VIRsiRNApred: a web server for predicting inhibition efficacy of siRNAs targeting human viruses.
Identifieur interne : 001818 ( Main/Exploration ); précédent : 001817; suivant : 001819VIRsiRNApred: a web server for predicting inhibition efficacy of siRNAs targeting human viruses.
Auteurs : Abid Qureshi ; Nishant Thakur ; Manoj Kumar [Inde]Source :
- Journal of translational medicine [ 1479-5876 ] ; 2013.
Descripteurs français
- KwdFr :
- Algorithmes, Bases de données génétiques, Conformation d'acide nucléique, Humains, Internet, Orthomyxoviridae (génétique), Orthomyxoviridae (isolement et purification), Petit ARN interférent (), Petit ARN interférent (génétique), Thermodynamique, VIH (Virus de l'Immunodéficience Humaine) (génétique), VIH (Virus de l'Immunodéficience Humaine) (isolement et purification), Virus de l'hépatite (génétique), Virus de l'hépatite (isolement et purification), Virus du SRAS (génétique), Virus du SRAS (isolement et purification).
- MESH :
- génétique : Orthomyxoviridae, Petit ARN interférent, VIH (Virus de l'Immunodéficience Humaine), Virus de l'hépatite, Virus du SRAS.
- isolement et purification : Orthomyxoviridae, VIH (Virus de l'Immunodéficience Humaine), Virus de l'hépatite, Virus du SRAS.
- Algorithmes, Bases de données génétiques, Conformation d'acide nucléique, Humains, Internet, Petit ARN interférent, Thermodynamique.
English descriptors
- KwdEn :
- Algorithms, Databases, Genetic, HIV (genetics), HIV (isolation & purification), Hepatitis Viruses (genetics), Hepatitis Viruses (isolation & purification), Humans, Internet, Nucleic Acid Conformation, Orthomyxoviridae (genetics), Orthomyxoviridae (isolation & purification), RNA, Small Interfering (chemistry), RNA, Small Interfering (genetics), SARS Virus (genetics), SARS Virus (isolation & purification), Thermodynamics.
- MESH :
- chemical , chemistry : RNA, Small Interfering.
- genetics : HIV, Hepatitis Viruses, Orthomyxoviridae, RNA, Small Interfering, SARS Virus.
- isolation & purification : HIV, Hepatitis Viruses, Orthomyxoviridae, SARS Virus.
- Algorithms, Databases, Genetic, Humans, Internet, Nucleic Acid Conformation, Thermodynamics.
Abstract
Selection of effective viral siRNA is an indispensable step in the development of siRNA based antiviral therapeutics. Despite immense potential, a viral siRNA efficacy prediction algorithm is still not available. Moreover, performances of the existing general mammalian siRNA efficacy predictors are not satisfactory for viral siRNAs. Therefore, we have developed "VIRsiRNApred" a support vector machine (SVM) based method for predicting the efficacy of viral siRNA.
DOI: 10.1186/1479-5876-11-305
PubMed: 24330765
Affiliations:
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Le document en format XML
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Microbial Technology, Council of Scientific and Industrial Research, Sector 39-A, Chandigarh 160036</wicri:regionArea><wicri:noRegion>Chandigarh 160036</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of translational medicine</title><idno type="eISSN">1479-5876</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Algorithms</term><term>Databases, Genetic</term><term>HIV (genetics)</term><term>HIV (isolation & purification)</term><term>Hepatitis Viruses (genetics)</term><term>Hepatitis Viruses (isolation & purification)</term><term>Humans</term><term>Internet</term><term>Nucleic Acid Conformation</term><term>Orthomyxoviridae (genetics)</term><term>Orthomyxoviridae (isolation & purification)</term><term>RNA, Small Interfering (chemistry)</term><term>RNA, Small Interfering (genetics)</term><term>SARS Virus 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scheme="MESH" qualifier="genetics" xml:lang="en"><term>HIV</term><term>Hepatitis Viruses</term><term>Orthomyxoviridae</term><term>RNA, Small Interfering</term><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Orthomyxoviridae</term><term>Petit ARN interférent</term><term>VIH (Virus de l'Immunodéficience Humaine)</term><term>Virus de l'hépatite</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>HIV</term><term>Hepatitis Viruses</term><term>Orthomyxoviridae</term><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Orthomyxoviridae</term><term>VIH (Virus de l'Immunodéficience Humaine)</term><term>Virus de l'hépatite</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Algorithms</term><term>Databases, Genetic</term><term>Humans</term><term>Internet</term><term>Nucleic Acid Conformation</term><term>Thermodynamics</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Algorithmes</term><term>Bases de données génétiques</term><term>Conformation d'acide nucléique</term><term>Humains</term><term>Internet</term><term>Petit ARN interférent</term><term>Thermodynamique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Selection of effective viral siRNA is an indispensable step in the development of siRNA based antiviral therapeutics. Despite immense potential, a viral siRNA efficacy prediction algorithm is still not available. Moreover, performances of the existing general mammalian siRNA efficacy predictors are not satisfactory for viral siRNAs. Therefore, we have developed "VIRsiRNApred" a support vector machine (SVM) based method for predicting the efficacy of viral siRNA.</div></front></TEI><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Qureshi, Abid" sort="Qureshi, Abid" uniqKey="Qureshi A" first="Abid" last="Qureshi">Abid Qureshi</name><name sortKey="Thakur, Nishant" sort="Thakur, Nishant" uniqKey="Thakur N" first="Nishant" last="Thakur">Nishant Thakur</name></noCountry><country name="Inde"><noRegion><name sortKey="Kumar, Manoj" sort="Kumar, Manoj" uniqKey="Kumar M" first="Manoj" last="Kumar">Manoj Kumar</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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