SrasV1, Main, Exploration, bibRecord, 005360

Evolutional insights on uncharacterized SARS coronavirus genes

Identifieur interne : 005360 ( Main/Exploration ); précédent : 005359; suivant : 005361

Evolutional insights on uncharacterized SARS coronavirus genes

Auteurs : Alex Inberg ; Michal Linial

Source :

Febs Letters [ 0014-5793 ] ; 2004.

RBID : PMC:7125658

Descripteurs français

KwdFr :
- Cadres ouverts de lecture, Données de séquences moléculaires, Gènes viraux, Similitude de séquences d'acides aminés, Séquence d'acides aminés, Virus du SRAS (génétique), Évolution biologique.
MESH :
- génétique : Virus du SRAS.
- Cadres ouverts de lecture, Données de séquences moléculaires, Gènes viraux, Similitude de séquences d'acides aminés, Séquence d'acides aminés, Évolution biologique.

English descriptors

KwdEn :
- Amino Acid Sequence, Biological Evolution, Genes, Viral, Molecular Sequence Data, Open Reading Frames, SARS Virus (genetics), Sequence Homology, Amino Acid.
MESH :
- genetics : SARS Virus.
- Amino Acid Sequence, Biological Evolution, Genes, Viral, Molecular Sequence Data, Open Reading Frames, Sequence Homology, Amino Acid.

Abstract

The complete genome of the severe acute respiratory syndrome coronavirus (SARS‐CoV) and many of its variants has been determined by several laboratories. The genome contains fourteen predicted open reading frames (ORFs). However, a function had been clearly assigned for only six of these ORFs, in the viral replication, transcription and structural constituents. The others are herein referred to as uncharacterized ORFs (UC‐ORFs). Here, we try to provide a relational insight on those UC‐ORFs, suggesting that a number of them are remotely related to structural proteins of coronaviruses and other viruses infecting mammalian hosts. Surprisingly, several of the UC‐ORFs exhibit considerable similarity with other SARS‐CoV ORFs. These observations may provide clues on the evolution and genome dynamics of the SARS‐CoV.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125658

DOI: 10.1016/j.febslet.2004.09.076
PubMed: 15527778
PubMed Central: 7125658

Affiliations:

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Serveur d'exploration SRAS

Evolutional insights on uncharacterized SARS coronavirus genes

Evolutional insights on uncharacterized SARS coronavirus genes

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration SRAS
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