The structure and functions of coronavirus genomic 3′ and 5′ ends
Identifieur interne : 001214 ( Main/Exploration ); précédent : 001213; suivant : 001215The structure and functions of coronavirus genomic 3′ and 5′ ends
Auteurs : Dong Yang [États-Unis] ; Julian L. Leibowitz [États-Unis]Source :
- Virus Research [ 0168-1702 ] ; 2015.
Descripteurs français
- KwdFr :
- ARN viral (), ARN viral (génétique), ARN viral (métabolisme), Animaux, Conformation d'acide nucléique, Coronavirus (génétique), Coronavirus (physiologie), Génome viral, Humains, Interactions hôte-pathogène, Modèles biologiques, Protéines de liaison à l'ARN (métabolisme), Régions 3' non traduites, Régions 5' non traduites, Régions promotrices (génétique), Réplication virale, Séquence conservée, Transcription génétique.
- MESH :
- génétique : ARN viral, Coronavirus.
- métabolisme : ARN viral, Protéines de liaison à l'ARN.
- physiologie : Coronavirus.
- ARN viral, Animaux, Conformation d'acide nucléique, Génome viral, Humains, Interactions hôte-pathogène, Modèles biologiques, Régions 3' non traduites, Régions 5' non traduites, Régions promotrices (génétique), Réplication virale, Séquence conservée, Transcription génétique.
English descriptors
- KwdEn :
- 3' Untranslated Regions, 5' Untranslated Regions, Animals, Conserved Sequence, Coronavirus (genetics), Coronavirus (physiology), Genome, Viral, Host-Pathogen Interactions, Humans, Models, Biological, Nucleic Acid Conformation, Promoter Regions, Genetic, RNA, Viral (chemistry), RNA, Viral (genetics), RNA, Viral (metabolism), RNA-Binding Proteins (metabolism), Transcription, Genetic, Virus Replication.
- MESH :
- chemical , chemistry : RNA, Viral.
- chemical , genetics : RNA, Viral.
- chemical , metabolism : RNA, Viral, RNA-Binding Proteins.
- chemical : 3' Untranslated Regions, 5' Untranslated Regions.
- genetics : Coronavirus.
- physiology : Coronavirus.
- Animals, Conserved Sequence, Genome, Viral, Host-Pathogen Interactions, Humans, Models, Biological, Nucleic Acid Conformation, Promoter Regions, Genetic, Transcription, Genetic, Virus Replication.
Abstract
Models of conserved 5′ and 3′ betacoronavirus The 5′ All 3′ A putative molecular switch is present in the coronavirus 3′UTR. Proteins interacting with these
Url:
DOI: 10.1016/j.virusres.2015.02.025
PubMed: 25736566
PubMed Central: 4476908
Affiliations:
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Le document en format XML
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<series><title level="j">Virus Research</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>3' Untranslated Regions</term>
<term>5' Untranslated Regions</term>
<term>Animals</term>
<term>Conserved Sequence</term>
<term>Coronavirus (genetics)</term>
<term>Coronavirus (physiology)</term>
<term>Genome, Viral</term>
<term>Host-Pathogen Interactions</term>
<term>Humans</term>
<term>Models, Biological</term>
<term>Nucleic Acid Conformation</term>
<term>Promoter Regions, Genetic</term>
<term>RNA, Viral (chemistry)</term>
<term>RNA, Viral (genetics)</term>
<term>RNA, Viral (metabolism)</term>
<term>RNA-Binding Proteins (metabolism)</term>
<term>Transcription, Genetic</term>
<term>Virus Replication</term>
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<term>ARN viral (génétique)</term>
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<term>Conformation d'acide nucléique</term>
<term>Coronavirus (génétique)</term>
<term>Coronavirus (physiologie)</term>
<term>Génome viral</term>
<term>Humains</term>
<term>Interactions hôte-pathogène</term>
<term>Modèles biologiques</term>
<term>Protéines de liaison à l'ARN (métabolisme)</term>
<term>Régions 3' non traduites</term>
<term>Régions 5' non traduites</term>
<term>Régions promotrices (génétique)</term>
<term>Réplication virale</term>
<term>Séquence conservée</term>
<term>Transcription génétique</term>
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<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>RNA, Viral</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>RNA, Viral</term>
<term>RNA-Binding Proteins</term>
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<keywords scheme="MESH" type="chemical" xml:lang="en"><term>3' Untranslated Regions</term>
<term>5' Untranslated Regions</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term>
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<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ARN viral</term>
<term>Coronavirus</term>
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<term>Protéines de liaison à l'ARN</term>
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</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Coronavirus</term>
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<term>Conserved Sequence</term>
<term>Genome, Viral</term>
<term>Host-Pathogen Interactions</term>
<term>Humans</term>
<term>Models, Biological</term>
<term>Nucleic Acid Conformation</term>
<term>Promoter Regions, Genetic</term>
<term>Transcription, Genetic</term>
<term>Virus Replication</term>
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<term>Régions 5' non traduites</term>
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<front><div type="abstract" xml:lang="en"><title>Highlights</title>
<p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label>
<p id="par0005">Models of conserved 5′ and 3′ betacoronavirus <italic>cis</italic>
-acting RNA secondary structures are presented.</p>
</list-item>
<list-item id="lsti0010"><label>•</label>
<p id="par0010">The 5′ <italic>cis</italic>
-acting sequences required for coronavirus replication extend into the first open reading frame.</p>
</list-item>
<list-item id="lsti0015"><label>•</label>
<p id="par0015">All 3′ <italic>cis</italic>
-acting sequences required for coronavirus replication are contained in the 3′UTR.</p>
</list-item>
<list-item id="lsti0020"><label>•</label>
<p id="par0020">A putative molecular switch is present in the coronavirus 3′UTR.</p>
</list-item>
<list-item id="lsti0025"><label>•</label>
<p id="par0025">Proteins interacting with these <italic>cis</italic>
-acting regions are reviewed.</p>
</list-item>
</list>
</p>
</div>
</front>
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</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Tennessee</li>
<li>Texas</li>
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<tree><country name="États-Unis"><region name="Tennessee"><name sortKey="Yang, Dong" sort="Yang, Dong" uniqKey="Yang D" first="Dong" last="Yang">Dong Yang</name>
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<name sortKey="Leibowitz, Julian L" sort="Leibowitz, Julian L" uniqKey="Leibowitz J" first="Julian L." last="Leibowitz">Julian L. Leibowitz</name>
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