Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus.
Identifieur interne : 003703 ( Main/Exploration ); précédent : 003702; suivant : 003704Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus.
Auteurs : Victor C. Chu [États-Unis] ; Lisa J. Mcelroy ; Jed M. Aronson ; Trisha J. Oura ; Carole E. Harbison ; Beverley E. Bauman ; Gary R. WhittakerSource :
- Virology journal [ 1743-422X ] ; 2007.
Descripteurs français
- KwdFr :
- MESH :
- croissance et développement : Virus de la bronchite infectieuse.
- physiologie : Récepteurs viraux, Virus de la bronchite infectieuse.
- Animaux, Attachement viral, Chats, Cricetinae, Lignée cellulaire, Poulets.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : CD13 Antigens.
- chemical , physiology : CD13 Antigens, Receptors, Virus.
- growth & development : Infectious bronchitis virus.
- physiology : Infectious bronchitis virus.
- Animals, Cats, Cell Line, Chickens, Cricetinae, Virus Attachment.
Abstract
Coronaviruses are an important cause of infectious diseases in humans, including severe acute respiratory syndrome (SARS), and have the continued potential for emergence from animal species. A major factor in the host range of a coronavirus is its receptor utilization on host cells. In many cases, coronavirus-receptor interactions are well understood. However, a notable exception is the receptor utilization by group 3 coronaviruses, including avian infectious bronchitis virus (IBV). Feline aminopeptidase N (fAPN) serves as a functional receptor for most group 1 coronaviruses including feline infectious peritonitis virus (FIPV), canine coronavirus, transmissible gastroenteritis virus (TGEV), and human coronavirus 229E (HCoV-229E). A recent report has also suggested a role for fAPN during IBV entry (Miguel B, Pharr GT, Wang C: The role of feline aminopeptidase N as a receptor for infectious bronchitis virus. Brief review. Arch Virol 2002, 147:2047-2056.
DOI: 10.1186/1743-422X-4-20
PubMed: 17324273
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Coronaviruses are an important cause of infectious diseases in humans, including severe acute respiratory syndrome (SARS), and have the continued potential for emergence from animal species. A major factor in the host range of a coronavirus is its receptor utilization on host cells. In many cases, coronavirus-receptor interactions are well understood. However, a notable exception is the receptor utilization by group 3 coronaviruses, including avian infectious bronchitis virus (IBV). Feline aminopeptidase N (fAPN) serves as a functional receptor for most group 1 coronaviruses including feline infectious peritonitis virus (FIPV), canine coronavirus, transmissible gastroenteritis virus (TGEV), and human coronavirus 229E (HCoV-229E). A recent report has also suggested a role for fAPN during IBV entry (Miguel B, Pharr GT, Wang C: The role of feline aminopeptidase N as a receptor for infectious bronchitis virus. Brief review. Arch Virol 2002, 147:2047-2056.</div>
</front>
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<name sortKey="Whittaker, Gary R" sort="Whittaker, Gary R" uniqKey="Whittaker G" first="Gary R" last="Whittaker">Gary R. Whittaker</name>
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<country name="États-Unis"><region name="État de New York"><name sortKey="Chu, Victor C" sort="Chu, Victor C" uniqKey="Chu V" first="Victor C" last="Chu">Victor C. Chu</name>
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