The SARS-CoV S glycoprotein.
Identifieur interne : 005029 ( Main/Exploration ); précédent : 005028; suivant : 005030The SARS-CoV S glycoprotein.
Auteurs : X. Xiao [États-Unis] ; D S DimitrovSource :
- Cellular and molecular life sciences : CMLS [ 1420-682X ] ; 2004.
Descripteurs français
- KwdFr :
- Animaux, Fusion cellulaire, Glycoprotéine de spicule des coronavirus, Glycoprotéines (), Glycoprotéines membranaires (), Glycoprotéines membranaires (physiologie), Humains, Protéines de fusion virale, Protéines de l'enveloppe virale (), Protéines de l'enveloppe virale (physiologie), Structure tertiaire des protéines, Virus du SRAS (métabolisme).
- MESH :
- métabolisme : Virus du SRAS.
- physiologie : Glycoprotéines membranaires, Protéines de l'enveloppe virale.
- Animaux, Fusion cellulaire, Glycoprotéine de spicule des coronavirus, Glycoprotéines, Glycoprotéines membranaires, Humains, Protéines de fusion virale, Protéines de l'enveloppe virale, Structure tertiaire des protéines.
English descriptors
- KwdEn :
- Animals, Cell Fusion, Glycoproteins (chemistry), Humans, Membrane Glycoproteins (chemistry), Membrane Glycoproteins (physiology), Protein Structure, Tertiary, SARS Virus (metabolism), Spike Glycoprotein, Coronavirus, Viral Envelope Proteins (chemistry), Viral Envelope Proteins (physiology), Viral Fusion Proteins.
- MESH :
- chemical , chemistry : Glycoproteins, Membrane Glycoproteins, Viral Envelope Proteins.
- chemical , physiology : Membrane Glycoproteins, Viral Envelope Proteins.
- metabolism : SARS Virus.
- Animals, Cell Fusion, Humans, Protein Structure, Tertiary, Spike Glycoprotein, Coronavirus, Viral Fusion Proteins.
Abstract
The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. Recent rapid advances in our knowledge of the structure and function of this protein have lead to the development of a number of candidate vaccine immunogens and SARS-CoV entry inhibitors.
DOI: 10.1007/s00018-004-4257-y
PubMed: 15526150
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 002A64
- to stream PubMed, to step Curation: 002A64
- to stream PubMed, to step Checkpoint: 002992
- to stream Ncbi, to step Merge: 000B87
- to stream Ncbi, to step Curation: 000B87
- to stream Ncbi, to step Checkpoint: 000B87
- to stream Main, to step Merge: 005393
- to stream Main, to step Curation: 005029
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The SARS-CoV S glycoprotein.</title><author><name sortKey="Xiao, X" sort="Xiao, X" uniqKey="Xiao X" first="X" last="Xiao">X. Xiao</name><affiliation wicri:level="1"><nlm:affiliation>Protein Interactions Group, LECB, CCR, NCI-Frederick, NIH, Building 469, Room 105, Frederick, Maryland 21702-1201, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Protein Interactions Group, LECB, CCR, NCI-Frederick, NIH, Building 469, Room 105, Frederick, Maryland 21702-1201</wicri:regionArea><wicri:noRegion>Maryland 21702-1201</wicri:noRegion></affiliation></author><author><name sortKey="Dimitrov, D S" sort="Dimitrov, D S" uniqKey="Dimitrov D" first="D S" last="Dimitrov">D S Dimitrov</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2004">2004</date><idno type="RBID">pubmed:15526150</idno><idno type="pmid">15526150</idno><idno type="doi">10.1007/s00018-004-4257-y</idno><idno type="wicri:Area/PubMed/Corpus">002A64</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002A64</idno><idno type="wicri:Area/PubMed/Curation">002A64</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002A64</idno><idno type="wicri:Area/PubMed/Checkpoint">002992</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002992</idno><idno type="wicri:Area/Ncbi/Merge">000B87</idno><idno type="wicri:Area/Ncbi/Curation">000B87</idno><idno type="wicri:Area/Ncbi/Checkpoint">000B87</idno><idno type="wicri:doubleKey">1420-682X:2004:Xiao X:the:sars:cov</idno><idno type="wicri:Area/Main/Merge">005393</idno><idno type="wicri:Area/Main/Curation">005029</idno><idno type="wicri:Area/Main/Exploration">005029</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The SARS-CoV S glycoprotein.</title><author><name sortKey="Xiao, X" sort="Xiao, X" uniqKey="Xiao X" first="X" last="Xiao">X. Xiao</name><affiliation wicri:level="1"><nlm:affiliation>Protein Interactions Group, LECB, CCR, NCI-Frederick, NIH, Building 469, Room 105, Frederick, Maryland 21702-1201, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Protein Interactions Group, LECB, CCR, NCI-Frederick, NIH, Building 469, Room 105, Frederick, Maryland 21702-1201</wicri:regionArea><wicri:noRegion>Maryland 21702-1201</wicri:noRegion></affiliation></author><author><name sortKey="Dimitrov, D S" sort="Dimitrov, D S" uniqKey="Dimitrov D" first="D S" last="Dimitrov">D S Dimitrov</name></author></analytic><series><title level="j">Cellular and molecular life sciences : CMLS</title><idno type="ISSN">1420-682X</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Cell Fusion</term><term>Glycoproteins (chemistry)</term><term>Humans</term><term>Membrane Glycoproteins (chemistry)</term><term>Membrane Glycoproteins (physiology)</term><term>Protein Structure, Tertiary</term><term>SARS Virus (metabolism)</term><term>Spike Glycoprotein, Coronavirus</term><term>Viral Envelope Proteins (chemistry)</term><term>Viral Envelope Proteins (physiology)</term><term>Viral Fusion Proteins</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Fusion cellulaire</term><term>Glycoprotéine de spicule des coronavirus</term><term>Glycoprotéines ()</term><term>Glycoprotéines membranaires ()</term><term>Glycoprotéines membranaires (physiologie)</term><term>Humains</term><term>Protéines de fusion virale</term><term>Protéines de l'enveloppe virale ()</term><term>Protéines de l'enveloppe virale (physiologie)</term><term>Structure tertiaire des protéines</term><term>Virus du SRAS (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Glycoproteins</term><term>Membrane Glycoproteins</term><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Membrane Glycoproteins</term><term>Viral Envelope Proteins</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Glycoprotéines membranaires</term><term>Protéines de l'enveloppe virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Cell Fusion</term><term>Humans</term><term>Protein Structure, Tertiary</term><term>Spike Glycoprotein, Coronavirus</term><term>Viral Fusion Proteins</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Fusion cellulaire</term><term>Glycoprotéine de spicule des coronavirus</term><term>Glycoprotéines</term><term>Glycoprotéines membranaires</term><term>Humains</term><term>Protéines de fusion virale</term><term>Protéines de l'enveloppe virale</term><term>Structure tertiaire des protéines</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. Recent rapid advances in our knowledge of the structure and function of this protein have lead to the development of a number of candidate vaccine immunogens and SARS-CoV entry inhibitors.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Dimitrov, D S" sort="Dimitrov, D S" uniqKey="Dimitrov D" first="D S" last="Dimitrov">D S Dimitrov</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Xiao, X" sort="Xiao, X" uniqKey="Xiao X" first="X" last="Xiao">X. Xiao</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005029 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005029 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:15526150
|texte= The SARS-CoV S glycoprotein.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:15526150" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |