Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus.
Identifieur interne : 001703 ( Main/Exploration ); précédent : 001702; suivant : 001704Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus.
Auteurs : Ming Shum Yip ; Nancy Hiu Lan Leung ; Chung Yan Cheung ; Ping Hung Li ; Horace Hok Yeung Lee ; Marc Daëron ; Joseph Sriyal Malik Peiris ; Roberto Bruzzone [Hong Kong] ; Martial JaumeSource :
- Virology journal [ 1743-422X ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- immunologie : Anticorps antiviraux.
- physiologie : Virus du SRAS.
- virologie : Macrophages.
- Cellules cultivées, Endocytose, Humains, Microscopie de fluorescence, Réaction de polymérisation en chaine en temps réel.
English descriptors
- KwdEn :
- MESH :
- chemical , immunology : Antibodies, Viral.
- physiology : SARS Virus.
- virology : Macrophages.
- Cells, Cultured, Endocytosis, Humans, Microscopy, Fluorescence, Real-Time Polymerase Chain Reaction.
- mix :
Abstract
Public health risks associated to infection by human coronaviruses remain considerable and vaccination is a key option for preventing the resurgence of severe acute respiratory syndrome coronavirus (SARS-CoV). We have previously reported that antibodies elicited by a SARS-CoV vaccine candidate based on recombinant, full-length SARS-CoV Spike-protein trimers, trigger infection of immune cell lines. These observations prompted us to investigate the molecular mechanisms and responses to antibody-mediated infection in human macrophages.
Url:
DOI: 10.1186/1743-422X-11-82
PubMed: 24885320
Affiliations:
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Le document en format XML
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sortKey="Jaume, Martial" sort="Jaume, Martial" uniqKey="Jaume M" first="Martial" last="Jaume">Martial Jaume</name></author></analytic><series><title level="j">Virology journal</title><idno type="eISSN">1743-422X</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibodies, Viral (immunology)</term><term>Cells, Cultured</term><term>Endocytosis</term><term>Humans</term><term>Macrophages (virology)</term><term>Microscopy, Fluorescence</term><term>Real-Time Polymerase Chain Reaction</term><term>SARS Virus (physiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Anticorps antiviraux (immunologie)</term><term>Cellules cultivées</term><term>Endocytose</term><term>Humains</term><term>Macrophages (virologie)</term><term>Microscopie de fluorescence</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Virus du SRAS (physiologie)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies, Viral</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Anticorps antiviraux</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Macrophages</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Macrophages</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cells, Cultured</term><term>Endocytosis</term><term>Humans</term><term>Microscopy, Fluorescence</term><term>Real-Time Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Cellules cultivées</term><term>Endocytose</term><term>Humains</term><term>Microscopie de 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We have previously reported that antibodies elicited by a SARS-CoV vaccine candidate based on recombinant, full-length SARS-CoV Spike-protein trimers, trigger infection of immune cell lines. These observations prompted us to investigate the molecular mechanisms and responses to antibody-mediated infection in human macrophages.</div></front></TEI><affiliations><list><country><li>Hong Kong</li></country></list><tree><noCountry><name sortKey="Cheung, Chung Yan" sort="Cheung, Chung Yan" uniqKey="Cheung C" first="Chung Yan" last="Cheung">Chung Yan Cheung</name><name sortKey="Daeron, Marc" sort="Daeron, Marc" uniqKey="Daeron M" first="Marc" last="Daëron">Marc Daëron</name><name sortKey="Jaume, Martial" sort="Jaume, Martial" uniqKey="Jaume M" first="Martial" last="Jaume">Martial Jaume</name><name sortKey="Lee, Horace Hok Yeung" sort="Lee, Horace Hok Yeung" uniqKey="Lee H" first="Horace Hok Yeung" last="Lee">Horace Hok Yeung Lee</name><name sortKey="Leung, Nancy Hiu Lan" sort="Leung, Nancy Hiu Lan" uniqKey="Leung N" first="Nancy Hiu Lan" last="Leung">Nancy Hiu Lan Leung</name><name sortKey="Li, Ping Hung" sort="Li, Ping Hung" uniqKey="Li P" first="Ping Hung" last="Li">Ping Hung Li</name><name sortKey="Peiris, Joseph Sriyal Malik" sort="Peiris, Joseph Sriyal Malik" uniqKey="Peiris J" first="Joseph Sriyal Malik" last="Peiris">Joseph Sriyal Malik Peiris</name><name sortKey="Yip, Ming Shum" sort="Yip, Ming Shum" uniqKey="Yip M" first="Ming Shum" last="Yip">Ming Shum Yip</name></noCountry><country name="Hong Kong"><noRegion><name sortKey="Bruzzone, Roberto" sort="Bruzzone, Roberto" uniqKey="Bruzzone R" first="Roberto" last="Bruzzone">Roberto Bruzzone</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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