Use of convalescent plasma therapy in SARS patients in Hong Kong
Identifieur interne : 005619 ( Main/Exploration ); précédent : 005618; suivant : 005620Use of convalescent plasma therapy in SARS patients in Hong Kong
Auteurs : Y. Cheng [Hong Kong] ; R. Wong [Hong Kong] ; Y. O. Y. Soo [Hong Kong] ; W. S. Wong [Hong Kong] ; C. K. Lee [Hong Kong] ; M. H. L. Ng [Hong Kong] ; P. Chan [Hong Kong] ; K. C. Wong [Hong Kong] ; C. B. Leung [Hong Kong] ; G. Cheng [Hong Kong]Source :
- European Journal of Clinical Microbiology and Infectious Diseases [ 0934-9723 ] ; 2005-01-01.
Descripteurs français
- KwdFr :
- Analyse de survie, Convalescence, Femelle, Hong Kong (épidémiologie), Humains, Immunothérapie (), Indice de gravité médicale, Maladies transmissibles émergentes (), Maladies transmissibles émergentes (diagnostic), Maladies transmissibles émergentes (épidémiologie), Modèles logistiques, Mâle, Probabilité, Résultat thérapeutique, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (épidémiologie), Transfusion de composants du sang (), Virus du SRAS (immunologie), Études par échantillonnage, Études rétrospectives, Évaluation des risques.
- MESH :
- diagnostic : Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
- immunologie : Virus du SRAS.
- épidémiologie : Hong Kong, Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
- Analyse de survie, Convalescence, Femelle, Humains, Immunothérapie, Indice de gravité médicale, Maladies transmissibles émergentes, Modèles logistiques, Mâle, Probabilité, Résultat thérapeutique, Syndrome respiratoire aigu sévère, Transfusion de composants du sang, Études par échantillonnage, Études rétrospectives, Évaluation des risques.
- Wicri :
- geographic : Hong Kong.
English descriptors
- KwdEn :
- Blood Component Transfusion (methods), Communicable Diseases, Emerging (diagnosis), Communicable Diseases, Emerging (epidemiology), Communicable Diseases, Emerging (therapy), Convalescence, Female, Hong Kong (epidemiology), Humans, Immunotherapy (methods), Logistic Models, Male, Probability, Retrospective Studies, Risk Assessment, SARS Virus (immunology), Sampling Studies, Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (therapy), Severity of Illness Index, Survival Analysis, Treatment Outcome.
- MESH :
- geographic , epidemiology : Hong Kong.
- diagnosis : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- epidemiology : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- immunology : SARS Virus.
- methods : Blood Component Transfusion, Immunotherapy.
- therapy : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- Convalescence, Female, Humans, Logistic Models, Male, Probability, Retrospective Studies, Risk Assessment, Sampling Studies, Severity of Illness Index, Survival Analysis, Treatment Outcome.
Abstract
Abstract: In order to evaluate the efficacy of convalescent plasma therapy in the treatment of patients with severe acute respiratory syndrome (SARS), 80 SARS patients were given convalescent plasma at Prince of Wales Hospital, Hong Kong, between 20 March and 26 May 2003. Good outcome was defined as discharge by day 22 following the onset of SARS symptoms. Poor outcome was defined as death or hospitalization beyond 22 days. A higher day-22 discharge rate was observed among patients who were given convalescent plasma before day 14 of illness (58.3% vs 15.6%; P<0.001) and among those who were PCR positive and seronegative for coronavirus at the time of plasma infusion (66.7% vs 20%; P=0.001).
Url:
- https://api.istex.fr/ark:/67375/VQC-KMM7R3X0-K/fulltext.pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088355
DOI: 10.1007/s10096-004-1271-9
Affiliations:
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Le document en format XML
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Y." last="Soo">Y. O. Y. Soo</name><affiliation wicri:level="4"><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Wong, W S" sort="Wong, W S" uniqKey="Wong W" first="W. S." last="Wong">W. S. Wong</name><affiliation wicri:level="4"><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong</wicri:regionArea><placeName><settlement type="city">Sha Tin</settlement></placeName><orgName type="university">Université chinoise de Hong Kong</orgName></affiliation></author><author><name sortKey="Lee, C K" sort="Lee, C K" uniqKey="Lee C" first="C. K." last="Lee">C. K. Lee</name><affiliation wicri:level="4"><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Paediatrics, The Chinese University of Hong Kong</wicri:regionArea><placeName><settlement type="city">Sha Tin</settlement></placeName><orgName type="university">Université chinoise de Hong Kong</orgName></affiliation></author><author><name sortKey="Ng, M H L" sort="Ng, M H L" uniqKey="Ng M" first="M. H. L." last="Ng">M. H. L. Ng</name><affiliation wicri:level="4"><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong</wicri:regionArea><placeName><settlement type="city">Sha Tin</settlement></placeName><orgName type="university">Université chinoise de Hong Kong</orgName></affiliation></author><author><name sortKey="Chan, P" sort="Chan, P" uniqKey="Chan P" first="P." last="Chan">P. 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échantillonnage</term><term>Études rétrospectives</term><term>Évaluation des risques</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Hong Kong</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Communicable Diseases, Emerging</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Maladies transmissibles émergentes</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Communicable Diseases, Emerging</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Blood Component Transfusion</term><term>Immunotherapy</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Communicable Diseases, Emerging</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Hong Kong</term><term>Maladies transmissibles émergentes</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Convalescence</term><term>Female</term><term>Humans</term><term>Logistic Models</term><term>Male</term><term>Probability</term><term>Retrospective Studies</term><term>Risk Assessment</term><term>Sampling Studies</term><term>Severity of Illness Index</term><term>Survival Analysis</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Analyse de survie</term><term>Convalescence</term><term>Femelle</term><term>Humains</term><term>Immunothérapie</term><term>Indice de gravité médicale</term><term>Maladies transmissibles émergentes</term><term>Modèles logistiques</term><term>Mâle</term><term>Probabilité</term><term>Résultat thérapeutique</term><term>Syndrome respiratoire aigu sévère</term><term>Transfusion de composants du sang</term><term>Études par échantillonnage</term><term>Études rétrospectives</term><term>Évaluation des risques</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Hong Kong</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: In order to evaluate the efficacy of convalescent plasma therapy in the treatment of patients with severe acute respiratory syndrome (SARS), 80 SARS patients were given convalescent plasma at Prince of Wales Hospital, Hong Kong, between 20 March and 26 May 2003. Good outcome was defined as discharge by day 22 following the onset of SARS symptoms. Poor outcome was defined as death or hospitalization beyond 22 days. A higher day-22 discharge rate was observed among patients who were given convalescent plasma before day 14 of illness (58.3% vs 15.6%; P<0.001) and among those who were PCR positive and seronegative for coronavirus at the time of plasma infusion (66.7% vs 20%; P=0.001).</div></front></TEI><affiliations><list><country><li>Hong Kong</li></country><settlement><li>Sha Tin</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="Hong Kong"><noRegion><name sortKey="Cheng, Y" sort="Cheng, Y" uniqKey="Cheng Y" first="Y." last="Cheng">Y. Cheng</name></noRegion><name sortKey="Chan, P" sort="Chan, P" uniqKey="Chan P" first="P." last="Chan">P. Chan</name><name sortKey="Cheng, G" sort="Cheng, G" uniqKey="Cheng G" first="G." last="Cheng">G. Cheng</name><name sortKey="Cheng, G" sort="Cheng, G" uniqKey="Cheng G" first="G." last="Cheng">G. Cheng</name><name sortKey="Lee, C K" sort="Lee, C K" uniqKey="Lee C" first="C. K." last="Lee">C. K. Lee</name><name sortKey="Leung, C B" sort="Leung, C B" uniqKey="Leung C" first="C. B." last="Leung">C. B. Leung</name><name sortKey="Ng, M H L" sort="Ng, M H L" uniqKey="Ng M" first="M. H. L." last="Ng">M. H. L. Ng</name><name sortKey="Soo, Y O Y" sort="Soo, Y O Y" uniqKey="Soo Y" first="Y. O. Y." last="Soo">Y. O. Y. Soo</name><name sortKey="Wong, K C" sort="Wong, K C" uniqKey="Wong K" first="K. C." last="Wong">K. C. Wong</name><name sortKey="Wong, R" sort="Wong, R" uniqKey="Wong R" first="R." last="Wong">R. Wong</name><name sortKey="Wong, W S" sort="Wong, W S" uniqKey="Wong W" first="W. S." last="Wong">W. S. Wong</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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