Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus
Identifieur interne : 001626 ( Main/Exploration ); précédent : 001625; suivant : 001627Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus
Auteurs : Marion Sevajol ; Lorenzo Subissi ; Etienne Decroly ; Bruno Canard ; Isabelle ImbertSource :
- Virus Research [ 0168-1702 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- enzymologie : Virus du SRAS.
- génétique : Virus du SRAS.
- métabolisme : ARN viral, Complexes multienzymatiques, Protéines virales, RNA replicase.
- physiologie : Virus du SRAS.
- Réplication virale, Transcription génétique.
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Multienzyme Complexes, RNA Replicase, RNA, Viral, Viral Proteins.
- enzymology : SARS Virus.
- genetics : SARS Virus.
- physiology : SARS Virus.
- Transcription, Genetic, Virus Replication.
Abstract
This review summarizes coronavirus RNA biochemistry mechanisms. A processivity factor for the viral RNA-dependent RNA polymerase. RNA proofreading through a viral 3′–5′ exonuclease. Viral capping regulator factors.
Url:
DOI: 10.1016/j.virusres.2014.10.008
PubMed: 25451065
PubMed Central: 7114481
Affiliations:
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Le document en format XML
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus</title>
<author><name sortKey="Sevajol, Marion" sort="Sevajol, Marion" uniqKey="Sevajol M" first="Marion" last="Sevajol">Marion Sevajol</name>
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<author><name sortKey="Subissi, Lorenzo" sort="Subissi, Lorenzo" uniqKey="Subissi L" first="Lorenzo" last="Subissi">Lorenzo Subissi</name>
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<author><name sortKey="Decroly, Etienne" sort="Decroly, Etienne" uniqKey="Decroly E" first="Etienne" last="Decroly">Etienne Decroly</name>
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<author><name sortKey="Canard, Bruno" sort="Canard, Bruno" uniqKey="Canard B" first="Bruno" last="Canard">Bruno Canard</name>
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<author><name sortKey="Imbert, Isabelle" sort="Imbert, Isabelle" uniqKey="Imbert I" first="Isabelle" last="Imbert">Isabelle Imbert</name>
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<series><title level="j">Virus Research</title>
<idno type="ISSN">0168-1702</idno>
<idno type="eISSN">1872-7492</idno>
<imprint><date when="2014">2014</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Multienzyme Complexes (metabolism)</term>
<term>RNA Replicase (metabolism)</term>
<term>RNA, Viral (metabolism)</term>
<term>SARS Virus (enzymology)</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (physiology)</term>
<term>Transcription, Genetic</term>
<term>Viral Proteins (metabolism)</term>
<term>Virus Replication</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (métabolisme)</term>
<term>Complexes multienzymatiques (métabolisme)</term>
<term>Protéines virales (métabolisme)</term>
<term>RNA replicase (métabolisme)</term>
<term>Réplication virale</term>
<term>Transcription génétique</term>
<term>Virus du SRAS (enzymologie)</term>
<term>Virus du SRAS (génétique)</term>
<term>Virus du SRAS (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Multienzyme Complexes</term>
<term>RNA Replicase</term>
<term>RNA, Viral</term>
<term>Viral Proteins</term>
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<keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>ARN viral</term>
<term>Complexes multienzymatiques</term>
<term>Protéines virales</term>
<term>RNA replicase</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Transcription, Genetic</term>
<term>Virus Replication</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Réplication virale</term>
<term>Transcription génétique</term>
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<front><div type="abstract" xml:lang="en"><title>Highlights</title>
<p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label>
<p id="par0005">This review summarizes coronavirus RNA biochemistry mechanisms.</p>
</list-item>
<list-item id="lsti0010"><label>•</label>
<p id="par0010">A processivity factor for the viral RNA-dependent RNA polymerase.</p>
</list-item>
<list-item id="lsti0015"><label>•</label>
<p id="par0015">RNA proofreading through a viral 3′–5′ exonuclease.</p>
</list-item>
<list-item id="lsti0020"><label>•</label>
<p id="par0020">Viral capping regulator factors.</p>
</list-item>
</list>
</p>
</div>
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<tree><noCountry><name sortKey="Canard, Bruno" sort="Canard, Bruno" uniqKey="Canard B" first="Bruno" last="Canard">Bruno Canard</name>
<name sortKey="Decroly, Etienne" sort="Decroly, Etienne" uniqKey="Decroly E" first="Etienne" last="Decroly">Etienne Decroly</name>
<name sortKey="Imbert, Isabelle" sort="Imbert, Isabelle" uniqKey="Imbert I" first="Isabelle" last="Imbert">Isabelle Imbert</name>
<name sortKey="Sevajol, Marion" sort="Sevajol, Marion" uniqKey="Sevajol M" first="Marion" last="Sevajol">Marion Sevajol</name>
<name sortKey="Subissi, Lorenzo" sort="Subissi, Lorenzo" uniqKey="Subissi L" first="Lorenzo" last="Subissi">Lorenzo Subissi</name>
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