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Functional protein microarray as molecular decathlete: A versatile player in clinical proteomics

Identifieur interne : 001E85 ( Main/Exploration ); précédent : 001E84; suivant : 001E86

Functional protein microarray as molecular decathlete: A versatile player in clinical proteomics

Auteurs : Heng Zhu [États-Unis] ; Eric Cox [États-Unis] ; Jiang Qian [États-Unis]

Source :

RBID : ISTEX:B6E642695C36FC31B3E108AF04A6FA9AC39D43D0

English descriptors

Abstract

Functional protein microarrays were developed as a high‐throughput tool to overcome the limitations of DNA microarrays and to provide a versatile platform for protein functional analyses. Recent years have witnessed tremendous growth in the use of protein microarrays, particularly functional protein microarrays, to address important questions in the field of clinical proteomics. In this review, we will summarize some of the most innovative and exciting recent applications of protein microarrays in clinical proteomics, including biomarker identification, pathogen–host interactions, and cancer biology.

Url:
DOI: 10.1002/prca.201200041


Affiliations:


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<div type="abstract">Functional protein microarrays were developed as a high‐throughput tool to overcome the limitations of DNA microarrays and to provide a versatile platform for protein functional analyses. Recent years have witnessed tremendous growth in the use of protein microarrays, particularly functional protein microarrays, to address important questions in the field of clinical proteomics. In this review, we will summarize some of the most innovative and exciting recent applications of protein microarrays in clinical proteomics, including biomarker identification, pathogen–host interactions, and cancer biology.</div>
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