SrasV1, Main, Exploration, bibRecord, 002D54

Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human

Identifieur interne : 002D54 ( Main/Exploration ); précédent : 002D53; suivant : 002D55

Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human

Auteurs : Na Ding [République populaire de Chine] ; Nana Wu [République populaire de Chine] ; Qinggang Xu [République populaire de Chine] ; Keping Chen [République populaire de Chine] ; Chiyu Zhang [République populaire de Chine]

Source :

Virus Genes [ 0920-8569 ] ; 2009-12-01.

RBID : ISTEX:D35C909DA80E2D58589F2E2E9E3867495A515C9F

English descriptors

KwdEn :
- Adaptive evolution, Novel A/H1N1 influenza virus, Reassortment, Selective sweep.

Abstract

Abstract: We find that the novel A/H1N1 influenza viruses exhibit very low genetic divergence and suffer strong purifying selection among human population and confirm that they originated from the reassortment of previous triple-reassortant swine influenza viruses including genomic segments from both avian and human lineages with North American and Eurasian swine lineages. The longer phylogenetic branch length to their nearest genetic neighbors indicates that the origin of the novel A/H1N1 is unlikely to be a very recent event. Seventy-six new unique mutations are found to be monomorphically fixed in the novel A/H1N1 virus lineages, suggesting a role of selective sweep in the early evolution of this virus.

Url:

https://api.istex.fr/ark:/67375/VQC-J6XCVFVT-4/fulltext.pdf

DOI: 10.1007/s11262-009-0393-7

Affiliations:

République populaire de Chine

Links toward previous steps (curation, corpus...)

to stream Istex, to step Corpus: 000729
to stream Istex, to step Curation: 000729
to stream Istex, to step Checkpoint: 000D17
to stream Main, to step Merge: 002E08
to stream Main, to step Curation: 002D54

Le document en format XML

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<author><name sortKey="Xu, Qinggang" sort="Xu, Qinggang" uniqKey="Xu Q" first="Qinggang" last="Xu">Qinggang Xu</name>
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<author><name sortKey="Chen, Keping" sort="Chen, Keping" uniqKey="Chen K" first="Keping" last="Chen">Keping Chen</name>
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<front><div type="abstract" xml:lang="en">Abstract: We find that the novel A/H1N1 influenza viruses exhibit very low genetic divergence and suffer strong purifying selection among human population and confirm that they originated from the reassortment of previous triple-reassortant swine influenza viruses including genomic segments from both avian and human lineages with North American and Eurasian swine lineages. The longer phylogenetic branch length to their nearest genetic neighbors indicates that the origin of the novel A/H1N1 is unlikely to be a very recent event. Seventy-six new unique mutations are found to be monomorphically fixed in the novel A/H1N1 virus lineages, suggesting a role of selective sweep in the early evolution of this virus.</div>
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Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human

Molecular evolution of novel swine-origin A/H1N1 influenza viruses among and before human

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri