Ident. | Authors (with country if any) | Title |
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001289 (2015) |
Sakshi Tomar ; Melanie L. Johnston [États-Unis] ; Sarah E. St John ; Heather L. Osswald [États-Unis] ; Prasanth R. Nyalapatla [États-Unis] ; Lake N. Paul ; Arun K. Ghosh [États-Unis] ; Mark R. Denison [États-Unis] ; Andrew D. Mesecar [États-Unis] | Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS. |
001335 (2015) |
Sheng Liu [République populaire de Chine] ; Wanxing Wei [République populaire de Chine] ; Yubin Li [République populaire de Chine] ; Xu Liu [République populaire de Chine] ; Xiaoji Cao [République populaire de Chine] ; Kechan Lei [République populaire de Chine] ; Min Zhou [République populaire de Chine] | Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents. |
001337 (2015) |
Li-Jun Wang ; Hao Chen ; Yun-Bao Ma ; Xiao-Yan Huang ; Chang-An Geng ; Xue-Mei Zhang ; Ji-Jun Chen [République populaire de Chine] | Design, synthesis and biological evaluation of caudatin analogs as potent hepatitis B virus inhibitors. |
001364 (2015) |
Aidang Lu [République populaire de Chine] ; Ziwen Wang ; Zhenghong Zhou ; Jianxin Chen ; Qingmin Wang | Application of "hydrogen bonding interaction" in new drug development: design, synthesis, antiviral activity, and SARs of thiourea derivatives. |
001365 (2015) |
Aidang Lu [République populaire de Chine] ; Yuanyuan Ma [République populaire de Chine] ; Ziwen Wang [République populaire de Chine] ; Zhenghong Zhou [République populaire de Chine] ; Qingmin Wang [République populaire de Chine] | Application of "Hydrogen-Bonding Interaction" in Drug Design. Part 2: Design, Synthesis, and Structure-Activity Relationships of Thiophosphoramide Derivatives as Novel Antiviral and Antifungal Agents. |
001412 (2015) |
Jingjing Gao [République populaire de Chine] ; Xianjin Luo [République populaire de Chine] ; Yuhuan Li [République populaire de Chine] ; Rongmei Gao [République populaire de Chine] ; Haifeng Chen [République populaire de Chine] ; Dingjue Ji [République populaire de Chine] | Synthesis and Biological Evaluation of 2‐oxo‐pyrazine‐3‐carboxamide‐yl Nucleoside Analogues and Their Epimers as Inhibitors of Influenza A Viruses |
001530 (2014) |
Yahira M. Báez-Santos [États-Unis] ; Scott J. Barraza ; Michael W. Wilson ; Michael P. Agius ; Anna M. Mielech ; Nicole M. Davis ; Susan C. Baker ; Scott D. Larsen ; Andrew D. Mesecar | X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases. |
001557 (2014) |
Hao Chen [République populaire de Chine] ; Yun-Bao Ma [République populaire de Chine] ; Xiao-Yan Huang [République populaire de Chine] ; Chang-An Geng [République populaire de Chine] ; Yong Zhao [République populaire de Chine] ; Li-Jun Wang [République populaire de Chine] ; Rui-Hua Guo [République populaire de Chine] ; Wen-Juan Liang [République populaire de Chine] ; Xue-Mei Zhang [République populaire de Chine] ; Ji-Jun Chen [République populaire de Chine] | Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. |
001664 (2014) |
Bo Su [République populaire de Chine] ; Fazhong Chen ; Lizhong Wang ; Qingmin Wang | Design, synthesis, antiviral activity, and structure-activity relationships (SARs) of two types of structurally novel phenanthroindo/quinolizidine analogues. |
001665 (2014) |
Bo Su [République populaire de Chine] ; Chunlong Cai [République populaire de Chine] ; Meng Deng [République populaire de Chine] ; Demin Liang [République populaire de Chine] ; Lizhong Wang [République populaire de Chine] ; Qingmin Wang [République populaire de Chine] | Design, synthesis, antiviral activity, and SARs of 13a-substituted phenanthroindolizidine alkaloid derivatives. |
001666 (2014) |
Ziwen Wang [République populaire de Chine] ; Anzheng Feng ; Mingbo Cui ; Yuxiu Liu ; Lizhong Wang ; Qingmin Wang | Design, synthesis, anti-tobacco mosaic virus (TMV) activity, and SARs of 7-methoxycryptopleurine derivatives. |
001849 (2013) |
Dmytro Havrylyuk [Ukraine] ; Borys Zimenkovsky ; Olexandr Vasylenko ; Craig W. Day ; Donald F. Smee ; Philippe Grellier ; Roman Lesyk | Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones. |
001920 (2013) |
Daniela Meyer [Allemagne] ; Frank Sielaff ; Maya Hammami ; Eva Böttcher-Friebertsh User ; Wolfgang Garten ; Torsten Steinmetzer | Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation. |
001954 (2013) |
Mark Turlington [États-Unis] ; Aspen Chun ; Sakshi Tomar ; Aimee Eggler ; Valerie Grum-Tokars ; Jon Jacobs ; J Scott Daniels ; Eric Dawson ; Adrian Saldanha ; Peter Chase ; Yahira M. Baez-Santos ; Craig W. Lindsley ; Peter Hodder ; Andrew D. Mesecar ; Shaun R. Stauffer | Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. |
001965 (2013) |
Mi Kyoung Kim [Corée du Sud] ; Hyunjun Yoon ; Dale Lynn Barnard ; Youhoon Chong | Design, synthesis and antiviral activity of 2-(3-amino-4-piperazinylphenyl)chromone derivatives. |
001C45 (2012) |
Li-Jun Wang [République populaire de Chine] ; Chang-An Geng ; Yun-Bao Ma ; Xiao-Yan Huang ; Jie Luo ; Hao Chen ; Rui-Hua Guo ; Xue-Mei Zhang ; Ji-Jun Chen | Synthesis, structure-activity relationships and biological evaluation of caudatin derivatives as novel anti-hepatitis B virus agents. |
001C46 (2012) |
Li-Jun Wang [République populaire de Chine] ; Chang-An Geng ; Yun-Bao Ma ; Xiao-Yan Huang ; Jie Luo ; Hao Chen ; Xue-Mei Zhang ; Ji-Jun Chen | Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents. |
001C47 (2012) |
Hye Ri Park [Corée du Sud] ; Hyunjun Yoon ; Mi Kyoung Kim ; Sung Dae Lee ; Youhoon Chong | Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV). |
001D04 (2012) |
Yan-Fei Qi [République populaire de Chine] ; Hong Zhang ; Juan Wang ; Yanfang Jiang ; Jinhua Li ; Ye Yuan ; Shiyao Zhang ; Kun Xu ; Yangguang Li ; Juan Li ; Junqi Niu ; Enbo Wang | In vitro anti-hepatitis B and SARS virus activities of a titanium-substituted-heteropolytungstate. |
001D38 (2012) |
Ziwen Wang [République populaire de Chine] ; Lei Wang ; Shuang Ma ; Yuxiu Liu ; Lizhong Wang ; Qingmin Wang | Design, synthesis, antiviral activity, and SARs of 14-aminophenanthroindolizidines. |
002018 (2011) |
Andrew V. Stachulski [Royaume-Uni] ; Chandrakala Pidathala ; Eleanor C. Row ; Raman Sharma ; Neil G. Berry ; Alexandre S. Lawrenson ; Shelley L. Moores ; Mazhar Iqbal ; Joanne Bentley ; Sarah A. Allman ; Geoffrey Edwards ; Alison Helm ; Jennifer Hellier ; Brent E. Korba ; J Edward Semple ; Jean-Francois Rossignol | Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication. |