Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS.
Identifieur interne : 005231 ( Main/Curation ); précédent : 005230; suivant : 005232Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS.
Auteurs : Alexander Bukreyev [États-Unis] ; Elaine W. Lamirande ; Ursula J. Buchholz ; Leatrice N. Vogel ; William R. Elkins ; Marisa St Claire ; Brian R. Murphy ; Kanta Subbarao ; Peter L. CollinsSource :
- Lancet (London, England) [ 1474-547X ] ; 2004.
Descripteurs français
- KwdFr :
- ADN recombiné, Administration par voie nasale, Animaux, Anticorps antiviraux (sang), Glycoprotéine de spicule des coronavirus, Glycoprotéines membranaires (immunologie), Glycoprotéines membranaires (métabolisme), Immunité muqueuse, Irrigation thérapeutique, Muqueuse nasale (virologie), Muqueuse respiratoire (immunologie), Protéines de l'enveloppe virale (immunologie), Protéines de l'enveloppe virale (métabolisme), Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (immunologie), Trachée, Vaccination, Vaccins antiviraux (administration et posologie), Vaccins antiviraux (immunologie), Vaccins atténués, Vaccins contre les virus para-influenza, Virus du SRAS (immunologie), Virus du SRAS (isolement et purification), Virus du SRAS (métabolisme), Virus parainfluenza bovin de type 3 (immunologie), Virus parainfluenza bovin de type 3 (isolement et purification), Virus parainfluenza bovin de type 3 (métabolisme).
- MESH :
- administration et posologie : Vaccins antiviraux.
- immunologie : Glycoprotéines membranaires, Muqueuse respiratoire, Protéines de l'enveloppe virale, Syndrome respiratoire aigu sévère, Vaccins antiviraux, Virus du SRAS, Virus parainfluenza bovin de type 3.
- isolement et purification : Virus du SRAS, Virus parainfluenza bovin de type 3.
- métabolisme : Glycoprotéines membranaires, Protéines de l'enveloppe virale, Virus du SRAS, Virus parainfluenza bovin de type 3.
- sang : Anticorps antiviraux.
- virologie : Muqueuse nasale.
- ADN recombiné, Administration par voie nasale, Animaux, Glycoprotéine de spicule des coronavirus, Immunité muqueuse, Irrigation thérapeutique, Syndrome respiratoire aigu sévère, Trachée, Vaccination, Vaccins atténués, Vaccins contre les virus para-influenza.
English descriptors
- KwdEn :
- Administration, Intranasal, Animals, Antibodies, Viral (blood), Chlorocebus aethiops, DNA, Recombinant, Immunity, Mucosal, Membrane Glycoproteins (immunology), Membrane Glycoproteins (metabolism), Nasal Mucosa (virology), Parainfluenza Vaccines, Parainfluenza Virus 3, Bovine (immunology), Parainfluenza Virus 3, Bovine (isolation & purification), Parainfluenza Virus 3, Bovine (metabolism), Respiratory Mucosa (immunology), SARS Virus (immunology), SARS Virus (isolation & purification), SARS Virus (metabolism), Severe Acute Respiratory Syndrome (immunology), Severe Acute Respiratory Syndrome (prevention & control), Spike Glycoprotein, Coronavirus, Therapeutic Irrigation, Trachea, Vaccination, Vaccines, Attenuated, Viral Envelope Proteins (immunology), Viral Envelope Proteins (metabolism), Viral Vaccines (administration & dosage), Viral Vaccines (immunology).
- MESH :
- chemical , administration & dosage : Viral Vaccines.
- chemical , blood : Antibodies, Viral.
- chemical , immunology : Membrane Glycoproteins, Viral Envelope Proteins, Viral Vaccines.
- chemical , metabolism : Membrane Glycoproteins, Viral Envelope Proteins.
- immunology : Parainfluenza Virus 3, Bovine, Respiratory Mucosa, SARS Virus, Severe Acute Respiratory Syndrome.
- isolation & purification : Parainfluenza Virus 3, Bovine, SARS Virus.
- metabolism : Parainfluenza Virus 3, Bovine, SARS Virus.
- prevention & control : Severe Acute Respiratory Syndrome.
- virology : Nasal Mucosa.
- Administration, Intranasal, Animals, Chlorocebus aethiops, DNA, Recombinant, Immunity, Mucosal, Parainfluenza Vaccines, Spike Glycoprotein, Coronavirus, Therapeutic Irrigation, Trachea, Vaccination, Vaccines, Attenuated.
Abstract
The outbreak of severe acute respiratory syndrome (SARS) in 2002 was caused by a previously unknown coronavirus-SARS coronavirus (SARS-CoV). We have developed an experimental SARS vaccine for direct immunisation of the respiratory tract, the major site of SARS- coronavirus transmission and disease.
DOI: 10.1016/S0140-6736(04)16501-X
PubMed: 15220033
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :002D00
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :002D00
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :002B82
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000910
- to stream Ncbi, to step Curation: Pour aller vers cette notice dans l'étape Curation :000910
- to stream Ncbi, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000910
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :005625
Links to Exploration step
pubmed:15220033Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS.</title>
<author><name sortKey="Bukreyev, Alexander" sort="Bukreyev, Alexander" uniqKey="Bukreyev A" first="Alexander" last="Bukreyev">Alexander Bukreyev</name>
<affiliation wicri:level="2"><nlm:affiliation>Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. AB176v@nih.gov</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lamirande, Elaine W" sort="Lamirande, Elaine W" uniqKey="Lamirande E" first="Elaine W" last="Lamirande">Elaine W. Lamirande</name>
</author>
<author><name sortKey="Buchholz, Ursula J" sort="Buchholz, Ursula J" uniqKey="Buchholz U" first="Ursula J" last="Buchholz">Ursula J. Buchholz</name>
</author>
<author><name sortKey="Vogel, Leatrice N" sort="Vogel, Leatrice N" uniqKey="Vogel L" first="Leatrice N" last="Vogel">Leatrice N. Vogel</name>
</author>
<author><name sortKey="Elkins, William R" sort="Elkins, William R" uniqKey="Elkins W" first="William R" last="Elkins">William R. Elkins</name>
</author>
<author><name sortKey="St Claire, Marisa" sort="St Claire, Marisa" uniqKey="St Claire M" first="Marisa" last="St Claire">Marisa St Claire</name>
</author>
<author><name sortKey="Murphy, Brian R" sort="Murphy, Brian R" uniqKey="Murphy B" first="Brian R" last="Murphy">Brian R. Murphy</name>
</author>
<author><name sortKey="Subbarao, Kanta" sort="Subbarao, Kanta" uniqKey="Subbarao K" first="Kanta" last="Subbarao">Kanta Subbarao</name>
</author>
<author><name sortKey="Collins, Peter L" sort="Collins, Peter L" uniqKey="Collins P" first="Peter L" last="Collins">Peter L. Collins</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2004">2004</date>
<idno type="RBID">pubmed:15220033</idno>
<idno type="pmid">15220033</idno>
<idno type="doi">10.1016/S0140-6736(04)16501-X</idno>
<idno type="wicri:Area/PubMed/Corpus">002D00</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002D00</idno>
<idno type="wicri:Area/PubMed/Curation">002D00</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002D00</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002B82</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002B82</idno>
<idno type="wicri:Area/Ncbi/Merge">000910</idno>
<idno type="wicri:Area/Ncbi/Curation">000910</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000910</idno>
<idno type="wicri:Area/Main/Merge">005625</idno>
<idno type="wicri:Area/Main/Curation">005231</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS.</title>
<author><name sortKey="Bukreyev, Alexander" sort="Bukreyev, Alexander" uniqKey="Bukreyev A" first="Alexander" last="Bukreyev">Alexander Bukreyev</name>
<affiliation wicri:level="2"><nlm:affiliation>Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. AB176v@nih.gov</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892</wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lamirande, Elaine W" sort="Lamirande, Elaine W" uniqKey="Lamirande E" first="Elaine W" last="Lamirande">Elaine W. Lamirande</name>
</author>
<author><name sortKey="Buchholz, Ursula J" sort="Buchholz, Ursula J" uniqKey="Buchholz U" first="Ursula J" last="Buchholz">Ursula J. Buchholz</name>
</author>
<author><name sortKey="Vogel, Leatrice N" sort="Vogel, Leatrice N" uniqKey="Vogel L" first="Leatrice N" last="Vogel">Leatrice N. Vogel</name>
</author>
<author><name sortKey="Elkins, William R" sort="Elkins, William R" uniqKey="Elkins W" first="William R" last="Elkins">William R. Elkins</name>
</author>
<author><name sortKey="St Claire, Marisa" sort="St Claire, Marisa" uniqKey="St Claire M" first="Marisa" last="St Claire">Marisa St Claire</name>
</author>
<author><name sortKey="Murphy, Brian R" sort="Murphy, Brian R" uniqKey="Murphy B" first="Brian R" last="Murphy">Brian R. Murphy</name>
</author>
<author><name sortKey="Subbarao, Kanta" sort="Subbarao, Kanta" uniqKey="Subbarao K" first="Kanta" last="Subbarao">Kanta Subbarao</name>
</author>
<author><name sortKey="Collins, Peter L" sort="Collins, Peter L" uniqKey="Collins P" first="Peter L" last="Collins">Peter L. Collins</name>
</author>
</analytic>
<series><title level="j">Lancet (London, England)</title>
<idno type="eISSN">1474-547X</idno>
<imprint><date when="2004" type="published">2004</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Intranasal</term>
<term>Animals</term>
<term>Antibodies, Viral (blood)</term>
<term>Chlorocebus aethiops</term>
<term>DNA, Recombinant</term>
<term>Immunity, Mucosal</term>
<term>Membrane Glycoproteins (immunology)</term>
<term>Membrane Glycoproteins (metabolism)</term>
<term>Nasal Mucosa (virology)</term>
<term>Parainfluenza Vaccines</term>
<term>Parainfluenza Virus 3, Bovine (immunology)</term>
<term>Parainfluenza Virus 3, Bovine (isolation & purification)</term>
<term>Parainfluenza Virus 3, Bovine (metabolism)</term>
<term>Respiratory Mucosa (immunology)</term>
<term>SARS Virus (immunology)</term>
<term>SARS Virus (isolation & purification)</term>
<term>SARS Virus (metabolism)</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
<term>Severe Acute Respiratory Syndrome (prevention & control)</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Therapeutic Irrigation</term>
<term>Trachea</term>
<term>Vaccination</term>
<term>Vaccines, Attenuated</term>
<term>Viral Envelope Proteins (immunology)</term>
<term>Viral Envelope Proteins (metabolism)</term>
<term>Viral Vaccines (administration & dosage)</term>
<term>Viral Vaccines (immunology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>ADN recombiné</term>
<term>Administration par voie nasale</term>
<term>Animaux</term>
<term>Anticorps antiviraux (sang)</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Glycoprotéines membranaires (immunologie)</term>
<term>Glycoprotéines membranaires (métabolisme)</term>
<term>Immunité muqueuse</term>
<term>Irrigation thérapeutique</term>
<term>Muqueuse nasale (virologie)</term>
<term>Muqueuse respiratoire (immunologie)</term>
<term>Protéines de l'enveloppe virale (immunologie)</term>
<term>Protéines de l'enveloppe virale (métabolisme)</term>
<term>Syndrome respiratoire aigu sévère ()</term>
<term>Syndrome respiratoire aigu sévère (immunologie)</term>
<term>Trachée</term>
<term>Vaccination</term>
<term>Vaccins antiviraux (administration et posologie)</term>
<term>Vaccins antiviraux (immunologie)</term>
<term>Vaccins atténués</term>
<term>Vaccins contre les virus para-influenza</term>
<term>Virus du SRAS (immunologie)</term>
<term>Virus du SRAS (isolement et purification)</term>
<term>Virus du SRAS (métabolisme)</term>
<term>Virus parainfluenza bovin de type 3 (immunologie)</term>
<term>Virus parainfluenza bovin de type 3 (isolement et purification)</term>
<term>Virus parainfluenza bovin de type 3 (métabolisme)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Viral Vaccines</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Membrane Glycoproteins</term>
<term>Viral Envelope Proteins</term>
<term>Viral Vaccines</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Membrane Glycoproteins</term>
<term>Viral Envelope Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Vaccins antiviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Glycoprotéines membranaires</term>
<term>Muqueuse respiratoire</term>
<term>Protéines de l'enveloppe virale</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Vaccins antiviraux</term>
<term>Virus du SRAS</term>
<term>Virus parainfluenza bovin de type 3</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Parainfluenza Virus 3, Bovine</term>
<term>Respiratory Mucosa</term>
<term>SARS Virus</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Parainfluenza Virus 3, Bovine</term>
<term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Virus du SRAS</term>
<term>Virus parainfluenza bovin de type 3</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Parainfluenza Virus 3, Bovine</term>
<term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Glycoprotéines membranaires</term>
<term>Protéines de l'enveloppe virale</term>
<term>Virus du SRAS</term>
<term>Virus parainfluenza bovin de type 3</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps antiviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Muqueuse nasale</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Nasal Mucosa</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Administration, Intranasal</term>
<term>Animals</term>
<term>Chlorocebus aethiops</term>
<term>DNA, Recombinant</term>
<term>Immunity, Mucosal</term>
<term>Parainfluenza Vaccines</term>
<term>Spike Glycoprotein, Coronavirus</term>
<term>Therapeutic Irrigation</term>
<term>Trachea</term>
<term>Vaccination</term>
<term>Vaccines, Attenuated</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>ADN recombiné</term>
<term>Administration par voie nasale</term>
<term>Animaux</term>
<term>Glycoprotéine de spicule des coronavirus</term>
<term>Immunité muqueuse</term>
<term>Irrigation thérapeutique</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Trachée</term>
<term>Vaccination</term>
<term>Vaccins atténués</term>
<term>Vaccins contre les virus para-influenza</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The outbreak of severe acute respiratory syndrome (SARS) in 2002 was caused by a previously unknown coronavirus-SARS coronavirus (SARS-CoV). We have developed an experimental SARS vaccine for direct immunisation of the respiratory tract, the major site of SARS- coronavirus transmission and disease.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005231 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 005231 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= Main |étape= Curation |type= RBID |clé= pubmed:15220033 |texte= Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Curation/RBID.i -Sk "pubmed:15220033" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Curation/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
This area was generated with Dilib version V0.6.33. |