| 004408 (2006) |
Syaulan Yang [Taïwan] ; Shu-Jen Chen [Taïwan] ; Min-Feng Hsu [Taïwan] ; Jen-Dar Wu [Taïwan] ; Chien-Te K. Tseng [États-Unis] ; Yu-Fan Liu [Taïwan] ; Hua-Chien Chen [Taïwan] ; Chun-Wei Kuo [Taïwan] ; Chi-Shen Wu [Taïwan] ; Li-Wen Chang [Taïwan] ; Wen-Chang Chen [Taïwan] ; Shao-Ying Liao [Taïwan] ; Teng-Yuan Chang [Taïwan] ; Hsin-Hui Hung [Taïwan] ; Hui-Lin Shr [Taïwan] ; Cheng-Yuan Liu [Taïwan] ; Yu-An Huang [Taïwan] ; Ling-Yin Chang [Taïwan] ; Jen-Chi Hsu [Taïwan] ; Clarence J. Peters [États-Unis] ; Andrew H.-J. Wang [Taïwan] ; Ming-Chu Hsu [Taïwan] | Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor |
| 000579 (2020) |
Young Sup Shin [Corée du Sud] ; Dnyandev B. Jarhad [Corée du Sud] ; Min Hwan Jang [Corée du Sud] ; Kristina Kovacikova [Pays-Bas] ; Gyudong Kim [Corée du Sud] ; Ji-Seong Yoon [Corée du Sud] ; Hong-Rae Kim [Corée du Sud] ; Young Eum Hyun [Corée du Sud] ; Amol S. Tipnis [Corée du Sud] ; Tong-Shin Chang [Corée du Sud] ; Martijn J. Van Hemert [Pays-Bas] ; Lak Shin Jeong [Corée du Sud] | Identification of 6'-β-fluoro-homoaristeromycin as a potent inhibitor of chikungunya virus replication. |
| 000B18 (2019) |
Seri Jo ; Suwon Kim ; Dong Hae Shin ; Mi-Sun Kim | Inhibition of SARS-CoV 3CL protease by flavonoids |
| 000D60 (2017) |
Lu Yu [République populaire de Chine] ; Xiuhai Gan [République populaire de Chine] ; Dagui Zhou [République populaire de Chine] ; Fangcheng He [République populaire de Chine] ; Song Zeng [République populaire de Chine] ; Deyu Hu [République populaire de Chine] | Synthesis and Antiviral Activity of Novel 1,4-Pentadien-3-one Derivatives Containing a 1,3,4-Thiadiazole Moiety. |
| 001049 (2016) |
Sheng Liu [République populaire de Chine] ; Yubin Li [République populaire de Chine] ; Wanxing Wei [République populaire de Chine] ; Kuiwu Wang [République populaire de Chine] ; Lisheng Wang [République populaire de Chine] ; Jianyi Wang [République populaire de Chine] | Design, synthesis, molecular docking studies and anti-HBV activity of phenylpropanoid derivatives. |
| 001239 (2015) |
Qi-Fei Zhong [République populaire de Chine] ; Rui Liu [République populaire de Chine] ; Gang Liu [République populaire de Chine] | Structure-activity relationship studies on quinoxalin-2(1H)-one derivatives containing thiazol-2-amine against hepatitis C virus leading to the discovery of BH6870. |
| 001337 (2015) |
Li-Jun Wang ; Hao Chen ; Yun-Bao Ma ; Xiao-Yan Huang ; Chang-An Geng ; Xue-Mei Zhang ; Ji-Jun Chen [République populaire de Chine] | Design, synthesis and biological evaluation of caudatin analogs as potent hepatitis B virus inhibitors. |
| 001965 (2013) |
Mi Kyoung Kim [Corée du Sud] ; Hyunjun Yoon ; Dale Lynn Barnard ; Youhoon Chong | Design, synthesis and antiviral activity of 2-(3-amino-4-piperazinylphenyl)chromone derivatives. |
| 003672 (2007) |
Qi-Shi Du [République populaire de Chine] ; Hao Sun ; Kuo-Chen Chou | Inhibitor design for SARS coronavirus main protease based on "distorted key theory". |
| 003F24 (2006) |
Pamela Hamill [Canada] ; Derek Hudson ; Richard Y. Kao ; Polly Chow ; Meera Raj ; Hongyan Xu ; Martin J. Richer ; François Jean | Development of a red-shifted fluorescence-based assay for SARS-coronavirus 3CL protease: identification of a novel class of anti-SARS agents from the tropical marine sponge Axinella corrugata. |
| 004085 (2006) |
Christophe Biot [Belgique, France] ; Wassim Daher [Belgique] ; Natascha Chavain [Belgique] ; Thierry Fandeur [Belgique] ; Jamal Khalife [Belgique] ; Daniel Dive [Belgique] ; Erik De Clercq [Belgique] | Design and Synthesis of Hydroxyferroquine Derivatives with Antimalarial and Antiviral Activities |
| 004476 (2006) |
Chung K. Chu [États-Unis] ; Srinivas Gadthula [États-Unis] ; XIN CHEN [États-Unis] ; HYUNAH CHOO [États-Unis] ; Sureyya Olgen [États-Unis] ; Dale L. Barnard [États-Unis] ; Robert W. Sidwell [États-Unis] | Antiviral activity of nucleoside analogues against SARS-coronavirus (SARS-CoV) |
| 004A02 (2005) |
Arun K. Ghosh [Géorgie (pays), États-Unis] ; Kai Xi [Géorgie (pays), États-Unis] ; Kiira Ratia [Géorgie (pays)] ; Bernard D. Santarsiero [Géorgie (pays)] ; Wentao Fu [Géorgie (pays)] ; Brian H. Harcourt [Géorgie (pays)] ; Paul A. Rota [Géorgie (pays)] ; Susan C. Baker [Géorgie (pays)] ; Michael E. Johnson [Géorgie (pays)] ; Andrew D. Mesecar [Géorgie (pays)] | Design and Synthesis of Peptidomimetic Severe Acute Respiratory Syndrome Chymotrypsin-like Protease Inhibitors |
| 004D50 (2005) |
Andreas J. Kesel [Allemagne] | Synthesis of novel test compounds for antiviral chemotherapy of severe acute respiratory syndrome (SARS) |
| 004E72 (2005) |
Gerold Hoever [Allemagne] ; Lidia Baltina [Russie] ; Martin Michaelis [Allemagne] ; Rimma Kondratenko [Russie] ; Lia Baltina [Russie] ; Genrich A. Tolstikov [Russie] ; Hans W. Doerr [Allemagne] ; Jindrich Jr Cinatl [Allemagne] | Antiviral activity of glycyrrhizic acid derivatives against SARS-coronavirus |
| 005306 (2004) |
Richard Y. Kao [République populaire de Chine] ; Wayne H W. Tsui ; Terri S W. Lee ; Julian A. Tanner ; Rory M. Watt ; Jian-Dong Huang ; Lihong Hu ; Guanhua Chen ; Zhiwei Chen ; Linqi Zhang ; Tian He ; Kwok-Hung Chan ; Herman Tse ; Amanda P C. To ; Louisa W Y. Ng ; Bonnie C W. Wong ; Hoi-Wah Tsoi ; Dan Yang ; David D. Ho ; Kwok-Yung Yuen | Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics. |
| 005503 (2004) |
Rajendram V. Rajnarayanan [États-Unis] ; Sivanesan Dakshanamurthy ; Nagarajan Pattabiraman | "Teaching old drugs to kill new bugs": structure-based discovery of anti-SARS drugs. |
| 006678 (????) |
O B Kazakova ; G V Giniiatullina ; G A Tolstikov | [Synthesis of A-secomethylenamino- and substituted amidoximotriterpenoids]. |
| 000720 (2020) |
Han Ju [République populaire de Chine] ; Siyu Xiu [République populaire de Chine] ; Xiao Ding [République populaire de Chine] ; Min Shang [République populaire de Chine] ; Ruifang Jia [République populaire de Chine] ; Bing Huang [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Xinyong Liu [République populaire de Chine] | Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity. |
| 000B70 (2019) |
Ren-Jun Wu [République populaire de Chine] ; Kai-Xuan Zhou [République populaire de Chine] ; Haijin Yang [République populaire de Chine] ; Guo-Qing Song [République populaire de Chine] ; Yong-Hong Li [République populaire de Chine] ; Jia-Xin Fu [République populaire de Chine] ; Xiao Zhang [République populaire de Chine] ; Shu-Jing Yu [République populaire de Chine] ; Li-Zhong Wang [République populaire de Chine] ; Li-Xia Xiong [République populaire de Chine] ; Cong-Wei Niu [République populaire de Chine] ; Fu-Hang Song [République populaire de Chine] ; Haitao Yang [République populaire de Chine] ; Jian-Guo Wang [République populaire de Chine] | Chemical synthesis, crystal structure, versatile evaluation of their biological activities and molecular simulations of novel pyrithiobac derivatives. |
| 000D59 (2017) |
Kuanglei Wang [République populaire de Chine] ; Fei Yang [République populaire de Chine] ; Lihui Wang [République populaire de Chine] ; Kemin Liu [République populaire de Chine] ; Lu Sun [République populaire de Chine] ; Bin Lin [République populaire de Chine] ; Yaping Hu [République populaire de Chine] ; Boyu Wang [République populaire de Chine] ; Maosheng Cheng [République populaire de Chine] ; Yongshou Tian [République populaire de Chine] | Synthesis and biological evaluation of NH2-acyl oseltamivir analogues as potent neuraminidase inhibitors. |
| 000D63 (2017) |
Sumei Li [République populaire de Chine] ; Xiuhua Jia [République populaire de Chine] ; Xintian Shen [République populaire de Chine] ; Zhuwen Wei [République populaire de Chine] ; Zhiyan Jiang [République populaire de Chine] ; Yixian Liao [République populaire de Chine] ; Yiming Guo [République populaire de Chine] ; Xiaojun Zheng [République populaire de Chine] ; Guohua Zhong [République populaire de Chine] ; Gaopeng Song [République populaire de Chine] | Structure-activity relationships of 3-O-β-chacotriosyl oleanic acid derivatives as entry inhibitors for highly pathogenic H5N1 influenza virus. |
| 000D98 (2017) |
Xianmin Lan [République populaire de Chine] ; Dandan Xie [République populaire de Chine] ; Limin Yin [République populaire de Chine] ; Zhenzhen Wang [République populaire de Chine] ; Jin Chen [République populaire de Chine] ; Awei Zhang [République populaire de Chine] ; Baoan Song [République populaire de Chine] ; Deyu Hu [République populaire de Chine] | Novel α,β-unsaturated amide derivatives bearing α-amino phosphonate moiety as potential antiviral agents. |
| 000E50 (2017) |
Li Wang [République populaire de Chine] ; Bo-Bo Bao [République populaire de Chine] ; Guo-Qing Song [République populaire de Chine] ; Cheng Chen [République populaire de Chine] ; Xu-Meng Zhang [République populaire de Chine] ; Wei Lu [République populaire de Chine] ; Zefang Wang [République populaire de Chine] ; Yan Cai [République populaire de Chine] ; Shuang Li [République populaire de Chine] ; Sheng Fu [République populaire de Chine] ; Fu-Hang Song [République populaire de Chine] ; Haitao Yang [République populaire de Chine] ; Jian-Guo Wang [République populaire de Chine] | Discovery of unsymmetrical aromatic disulfides as novel inhibitors of SARS-CoV main protease: Chemical synthesis, biological evaluation, molecular docking and 3D-QSAR study |
| 000F42 (2016) |
Bo Su [République populaire de Chine] ; Chunlong Cai [République populaire de Chine] ; Meng Deng [République populaire de Chine] ; Qingmin Wang [République populaire de Chine] | Spatial Configuration and Three-Dimensional Conformation Directed Design, Synthesis, Antiviral Activity, and Structure-Activity Relationships of Phenanthroindolizidine Analogues. |
| 001042 (2016) |
Wensheng Yu [États-Unis] ; Ling Tong [États-Unis] ; Bin Hu [République populaire de Chine] ; Bin Zhong [République populaire de Chine] ; Jinglai Hao [République populaire de Chine] ; Tao Ji [République populaire de Chine] ; Shuai Zan [République populaire de Chine] ; Craig A. Coburn [États-Unis] ; Oleg Selyutin [États-Unis] ; Lei Chen [États-Unis] ; Laura Rokosz [États-Unis] ; Sony Agrawal [États-Unis] ; Rong Liu [États-Unis] ; Stephanie Curry [États-Unis] ; Patricia Mcmonagle [États-Unis] ; Paul Ingravallo [États-Unis] ; Ernest Asante-Appiah [États-Unis] ; Shiying Chen [États-Unis] ; Joseph A. Kozlowski [États-Unis] | Discovery of Chromane Containing Hepatitis C Virus (HCV) NS5A Inhibitors with Improved Potency against Resistance-Associated Variants. |
| 001071 (2016) |
Ji-Young Park [Corée du Sud] ; Jin-A Ko [Corée du Sud] ; Dae Wook Kim ; Young Min Kim [Corée du Sud] ; Hyung-Jun Kwon [Corée du Sud] ; Hyung Jae Jeong [Corée du Sud] ; Cha Young Kim [Corée du Sud] ; Ki Hun Park ; Woo Song Lee [Corée du Sud] ; Young Bae Ryu [Corée du Sud] | Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV. |
| 001232 (2015) |
Elena V. Tretyakova [Russie] ; Irina E. Smirnova [Russie] ; Elena V. Salimova [Russie] ; Victor N. Odinokov [Russie] | Synthesis and antiviral activity of maleopimaric and quinopimaric acids' derivatives. |
| 001335 (2015) |
Sheng Liu [République populaire de Chine] ; Wanxing Wei [République populaire de Chine] ; Yubin Li [République populaire de Chine] ; Xu Liu [République populaire de Chine] ; Xiaoji Cao [République populaire de Chine] ; Kechan Lei [République populaire de Chine] ; Min Zhou [République populaire de Chine] | Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents. |
| 001336 (2015) |
Hannah L. Peters [États-Unis] ; Dirk Jochmans [Belgique] ; Adriaan H. De Wilde [Pays-Bas] ; Clara C. Posthuma [Pays-Bas] ; Eric J. Snijder [Pays-Bas] ; Johan Neyts [Belgique] ; Katherine L. Seley-Radtke [États-Unis] | Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity. |
| 001364 (2015) |
Aidang Lu [République populaire de Chine] ; Ziwen Wang ; Zhenghong Zhou ; Jianxin Chen ; Qingmin Wang | Application of "hydrogen bonding interaction" in new drug development: design, synthesis, antiviral activity, and SARs of thiourea derivatives. |
| 001365 (2015) |
Aidang Lu [République populaire de Chine] ; Yuanyuan Ma [République populaire de Chine] ; Ziwen Wang [République populaire de Chine] ; Zhenghong Zhou [République populaire de Chine] ; Qingmin Wang [République populaire de Chine] | Application of "Hydrogen-Bonding Interaction" in Drug Design. Part 2: Design, Synthesis, and Structure-Activity Relationships of Thiophosphoramide Derivatives as Novel Antiviral and Antifungal Agents. |
| 001412 (2015) |
Jingjing Gao [République populaire de Chine] ; Xianjin Luo [République populaire de Chine] ; Yuhuan Li [République populaire de Chine] ; Rongmei Gao [République populaire de Chine] ; Haifeng Chen [République populaire de Chine] ; Dingjue Ji [République populaire de Chine] | Synthesis and Biological Evaluation of 2‐oxo‐pyrazine‐3‐carboxamide‐yl Nucleoside Analogues and Their Epimers as Inhibitors of Influenza A Viruses |
| 001557 (2014) |
Hao Chen [République populaire de Chine] ; Yun-Bao Ma [République populaire de Chine] ; Xiao-Yan Huang [République populaire de Chine] ; Chang-An Geng [République populaire de Chine] ; Yong Zhao [République populaire de Chine] ; Li-Jun Wang [République populaire de Chine] ; Rui-Hua Guo [République populaire de Chine] ; Wen-Juan Liang [République populaire de Chine] ; Xue-Mei Zhang [République populaire de Chine] ; Ji-Jun Chen [République populaire de Chine] | Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. |
| 001665 (2014) |
Bo Su [République populaire de Chine] ; Chunlong Cai [République populaire de Chine] ; Meng Deng [République populaire de Chine] ; Demin Liang [République populaire de Chine] ; Lizhong Wang [République populaire de Chine] ; Qingmin Wang [République populaire de Chine] | Design, synthesis, antiviral activity, and SARs of 13a-substituted phenanthroindolizidine alkaloid derivatives. |
| 001666 (2014) |
Ziwen Wang [République populaire de Chine] ; Anzheng Feng ; Mingbo Cui ; Yuxiu Liu ; Lizhong Wang ; Qingmin Wang | Design, synthesis, anti-tobacco mosaic virus (TMV) activity, and SARs of 7-methoxycryptopleurine derivatives. |
| 001954 (2013) |
Mark Turlington [États-Unis] ; Aspen Chun ; Sakshi Tomar ; Aimee Eggler ; Valerie Grum-Tokars ; Jon Jacobs ; J Scott Daniels ; Eric Dawson ; Adrian Saldanha ; Peter Chase ; Yahira M. Baez-Santos ; Craig W. Lindsley ; Peter Hodder ; Andrew D. Mesecar ; Shaun R. Stauffer | Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. |
| 001C46 (2012) |
Li-Jun Wang [République populaire de Chine] ; Chang-An Geng ; Yun-Bao Ma ; Xiao-Yan Huang ; Jie Luo ; Hao Chen ; Xue-Mei Zhang ; Ji-Jun Chen | Synthesis, biological evaluation and structure-activity relationships of glycyrrhetinic acid derivatives as novel anti-hepatitis B virus agents. |
| 001D04 (2012) |
Yan-Fei Qi [République populaire de Chine] ; Hong Zhang ; Juan Wang ; Yanfang Jiang ; Jinhua Li ; Ye Yuan ; Shiyao Zhang ; Kun Xu ; Yangguang Li ; Juan Li ; Junqi Niu ; Enbo Wang | In vitro anti-hepatitis B and SARS virus activities of a titanium-substituted-heteropolytungstate. |
| 002436 (2010) |
Iou-Jiun Kang [République populaire de Chine] ; Li-Wen Wang ; Teng-Kuang Yeh ; Chung-Chi Lee ; Yen-Chun Lee ; Sheng-Ju Hsu ; Yen-Shian Wu ; Jing-Chyi Wang ; Yu-Sheng Chao ; Andrew Yueh ; Jyh-Haur Chern | Synthesis, activity, and pharmacokinetic properties of a series of conformationally-restricted thiourea analogs as novel hepatitis C virus inhibitors. |
| 002450 (2010) |
Arun K. Ghosh [États-Unis] ; Jun Takayama [États-Unis] ; Kalapala Venkateswara Rao [États-Unis] ; Kiira Ratia [États-Unis] ; Rima Chaudhuri [États-Unis] ; Debbie C. Mulhearn [États-Unis] ; Hyun Lee [États-Unis] ; Daniel B. Nichols [États-Unis] ; Surendranath Baliji [États-Unis] ; Susan C. Baker [États-Unis] ; Michael E. Johnson [États-Unis] ; Andrew D. Mesecar [États-Unis] | Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Novel Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation |
| 002469 (2010) |
Holger Steuber [Allemagne] ; Rolf Hilgenfeld | Recent advances in targeting viral proteases for the discovery of novel antivirals. |
| 002A66 (2009) |
Thomas Regnier [Japon] ; Diganta Sarma ; Koushi Hidaka ; Usman Bacha ; Ernesto Freire ; Yoshio Hayashi ; Yoshiaki Kiso | New developments for the design, synthesis and biological evaluation of potent SARS-CoV 3CL(pro) inhibitors. |
| 002B44 (2009) |
Iou-Jiun Kang [République populaire de Chine] ; Li-Wen Wang ; Sheng-Ju Hsu ; Chung-Chi Lee ; Yen-Chun Lee ; Yen-Shian Wu ; Andrew Yueh ; Jing-Chyi Wang ; Tsu-An Hsu ; Yu-Sheng Chao ; Jyh-Haur Chern | Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors. |
| 002F06 (2009) |
Arun K. Ghosh [États-Unis] ; Jun Takayama [États-Unis] ; Yoann Aubin [États-Unis] ; Kiira Ratia [États-Unis] ; Rima Chaudhuri [États-Unis] ; Yahira Baez [États-Unis] ; Katrina Sleeman [États-Unis] ; Melissa Coughlin [États-Unis] ; Daniel B. Nichols [États-Unis] ; Debbie C. Mulhearn [États-Unis] ; Bellur S. Prabhakar [États-Unis] ; Susan C. Bakery [États-Unis] ; Michael E. Johnson [États-Unis] ; Andrew D. Mesecar [États-Unis] | Structure-Based Design, Synthesis, and Biological Evaluation of a Series of Novel and Reversible Inhibitors for the Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Protease |
| 003584 (2007) |
D H Goetz [États-Unis] ; Y. Choe ; E. Hansell ; Y T Chen ; M. Mcdowell ; C B Jonsson ; W R Roush ; J. Mckerrow ; C S Craik | Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus. |
| 003B93 (2007) |
Masahiro Ikejiri [Japon] ; Takayuki Ohshima [Japon] ; Keizo Kato [Japon] ; Masaaki Toyama [Japon] ; Takayuki Murata [Japon] ; Kunitada Shimotohno [Japon] ; Tokumi Maruyama [Japon] | 5'-O-Masked 2'-deoxyadenosine analogues as lead compounds for hepatitis C virus (HCV) therapeutic agents |
| 003D57 (2006) |
Luhua Lai [République populaire de Chine] ; Xiaofeng Han ; Hao Chen ; Ping Wei ; Changkang Huang ; Shiyong Liu ; Keqiang Fan ; Lu Zhou ; Zhenming Liu ; Jianfeng Pei ; Ying Liu | Quaternary structure, substrate selectivity and inhibitor design for SARS 3C-like proteinase. |
| 003E02 (2006) |
Pi-Hui Liang [Taïwan] ; Wei-Chieh Cheng ; Yi-Ling Lee ; Han-Pang Yu ; Ying-Ta Wu ; Yi-Ling Lin ; Chi-Huey Wong | Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis. |
| 003F15 (2006) |
Haitao Yang [République populaire de Chine] ; Mark Bartlam ; Zihe Rao | Drug design targeting the main protease, the Achilles' heel of coronaviruses. |
| 003F82 (2006) |
D-Q Wei [République populaire de Chine] ; R. Zhang ; Q-S Du ; W-N Gao ; Y. Li ; H. Gao ; S-Q Wang ; X. Zhang ; A-X Li ; S. Sirois ; K-C Chou | Anti-SARS drug screening by molecular docking. |
| 004080 (2006) |
Rakesh Kumar [Canada] ; Wassila Semaine [Canada] ; Monika Johar [Canada] ; D. Lorne J. Tyrrell [Canada] ; Babita Agrawal [Canada] | Effect of Various Pyrimidines Possessing the 1-[(2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl] Moiety, Able To Mimic Natural 2‘-Deoxyribose, on Wild-type and Mutant Hepatitis B Virus Replication |
| 004196 (2006) |
Jan Balzarini [Belgique] ; Els Keyaerts [Belgique] ; Leen Vijgen [Belgique] ; Frank Vandermeer [Pays-Bas] ; Miguel Stevens [Belgique] ; Erik De Clercq [Belgique] ; Herman Egberink [Pays-Bas] ; Marc Van Ranst [Belgique] | Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture |
| 004463 (2006) |
Han-Zhong Zhang [États-Unis] ; HONG ZHANG [États-Unis] ; William Kemnitzer [États-Unis] ; Ben Tseng [États-Unis] ; Jindrich Jr Cinatl [Allemagne] ; Martin Michaelis [Allemagne] ; Hans Wilhelm Doerr [Allemagne] ; SUI XIONG CAI [États-Unis] | Design and synthesis of dipeptidyl glutaminyl fluoromethyl ketones as potent severe acute respiratory syndrome coronovirus (SARS-CoV) inhibitors |
| 004864 (2005) |
Nicholas A. Meanwell [États-Unis] ; Makonen Belema ; David J. Carini ; Stanley V. D'Andrea ; John F. Kadow ; Mark Krystal ; B Narasimhulu Naidu ; Alicia Regueiro-Ren ; Paul M. Scola ; Sing-Yuen Sit ; Michael A. Walker ; Tao Wang ; Kap-Sun Yeung | Developments in antiviral drug design, discovery and development in 2004. |
| 004998 (2005) |
Jiun-Jie Shie [États-Unis] ; Jim-Min Fang [États-Unis, Taïwan] ; Chih-Jung Kuo [États-Unis] ; Tun-Hsun Kuo [États-Unis] ; Po-Huang Liang [États-Unis, Taïwan] ; Hung-Jyun Huang [États-Unis] ; Wen-Bin Yang [États-Unis] ; Chun-Hung Lin [États-Unis] ; Jiun-Ling Chen [États-Unis] ; Yin-Ta Wu [États-Unis] ; Chi-Huey Wong [États-Unis] | Discovery of Potent Anilide Inhibitors against the Severe Acute Respiratory Syndrome 3CL Protease |
| 000109 (2020) |
Inder P. Singh [Inde] ; Shiv Gupta [Inde] ; Sanjay Kumar [Inde] | Thiazole Compounds as Antiviral Agents: An Update. |
| 000B45 (2019) |
Kouji Ohnishi [Japon] ; Yasunao Hattori [Japon] ; Kazuya Kobayashi [Japon] ; Kenichi Akaji [Japon] | Evaluation of a non-prime site substituent and warheads combined with a decahydroisoquinolin scaffold as a SARS 3CL protease inhibitor. |
| 000F69 (2016) |
Yuanchao Xie ; Comfort Alicha Ogah ; Xiangrui Jiang ; Jianfeng Li ; Jingshan Shen [République populaire de Chine] | Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review. |
| 001007 (2016) |
Vathan Kumar [Taïwan] ; Kian-Pin Tan [Taïwan] ; Ying-Ming Wang [Taïwan] ; Sheng-Wei Lin [Taïwan] ; Po-Huang Liang [Taïwan] | Identification, synthesis and evaluation of SARS-CoV and MERS-CoV 3C-like protease inhibitors. |
| 001050 (2016) |
Bao-Long Chen [République populaire de Chine] ; Ya-Jing Wang [République populaire de Chine] ; Hong Guo [République populaire de Chine] ; Guang-Yao Zeng [République populaire de Chine] | Design, synthesis, and biological evaluation of crenatoside analogues as novel influenza neuraminidase inhibitors. |
| 001051 (2016) |
Qing Meng [République populaire de Chine] ; Xuwang Chen [République populaire de Chine] ; Dongwei Kang [République populaire de Chine] ; Boshi Huang [République populaire de Chine] ; Wenxin Li [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Dirk Daelemans [Belgique] ; Erik De Clercq [Belgique] ; Christophe Pannecouque [Belgique] ; Xinyong Liu [République populaire de Chine] | Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket. |
| 001230 (2015) |
Chang-An Geng [République populaire de Chine] ; Xiao-Yan Huang [République populaire de Chine] ; Yun-Bao Ma [République populaire de Chine] ; Xue-Mei Zhang [République populaire de Chine] ; Ji-Jun Chen [République populaire de Chine] | Synthesis of erythrocentaurin derivatives as a new class of hepatitis B virus inhibitors. |
| 001234 (2015) |
Nobuko Mibu ; Kazumi Yokomizo ; Hatsumi Aki ; Norimasa Ota ; Hiroyuki Fujii ; Ai Yuzuriha ; Shiori Saneyoshi ; Aoi Tanaka ; Airi Koga ; Jianrong Zhou ; Takeshi Miyata ; Kunihiro Sumoto | Synthesis and Antiviral Evaluation of Some C(3)-Symmetrical Trialkoxy-Substituted 1,3,5-Triazines and Their Molecular Geometry. |
| 001272 (2015) |
Jun-Li Yang [Corée du Sud] ; Thi-Kim-Quy Ha ; Basanta Dhodary ; Euisun Pyo ; Ngoc Hieu Nguyen ; Hyomoon Cho ; Eunhee Kim ; Won Keun Oh | Oleanane triterpenes from the flowers of Camellia japonica inhibit porcine epidemic diarrhea virus (PEDV) replication. |
| 001291 (2015) |
Yong Zhao [République populaire de Chine] ; Chang-An Geng [République populaire de Chine] ; Hao Chen [République populaire de Chine] ; Yun-Bao Ma [République populaire de Chine] ; Xiao-Yan Huang [République populaire de Chine] ; Tuan-Wu Cao [République populaire de Chine] ; Kang He [République populaire de Chine] ; Hao Wang [République populaire de Chine] ; Xue-Mei Zhang [République populaire de Chine] ; Ji-Jun Chen [République populaire de Chine] | Isolation, synthesis and anti-hepatitis B virus evaluation of p-hydroxyacetophenone derivatives from Artemisia capillaris. |
| 001530 (2014) |
Yahira M. Báez-Santos [États-Unis] ; Scott J. Barraza ; Michael W. Wilson ; Michael P. Agius ; Anna M. Mielech ; Nicole M. Davis ; Susan C. Baker ; Scott D. Larsen ; Andrew D. Mesecar | X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases. |
| 001652 (2014) |
Adeyemi O. Adedeji [États-Unis] ; Kamalendra Singh [États-Unis] ; Ademola Kassim [États-Unis] ; Christopher M. Coleman [États-Unis] ; Ruth Elliott [États-Unis] ; Susan R. Weiss [États-Unis] ; Matthew B. Frieman [États-Unis] ; Stefan G. Sarafianos [États-Unis] | Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses. |
| 001664 (2014) |
Bo Su [République populaire de Chine] ; Fazhong Chen ; Lizhong Wang ; Qingmin Wang | Design, synthesis, antiviral activity, and structure-activity relationships (SARs) of two types of structurally novel phenanthroindo/quinolizidine analogues. |
| 001700 (2014) |
Xiao Li [République populaire de Chine] ; Xueyi Lu [République populaire de Chine] ; Wenmin Chen [République populaire de Chine] ; Huiqing Liu [République populaire de Chine] ; Peng Zhan [République populaire de Chine] ; Christophe Pannecouque [Belgique] ; Jan Balzarini [Belgique] ; Erik De Clercq [Belgique] ; Xinyong Liu [République populaire de Chine] | Arylazolyl(azinyl)thioacetanilides. Part 16: Structure-based bioisosterism design, synthesis and biological evaluation of novel pyrimidinylthioacetanilides as potent HIV-1 inhibitors. |
| 001849 (2013) |
Dmytro Havrylyuk [Ukraine] ; Borys Zimenkovsky ; Olexandr Vasylenko ; Craig W. Day ; Donald F. Smee ; Philippe Grellier ; Roman Lesyk | Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones. |
| 001955 (2013) |
Meng Wu [République populaire de Chine] ; Ziwen Wang ; Chuisong Meng ; Kailiang Wang ; Yanna Hu ; Lizhong Wang ; Qingmin Wang | Discovery and SARs of trans-3-aryl acrylic acids and their analogs as novel anti-tobacco mosaic virus (TMV) agents. |
| 001C45 (2012) |
Li-Jun Wang [République populaire de Chine] ; Chang-An Geng ; Yun-Bao Ma ; Xiao-Yan Huang ; Jie Luo ; Hao Chen ; Rui-Hua Guo ; Xue-Mei Zhang ; Ji-Jun Chen | Synthesis, structure-activity relationships and biological evaluation of caudatin derivatives as novel anti-hepatitis B virus agents. |
| 001C47 (2012) |
Hye Ri Park [Corée du Sud] ; Hyunjun Yoon ; Mi Kyoung Kim ; Sung Dae Lee ; Youhoon Chong | Synthesis and antiviral evaluation of 7-O-arylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV). |
| 002010 (2011) |
Qiaoli Li [République populaire de Chine] ; Zhenhuan Zhao ; Dihan Zhou ; Yaoqing Chen ; Wei Hong ; Luyang Cao ; Jingyi Yang ; Yan Zhang ; Wei Shi ; Zhijian Cao ; Yingliang Wu ; Huimin Yan ; Wenxin Li | Virucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses. |
| 002018 (2011) |
Andrew V. Stachulski [Royaume-Uni] ; Chandrakala Pidathala ; Eleanor C. Row ; Raman Sharma ; Neil G. Berry ; Alexandre S. Lawrenson ; Shelley L. Moores ; Mazhar Iqbal ; Joanne Bentley ; Sarah A. Allman ; Geoffrey Edwards ; Alison Helm ; Jennifer Hellier ; Brent E. Korba ; J Edward Semple ; Jean-Francois Rossignol | Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication. |
| 002037 (2011) |
Rui-Hua Guo [République populaire de Chine] ; Quan Zhang ; Yun-Bao Ma ; Jie Luo ; Chang-An Geng ; Li-Jun Wang ; Xue-Mei Zhang ; Jun Zhou ; Zhi-Yong Jiang ; Ji-Jun Chen | Structure-activity relationships study of 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one derivatives as novel non-nucleoside anti-hepatitis B virus agents. |
| 002165 (2011) |
Mi Kyoung Kim [Corée du Sud] ; Mi-Sun Yu ; Hye Ri Park ; Kyung Bo Kim ; Chaewoon Lee ; Suh Young Cho ; Jihoon Kang ; Hyunjun Yoon ; Dong-Eun Kim ; Hyunah Choo ; Yong-Joo Jeong ; Youhoon Chong | 2,6-Bis-arylmethyloxy-5-hydroxychromones with antiviral activity against both hepatitis C virus (HCV) and SARS-associated coronavirus (SCV). |
| 002437 (2010) |
R. Ramajayam [Taïwan] ; Kian-Pin Tan ; Hun-Ge Liu ; Po-Huang Liang | Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors. |
| 002934 (2010) |
Cheng-Wei Yang [Taïwan] ; Yue-Zhi Lee [Taïwan] ; Iou-Jiun Kang [Taïwan] ; Dale L. Bamard [États-Unis] ; Jia-Tsrong Jan [Taïwan] ; DU LIN [Taïwan] ; Chun-Wei Huang [Taïwan] ; Teng-Kuang Yeh [Taïwan] ; Yu-Sheng Chao [Taïwan] ; Shiow-Ju Lee [Taïwan] | Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus |
| 002A86 (2009) |
Chaewoon Lee [Corée du Sud] ; Jin Moo Lee ; Na-Ra Lee ; Dong-Eun Kim ; Yong-Joo Jeong ; Youhoon Chong | Investigation of the pharmacophore space of Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) NTPase/helicase by dihydroxychromone derivatives. |
| 003059 (2008) |
Monica R. Loizzo [Italie] ; Antoine M. Saab ; Rosa Tundis ; Giancarlo A. Statti ; Francesco Menichini ; Ilaria Lampronti ; Roberto Gambari ; Jindrich Cinatl ; Hans Wilhelm Doerr | Phytochemical analysis and in vitro antiviral activities of the essential oils of seven Lebanon species. |
| 003133 (2008) |
Qingang Yang [République populaire de Chine] ; Lili Chen ; Xuchang He ; Zhenting Gao ; Xu Shen ; Donglu Bai | Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors. |
| 003159 (2008) |
Jianmin Zhang [Canada] ; Carly Huitema ; Chunying Niu ; Jiang Yin ; Michael N G. James ; Lindsay D. Eltis ; John C. Vederas | Aryl methylene ketones and fluorinated methylene ketones as reversible inhibitors for severe acute respiratory syndrome (SARS) 3C-like proteinase. |
| 003173 (2008) |
Kiira Ratia [États-Unis] ; Scott Pegan ; Jun Takayama ; Katrina Sleeman ; Melissa Coughlin ; Surendranath Baliji ; Rima Chaudhuri ; Wentao Fu ; Bellur S. Prabhakar ; Michael E. Johnson ; Susan C. Baker ; Arun K. Ghosh ; Andrew D. Mesecar | A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. |
| 003511 (2008) |
Arun K. Ghosh [États-Unis] ; GANGLI GONG [États-Unis] ; Valerie Grum-Tokars [États-Unis] ; Debbie C. Mulhearn [États-Unis] ; Susan C. Baker [États-Unis] ; Melissa Coughlin [États-Unis] ; Bellur S. Prabhakar [États-Unis] ; Katrina Sleeman [États-Unis] ; Michael E. Johnson [États-Unis] ; Andrew D. Mesecar [États-Unis] | Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors |
| 003763 (2007) |
Nan Yang [République populaire de Chine] ; Julian A. Tanner ; Bo-Jian Zheng ; Rory M. Watt ; Ming-Liang He ; Lin-Yu Lu ; Jie-Qing Jiang ; Ka-To Shum ; Yong-Ping Lin ; Kin-Ling Wong ; Marie C M. Lin ; Hsiang-Fu Kung ; Hongzhe Sun ; Jian-Dong Huang | Bismuth complexes inhibit the SARS coronavirus. |
| 003C78 (2006) |
Jong Hyun Cho [États-Unis] ; Dale L. Bernard ; Robert W. Sidwell ; Earl R. Kern ; Chung K. Chu | Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS. |
| 003F80 (2006) |
Masahiro Ikejiri [Japon] ; Masayuki Saijo ; Shigeru Morikawa ; Shuetsu Fukushi ; Tetsuya Mizutani ; Ichiro Kurane ; Tokumi Maruyama | Anti-SARS-CoV activity of nucleoside analogs having 6-chloropurine as a nucleobase. |
| 004409 (2006) |
Yue-Qing Li [République populaire de Chine] ; Ze-Lin Li [République populaire de Chine] ; Wei-Jie Zhao [République populaire de Chine] ; Rui-Xing Wen [République populaire de Chine] ; Qing-Wei Meng [République populaire de Chine] ; YI ZENG [République populaire de Chine] | Synthesis of stilbene derivatives with inhibition of SARS coronavirus replication |
| 004451 (2006) |
Andrea J. Dooley [États-Unis] ; Nice Shindo [États-Unis] ; Barbara Taggart [États-Unis] ; Jewn-Giew Park [États-Unis] ; Yuan-Ping Pang [États-Unis] | From genome to drug lead : Identification of a small-molecule inhibitor of the SARS virus |
| 004455 (2006) |
Dale L. Barnard [États-Unis] ; Craig W. Day [États-Unis] ; Kevin Bailey [États-Unis] ; Matthew Heiner [États-Unis] ; Robert Montgomery [États-Unis] ; Larry Lauridsen [États-Unis] ; Paul K. S. Chan [Hong Kong] ; Robert W. Sidwell [États-Unis] | Evaluation of immunomodulators, interferons and known in vitro SARS-CoV inhibitors for inhibition of SARS-CoV replication in BALB/c mice |
| 004596 (2005) |
Julian A. Tanner [République populaire de Chine] ; Bo-Jian Zheng ; Jie Zhou ; Rory M. Watt ; Jie-Qing Jiang ; Kin-Ling Wong ; Yong-Ping Lin ; Lin-Yu Lu ; Ming-Liang He ; Hsiang-Fu Kung ; Andreas J. Kesel ; Jian-Dong Huang | The adamantane-derived bananins are potent inhibitors of the helicase activities and replication of SARS coronavirus. |
| 004903 (2005) |
Lili Chen ; Chunshan Gui ; Xiaomin Luo ; Qingang Yang ; Stephan Günther ; Elke Scandella ; Christian Drosten ; Donglu Bai ; Xichang He ; Burkhard Ludewig ; Jing Chen ; Haibin Luo ; Yiming Yang ; Yifu Yang ; Jianping Zou ; Volker Thiel ; Kaixian Chen ; Jianhua Shen ; Xu Shen ; Hualiang Jiang | Cinanserin Is an Inhibitor of the 3C-Like Proteinase of Severe Acute Respiratory Syndrome Coronavirus and Strongly Reduces Virus Replication In Vitro† |
| 004923 (2005) |
Qishi Du [République populaire de Chine] ; Shuqing Wang ; Zhiqin Jiang ; Weina Gao ; Yun Li ; Dongqing Wei ; Kuo-Chen Chou | Application of bioinformatics in search for cleavable peptides of SARS-CoV M(pro) and chemical modification of octapeptides. |
| 004E02 (2005) |
Masayuki Saijo [Japon] ; Shigeru Morikawa [Japon] ; Shuetsu Fukushi [Japon] ; Tetsuya Mizutani [Japon] ; Hideki Hasegawa [Japon] ; Noriyo Nagata [Japon] ; Naoko Iwata [Japon] ; Ichiro Kurane [Japon] | Inhibitory effect of mizoribine and ribavirin on the replication of severe acute respiratory syndrome (SARS)-associated coronavirus |
| 004E41 (2005) |
Tania Ivens [Belgique] ; Christel Van Den Eynde [Belgique] ; Koen Van Acker [Belgique] ; Erik Nijs [Belgique] ; Géry Dams [Belgique] ; Eva Bettens [Belgique] ; Asa Ohagen [Belgique] ; Rudi Pauwels [Belgique] ; Kurt Hertogs [Belgique] | Development of a homogeneous screening assay for automated detection of antiviral agents active against severe acute respiratory syndrome-associated coronavirus |
| 006392 (2003) |
Ekachai Jenwitheesuk [États-Unis] ; Ram Samudrala [États-Unis] | Identifying inhibitors of the SARS coronavirus proteinase |
| 006767 (????) |
Q-Y Yang [République populaire de Chine] ; X-Y Tian ; W-S Fang | Bioactive coumarins from Boenninghausenia sessilicarpa. |
| 000147 (2020) |
Calvin J. Gordon [Canada] ; Egor P. Tchesnokov [Canada] ; Joy Y. Feng [États-Unis] ; Danielle P. Porter [États-Unis] ; Matthias Götte [Canada] | The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus. |
