Comparative study of patients with and without SARS WHO fulfilled the WHO SARS case definition
Identifieur interne : 004890 ( Main/Exploration ); précédent : 004889; suivant : 004891Comparative study of patients with and without SARS WHO fulfilled the WHO SARS case definition
Auteurs : Shang-Miao Chang [Taïwan] ; Ching-Lung Liu [Taïwan] ; Hsu-Tah Kuo [Taïwan] ; Pei-Jan Chen [Taïwan] ; Chun Ming Lee [Taïwan] ; Fung-J. Lin [Taïwan] ; Ching-Chi Lin [Taïwan] ; Chao-Hsien Lee [Taïwan] ; Yen-Ta Lu [Taïwan]Source :
- The Journal of Emergency Medicine [ 0736-4679 ] ; 2005.
Abstract
To differentiate severe acute respiratory syndrome (SARS) from non-SARS illness, we retrospectively compared 53 patients with probable SARS and 31 patients with non-SARS who were admitted to Mackay Memorial Hospital from April 27 to June 16, 2003. Fever (> 38°C) was the earliest symptom (50/53 SARS vs. 5/31 non-SARS,
Url:
DOI: 10.1016/j.jemermed.2004.11.022
PubMed: 15837019
PubMed Central: 7135563
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>To differentiate severe acute respiratory syndrome (SARS) from non-SARS illness, we retrospectively compared 53 patients with probable SARS and 31 patients with non-SARS who were admitted to Mackay Memorial Hospital from April 27 to June 16, 2003. Fever (> 38°C) was the earliest symptom (50/53 SARS vs. 5/31 non-SARS, <italic>p</italic>
< 0.0001), preceding cough by a mean of 4.5 days. The initial chest X-ray study was normal in 22/53 SARS cases versus 5/31 non-SARS cases. SARS patients with an initially normal chest X-ray study developed infiltrates at a mean of 5 ± 3.44 days after onset of fever (21/22 SARS vs. 0/5 non-SARS). Rapid radiographic progression of unifocal involvement to multifocal infiltrates was seen in 22 of 24 SARS vs. 0 of 26 non-SARS patients (<italic>p</italic>
< 0.0001). Pleural effusion was not present in any SARS patients but was seen in 6 of 26 non-SARS cases (<italic>p</italic>
< 0.0001). Initial lymphopenia, thrombocytopenia, and elevated lactate dehydrogenase were all more common in SARS than non-SARS (<italic>p</italic>
< 0.0001). They may help differentiate SARS from non-SARS if a reliable and rapid diagnostic test is not available.</p>
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