| Ident. | Authors (with country if any) | Title |
|---|
| 000B54 (2019) |
Tong Zhao [République populaire de Chine] ; Qing Meng [République populaire de Chine] ; Dongwei Kang [République populaire de Chine] ; Jianbo Ji [République populaire de Chine] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Xinyong Liu [République populaire de Chine] ; Peng Zhan [République populaire de Chine] | Discovery of novel indolylarylsulfones as potent HIV-1 NNRTIs via structure-guided scaffold morphing. |
| 000C96 (2018) |
Alicia Regueiro-Ren ; Jacob J. Swidorski ; Zheng Liu ; Yan Chen ; Ny Sin ; Sing-Yuen Sit ; Jie Chen ; Brian L. Venables ; Juliang Zhu ; Beata Nowicka-Sans ; Tricia Protack ; Zeyu Lin ; Brian Terry ; Himadri Samanta ; Sharon Zhang ; Zhufang Li ; John Easter ; Brett R. Beno ; Vinod Arora ; Xiaohua S. Huang ; Sandhya Rahematpura ; Dawn D. Parker ; Roy Haskell ; Kenneth S. Santone ; Mark I. Cockett ; Mark Krystal ; Nicholas A. Meanwell ; Susan Jenkins ; Umesh Hanumegowda ; Ira B. Dicker | Design, Synthesis, and SAR of C-3 Benzoic Acid, C-17 Triterpenoid Derivatives. Identification of the HIV-1 Maturation Inhibitor 4-((1 R,3a S,5a R,5b R,7a R,11a S,11b R,13a R,13b R)-3a-((2-(1,1-Dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1 H-cyclopenta[ a]chrysen-9-yl)benzoic Acid (GSK3532795, BMS-955176). |
| 001051 (2016) |
Qing Meng [République populaire de Chine] ; Xuwang Chen [République populaire de Chine] ; Dongwei Kang [République populaire de Chine] ; Boshi Huang [République populaire de Chine] ; Wenxin Li [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Dirk Daelemans [Belgique] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Xinyong Liu [République populaire de Chine] | Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket. |
| 001052 (2016) |
Jiapei Yang [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Dongwei Kang [République populaire de Chine] ; Xueyi Lu [République populaire de Chine] ; Xiao Li [République populaire de Chine] ; Zhaoqiang Liu [République populaire de Chine] ; Boshi Huang [République populaire de Chine] ; Dirk Daelemans [Belgique] ; Christophe Pannecouque [Belgique] ; Erik De Clercq [Belgique] ; Peng Zhan [République populaire de Chine] ; Xinyong Liu [République populaire de Chine] | Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket. |
| 001228 (2015) |
Denong Wang ; Jin Tang ; Jiulai Tang ; Lai-Xi Wang [États-Unis] | Targeting N-Glycan Cryptic Sugar Moieties for Broad-Spectrum Virus Neutralization: Progress in Identifying Conserved Molecular Targets in Viruses of Distinct Phylogenetic Origins |
| 001648 (2014) |
Liu Wang [République populaire de Chine] ; Ye Tian [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Hong Liu [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Dongyue Li [République populaire de Chine] ; Huiqing Liu [République populaire de Chine] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Xinyong Liu [République populaire de Chine] | Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 2: discovery of novel [1,2,4]Triazolo[1,5-a]pyrimidines using a structure-guided core-refining approach. |
| 001A01 (2013) |
Guangyu Zhao [République populaire de Chine] ; Lanying Du ; Cuiqing Ma ; Ye Li ; Lin Li ; Vincent Km Poon ; Lili Wang ; Fei Yu ; Bo-Jian Zheng ; Shibo Jiang ; Yusen Zhou | A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV. |
| 002024 (2011) |
Pei-Yu Liao [États-Unis] ; Yong Seok Choi ; Jonathan D. Dinman ; Kelvin H. Lee | The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed -1 ribosomal frameshifting. |
| 002A60 (2009) |
Andrea Spallarossa [Italie] ; Sara Cesarini ; Angelo Ranise ; Silvia Schenone ; Olga Bruno ; Alberto Borassi ; Paolo La Colla ; Margherita Pezzullo ; Giuseppina Sanna ; Gabriella Collu ; Barbara Secci ; Roberta Loddo | Parallel synthesis, molecular modelling and further structure-activity relationship studies of new acylthiocarbamates as potent non-nucleoside HIV-1 reverse transcriptase inhibitors. |
| 002F83 (2008) |
Sara Cesarini [Italie] ; Andrea Spallarossa ; Angelo Ranise ; Paola Fossa ; Paolo La Colla ; Giuseppina Sanna ; Gabriella Collu ; Roberta Loddo | Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors. Part 1: Parallel synthesis, molecular modelling and structure-activity relationship studies on O-[2-(hetero)arylethyl]-N-phenylthiocarbamates. |
| 003C31 (2006) |
Feng-Biao Guo ; Chun-Ting Zhang | ZCURVE_V: a new self-training system for recognizing protein-coding genes in viral and phage genomes |
| 003D75 (2006) |
Qiuying Huang ; Yangjian Cheng ; Qiwei Guo ; Qingge Li | Preparation of a chimeric armored RNA as a versatile calibrator for multiple virus assays. |
| 004711 (2005) |
Ian Brierley [Royaume-Uni] ; Francisco J. Dos Ramos [Royaume-Uni] | Programmed ribosomal frameshifting in HIV-1 and the SARS–CoV |
| 004D62 (2005) |
Caterina Fattorusso [Italie] ; Sandra Gemma [Italie] ; Stefania Butini [Italie] ; Paul Huleatt [Italie] ; Bruno Catalanotti [Italie] ; Marco Persico [Italie] ; Meri De Angelis [Italie] ; Isabella Fiorini [Italie] ; V Ito Nacci [Italie] ; Anna Ramunno [Italie] ; Manuela Rodriquez [Italie] ; Giovanni Greco [Italie] ; Ettore Novellino [Italie] ; Alberto Bergamini [Italie] ; Stefano Marini [Italie] ; Massimo Coletta [Italie] ; Giovanni Maga [Italie] ; Silvio Spadari [Italie] ; Giuseppe Campiani [Italie] | Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity |
| 005064 (2004) |
Ling Yi ; Zhengquan Li ; Kehu Yuan ; Xiuxia Qu ; Jian Chen ; Guangwen Wang ; Hong Zhang ; Hongpeng Luo ; Lili Zhu ; Pengfei Jiang ; Lirong Chen ; Yan Shen ; Min Luo ; Guoying Zuo ; Jianhe Hu ; Deliang Duan ; Yuchun Nie ; Xuanling Shi ; Wei Wang ; Yang Han ; Taisheng Li ; Yuqing Liu ; Mingxiao Ding ; Hongkui Deng ; Xiaojie Xu | Small Molecules Blocking the Entry of Severe Acute Respiratory Syndrome Coronavirus into Host Cells |
| 005395 (2004) |
Hongchao Lu [République populaire de Chine] ; Yi Zhao [République populaire de Chine] ; Jingfen Zhang [République populaire de Chine] ; Yuelan Wang [République populaire de Chine] ; Wei Li [République populaire de Chine] ; Xiaopeng Zhu [République populaire de Chine] ; Shiwei Sun [République populaire de Chine] ; Jingyi Xu [République populaire de Chine] ; Lunjiang Ling [République populaire de Chine] ; Lun Cai [République populaire de Chine] ; Dongbo Bu [République populaire de Chine] ; Runsheng Chen [République populaire de Chine] | Date of origin of the SARS coronavirus strains |
| 005A74 (2004) |
Michael J. Moore [États-Unis] ; Tatyana Dorfman [États-Unis] ; WENHUI LI [États-Unis] ; SWEE KEE WONG [États-Unis] ; YANHAN LI [République populaire de Chine] ; Jens H. Kuhn [États-Unis, Allemagne] ; James Coderre [États-Unis] ; Natalya Vasilieva [États-Unis] ; ZHONGCHAO HAN [République populaire de Chine] ; Thomas C. Greenough [États-Unis] ; Michael Farzan [États-Unis] ; HYERYUN CHOE [États-Unis] | Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2 |
| 006092 (2003) |
Andreas J. Kesel [Allemagne] | A system of protein target sequences for anti-RNA-viral chemotherapy by a vitamin B6-derived zinc-chelating trioxa-adamantane-triol. |
