Development of reflective biosensor using fabrication of functionalized photonic nanocrystals.
Identifieur interne : 002128 ( Main/Exploration ); précédent : 002127; suivant : 002129Development of reflective biosensor using fabrication of functionalized photonic nanocrystals.
Auteurs : Tae Jung Park [Corée du Sud] ; Seung-Kon Lee ; Seung Min Yoo ; Seung-Man Yang ; Sang Yup LeeSource :
- Journal of nanoscience and nanotechnology [ 1533-4880 ] ; 2011.
Descripteurs français
- KwdFr :
- ADN bactérien (génétique), ADN bactérien (isolement et purification), Acinetobacter baumannii (génétique), Anticorps antibactériens (métabolisme), Colloïdes (), Fusobacterium necrophorum (génétique), Hybridation d'acides nucléiques, Microscopie électronique à balayage, Nanoparticules (), Phénomènes optiques, Protéines de l'enveloppe virale (isolement et purification), Protéines de l'enveloppe virale (métabolisme), Silice (), Techniques de biocapteur (), Virus du SRAS (), Virus du SRAS (métabolisme).
- MESH :
- génétique : ADN bactérien, Acinetobacter baumannii, Fusobacterium necrophorum.
- isolement et purification : ADN bactérien, Protéines de l'enveloppe virale.
- métabolisme : Anticorps antibactériens, Protéines de l'enveloppe virale, Virus du SRAS.
- Colloïdes, Hybridation d'acides nucléiques, Microscopie électronique à balayage, Nanoparticules, Phénomènes optiques, Silice, Techniques de biocapteur, Virus du SRAS.
English descriptors
- KwdEn :
- Acinetobacter baumannii (genetics), Antibodies, Bacterial (metabolism), Biosensing Techniques (methods), Colloids (chemistry), DNA, Bacterial (genetics), DNA, Bacterial (isolation & purification), Fusobacterium necrophorum (genetics), Microscopy, Electron, Scanning, Nanoparticles (chemistry), Nucleic Acid Hybridization, Optical Phenomena, SARS Virus (chemistry), SARS Virus (metabolism), Silicon Dioxide (chemistry), Viral Envelope Proteins (isolation & purification), Viral Envelope Proteins (metabolism).
- MESH :
- chemical , chemistry : Colloids, Silicon Dioxide.
- chemical , genetics : DNA, Bacterial.
- chemical , isolation & purification : DNA, Bacterial, Viral Envelope Proteins.
- chemical , metabolism : Antibodies, Bacterial, Viral Envelope Proteins.
- chemistry : Nanoparticles, SARS Virus.
- genetics : Acinetobacter baumannii, Fusobacterium necrophorum.
- metabolism : SARS Virus.
- methods : Biosensing Techniques.
- Microscopy, Electron, Scanning, Nucleic Acid Hybridization, Optical Phenomena.
Abstract
Photonic crystals (PCs) are periodic dielectric structures that have a band-gap that forbids propagation of a certain range of wavelengths of light. This property enables control of light with remarkable facility by modification of the band-gaps and produce effects that are impossible with conventional optics. Using chemically functionalized PCs, where the chemical functional group consists of amine and carboxyl group, in conjunction with a biomolecular probe material, the detection of pathogens and viral disease is possible, indicated by the shift in wavelength signal. Moreover, this system using the bioinspired PCs allows specific target detection in biosensor chip fields through control of the PCs. In this study, we demonstrated that two bacterial pathogens (Fusobacterium necrophorum and Acinetobacter baumannii) causing sepsis were detected by DNA-probe hybridization and a severe acute respiratory syndrome coronavirus was detected by antigen-antibody interaction using the functional PCs. Optical readout with the integrated sensor detecting the signals from PCs, allows for low cost and robust readout of resonance peak shift. This biosensor system using the functional PCs on the photonic crystal-fabricated chip can efficiently and effectively detect various targets, and be easily prepared with high productivity and economic property.
DOI: 10.1166/jnn.2011.3269
PubMed: 21446513
Affiliations:
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Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acinetobacter baumannii (genetics)</term>
<term>Antibodies, Bacterial (metabolism)</term>
<term>Biosensing Techniques (methods)</term>
<term>Colloids (chemistry)</term>
<term>DNA, Bacterial (genetics)</term>
<term>DNA, Bacterial (isolation & purification)</term>
<term>Fusobacterium necrophorum (genetics)</term>
<term>Microscopy, Electron, Scanning</term>
<term>Nanoparticles (chemistry)</term>
<term>Nucleic Acid Hybridization</term>
<term>Optical Phenomena</term>
<term>SARS Virus (chemistry)</term>
<term>SARS Virus (metabolism)</term>
<term>Silicon Dioxide (chemistry)</term>
<term>Viral Envelope Proteins (isolation & purification)</term>
<term>Viral Envelope Proteins (metabolism)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>ADN bactérien (génétique)</term>
<term>ADN bactérien (isolement et purification)</term>
<term>Acinetobacter baumannii (génétique)</term>
<term>Anticorps antibactériens (métabolisme)</term>
<term>Colloïdes ()</term>
<term>Fusobacterium necrophorum (génétique)</term>
<term>Hybridation d'acides nucléiques</term>
<term>Microscopie électronique à balayage</term>
<term>Nanoparticules ()</term>
<term>Phénomènes optiques</term>
<term>Protéines de l'enveloppe virale (isolement et purification)</term>
<term>Protéines de l'enveloppe virale (métabolisme)</term>
<term>Silice ()</term>
<term>Techniques de biocapteur ()</term>
<term>Virus du SRAS ()</term>
<term>Virus du SRAS (métabolisme)</term>
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<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Colloids</term>
<term>Silicon Dioxide</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>DNA, Bacterial</term>
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<keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>DNA, Bacterial</term>
<term>Viral Envelope Proteins</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Antibodies, Bacterial</term>
<term>Viral Envelope Proteins</term>
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<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Nanoparticles</term>
<term>SARS Virus</term>
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<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Acinetobacter baumannii</term>
<term>Fusobacterium necrophorum</term>
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<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ADN bactérien</term>
<term>Acinetobacter baumannii</term>
<term>Fusobacterium necrophorum</term>
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<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>ADN bactérien</term>
<term>Protéines de l'enveloppe virale</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Biosensing Techniques</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Anticorps antibactériens</term>
<term>Protéines de l'enveloppe virale</term>
<term>Virus du SRAS</term>
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<keywords scheme="MESH" xml:lang="en"><term>Microscopy, Electron, Scanning</term>
<term>Nucleic Acid Hybridization</term>
<term>Optical Phenomena</term>
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<term>Hybridation d'acides nucléiques</term>
<term>Microscopie électronique à balayage</term>
<term>Nanoparticules</term>
<term>Phénomènes optiques</term>
<term>Silice</term>
<term>Techniques de biocapteur</term>
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<front><div type="abstract" xml:lang="en">Photonic crystals (PCs) are periodic dielectric structures that have a band-gap that forbids propagation of a certain range of wavelengths of light. This property enables control of light with remarkable facility by modification of the band-gaps and produce effects that are impossible with conventional optics. Using chemically functionalized PCs, where the chemical functional group consists of amine and carboxyl group, in conjunction with a biomolecular probe material, the detection of pathogens and viral disease is possible, indicated by the shift in wavelength signal. Moreover, this system using the bioinspired PCs allows specific target detection in biosensor chip fields through control of the PCs. In this study, we demonstrated that two bacterial pathogens (Fusobacterium necrophorum and Acinetobacter baumannii) causing sepsis were detected by DNA-probe hybridization and a severe acute respiratory syndrome coronavirus was detected by antigen-antibody interaction using the functional PCs. Optical readout with the integrated sensor detecting the signals from PCs, allows for low cost and robust readout of resonance peak shift. This biosensor system using the functional PCs on the photonic crystal-fabricated chip can efficiently and effectively detect various targets, and be easily prepared with high productivity and economic property.</div>
</front>
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<tree><noCountry><name sortKey="Lee, Sang Yup" sort="Lee, Sang Yup" uniqKey="Lee S" first="Sang Yup" last="Lee">Sang Yup Lee</name>
<name sortKey="Lee, Seung Kon" sort="Lee, Seung Kon" uniqKey="Lee S" first="Seung-Kon" last="Lee">Seung-Kon Lee</name>
<name sortKey="Yang, Seung Man" sort="Yang, Seung Man" uniqKey="Yang S" first="Seung-Man" last="Yang">Seung-Man Yang</name>
<name sortKey="Yoo, Seung Min" sort="Yoo, Seung Min" uniqKey="Yoo S" first="Seung Min" last="Yoo">Seung Min Yoo</name>
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<country name="Corée du Sud"><noRegion><name sortKey="Park, Tae Jung" sort="Park, Tae Jung" uniqKey="Park T" first="Tae Jung" last="Park">Tae Jung Park</name>
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