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Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus.

Identifieur interne : 003703 ( Main/Exploration ); précédent : 003702; suivant : 003704

Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus.

Auteurs : Victor C. Chu [États-Unis] ; Lisa J. Mcelroy ; Jed M. Aronson ; Trisha J. Oura ; Carole E. Harbison ; Beverley E. Bauman ; Gary R. Whittaker

Source :

RBID : pubmed:17324273

Descripteurs français

English descriptors

Abstract

Coronaviruses are an important cause of infectious diseases in humans, including severe acute respiratory syndrome (SARS), and have the continued potential for emergence from animal species. A major factor in the host range of a coronavirus is its receptor utilization on host cells. In many cases, coronavirus-receptor interactions are well understood. However, a notable exception is the receptor utilization by group 3 coronaviruses, including avian infectious bronchitis virus (IBV). Feline aminopeptidase N (fAPN) serves as a functional receptor for most group 1 coronaviruses including feline infectious peritonitis virus (FIPV), canine coronavirus, transmissible gastroenteritis virus (TGEV), and human coronavirus 229E (HCoV-229E). A recent report has also suggested a role for fAPN during IBV entry (Miguel B, Pharr GT, Wang C: The role of feline aminopeptidase N as a receptor for infectious bronchitis virus. Brief review. Arch Virol 2002, 147:2047-2056.

DOI: 10.1186/1743-422X-4-20
PubMed: 17324273


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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