Identification of NCAM that interacts with the PHE-CoV spike protein.
Identifieur interne : 002528 ( Main/Exploration ); précédent : 002527; suivant : 002529Identification of NCAM that interacts with the PHE-CoV spike protein.
Auteurs : Wei Gao [République populaire de Chine] ; Wenqi He ; Kui Zhao ; Huijun Lu ; Wenzhi Ren ; Chongtao Du ; Keyan Chen ; Yungang Lan ; Deguang Song ; Feng GaoSource :
- Virology journal [ 1743-422X ] ; 2010.
Descripteurs français
- KwdFr :
- Animaux, Banque de peptides, Coronavirus (pathogénicité), Extinction de l'expression des gènes, Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (métabolisme), Immunoprécipitation, Interactions hôte-pathogène, Liaison aux protéines, Lignée cellulaire, Molécules d'adhérence cellulaire neurales (métabolisme), Petit ARN interférent (génétique), Petit ARN interférent (métabolisme), Podoviridae (génétique), Protéines de l'enveloppe virale (métabolisme), Souris.
- MESH :
- génétique : Petit ARN interférent, Podoviridae.
- métabolisme : Glycoprotéines membranaires, Molécules d'adhérence cellulaire neurales, Petit ARN interférent, Protéines de l'enveloppe virale.
- pathogénicité : Coronavirus.
- Animaux, Banque de peptides, Extinction de l'expression des gènes, Glycoprotéine de spicule des coronavirus, Immunoprécipitation, Interactions hôte-pathogène, Liaison aux protéines, Lignée cellulaire, Souris.
English descriptors
- KwdEn :
- Animals, Cell Line, Coronavirus (pathogenicity), Gene Silencing, Host-Pathogen Interactions, Immunoprecipitation, Membrane Glycoproteins (metabolism), Mice, Neural Cell Adhesion Molecules (metabolism), Peptide Library, Podoviridae (genetics), Protein Binding, RNA, Small Interfering (genetics), RNA, Small Interfering (metabolism), Spike Glycoprotein, Coronavirus, Viral Envelope Proteins (metabolism).
- MESH :
- chemical , genetics : RNA, Small Interfering.
- chemical , metabolism : Membrane Glycoproteins, Neural Cell Adhesion Molecules, RNA, Small Interfering, Viral Envelope Proteins.
- genetics : Podoviridae.
- pathogenicity : Coronavirus.
- Animals, Cell Line, Gene Silencing, Host-Pathogen Interactions, Immunoprecipitation, Mice, Peptide Library, Protein Binding, Spike Glycoprotein, Coronavirus.
Abstract
The spike proteins of coronaviruses associate with cellular molecules to mediate infection of their target cells. The characterization of cellular proteins required for virus infection is essential for understanding viral life cycles and may provide cellular targets for antiviral therapies.
DOI: 10.1186/1743-422X-7-254
PubMed: 20863409
Affiliations:
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Le document en format XML
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