protack ; Zeyu Lin ; Brian Terry ; Himadri Samanta ; Sharon Zhang ; Zhufang Li ; John Easter ; Brett R. Beno ; Vinod Arora ; Xiaohua S. Huang ; Sandhya Rahematpura ; Dawn D. Parker ; Roy Haskell ; Kenneth S. Santone ; Mark I. Cockett ; Mark Krystal ; Nicholas A. Meanwell ; Susan Jenkins ; Umesh Hanumegowda ; Ira B. Dicker | Design, Synthesis, and SAR of C-3 Benzoic Acid, C-17 Triterpenoid Derivatives. Identification of the HIV-1 Maturation Inhibitor 4-((1 R,3a S,5a R,5b R,7a R,11a S,11b R,13a R,13b R)-3a-((2-(1,1-Dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1 H-cyclopenta[ a]chrysen-9-yl)benzoic Acid (GSK3532795, BMS-955176). |
000E12 (2017) |
Stephen A. Goldstein [États-Unis] ; Joshua M. Thornbrough [États-Unis] ; Rong Zhang [États-Unis] ; Babal K. Jha [États-Unis] ; Yize Li [États-Unis] ; Ruth Elliott [États-Unis] ; Katherine Quiroz-Figueroa [États-Unis] ; Annie I. Chen [États-Unis] ; Robert H. Silverman [États-Unis] ; Susan R. Weiss [États-Unis] | Lineage A Betacoronavirus NS2 Proteins and the Homologous Torovirus Berne pp1a Carboxy-Terminal Domain Are Phosphodiesterases That Antagonize Activation of RNase L. |
000E77 (2017) |
Lisa E. Gralinski [États-Unis] ; Vineet D. Menachery [États-Unis] ; Andrew P. Morgan [États-Unis] ; Allison L. Totura [États-Unis] ; Anne Beall [États-Unis] ; Jacob Kocher [États-Unis] ; Jessica Plante [États-Unis] ; D. Corinne Harrison-Shostak [États-Unis] ; Alexandra Sch Fer [États-Unis] ; Fernando Pardo-Manuel De Villena [États-Unis] ; Martin T. Ferris [États-Unis] ; Ralph S. Baric [États-Unis] | Allelic Variation in the Toll-Like Receptor Adaptor Protein Ticam2 Contributes to SARS-Coronavirus Pathogenesis in Mice |
000F74 (2016) |
James Brett Case [États-Unis] ; Alison W. Ashbrook [États-Unis] ; Terence S. Dermody [États-Unis] ; Mark R. Denison [États-Unis] | Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity. |
001211 (2015) |
Allison L. Totura ; Alan Whitmore ; Sudhakar Agnihothram ; Alexandra Sch Fer ; Michael G. Katze ; Mark T. Heise ; Ralph S. Baric | Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection |
001902 (2013) |
Lisa E. Gralinski ; Armand Bankhead ; Sophia Jeng ; Vineet D. Menachery ; Sean Proll ; Sarah E. Belisle ; Melissa Matzke ; Bobbie-Jo M. Webb-Robertson ; Maria L. Luna ; Anil K. Shukla ; Martin T. Ferris ; Meagan Bolles ; Jean Chang ; Lauri Aicher ; Katrina M. Waters ; Richard D. Smith ; Thomas O. Metz ; G. Lynn Law ; Michael G. Katze ; Shannon Mcweeney ; Ralph S. Baric | Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury |
001C81 (2012) |
Bing Han ; Xuezhong Ma ; Jianhua Zhang ; Yu Zhang ; Xiaohui Bai ; David M. Hwang ; Shaf Keshavjee ; Gary A. Levy ; Ian Mcgilvray ; Mingyao Liu | Protective effects of long pentraxin PTX3 on lung injury in a severe acute respiratory syndrome model in mice |
001D03 (2012) |
Carly Page [États-Unis] ; Lindsay Goicochea ; Krystal Matthews ; Yong Zhang ; Peter Klover ; Michael J. Holtzman ; Lothar Hennighausen ; Matthew Frieman | Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection. |
001D48 (2012) |
Tanel Mahlak Iv [Allemagne] ; Daniel Ritz [Allemagne] ; Markus Mordstein [Allemagne] ; Marta L. Dediego [Espagne] ; Luis Enjuanes [Espagne] ; Marcel A. Müller [Allemagne] ; Christian Drosten [Allemagne] ; Peter Staeheli [Allemagne] | Combined action of type I and type III interferon restricts initial replication of severe acute respiratory syndrome coronavirus in the lung but fails to inhibit systemic virus spread. |
002457 (2010) |
Matthew B. Frieman [États-Unis] ; Jun Chen [États-Unis] ; Thomas E. Morrison [États-Unis] ; Alan Whitmore [États-Unis] ; William Funkhouser [États-Unis] ; Jerrold M. Ward [États-Unis] ; Elaine W. Lamirande [États-Unis] ; Anjeanette Roberts [États-Unis] ; Mark Heise [États-Unis] ; Kanta Subbarao [États-Unis] ; Ralph S. Baric [États-Unis] | SARS-CoV Pathogenesis Is Regulated by a STAT1 Dependent but a Type I, II and III Interferon Receptor Independent Mechanism |
002508 (2010) |
Markus Mordstein [Allemagne] ; Eva Neugebauer ; Vanessa Ditt ; Birthe Jessen ; Toni Rieger ; Valeria Falcone ; Frederic Sorgeloos ; Stephan Ehl ; Daniel Mayer ; Georg Kochs ; Martin Schwemmle ; Stephan Günther ; Christian Drosten ; Thomas Michiels ; Peter Staeheli | Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections. |
002570 (2010) |
Shigeru Kyuwa [Japon] ; Satoshi Takagaki ; Shutoku Matsuyama ; Fumihiro Taguchi ; Junzo Saegusa ; Yoichiroh Iwakura ; Yoh-Ichi Tagawa ; Yasuhiro Yoshikawa | Characterization of a variant virus from ascitic fluid of subacute granulomatous serositis in interferon-gamma-deficient C57BL/6 mice persistently infected with murine coronavirus strain JHM. |
002A77 (2009) |
Alexandre Jacques [Canada] ; Christian Bleau ; Claire Turbide ; Nicole Beauchemin ; Lucie Lamontagne | Macrophage interleukin-6 and tumour necrosis factor-alpha are induced by coronavirus fixation to Toll-like receptor 2/heparan sulphate receptors but not carcinoembryonic cell adhesion antigen 1a. |
002A78 (2009) |
Yu Lei [États-Unis] ; Chris B. Moore ; Rachael M. Liesman ; Brian P. O'Connor ; Daniel T. Bergstralh ; Zhijian J. Chen ; Raymond J. Pickles ; Jenny P-Y Ting | MAVS-mediated apoptosis and its inhibition by viral proteins. |
003069 (2008) |
Timothy Sheahan [États-Unis] ; Thomas E. Morrison [États-Unis] ; William Funkhouser [États-Unis] ; Satoshi Uematsu [Japon] ; Shizou Akira [Japon] ; Ralph S. Baric [États-Unis] ; Mark T. Heise [États-Unis] | MyD88 Is Required for Protection from Lethal Infection with a Mouse-Adapted SARS-CoV |
003741 (2007) |
Roland Züst [Suisse] ; Luisa Cervantes-Barragán ; Thomas Kuri ; Gjon Blakqori ; Friedemann Weber ; Burkhard Ludewig ; Volker Thiel | Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines. |
004C74 (2005) |
Yumiko Imai [Autriche] ; Keiji Kuba [Autriche] ; Shuan Rao [République populaire de Chine] ; Yi Huan [République populaire de Chine] ; Feng Guo [République populaire de Chine] ; Bin Guan [République populaire de Chine] ; Peng Yang [République populaire de Chine] ; Renu Sarao [Autriche] ; Teiji Wada [Autriche] ; Howard Leong-Poi [Canada] ; Michael A. Crackower [Canada] ; Akiyoshi Fukamizu [Japon] ; Chi-Chung Hui [Canada] ; Lutz Hein [Allemagne] ; Stefan Uhlig [Allemagne] ; Arthur S. Slutsky [Canada] ; Chengyu Jiang [République populaire de Chine] ; Josef M. Penninger [Autriche] | Angiotensin-converting enzyme 2 protects from severe acute lung failure |
005250 (2004) |
William G. Glass [États-Unis] ; Kanta Subbarao ; Brian Murphy ; Philip M. Murphy | Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice. |