The structure and functions of coronavirus genomic 3′ and 5′ ends
Identifieur interne : 001214 ( Main/Exploration ); précédent : 001213; suivant : 001215The structure and functions of coronavirus genomic 3′ and 5′ ends
Auteurs : Dong Yang [États-Unis] ; Julian L. Leibowitz [États-Unis]Source :
- Virus Research [ 0168-1702 ] ; 2015.
Descripteurs français
- KwdFr :
- ARN viral (), ARN viral (génétique), ARN viral (métabolisme), Animaux, Conformation d'acide nucléique, Coronavirus (génétique), Coronavirus (physiologie), Génome viral, Humains, Interactions hôte-pathogène, Modèles biologiques, Protéines de liaison à l'ARN (métabolisme), Régions 3' non traduites, Régions 5' non traduites, Régions promotrices (génétique), Réplication virale, Séquence conservée, Transcription génétique.
- MESH :
- génétique : ARN viral, Coronavirus.
- métabolisme : ARN viral, Protéines de liaison à l'ARN.
- physiologie : Coronavirus.
- ARN viral, Animaux, Conformation d'acide nucléique, Génome viral, Humains, Interactions hôte-pathogène, Modèles biologiques, Régions 3' non traduites, Régions 5' non traduites, Régions promotrices (génétique), Réplication virale, Séquence conservée, Transcription génétique.
English descriptors
- KwdEn :
- 3' Untranslated Regions, 5' Untranslated Regions, Animals, Conserved Sequence, Coronavirus (genetics), Coronavirus (physiology), Genome, Viral, Host-Pathogen Interactions, Humans, Models, Biological, Nucleic Acid Conformation, Promoter Regions, Genetic, RNA, Viral (chemistry), RNA, Viral (genetics), RNA, Viral (metabolism), RNA-Binding Proteins (metabolism), Transcription, Genetic, Virus Replication.
- MESH :
- chemical , chemistry : RNA, Viral.
- chemical , genetics : RNA, Viral.
- chemical , metabolism : RNA, Viral, RNA-Binding Proteins.
- chemical : 3' Untranslated Regions, 5' Untranslated Regions.
- genetics : Coronavirus.
- physiology : Coronavirus.
- Animals, Conserved Sequence, Genome, Viral, Host-Pathogen Interactions, Humans, Models, Biological, Nucleic Acid Conformation, Promoter Regions, Genetic, Transcription, Genetic, Virus Replication.
Abstract
Models of conserved 5′ and 3′ betacoronavirus The 5′ All 3′ A putative molecular switch is present in the coronavirus 3′UTR. Proteins interacting with these
Url:
DOI: 10.1016/j.virusres.2015.02.025
PubMed: 25736566
PubMed Central: 4476908
Affiliations:
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Le document en format XML
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Leibowitz</name><affiliation wicri:level="2"><nlm:aff id="aff0010">Department of Microbial Pathogenesis and Immunology, Texas A&M University, College of Medicine, College Station, TX 77843-1114, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbial Pathogenesis and Immunology, Texas A&M University, College of Medicine, College Station, TX 77843-1114</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25736566</idno><idno type="pmc">4476908</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4476908</idno><idno type="RBID">PMC:4476908</idno><idno type="doi">10.1016/j.virusres.2015.02.025</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">001916</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001916</idno><idno type="wicri:Area/Pmc/Curation">001916</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001916</idno><idno type="wicri:Area/Pmc/Checkpoint">000749</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000749</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:25736566</idno><idno type="wicri:Area/PubMed/Corpus">000E50</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E50</idno><idno type="wicri:Area/PubMed/Curation">000E50</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E50</idno><idno type="wicri:Area/PubMed/Checkpoint">000D30</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000D30</idno><idno type="wicri:Area/Ncbi/Merge">002A41</idno><idno type="wicri:Area/Ncbi/Curation">002A41</idno><idno type="wicri:Area/Ncbi/Checkpoint">002A41</idno><idno type="wicri:doubleKey">0168-1702:2015:Yang D:the:structure:and</idno><idno type="wicri:Area/Main/Merge">001216</idno><idno type="wicri:Area/Main/Curation">001214</idno><idno type="wicri:Area/Main/Exploration">001214</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The structure and functions of coronavirus genomic 3′ and 5′ ends</title><author><name sortKey="Yang, Dong" sort="Yang, Dong" uniqKey="Yang D" first="Dong" last="Yang">Dong Yang</name><affiliation wicri:level="2"><nlm:aff id="aff0005">Department of Microbiology, Immunology & Biochemistry, The University of Tennessee Health Science Center College of Medicine, Memphis, TN 38163, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbiology, Immunology & Biochemistry, The University of Tennessee Health Science Center College of Medicine, Memphis, TN 38163</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Leibowitz, Julian L" sort="Leibowitz, Julian L" uniqKey="Leibowitz J" first="Julian L." last="Leibowitz">Julian L. Leibowitz</name><affiliation wicri:level="2"><nlm:aff id="aff0010">Department of Microbial Pathogenesis and Immunology, Texas A&M University, College of Medicine, College Station, TX 77843-1114, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Microbial Pathogenesis and Immunology, Texas A&M University, College of Medicine, College Station, TX 77843-1114</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></analytic><series><title level="j">Virus Research</title><idno type="ISSN">0168-1702</idno><idno type="eISSN">1872-7492</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>3' Untranslated Regions</term><term>5' Untranslated Regions</term><term>Animals</term><term>Conserved Sequence</term><term>Coronavirus (genetics)</term><term>Coronavirus (physiology)</term><term>Genome, Viral</term><term>Host-Pathogen Interactions</term><term>Humans</term><term>Models, Biological</term><term>Nucleic Acid Conformation</term><term>Promoter Regions, Genetic</term><term>RNA, Viral (chemistry)</term><term>RNA, Viral (genetics)</term><term>RNA, Viral (metabolism)</term><term>RNA-Binding Proteins (metabolism)</term><term>Transcription, Genetic</term><term>Virus Replication</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral ()</term><term>ARN viral (génétique)</term><term>ARN viral (métabolisme)</term><term>Animaux</term><term>Conformation d'acide nucléique</term><term>Coronavirus (génétique)</term><term>Coronavirus (physiologie)</term><term>Génome viral</term><term>Humains</term><term>Interactions hôte-pathogène</term><term>Modèles biologiques</term><term>Protéines de liaison à l'ARN (métabolisme)</term><term>Régions 3' non traduites</term><term>Régions 5' non traduites</term><term>Régions promotrices (génétique)</term><term>Réplication virale</term><term>Séquence conservée</term><term>Transcription génétique</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>RNA, Viral</term><term>RNA-Binding Proteins</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>3' Untranslated Regions</term><term>5' Untranslated Regions</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>ARN viral</term><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>ARN viral</term><term>Protéines de liaison à l'ARN</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Conserved Sequence</term><term>Genome, Viral</term><term>Host-Pathogen Interactions</term><term>Humans</term><term>Models, Biological</term><term>Nucleic Acid Conformation</term><term>Promoter Regions, Genetic</term><term>Transcription, Genetic</term><term>Virus Replication</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>ARN viral</term><term>Animaux</term><term>Conformation d'acide nucléique</term><term>Génome viral</term><term>Humains</term><term>Interactions hôte-pathogène</term><term>Modèles biologiques</term><term>Régions 3' non traduites</term><term>Régions 5' non traduites</term><term>Régions promotrices (génétique)</term><term>Réplication virale</term><term>Séquence conservée</term><term>Transcription génétique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0005"><label>•</label><p id="par0005">Models of conserved 5′ and 3′ betacoronavirus <italic>cis</italic>-acting RNA secondary structures are presented.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">The 5′ <italic>cis</italic>-acting sequences required for coronavirus replication extend into the first open reading frame.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">All 3′ <italic>cis</italic>-acting sequences required for coronavirus replication are contained in the 3′UTR.</p></list-item><list-item id="lsti0020"><label>•</label><p id="par0020">A putative molecular switch is present in the coronavirus 3′UTR.</p></list-item><list-item id="lsti0025"><label>•</label><p id="par0025">Proteins interacting with these <italic>cis</italic>-acting regions are reviewed.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Arbour, N" uniqKey="Arbour N">N. 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Miller</name></author><author><name sortKey="Goebel, S J" uniqKey="Goebel S">S.J. Goebel</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author><author><name sortKey="Masters, P S" uniqKey="Masters P">P.S. Masters</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Tennessee</li><li>Texas</li></region></list><tree><country name="États-Unis"><region name="Tennessee"><name sortKey="Yang, Dong" sort="Yang, Dong" uniqKey="Yang D" first="Dong" last="Yang">Dong Yang</name></region><name sortKey="Leibowitz, Julian L" sort="Leibowitz, Julian L" uniqKey="Leibowitz J" first="Julian L." last="Leibowitz">Julian L. Leibowitz</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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