SrasV1, Main, Curation, bibRecord, 005455

Assembling the SARS-CoV genome -- new method based on graph theoretical approach.

Identifieur interne : 005455 ( Main/Curation ); précédent : 005454; suivant : 005456

Assembling the SARS-CoV genome -- new method based on graph theoretical approach.

Auteurs : Jacek Błazewicz [Pologne] ; Marek Figlerowicz ; Piotr Formanowicz ; Marta Kasprzak ; Bartosz Nowierski ; Rafał Styszy Ski ; Lukasz Szajkowski ; Pawł Widera ; Mariusz Wiktorczyk

Source :

Acta biochimica Polonica [ 0001-527X ] ; 2004.

RBID : pubmed:15625570

Descripteurs français

KwdFr :
- Algorithmes, Biologie informatique (), Données de séquences moléculaires, Génome viral, Génomique (), Séquence nucléotidique, Virus du SRAS (génétique).
MESH :
- génétique : Virus du SRAS.
- Algorithmes, Biologie informatique, Données de séquences moléculaires, Génome viral, Génomique, Séquence nucléotidique.

English descriptors

KwdEn :
- Algorithms, Base Sequence, Computational Biology (methods), Genome, Viral, Genomics (methods), Molecular Sequence Data, SARS Virus (genetics).
MESH :
- genetics : SARS Virus.
- methods : Computational Biology, Genomics.
- Algorithms, Base Sequence, Genome, Viral, Molecular Sequence Data.

Abstract

Nowadays, scientists may learn a lot about the organisms studied just by analyzing their genetic material. This requires the development of methods of reading genomes with high accuracy. It has become clear that the knowledge of the changes occurring within a viral genome is indispensable for effective fighting of the pathogen. A good example is SARS-CoV, which was a cause of death of many people and frightened the entire world with its fast and hard to prevent propagation. Rapid development of sequencing methods, like shotgun sequencing or sequencing by hybridization (SBH), gives scientists a good tool for reading genomes. However, since sequencing methods can read fragments of up to 1000 bp only, methods for sequence assembling are required in order to read whole genomes. In this paper a new assembling method, based on graph theoretical approach, is presented. The method was tested on SARS-CoV and the results were compared to the outcome of other widely known methods.

DOI: 045104983
PubMed: 15625570

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pubmed:15625570

Le document en format XML

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Assembling the SARS-CoV genome -- new method based on graph theoretical approach.

Assembling the SARS-CoV genome -- new method based on graph theoretical approach.

Source :

Descripteurs français

English descriptors

Abstract

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Links to Exploration step

Le document en format XML

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