Serveur d'exploration SRAS

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Le cluster Carly Huitema - Lindsay D. Eltis

Terms

9Carly Huitema
10Lindsay D. Eltis
9John C. Vederas

Associations

Freq.WeightAssociation
90.949Carly Huitema - Lindsay D. Eltis
70.778Carly Huitema - John C. Vederas
70.738John C. Vederas - Lindsay D. Eltis

Documents par ordre de pertinence
003102 (2008) Carly Huitema [Canada] ; Jianmin Zhang ; Jiang Yin ; Michael N G. James ; John C. Vederas ; Lindsay D. EltisHeteroaromatic ester inhibitors of hepatitis A virus 3C proteinase: Evaluation of mode of action.
003159 (2008) Jianmin Zhang [Canada] ; Carly Huitema ; Chunying Niu ; Jiang Yin ; Michael N G. James ; Lindsay D. Eltis ; John C. VederasAryl methylene ketones and fluorinated methylene ketones as reversible inhibitors for severe acute respiratory syndrome (SARS) 3C-like proteinase.
003500 (2008) Carly Huitema [Canada] ; JIANMIN ZHANG [Canada] ; JIANG YIN [Canada] ; Michael N. G. James [Canada] ; John C. Vederas [Canada] ; Lindsay D. Eltis [Canada]Heteroaromatic ester inhibitors of hepatitis A virus 3C proteinase : Evaluation of mode of action
003784 (2007) Jiang Yin [Canada] ; Chunying Niu [Canada] ; Maia M. Cherney [Canada] ; Jianmin Zhang [Canada] ; Carly Huitema [Canada] ; Lindsay D. Eltis [Canada] ; John C. Vederas [Canada] ; Michael N. G. James [Canada]A Mechanistic View of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-like Peptidase
003B78 (2007) JIANMIN ZHANG [Canada] ; Hanna I. Pettersson [Canada] ; Carly Huitema [Canada] ; CHUNYING NIU [Canada] ; JIANG YIN [Canada] ; Michael N. G. James [Canada] ; Lindsay D. Eltis [Canada] ; John C. Vederas [Canada]Design, synthesis, and evaluation of inhibitors for severe acute respiratory syndrome 3C-like protease based on phthalhydrazide ketones or heteroaromatic esters
003F91 (2006) Jiang Yin [Canada] ; Maia M. Cherney ; Ernst M. Bergmann ; Jianmin Zhang ; Carly Huitema ; Hanna Pettersson ; Lindsay D. Eltis ; John C. Vederas ; Michael N G. JamesAn episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors.
005A58 (2004) Rajendra P. Jain [Canada] ; Hanna I. Pettersson ; JIANMIN ZHANG ; Katherine D. Aull ; Pascal D. Fortin ; Carly Huitema ; Lindsay D. Eltis ; Jonathan C. Parrish ; Michael N. G. James ; David S. Wishart ; John C. VederasSynthesis and evaluation of keto-glutamine analogues as potent inhibitors of severe acute respiratory syndrome 3CLpro
004875 (2005) Ting-Wai Lee [Canada] ; Maia M. Cherney ; Carly Huitema ; Jie Liu ; Karen Ellis James ; James C. Powers ; Lindsay D. Eltis ; Michael N G. JamesCrystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide.
005324 (2004) Jan E. Blanchard [Canada] ; Nadine H. Elowe ; Carly Huitema ; Pascal D. Fortin ; Jonathan D. Cechetto ; Lindsay D. Eltis ; Eric D. BrownHigh-throughput screening identifies inhibitors of the SARS coronavirus main proteinase.
003072 (2008) Chunying Niu [Canada] ; Jiang Yin ; Jianmin Zhang ; John C. Vederas ; Michael N G. JamesMolecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV Mpro.
003487 (2008) CHUNYING NIU [Canada] ; JIANG YIN [Canada] ; JIANMIN ZHANG [Canada] ; John C. Vederas [Canada] ; Michael N. G. James [Canada]Molecular docking identifies the binding of 3-chloropyridine moieties specifically to the S1 pocket of SARS-CoV Mpro
003736 (2007) Ting-Wai Lee [Canada] ; Maia M. Cherney ; Jie Liu ; Karen Ellis James ; James C. Powers ; Lindsay D. Eltis ; Michael N G. JamesCrystal structures reveal an induced-fit binding of a substrate-like Aza-peptide epoxide to SARS coronavirus main peptidase.

Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021