SARS: An Emerging Global Microbial Threat.
Identifieur interne : 005103 ( Main/Curation ); précédent : 005102; suivant : 005104SARS: An Emerging Global Microbial Threat.
Auteurs : James M. HughesSource :
- Transactions of the American Clinical and Climatological Association [ 0065-7778 ] ; 2004.
Descripteurs français
- KwdFr :
- Animaux, Animaux sauvages (virologie), Flambées de maladies (), Humains, Microbiologie alimentaire, Santé mondiale, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (transmission), Syndrome respiratoire aigu sévère (virologie), Syndrome respiratoire aigu sévère (épidémiologie), Virus du SRAS (isolement et purification), Virus du SRAS (pathogénicité).
- MESH :
- isolement et purification : Virus du SRAS.
- pathogénicité : Virus du SRAS.
- virologie : Animaux sauvages, Syndrome respiratoire aigu sévère.
- épidémiologie : Syndrome respiratoire aigu sévère.
- Animaux, Flambées de maladies, Humains, Microbiologie alimentaire, Santé mondiale, Syndrome respiratoire aigu sévère.
English descriptors
- KwdEn :
- Animals, Animals, Wild (virology), Disease Outbreaks (prevention & control), Food Microbiology, Global Health, Humans, SARS Virus (isolation & purification), SARS Virus (pathogenicity), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (prevention & control), Severe Acute Respiratory Syndrome (transmission), Severe Acute Respiratory Syndrome (virology).
- MESH :
- epidemiology : Severe Acute Respiratory Syndrome.
- isolation & purification : SARS Virus.
- pathogenicity : SARS Virus.
- prevention & control : Disease Outbreaks, Severe Acute Respiratory Syndrome.
- transmission : Severe Acute Respiratory Syndrome.
- virology : Animals, Wild, Severe Acute Respiratory Syndrome.
- Animals, Food Microbiology, Global Health, Humans.
Abstract
In March 2003, the Institute of Medicine published an update to its 1992 landmark report on emerging infections. The new report, Microbial Threats to Health: Emergence, Detection, and Response, describes the current spectrum of global microbial threats, factors affecting their emergence or resurgence, and measures that should be undertaken to effectively address them. Coincident with this publication came increasing reports of severe atypical pneumonia of unknown etiology among persons in southeast Asia. This new disease, designated severe acute respiratory syndrome (SARS), spread globally in a matter of weeks, infecting primarily close contacts of index patients (e.g., household members and healthcare workers caring for index patients) but also resulting in community transmission in some areas. An unprecedented worldwide collaborative effort was undertaken to determine the cause of the illness and implement prevention measures. A previously unrecognized coronavirus was identified as the causative agent, and health officials throughout the world struggled to implement measures to contain its spread, including isolation of suspect SARS cases and quarantine of exposed persons. The emergence of SARS is a timely reminder of the need to expect the unexpected and to ensure strong national and global public health partnerships when preparing for and responding to infectious diseases. Effectively addressing the threat of SARS will require enhanced global infectious disease surveillance, the development of rapid diagnostics, new therapies, and vaccines, implementation of aggressive evidence-based infection control strategies, and effective communication.
Url:
PubMed: 17060979
PubMed Central: 2263793
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PMC:2263793Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>In March 2003, the Institute of Medicine published an update to its 1992 landmark report on emerging infections. The new report, Microbial Threats to Health: Emergence, Detection, and Response, describes the current spectrum of global microbial threats, factors affecting their emergence or resurgence, and measures that should be undertaken to effectively address them. Coincident with this publication came increasing reports of severe atypical pneumonia of unknown etiology among persons in southeast Asia. This new disease, designated severe acute respiratory syndrome (SARS), spread globally in a matter of weeks, infecting primarily close contacts of index patients (e.g., household members and healthcare workers caring for index patients) but also resulting in community transmission in some areas. An unprecedented worldwide collaborative effort was undertaken to determine the cause of the illness and implement prevention measures. A previously unrecognized coronavirus was identified as the causative agent, and health officials throughout the world struggled to implement measures to contain its spread, including isolation of suspect SARS cases and quarantine of exposed persons. The emergence of SARS is a timely reminder of the need to expect the unexpected and to ensure strong national and global public health partnerships when preparing for and responding to infectious diseases. Effectively addressing the threat of SARS will require enhanced global infectious disease surveillance, the development of rapid diagnostics, new therapies, and vaccines, implementation of aggressive evidence-based infection control strategies, and effective communication.</p>
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