Thrombocytopenia in patients with severe acute respiratory syndrome (review).
Identifieur interne : 004578 ( Main/Exploration ); précédent : 004577; suivant : 004579Thrombocytopenia in patients with severe acute respiratory syndrome (review).
Auteurs : Mo Yang [Hong Kong] ; Margaret H L. Ng ; Chi Kong LiSource :
- Hematology (Amsterdam, Netherlands) [ 1024-5332 ] ; 2005.
Descripteurs français
- KwdFr :
- Cellules souches hématopoïétiques (immunologie), Cellules souches hématopoïétiques (virologie), Humains, Lymphopénie (immunologie), Lymphopénie (virologie), Lymphopénie (étiologie), Numération des lymphocytes, Purpura thrombopénique idiopathique (immunologie), Purpura thrombopénique idiopathique (virologie), Purpura thrombopénique idiopathique (étiologie), Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (immunologie), Virus du SRAS (immunologie).
- MESH :
- immunologie : Cellules souches hématopoïétiques, Lymphopénie, Purpura thrombopénique idiopathique, Syndrome respiratoire aigu sévère, Virus du SRAS.
- virologie : Cellules souches hématopoïétiques, Lymphopénie, Purpura thrombopénique idiopathique.
- étiologie : Lymphopénie, Purpura thrombopénique idiopathique.
- Humains, Numération des lymphocytes, Syndrome respiratoire aigu sévère.
English descriptors
- KwdEn :
- Hematopoietic Stem Cells (immunology), Hematopoietic Stem Cells (virology), Humans, Lymphocyte Count, Lymphopenia (etiology), Lymphopenia (immunology), Lymphopenia (virology), Purpura, Thrombocytopenic, Idiopathic (etiology), Purpura, Thrombocytopenic, Idiopathic (immunology), Purpura, Thrombocytopenic, Idiopathic (virology), SARS Virus (immunology), Severe Acute Respiratory Syndrome (complications), Severe Acute Respiratory Syndrome (immunology).
- MESH :
- complications : Severe Acute Respiratory Syndrome.
- etiology : Lymphopenia, Purpura, Thrombocytopenic, Idiopathic.
- immunology : Hematopoietic Stem Cells, Lymphopenia, Purpura, Thrombocytopenic, Idiopathic, SARS Virus, Severe Acute Respiratory Syndrome.
- virology : Hematopoietic Stem Cells, Lymphopenia, Purpura, Thrombocytopenic, Idiopathic.
- Humans, Lymphocyte Count.
Abstract
Severe Acute Respiratory Syndrome (SARS) has been recognized as a new human infectious disease caused by a novel coronavirus (SARS-CoV). Hematological changes in patients with SARS were common, including notably lymphopenia and thrombocytopenia. While the former is the result of decreases in CD4+ or CD8+ T-lymphocytes related to the onset of disease or use of glucocorticoids, the latter may involve a number of potential mechanisms. Although the development of autoimmune antibodies or immune complexes triggered by viral infection may play a significant role in inducing thrombocytopenia, SARS-CoV may also directly infect hematopoietic stem/progenitor cells, megakaryocytes and platelets inducing their growth inhibition and apoptosis. Moreover, the increased consumption of platelets and/or the decreased production of platelets in the damaged lungs are a potential alternative mechanism that can contribute to thrombocytopenia in severe critical pulmonary conditions, which has been rarely revealed and will be discussed.
DOI: 10.1080/10245330400026170
PubMed: 16019455
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 002642
- to stream PubMed, to step Curation: 002642
- to stream PubMed, to step Checkpoint: 002411
- to stream Ncbi, to step Merge: 001058
- to stream Ncbi, to step Curation: 001058
- to stream Ncbi, to step Checkpoint: 001058
- to stream Main, to step Merge: 004814
- to stream Main, to step Curation: 004578
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Thrombocytopenia in patients with severe acute respiratory syndrome (review).</title><author><name sortKey="Yang, Mo" sort="Yang, Mo" uniqKey="Yang M" first="Mo" last="Yang">Mo Yang</name><affiliation wicri:level="4"><nlm:affiliation>Department of Paediatrics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong. yang1091@cuhk.edu.hk</nlm:affiliation><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Paediatrics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Ng, Margaret H L" sort="Ng, Margaret H L" uniqKey="Ng M" first="Margaret H L" last="Ng">Margaret H L. Ng</name></author><author><name sortKey="Li, Chi Kong" sort="Li, Chi Kong" uniqKey="Li C" first="Chi Kong" last="Li">Chi Kong Li</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2005">2005</date><idno type="RBID">pubmed:16019455</idno><idno type="pmid">16019455</idno><idno type="doi">10.1080/10245330400026170</idno><idno type="wicri:Area/PubMed/Corpus">002642</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002642</idno><idno type="wicri:Area/PubMed/Curation">002642</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002642</idno><idno type="wicri:Area/PubMed/Checkpoint">002411</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002411</idno><idno type="wicri:Area/Ncbi/Merge">001058</idno><idno type="wicri:Area/Ncbi/Curation">001058</idno><idno type="wicri:Area/Ncbi/Checkpoint">001058</idno><idno type="wicri:doubleKey">1024-5332:2005:Yang M:thrombocytopenia:in:patients</idno><idno type="wicri:Area/Main/Merge">004814</idno><idno type="wicri:Area/Main/Curation">004578</idno><idno type="wicri:Area/Main/Exploration">004578</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Thrombocytopenia in patients with severe acute respiratory syndrome (review).</title><author><name sortKey="Yang, Mo" sort="Yang, Mo" uniqKey="Yang M" first="Mo" last="Yang">Mo Yang</name><affiliation wicri:level="4"><nlm:affiliation>Department of Paediatrics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong. yang1091@cuhk.edu.hk</nlm:affiliation><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Paediatrics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Ng, Margaret H L" sort="Ng, Margaret H L" uniqKey="Ng M" first="Margaret H L" last="Ng">Margaret H L. Ng</name></author><author><name sortKey="Li, Chi Kong" sort="Li, Chi Kong" uniqKey="Li C" first="Chi Kong" last="Li">Chi Kong Li</name></author></analytic><series><title level="j">Hematology (Amsterdam, Netherlands)</title><idno type="ISSN">1024-5332</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Hematopoietic Stem Cells (immunology)</term><term>Hematopoietic Stem Cells (virology)</term><term>Humans</term><term>Lymphocyte Count</term><term>Lymphopenia (etiology)</term><term>Lymphopenia (immunology)</term><term>Lymphopenia (virology)</term><term>Purpura, Thrombocytopenic, Idiopathic (etiology)</term><term>Purpura, Thrombocytopenic, Idiopathic (immunology)</term><term>Purpura, Thrombocytopenic, Idiopathic (virology)</term><term>SARS Virus (immunology)</term><term>Severe Acute Respiratory Syndrome (complications)</term><term>Severe Acute Respiratory Syndrome (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Cellules souches hématopoïétiques (immunologie)</term><term>Cellules souches hématopoïétiques (virologie)</term><term>Humains</term><term>Lymphopénie (immunologie)</term><term>Lymphopénie (virologie)</term><term>Lymphopénie (étiologie)</term><term>Numération des lymphocytes</term><term>Purpura thrombopénique idiopathique (immunologie)</term><term>Purpura thrombopénique idiopathique (virologie)</term><term>Purpura thrombopénique idiopathique (étiologie)</term><term>Syndrome respiratoire aigu sévère ()</term><term>Syndrome respiratoire aigu sévère (immunologie)</term><term>Virus du SRAS (immunologie)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphopenia</term><term>Purpura, Thrombocytopenic, Idiopathic</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Cellules souches hématopoïétiques</term><term>Lymphopénie</term><term>Purpura thrombopénique idiopathique</term><term>Syndrome respiratoire aigu sévère</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Hematopoietic Stem Cells</term><term>Lymphopenia</term><term>Purpura, Thrombocytopenic, Idiopathic</term><term>SARS Virus</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Cellules souches hématopoïétiques</term><term>Lymphopénie</term><term>Purpura thrombopénique idiopathique</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Hematopoietic Stem Cells</term><term>Lymphopenia</term><term>Purpura, Thrombocytopenic, Idiopathic</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphopénie</term><term>Purpura thrombopénique idiopathique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term><term>Lymphocyte Count</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Numération des lymphocytes</term><term>Syndrome respiratoire aigu sévère</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Severe Acute Respiratory Syndrome (SARS) has been recognized as a new human infectious disease caused by a novel coronavirus (SARS-CoV). Hematological changes in patients with SARS were common, including notably lymphopenia and thrombocytopenia. While the former is the result of decreases in CD4+ or CD8+ T-lymphocytes related to the onset of disease or use of glucocorticoids, the latter may involve a number of potential mechanisms. Although the development of autoimmune antibodies or immune complexes triggered by viral infection may play a significant role in inducing thrombocytopenia, SARS-CoV may also directly infect hematopoietic stem/progenitor cells, megakaryocytes and platelets inducing their growth inhibition and apoptosis. Moreover, the increased consumption of platelets and/or the decreased production of platelets in the damaged lungs are a potential alternative mechanism that can contribute to thrombocytopenia in severe critical pulmonary conditions, which has been rarely revealed and will be discussed.</div></front></TEI><affiliations><list><country><li>Hong Kong</li></country><settlement><li>Sha Tin</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><noCountry><name sortKey="Li, Chi Kong" sort="Li, Chi Kong" uniqKey="Li C" first="Chi Kong" last="Li">Chi Kong Li</name><name sortKey="Ng, Margaret H L" sort="Ng, Margaret H L" uniqKey="Ng M" first="Margaret H L" last="Ng">Margaret H L. Ng</name></noCountry><country name="Hong Kong"><noRegion><name sortKey="Yang, Mo" sort="Yang, Mo" uniqKey="Yang M" first="Mo" last="Yang">Mo Yang</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004578 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004578 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:16019455
|texte= Thrombocytopenia in patients with severe acute respiratory syndrome (review).
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:16019455" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |